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Delta Opioid Receptor Pharmacology And Therapeutic Applications

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Delta Opioid Receptor Pharmacology And Therapeutic Applications

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Author : Emily M. Jutkiewicz
language : en
Publisher: Springer
Release Date : 2018-09-27

Delta Opioid Receptor Pharmacology And Therapeutic Applications written by Emily M. Jutkiewicz and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-27 with Medical categories.

This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds and therapies used to modulate the DOR system. Part 2 describes new insights into the localization and trafficking of the DOR and how ligand-directed signaling alters the fate of the receptor. Part 3 concentrates on the potential role of the DOR system in disease states, such as pain, mood, addiction, and Parkinson’s disease. Throughout the book, the DOR system as a target for drug development will be discussed.

Delta Opioid Receptor Pharmacology And Therapeutic Applications

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Author :
language : en
Publisher:
Release Date : 2018

Delta Opioid Receptor Pharmacology And Therapeutic Applications written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with MEDICAL categories.

This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds and therapies used to modulate the DOR system. Part 2 describes new insights into the localization and trafficking of the DOR and how ligand-directed signaling alters the fate of the receptor. Part 3 concentrates on the potential role of the DOR system in disease states, such as pain, mood, addiction, and Parkinson's disease. Throughout the book, the DOR system as a target for drug development will be discussed.

Opiate Receptors And Antagonists

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Author : Reginald Dean
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-03-12

Opiate Receptors And Antagonists written by Reginald Dean and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-12 with Medical categories.

Comprehensive and authoritative, Opioid Receptors and Antagonists: From Bench to Clinic offers neuroscientists, pharmacologists and interested clinicians a unique survey of the extensive and diverse research efforts currently employed with opioid antagonists to develop novel innovative drug therapies. Summarizes the present understanding of the chemistry, pharmacology and molecular biology of opioid receptors and their subtypes Highlights differences and similarities between the opioid pharmacology of animals and human Describes current and potential therapeutic areas for opioid antagonists, including substance abuse, alcohol and ingestive behaviors, behavioral disorders and other medical indications, supported by nonclinical and clinical evidence Focuses on the development of exciting and innovative drug delivery approaches that are being used with opioid antagonists for the above medical indications

Opioid Receptors Advances In Research And Application 2011 Edition

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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09

Opioid Receptors Advances In Research And Application 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Psychology categories.

Opioid Receptors: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Opioid Receptors. The editors have built Opioid Receptors: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Opioid Receptors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Opioid Receptors: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Opiate Receptors And Antagonists

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Author : Reginald Dean
language : en
Publisher: Humana Press
Release Date : 2009-05-04

Opiate Receptors And Antagonists written by Reginald Dean and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-04 with Medical categories.

Opioids And Their Receptors

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Author : Mariana Spetea
language : en
Publisher: MDPI
Release Date : 2020-12-18

Opioids And Their Receptors written by Mariana Spetea and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-18 with Medical categories.

The interest in opioids such as morphine, the prototypical opioid ligand, has been maintained through the years. The identification of endogenous opioids and their receptors (mu, delta, kappa, and nociceptin), molecular cloning, and the elucidation of the crystal structures of opioid receptors represent key milestones in opioid research. The opioid system modulates numerous pharmacological responses, with therapeutic (i.e., analgesia) and detrimental side effects (i.e., addiction). The medical use and misuse of opioids have dramatically increased, leading to the 21st century opioid crisis. This book presents recent developments in opioid drug discovery, specifically in the medicinal chemistry and pharmacology of new ligands targeting the opioid receptors as effective and safe therapeutics for human diseases. Furthermore, it draws a special attention to advancing concepts and strategies in opioid drug discovery to mitigate opioid liabilities. The diversity among the discussed topics is a testimony to the complexity of the opioid system, which results from the expression, regulation, and functional role of ligands and receptors. The array of multidisciplinary research areas illustrates the rapidly developing basic research and translational activities in opioid drug discovery. This book will serve as a useful reference while also stimulating continued research in the chemistry and pharmacology of opioids and their receptors, with the prospect of developing improved therapies for human diseases, but also improving health and quality of life in general.

The Kappa Opioid Receptor

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Author : Lee-Yuan Liu-Chen
language : en
Publisher: Springer Nature
Release Date : 2021-11-25

The Kappa Opioid Receptor written by Lee-Yuan Liu-Chen and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-25 with Medical categories.

This book covers the latest knowledge in structure, signaling, and biochemical pharmacology of KOR as well as preclinical research and clinical applications (including clinical phase studies and approved for human use) of KOR compounds. It is divided up into the three parts: Molecular aspects of KOR, Preclinical research on pharmacology of KOR agonists and antagonists in animals and KOR agonists and antagonists in clinical use and in past and present clinical trials. The chapters "Biosensors monitor ligand-selective effects at kappa opioid receptors" and "The role of dynorphin and the kappa opioid receptor in schizophrenia and major depressive disorder: a translational approach" of this book are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Opioid Receptors Advances In Research And Application 2013 Edition

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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2013-06-21

Opioid Receptors Advances In Research And Application 2013 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-21 with Science categories.

Opioid Receptors—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about kappa Opioid Receptors. The editors have built Opioid Receptors—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about kappa Opioid Receptors in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Opioid Receptors—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Opioid Receptors Advances In Research And Application 2012 Edition

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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-26

Opioid Receptors Advances In Research And Application 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-26 with Science categories.

Opioid Receptors—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Opioid Receptors. The editors have built Opioid Receptors—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Opioid Receptors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Opioid Receptors—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

The Delta Receptor

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Author : Kwen-Jen Chang
language : en
Publisher: CRC Press
Release Date : 2003-12-11

The Delta Receptor written by Kwen-Jen Chang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-12-11 with Science categories.

The Delta Receptor spans current research in delta receptor biology, pharmacology, physiology, and chemistry to identify, advance, and inspire the development of novel drug candidates. It demonstrates the potential significance and impact of the delta receptor in the therapy and treatment of medical conditions such as pain, gastrointestinal disorders, bladder dysfunction, and depression, as well as heart attack prevention. This reference examines the pathophysiological functions and mechanisms of receptor-selective drugs. Documenting key advances in the field, The Delta Receptor represents the most comprehensive and up-to-date studies on receptor applications currently available.

Delta Opioid Receptor Pharmacology And Therapeutic Applications

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