Cytoskeletal Regulation Of Immune Response

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Cytoskeletal Regulation Of Immune Response
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Author : Sudha Kumari
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-04
Cytoskeletal Regulation Of Immune Response written by Sudha Kumari and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-04 with Science categories.
Molecular Biology Of The Cell
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Author :
language : en
Publisher:
Release Date : 2004
Molecular Biology Of The Cell written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Cells categories.
Cytoskeleton Dynamics As Master Regulator Of Organelle Reorganization And Intracellular Signaling For Cell Cell Competition
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Author : Noa B. Martin-Cofreces
language : en
Publisher: Frontiers Media SA
Release Date : 2021-12-30
Cytoskeleton Dynamics As Master Regulator Of Organelle Reorganization And Intracellular Signaling For Cell Cell Competition written by Noa B. Martin-Cofreces and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-30 with Science categories.
Introduction For Liver 3d Bioprinting Book 2
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Author : Edenilson Brandl
language : en
Publisher: Edenilson Brandl
Release Date : 2024-05-19
Introduction For Liver 3d Bioprinting Book 2 written by Edenilson Brandl and has been published by Edenilson Brandl this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-19 with Medical categories.
The field of 3D bioprinting represents a revolutionary frontier in biomedical research and therapeutic applications. As a promising technology, it offers immense potential in tissue engineering and regenerative medicine, particularly for complex organs such as the liver. "INTRODUCTION FOR LIVER 3D BIOPRINTING – BOOK 2: INTRODUCTION TO CELL BIOLOGY + THE 3D BIOPRINTING" delves into the intricate biological processes and cutting-edge methodologies that underpin this transformative field. This book is the second in a series aimed at providing a comprehensive overview of the key scientific principles and technological advancements essential for mastering liver 3D bioprinting. Our journey begins with an in-depth exploration of cell biology, setting a strong foundation for understanding the cellular mechanisms critical to successful bioprinting. We then transition to the specialized aspects of 3D bioprinting technology, bridging theoretical knowledge with practical application. Through a detailed examination of topics such as the Krebs cycle, cellular signaling, and metabolic regulation, this book elucidates the complexities of cellular functions and their implications in tissue engineering. We also cover the technological nuances of 3D bioprinting, including material selection, scaffold design, and the operational principles of bioprinters. This text serves not only as an educational resource but also as a practical guide for researchers, practitioners, and students eager to contribute to the advancement of 3D bioprinting. By fostering a deeper understanding of the biological and technological challenges and opportunities in this field, we aim to inspire innovation and progress in the development of bioengineered liver tissues. As we embark on this exploration, we express our gratitude to the scientific community for their relentless pursuit of knowledge and innovation. We hope this book will serve as a valuable tool in your endeavors and contribute meaningfully to the exciting future of liver 3D bioprinting.
The Plant Cytoskeleton
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Author : Bo Liu
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-11-23
The Plant Cytoskeleton written by Bo Liu and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-23 with Science categories.
Plant cells house highly dynamic cytoskeletal networks of microtubules and actin microfilaments. They constantly undergo remodeling to fulfill their roles in supporting cell division, enlargement, and differentiation. Following early studies on structural aspects of the networks, recent breakthroughs have connected them with more and more intracellular events essential for plant growth and development. Advanced technologies in cell biology (live-cell imaging in particular), molecular genetics, genomics, and proteomics have revolutionized this field of study. Stories summarized in this book may inspire enthusiastic scientists to pursue new directions toward understanding functions of the plant cytoskeleton. The Plant Cytoskeleton is divided into three sections: 1) Molecular Basis of the Plant Cytoskeleton; 2) Cytoskeletal Reorganization in Plant Cell Division; and 3) The Cytoskeleton in Plant Growth and Development. This book is aimed at serving as a resource for anyone who wishes to learn about the plant cytoskeleton beyond ordinary textbooks.
Biomedical Index To Phs Supported Research
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Author :
language : en
Publisher:
Release Date : 1990
Biomedical Index To Phs Supported Research written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Medicine categories.
Mass Spectrometry And Nutrition Research
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Author : Laurent Bernard Fay
language : en
Publisher: Royal Society of Chemistry
Release Date : 2010
Mass Spectrometry And Nutrition Research written by Laurent Bernard Fay and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.
Mass spectrometry has developed into a platform for the assessment of health, sensory, quality and safety aspects of food. Current nutrition research focuses on unravelling the link between acute or chronic dietary and nutrient intake and the physiological effects at cellular, tissue and whole body level. The bioavailability and bioefficacy of food constituents and dose-effect correlations are key to understanding the impact of food on defined health outcomes. To generate this information, appropriate analytical tools are required to identify and quantify minute amounts of individual compounds in highly complex matrices (such as food or biological fluids) and to monitor molecular changes in the body in a highly specific and sensitive manner. Mass spectrometry has become the method of choice for such work and now has broad applications throughout all areas of nutrition research. This book focuses the contribution of mass spectrometry to the advancement of nutrition research. Aimed and students, teachers and researchers, it provides a link between nutrition and analytical biochemistry. It guides nutritionists to the appropriate techniques for their work and introduces analytical biochemists to new fields of application in nutrition and health. The first part of the book is dedicated to the assessment of macro- and micro-nutrient status with a view to making dietary recommendations for the treatment of diet-related diseases. The second part shows how mass spectrometry has changed nutrition research in fields like energy metabolism, body composition, protein turnover, immune modulation and cardiovascular health.
Case Studies In Immunology
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Author : Raif Geha
language : en
Publisher: Garland Science
Release Date : 2016-02-05
Case Studies In Immunology written by Raif Geha and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-05 with Medical categories.
Case Studies in Immunology, Seventh Edition is intended for medical students and undergraduate and graduate students in immunology. It presents major topics of immunology through a selection of clinical cases that reinforce and extend the basic science. Each case history is preceded by essential scientific facts about the immunological mechanisms o
Actin Cytoskeleton In Cancer Progression And Metastasis Part B
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Author :
language : en
Publisher: Academic Press
Release Date : 2020-10-14
Actin Cytoskeleton In Cancer Progression And Metastasis Part B written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-14 with Science categories.
Actin Cytoskeleton in Cancer Progression and Metastasis (Part B), Volume 356 in the International Review of Cell and Molecular Biology series, provides an overview on the roles of the actin cytoskeleton and its key structural regulators, including WASp, Paxillin, Myosin, Testin, L-Plastin and profilin, and in central processes underlying cancer progression and metastasis, such as changes in cell morphology and gene expression, acquisition of migratory and invasive capabilities, and evasion from the immune response. Specific chapters in this release cover Actin dynamics during tumor cell dissemination, Actin cytoskeleton remodeling during cancer cell migration, Cytoskeletal Mechanics Drives Heterogeneity in Epithelial Ovarian Cancer, and much more. - Provides comprehensive and timely reviews on actin cytoskeleton and its regulators in cancer biology - Offers a wide range of perspectives for basic and translational research - Discusses opportunities and challenges for translating knowledge of tumor cell actin cytoskeleton into clinical applications
Regulation Of Immune System Cell Functions By Protein Kinase C
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Author : Noah Isakov
language : en
Publisher: Frontiers E-books
Release Date : 2014-11-11
Regulation Of Immune System Cell Functions By Protein Kinase C written by Noah Isakov and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-11 with Immunologic diseases. Allergy categories.
Members of the protein kinase C (PKC) family of Ser/Thr kinases are encoded by nine distinct but closely related genes, which give rise to more than 12 different protein isoforms via a mechanism of alternative RNA splicing. Most PKC proteins are ubiquitously expressed and participate in a plethora of functions in most cell types. A majority of PKC isoforms is also expressed in cells of the immune system in which they are involved in signal transduction downstream of a range of surface receptors, including the antigen receptors on T and B lymphocytes. PKC proteins are central to signal initiation and propagation, and to the regulation of processes leading to immune cell proliferation, differentiation, homing and survival. As a result, PKC proteins directly impact on the quality and quantity of immune responses and indirectly on the host resistance to pathogens and tendency to develop immune deficiencies and autoimmune diseases. A significant progress was made in recent years in understanding the regulation of PKC enzymes, their mechanism of action and their role in determining immunocyte behavior This volume reviews the most significant contributions made in the field of immune cell regulation by PKC enzymes. Several manuscripts are devoted to the role of distinct PKC isoforms in the regulation of selected immunocyte responses. Additional manuscripts review more general mechanisms of regulation of PKC enzymes, either by post-translational modifications, such as phosphorylation or controlled proteolysis, or by interaction with different binding proteins that may alter the conformation, activity and subcellular location of PKC. Both types of mechanisms can introduce conformational changes in the molecule, which may affect its ability to interact with cofactors, ATP, or substrates. This topic will be followed by a discussion on the positive and negative impact of individual PKC isoforms on cell cycle regulation. A second section of this volume concentrates on selected topics relevant to role of the novel PKC isoform, PKC-theta, in T lymphocyte function. PKC-theta plays important and some non-redundant roles in T cell activation and is a key isoform that recruits to the immunological synapse - the surface membrane area in T cells that comes in direct contact with antigen presenting cells. The immunological synapse is formed in T cells within seconds following the engagement of the TCR by a peptide-bound MHC molecule on the surface of antigen-presenting cells. It serves as a platform for receptors, adaptor proteins, and effector molecules, which assemble into multimolecular activation complexes required for signal transduction. The unique ability of PKC-theta to activate the NF-kB, AP-1 and NF-AT transcription factors is well established, and recent studies contributed essential information on the mechanisms involved in the recruitment of PKC-theta to the center of the immunological synapse and the nature of its substrates and the role of their phosphorylated forms in signal transduction. Additional review manuscripts will describe the unique behavior of PKC-theta in regulatory T cells and its role in the regulation of other cell populations, including those of the innate immune response. This volume brings together leading experts from different disciplines that review the most recent discoveries and offer new perspectives on the contributions of PKC isoforms to biochemical processes and signaling events in different immune cell populations and their impact on the overall host immune response.