Deep Learning For Genome Wide Association Studies And The Impact Of Snp Locations
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Deep Learning For Genome Wide Association Studies And The Impact Of Snp Locations
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Author : Songyuan Ji
language : en
Publisher:
Release Date : 2019
Deep Learning For Genome Wide Association Studies And The Impact Of Snp Locations written by Songyuan Ji and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with categories.
The study of Single Nucleotide Polymorphisms (SNPs) associated with human diseases is important for identifying pathogenic genetic variants and illuminating the genetic architecture of complex diseases. A Genome-wide association study (GWAS) examines genetic variation in different individuals and detects disease related SNPs. The traditional machine learning methods always use SNPs data as a sequence to analyze and process and thus may overlook the complex interacting relationships among multiple genetic factors. In this thesis, we propose a new hybrid deep learning approach to identify susceptibility SNPs associated with colorectal cancer. A set of SNPs variants were first selected by a hybrid feature selection algorithm, and then organized as 3D images using a selection of space-filling curve models. A multi-layer deep Convolutional Neural Network was constructed and trained using those images. We found that images generated using the space-filling curve model that preserve the original SNP locations in the genome yield the best classification performance. We also report a set of high risk SNPs associate with colorectal cancer as the result of the deep neural network model.
Machine Learning In Genome Wide Association Studies
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Author : Ting Hu
language : en
Publisher: Frontiers Media SA
Release Date : 2020-12-15
Machine Learning In Genome Wide Association Studies written by Ting Hu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-15 with Science categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Genome Wide Association Studies And Genomic Selection For Crop Improvement In The Era Of Big Data
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Author : Nunzio D’Agostino
language : en
Publisher: Frontiers Media SA
Release Date : 2023-05-05
Genome Wide Association Studies And Genomic Selection For Crop Improvement In The Era Of Big Data written by Nunzio D’Agostino and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-05 with Science categories.
Genome Wide Association Studies
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Author : Krishnarao Appasani
language : en
Publisher: Cambridge University Press
Release Date : 2016-01-14
Genome Wide Association Studies written by Krishnarao Appasani and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-14 with Medical categories.
Experts from academia and industry highlight the potential of genome-wide association studies from basic science to clinical and biotechnological/pharmaceutical applications.
Neural Information Processing
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Author : Long Cheng
language : en
Publisher: Springer
Release Date : 2018-12-03
Neural Information Processing written by Long Cheng and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-03 with Computers categories.
The seven-volume set of LNCS 11301-11307 constitutes the proceedings of the 25th International Conference on Neural Information Processing, ICONIP 2018, held in Siem Reap, Cambodia, in December 2018. The 401 full papers presented were carefully reviewed and selected from 575 submissions. The papers address the emerging topics of theoretical research, empirical studies, and applications of neural information processing techniques across different domains. The 5th volume, LNCS 11305, is organized in topical sections on prediction; pattern recognition; and word, text and document processing.
Artificial Neural Networks Icann 2010
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Author : Konstantinos Diamantaras
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-03
Artificial Neural Networks Icann 2010 written by Konstantinos Diamantaras and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-03 with Computers categories.
This three volume set LNCS 6352, LNCS 6353, and LNCS 6354 constitutes the refereed proceedings of the 20th International Conference on Artificial Neural Networks, ICANN 2010, held in Thessaloniki, Greece, in September 2010. The 102 revised full papers, 68 short papers and 29 posters presented were carefully reviewed and selected from 241 submissions. The first volume is divided in topical sections on ANN applications, Bayesian ANN, bio inspired – spiking ANN, biomedical ANN, computational neuroscience, feature selection/parameter identification and dimensionality reduction, filtering, genetic – evolutionary algorithms, and image – video and audio processing.
Computational Epigenetics In Human Diseases Cell Differentiation And Cell Reprogramming Volume I
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Author : Jianzhong Su
language : en
Publisher: Frontiers Media SA
Release Date : 2021-02-24
Computational Epigenetics In Human Diseases Cell Differentiation And Cell Reprogramming Volume I written by Jianzhong Su and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-24 with Science categories.
Machine Learning Advanced Dynamic Omics Data Analysis For Precision Medicine
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Author : Tao Zeng
language : en
Publisher: Frontiers Media SA
Release Date : 2020-03-30
Machine Learning Advanced Dynamic Omics Data Analysis For Precision Medicine written by Tao Zeng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-30 with categories.
Machine Learning With Radiation Oncology Big Data
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Author : Jun Deng
language : en
Publisher: Frontiers Media SA
Release Date : 2019-01-21
Machine Learning With Radiation Oncology Big Data written by Jun Deng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-21 with categories.
Neural Information Processing
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Author : Sabri Arik
language : en
Publisher: Springer
Release Date : 2015-11-21
Neural Information Processing written by Sabri Arik and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-21 with Computers categories.
The four volume set LNCS 9489, LNCS 9490, LNCS 9491, and LNCS 9492 constitutes the proceedings of the 22nd International Conference on Neural Information Processing, ICONIP 2015, held in Istanbul, Turkey, in November 2015. The 231 full papers presented were carefully reviewed and selected from 375 submissions. The 4 volumes represent topical sections containing articles on Learning Algorithms and Classification Systems; Artificial Intelligence and Neural Networks: Theory, Design, and Applications; Image and Signal Processing; and Intelligent Social Networks.