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Cytokines And Adhesion Molecules In Lung Inflammation


Cytokines And Adhesion Molecules In Lung Inflammation
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Cytokines And Adhesion Molecules In Lung Inflammation


Cytokines And Adhesion Molecules In Lung Inflammation
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Author :
language : en
Publisher:
Release Date : 2006

Cytokines And Adhesion Molecules In Lung Inflammation written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.




Adhesion Molecules And The Lung


Adhesion Molecules And The Lung
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Author : P. A. Ward
language : en
Publisher: CRC Press
Release Date : 1996-01-23

Adhesion Molecules And The Lung written by P. A. Ward and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-01-23 with Science categories.


This state-of-the-art reference outlines current knowledge of the structure, transcriptional regulation, and binding characteristics of vascular and leukocyte adhesion molecules and their ligands delineating the nature of adhesion molecule interactions in lung morphogenesis and repair, tumor metastasis, and experimental models of inflammatory lung injury.



Cells And Cytokines In Lung Inflammation


Cells And Cytokines In Lung Inflammation
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Author : Michel Chignard
language : en
Publisher:
Release Date : 1994

Cells And Cytokines In Lung Inflammation written by Michel Chignard and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Medical categories.


This volume compares the results of investigators on the mechanisms of generation, interaction, and modulation of inflammatory cytokines and their respective cell origins and/or targets. The book, divided roughly according to cell species, advances what is currently known about the synergism of early and late mediators on resident and newly recruited target cells.



Acute Lung Injury


Acute Lung Injury
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Author : Geoffrey J. Bellingan
language : en
Publisher: John Wiley & Sons
Release Date : 2000

Acute Lung Injury written by Geoffrey J. Bellingan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Animal welfare categories.


This book provides a comprehensive and up to date picture of the molecular mechanisms underlying acute lung injury, focusing both on the mechanisms of injury and of repair. Topics covered include the cells involved, their injurious products including pro-inflammatory cytokines, proteases and free radical species as well as the fibrotic response and its molecular regulation, the role of the immune system, airway repair and remodelling and transcription factors regulating inflammation. All the chapters are written by experts in their field and reflect the lecture given by these authors at a recent international meeting also entitled " Acute lung injury: from inflammation to repair", held as part of the ongoing Molecular Pathology Annual symposia at University College London. The meeting gathered together a wide range of scientists and clinicians all of whom are at the cutting edge of inflammation and repair as it relates to acute lung injury. It is the breadth of approach that makes the volume so useful.



Role Of Adhesion Molecules And Chemokines In Lung Inflammation


Role Of Adhesion Molecules And Chemokines In Lung Inflammation
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Author : Abdul Basit
language : en
Publisher:
Release Date : 2006

Role Of Adhesion Molecules And Chemokines In Lung Inflammation written by Abdul Basit and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.


My findings have firmly established the role of ICAM-1 and LFA-1 in neutrophil recruitment into lung and have opened up unexpected directions in the role of chemokines in this process.



New Targets In Inflammation


New Targets In Inflammation
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Author : N. Bazan
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

New Targets In Inflammation written by N. Bazan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


For the past 100 years the mainstay of therapy for rheumatoid arthritis (RA) has been aspirin or other drugs of the non-steroid anti-inflammatory group. In 1971 Vane pro posed that both the beneficial and toxic actions of these drugs was through inhibition of prostaglandin synthesis. The recent discovery that prostaglandins responsible for pain and other symptoms at inflammatory foci are synthesized by an inducible cyclooxygenase (COX-2) that is encoded by a gene distinct from that of the consti tutive enzyme (COX-I) provided a new target for therapy of RA. A drug that would selectively inhibit COX-2 would hopefully produce the symptomatic benefit provided by existing NSAIDs without the gastrointestinal and renal toxicity due to the inhibition of COX-I. Drugs selective for COX-2 are now available. Experimental studies have shown them to be effective with minimal toxicity, and in clinical trials gastric and renal toxicities are less. Highly selective COX-2 inhibitors, perhaps designed with knowledge of the crystal structures of COX-I and COX-2, are also available. Other experimental studies, including those in animals lacking effective genes for COX-lor COX-2 and in experimental carcinomas, suggest there is still much to be learned of the pathophysiological functions of these enzymes. The inflammatory response is a complex reaction involving many mediators that derive from white blood cells, endothelial cells and other tissues. Preliminary data have revealed that inhibitors of the cytokines and adhesion molecules that play a crucial role in the migration of white cells to inflammatory sites may be useful in RA.



Adhesion Molecules In Health And Disease


Adhesion Molecules In Health And Disease
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Author : Paul
language : en
Publisher: CRC Press
Release Date : 1997-05-16

Adhesion Molecules In Health And Disease written by Paul and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-05-16 with Science categories.


Provides an overview of the structure, transcription regulation and binding characteristics of cellular adhesion molecules and their ligands in the maintenance of function, immunological reactions and inflammatory processes with organ systems. The text examines the role of adhesion molecules in biological processes such as morphogenesis, blood coagulation, tumour metastasis, bone tissue remodelling and transplant rejection.



Adhesion Molecules In Allergic Disease


Adhesion Molecules In Allergic Disease
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Author : Bruce S. Bochner
language : en
Publisher: CRC Press
Release Date : 2020-08-18

Adhesion Molecules In Allergic Disease written by Bruce S. Bochner and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-18 with Cooking categories.


This unique resource-the first book of its kind exclusively devoted to the subject-offers timely coverage of the cells, mechanisms, and proteins involved in allergic inflammation, emphasizing the latest advances in local cell recruitment.



Cytokine Ion Channel Interactions In Pulmonary Inflammation


Cytokine Ion Channel Interactions In Pulmonary Inflammation
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Author : István Vadász
language : en
Publisher: Frontiers Media SA
Release Date : 2019-01-24

Cytokine Ion Channel Interactions In Pulmonary Inflammation written by István Vadász and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-24 with categories.


This Research Topic assembles original contributions and reviews from an international consortium of PIs related to interactions between pro-inflammatory cytokines and ion channels during acute lung injury and chronic heart failure.



T Lymphocyte And Inflammatory Cell Research In Asthma


T Lymphocyte And Inflammatory Cell Research In Asthma
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Author : G. Jolles
language : en
Publisher: Academic Press
Release Date : 2012-12-02

T Lymphocyte And Inflammatory Cell Research In Asthma written by G. Jolles and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.


It is well established that asthma is an inflammatory disease of the airway mucosa and drugs like inhaled glucocorticoids are now commonly introduced early in therapy. A characteristic feature of this disease is the vast number of eosinophils in airway tissue, although many other migratory and resident inflammatory cells with the capacity to synthesize and release cytokines and putative asthma mediators are present in the inflamed mucosa. The cross-talk between lymphocytes and these cells and the role of cytokines in complex biological networks are currently areas of intense research. This volume gathers together chapters and discussions on the biology of immunocompetent and inflammatory cells, cellular interplay and communication, and on the relative importance of cells and mediators in disease. It should help contribute to further insights into the pathology of asthma and to the development of novel efficacious drugs for the treatment of asthma and related respiratory disorders.