Defining Optimal Immunotherapies For Type 1 Diabetes
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Defining Optimal Immunotherapies For Type 1 Diabetes
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Author : Gregory R. Bock
language : en
Publisher: John Wiley & Sons
Release Date : 2008-07-31
Defining Optimal Immunotherapies For Type 1 Diabetes written by Gregory R. Bock and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-07-31 with Science categories.
This book is a comprehensive and up-to-date account of where we stand in immunological strategies for preventing or treating type 1 diabetes (T1D). Brings together contributions from the leaders in the arena of clinical immunotherapy, not limited to the diabetes field exclusively, in order to delineate a road-map that would lead to future clinical trials. The book integrates information from human and animal studies. The book considers T1D within the broader context of autoimmune disease. The format contains several discussions, which address specific questions and provides guidelines for future strategies and solutions for discovering a cure.
Immunotherapy Of Type 1 Diabetes
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Author : Domenico Andreani
language : en
Publisher: John Wiley & Sons
Release Date : 1989
Immunotherapy Of Type 1 Diabetes written by Domenico Andreani and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Health & Fitness categories.
Recent national, European and international diabetes meetings have seen controversial discussions on the potential benefit and also on ethical aspects of immune intervention in patients with Type 1 diabetes or in persons with a high risk of developing the disease.
Stem Cells From Hype To Real Hope
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Author : Khawaja Husnain Haider
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2018-12-17
Stem Cells From Hype To Real Hope written by Khawaja Husnain Haider and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-17 with Medical categories.
This book is a compilation of the bench experience of leading experts from various research labs involved in the cutting edge area of research. The authors describe the use of stem cells both as part of the combinatorial therapeutic intervention approach and as tools (disease model) during drug development, highlighting the shift from a conventional symptomatic treatment strategy to addressing the root cause of the disease process. The book is a continuum of the previously published book entitled "Stem Cells: from Drug to Drug Discovery" which was published in 2017.
The Value Of Bcg And Tnf In Autoimmunity
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Author : Denise Faustman
language : en
Publisher: Academic Press
Release Date : 2014-03-13
The Value Of Bcg And Tnf In Autoimmunity written by Denise Faustman and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-13 with Medical categories.
The Value of BCG and TNF in Autoimmunity provides an overview of current research and thinking related to tumor necrosis factor (TNF) induction and the use of the bacillus Calmette-Guérin (BCG) vaccine as potential treatment approaches to diverse forms of autoimmunity. BCG, commonly known as an anti-tuberculosis vaccine, is being explored in worldwide clinical trials as an approach to the treatment of certain forms of autoimmunity. The scope of research behind this therapeutic approach spans from the basic science of TNF signaling to research in diverse autoimmune disciplines, such as type 1 diabetes and multiple sclerosis. Overall, the book focuses on the lessons that can be learned from the researchers' individual experiences and data, and provides a rationale for bringing the inexpensive, generic BCG vaccine to the forefront of clinical trials in different forms of autoimmunity. Editor awarded 2005: Oprah Achievement Award," Top Health Breakthrough by a Female Scientist" Brings into one resource the international scientific literature on a unique way to treat autoimmunity Provides a different perspective on treatment approaches for certain autoimmune conditions Discusses TNF induction, rather than anti-TNF, as a therapeutic pathway for autoimmunity treatment
Diabetes Mellitus In Children
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Author : Mark A. Sperling
language : en
Publisher:
Release Date : 2005
Diabetes Mellitus In Children written by Mark A. Sperling and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Children categories.
Immune Checkpoint Inhibitors In Cancer
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Author : Fumito Ito
language : en
Publisher: Elsevier Health Sciences
Release Date : 2018-09-03
Immune Checkpoint Inhibitors In Cancer written by Fumito Ito and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-03 with Medical categories.
Get a quick, expert overview of the latest clinical information and guidelines for cancer checkpoint inhibitors and their implications for specific types of cancers. This practical title by Drs. Fumito Ito and Marc Ernstoff synthesizes the most up-to-date research and clinical guidance available on immune checkpoint inhibitors and presents this information in a compact, easy-to-digest resource. It’s an ideal concise reference for trainee and practicing medical oncologists, as well as those in research. Discusses the current understanding of how to best harness the immune system against different types of cancer at various stages. Helps you translate current research and literature into practical information for daily practice. Presents information logically organized by disease site. Covers tumor immunology and biology; toxicities associated with immune checkpoint inhibitors; and future outlooks. Consolidates today’s available information on this timely topic into one convenient resource.
Conquering Diabetes
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Author : United States. Congress. Senate. Committee on Governmental Affairs. Permanent Subcommittee on Investigations
language : en
Publisher:
Release Date : 2000
Conquering Diabetes written by United States. Congress. Senate. Committee on Governmental Affairs. Permanent Subcommittee on Investigations and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medical categories.
Of the report and recommendations of the congressionally established diabetes research working group -- Conquering diabetes -- Diabetes overview -- Diabetes statistics.
Insulin Resistance
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Author : Sudhesh Kumar
language : en
Publisher: John Wiley & Sons
Release Date : 2005-01-14
Insulin Resistance written by Sudhesh Kumar and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-01-14 with Medical categories.
Diabetes is now one of the major causes of morbidity worldwide. In many cases, the onset of diabetes is progressive, developing via a condition of insulin resistance. This book considers the development of this condition, its consequences and clinical and therapeutic aspects. The book reviews the normal biology of insulin action on glucose, lipids and proteins. It considers the pathological basis for insulin resistance in animal models and humans, and discusses the influence of heredity, dietary factors and exercise. Clinical consequences including dyslipidaemia, hypertension and polycystic ovary syndrome, and therapeutic strategies for treatment are also examined. * Provides an expert review of the phenomenon of insulin resistance * Brings together a host of recent research for the first time * Written by leading experts in biological and clinical research
Therapeutic Immunology
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Author : Terry B. Strom
language : en
Publisher: Wiley-Blackwell
Release Date : 2001-03-30
Therapeutic Immunology written by Terry B. Strom and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-03-30 with Medical categories.
Therapeutic Immunology is a comprehensive review of the clinical application of the drugs, biologic agents, and procedures used to treat immunologic diseases. It is the only reference that provides current information on antibodies, cytokines, gene and cell therapies, vaccines, and other therapeutic approaches in the managament of immune system disorders. This book will show how immunology has come of age as a clinical discipline and is now able to provide treatment strategies for many previously incurable diseases.
Cd4 Cd25 Regulatory T Cells Origin Function And Therapeutic Potential
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Author : B. Kyewski
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-01-09
Cd4 Cd25 Regulatory T Cells Origin Function And Therapeutic Potential written by B. Kyewski and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-09 with Medical categories.
The vertebrate immune system defends the organism against invading pathogens while at the same time being self-tolerant to the body’s own constituents thus preserving its integrity. Multiple mechanisms work in concert to ensure self-tolerance. Apart from purging the T cell repertoire from auto-reactive T cells via negative selection in the thymus dominant tolerance exerted by regulatory T cells plays a major role in tolerance imposition and maintenance. Among the various regulatory/suppressive cells hitherto described, CD4+CD25+ regulatory T cells (Treg) and interleukin-10 producing T regulatory 1 (Tr1) cells have been studied in most detail and are the subject of most articles in this issue. Treg, also called "natural" regulatory T cells, will be traced from their intra-thymic origin to the site of their action in peripheral lymphoid organs and tissues. The repertoire of Treg is clearly biased towards recognition of self-antigens, thereby potentially preventing autoimmune diseases such as gastritis and oophoritis. Regulatory T cells, however also control infections, allergies and tolerance to transplanted tissues and this requires their induction in the periphery under conditions which are not yet fully understood. The concept of dominant tolerance, by far not novel, will offer new insights and hopefully tools for the successful treatment of autoimmune diseases, improved cancer immunotherapy and transplant survival. The fulfillment of these high expectations will, however, require their unambiguous identification and a better understanding of their mode of action.