Dendritic Neurotransmitter Release
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Dendritic Neurotransmitter Release
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Author : Mike Ludwig
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-06
Dendritic Neurotransmitter Release written by Mike Ludwig and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-06 with Medical categories.
The transmission of the nervous impulse is always from the dendritic branches and the cell body to the axon or functional process. Every neuron, then, possesses a receptor apparatus, the body and the dendritic prolongations, an apparatus of emission, the axon, and the apparatus of distribution, the terminal arborization of the nerve fibers. I designated the foregoing principle: the theory of dynamic polarization (Cajal 1923). Ever since the beautiful drawings from Golgi and Cajal, we have been familiar with the organisation of neurones into dendritic, somatic and axonal compartments. Cajal proposed that these cellular compartments were specialised, resulting in his concept of ^dynamic polarisation'. He considered dendrites to be passive elements that simply transferred information from inputs to the soma. Since the discovery that dendrites of many neural populations release neuroactive substances and in doing so, alter neuronal output, it is now apparent that this theory requires qualification. This book presents recent developments in the neurophysiology of dendritic release of several chemical classes of transmitters in a number of different areas of the mammalian central nervous system. Once released from a neuron, these substances can act as neurotransmitters and/or neuromodulators, to autoregulate the original neuron, its synaptic inputs, and adjacent cells or, by volume transmission, to affect distant cells. In some systems, dendritic transmitter release is part independent of secretion from axon terminal signifying a selective control of the dendritic compartment.
Mathematical Analysis And Numerical Methods For Science And Technology Spectral Theory And Applications
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Author : Robert Dautray
language : en
Publisher: Springer Verlag
Release Date : 1990
Mathematical Analysis And Numerical Methods For Science And Technology Spectral Theory And Applications written by Robert Dautray and has been published by Springer Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Mathematics categories.
Neurotransmitter Release And Its Modulation
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Author : David A. Powis
language : en
Publisher: Cambridge University Press
Release Date : 1995-08-24
Neurotransmitter Release And Its Modulation written by David A. Powis and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-08-24 with Medical categories.
A uniquely comprehensive and integrated account of neurotransmitter modulation. Suitable for neuroscientists and non-specialists alike.
Dendritic Neurotransmitter Release
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Author : Mike Ludwig
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-06
Dendritic Neurotransmitter Release written by Mike Ludwig and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-06 with Medical categories.
The transmission of the nervous impulse is always from the dendritic branches and the cell body to the axon or functional process. Every neuron, then, possesses a receptor apparatus, the body and the dendritic prolongations, an apparatus of emission, the axon, and the apparatus of distribution, the terminal arborization of the nerve fibers. I designated the foregoing principle: the theory of dynamic polarization (Cajal 1923). Ever since the beautiful drawings from Golgi and Cajal, we have been familiar with the organisation of neurones into dendritic, somatic and axonal compartments. Cajal proposed that these cellular compartments were specialised, resulting in his concept of ^dynamic polarisation'. He considered dendrites to be passive elements that simply transferred information from inputs to the soma. Since the discovery that dendrites of many neural populations release neuroactive substances and in doing so, alter neuronal output, it is now apparent that this theory requires qualification. This book presents recent developments in the neurophysiology of dendritic release of several chemical classes of transmitters in a number of different areas of the mammalian central nervous system. Once released from a neuron, these substances can act as neurotransmitters and/or neuromodulators, to autoregulate the original neuron, its synaptic inputs, and adjacent cells or, by volume transmission, to affect distant cells. In some systems, dendritic transmitter release is part independent of secretion from axon terminal signifying a selective control of the dendritic compartment.
Dendrites
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Author : Greg Stuart
language : en
Publisher: Oxford University Press
Release Date : 2016
Dendrites written by Greg Stuart and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Medical categories.
Dendrites are complex neuronal structures that receive and integrate synaptic input from other nerve cells. They therefore play a critical role in brain function. Although dendrites were discovered over a century ago, due to the development of powerful new techniques there has been a dramatic resurgence of interest in the properties and function of these beautiful structures. This is the third edition of the first book devoted exclusively to dendrites. It contains a comprehensive survey of the current state of dendritic research across a wide range of topics, from dendritic morphology, evolution, development, and plasticity through to the electrical, biochemical and computational properties of dendrites, and finally to the key role of dendrites in brain disease. The third edition has been thoroughly revised, with each chapter updated or completely rewritten by leading experts, plus the addition of a number of new chapters. "Dendrites" will be of interest to researchers and students in neuroscience and related fields, as well as to anyone interested in how the brain works.
Neuroscience In The 21st Century
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Author : Donald W. Pfaff
language : en
Publisher: Springer
Release Date : 2016-10-27
Neuroscience In The 21st Century written by Donald W. Pfaff and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-27 with Medical categories.
Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people globally suffer from depression and 25 million people from schizophrenia; 91 million people are affected by alcohol use disorders and 15 million by drug use disorders. A more recent WHO report shows that 50 million people suffer from epilepsy and 24 million from Alzheimer’s and other dementias. Because neuroscience takes the etiology of disease—the complex interplay between biological, psychological, and sociocultural factors—as its object of inquiry, it is increasingly valuable in understanding an array of medical conditions. A recent report by the United States’ Surgeon General cites several such diseases: schizophrenia, bipolar disorder, early-onset depression, autism, attention deficit/ hyperactivity disorder, anorexia nervosa, and panic disorder, among many others. Not only is this volume a boon to those wishing to understand the future of neuroscience, it also aims to encourage the initiation of neuroscience programs in developing countries, featuring as it does an appendix full of advice on how to develop such programs. With broad coverage of both basic science and clinical issues, comprising around 150 chapters from a diversity of international authors and including complementary video components, Neuroscience in the 21st Century in its second edition serves as a comprehensive resource to students and researchers alike.
Extrasynaptic Neurotransmission As A Way Of Modulating Multiple Neuronal Functions
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Author : Francisco F. De-Miguel
language : en
Publisher: Frontiers E-books
Release Date :
Extrasynaptic Neurotransmission As A Way Of Modulating Multiple Neuronal Functions written by Francisco F. De-Miguel and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Extrasynaptic transmission is a unifying term for a wide variety of cellular processes, in which outside of synaptic terminals transmitter substances activate extrasynaptic receptors. Whereas “synaptic transmission” immediately refers to a process occurring at nerve terminals in which the arrival of a presynaptic impulse evokes exocytosis followed by a postsynaptic response within a millisecond time scale, extrasynaptic transmission has a wide diversity of ultrastructural and therefore mechanistic associated phenomena. In comparison to synaptic, extrasynaptic exocytosis may last for seconds or even minutes, thus expanding the timing of neuronal signaling. Extrasynaptic transmission has now been demonstrated in central and peripheral neurons of vertebrates and invertebrates, and involves many different types of transmitter substances than include low molecular weight transmitters (acetilcholine, GABA, glutamate, ATP, and biogenic amines) and peptides (substance P, vasopressin and others). It may occur when transmitters leak out from the synaptic cleft and activate extrasynaptic receptors in neighboring neurons or glial cells, or when axonal varicosities, dendrites or the somata release transmitters in the absence of postsynaptic counterparts. The release mechanisms also vary from one neuron type to another and from one neuronal compartment to another. In some cases, clear vesicles are apposed to the resting plasma membrane, as in presynaptic terminals. In other cases, transmitters are packed onto dense core vesicles that rest at a distance from the release sites. In between, there are multiple morphological combinations that point to complementary mechanisms in different compartments of the same neuron and some times, even in the same compartment. For example, serotonergic varicosities may combine clear and dense core vesicles in stereotyped arrays. This diversity adds complexity to the nervous system and raises many questions that are waiting for answers. Extrasynaptic transmission may be the main source of transmitter molecules causing volume transmission, however this still lacks direct demonstration. From the physiological point of view, one may ask how does the neuronal firing pattern evokes synaptic or extrasynaptic transmitter release or what are the physiological effects of these modes of transmission. From the behavioral point of view it becomes interesting to explore how circuits and therefore behaviors are modulated. Some neurological disfunctions may also be related to deficiencies in extrasynaptic transmission, however, again, direct studies are still lacking. Developmental and evolutionary biologists may also find the topic inspiring. Extrasynaptic transmission not only expands our view about how the nervous system works, but also requires a change in the way we plan our research. New technological and computational tools are now being applied to analyze intracellular and extracellular transmitter mobilizations or long term changes of neuronal circuits. New definitions and mechanisms may become visible. In the meanwhile, this seems to be a good moment for a first common effort to analyze and discuss extrasynaptic transmission in different systems and from different perspectives.
Release Of Chemical Transmitters From Cell Bodies And Dendrites Of Nerve Cells
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Author : Francisco Rafael Fernández de Miguel
language : en
Publisher:
Release Date : 2015
Release Of Chemical Transmitters From Cell Bodies And Dendrites Of Nerve Cells written by Francisco Rafael Fernández de Miguel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Cell interaction categories.
Dendrites
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Author : Greg Stuart
language : en
Publisher: Oxford University Press, USA
Release Date : 2007
Dendrites written by Greg Stuart and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
Dendrites form the major receiving part of neurons. This text presents a survey of knowledge on dendrites, from their morphology and development, through to their electrical chemical, and computational properties.
Foundations Of Neuroscience
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Author : Casey Henley
language : en
Publisher:
Release Date : 2021
Foundations Of Neuroscience written by Casey Henley and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Biology categories.