Determination Of Some Carcinogenic Contaminants In Food
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Determination Of Some Carcinogenic Contaminants In Food
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Author : Sergei Yurchenko
language : en
Publisher:
Release Date : 2006
Determination Of Some Carcinogenic Contaminants In Food written by Sergei Yurchenko and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Carcinogens categories.
Safety Evaluation Of Certain Contaminants In Food
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Author : Joint FAO/WHO Expert Committee on Food Additives. Meeting
language : en
Publisher: Food & Agriculture Org.
Release Date : 2006
Safety Evaluation Of Certain Contaminants In Food written by Joint FAO/WHO Expert Committee on Food Additives. Meeting and has been published by Food & Agriculture Org. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Technology & Engineering categories.
Safety Evaluation Of Certain Contaminants In Food
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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2023-07-14
Safety Evaluation Of Certain Contaminants In Food written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-14 with Medical categories.
Food Contaminants And Residue Analysis
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Author : Yolanda Picó
language : en
Publisher: Elsevier
Release Date : 2008-09-10
Food Contaminants And Residue Analysis written by Yolanda Picó and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-10 with Science categories.
Food Contaminants and Residue Analysis treats different aspects of the analysis of contaminants and residues in food and highlights some current concerns facing this field. The content is initiated by an overview on food safety, the objectives and importance of determining contaminants and residues in food, and the problems and challenges associated to these analyses. This is followed by full details of relevant EU and USA regulations. Topics, such as conventional chromatographic methods, accommodating cleanup, and preparing substances for further instrumental analysis, are encompassed with new analytical techniques that have been developed, significantly, over the past few years, like solid phase microextraction, liquid chromatography-mass spectrometry, immunoassays, and biosensors. A wide range of toxic contaminants and residues, from pesticides to mycotoxins or dioxins are examined, including polychlorinated biphenyls, polycyclic aromatic hydrocarbons, N-nitrosamines, heterocyclic amines, acrylamide, semicarbazide, phthalates and food packing migrating substances. This book can be a practical resource that offers ideas on how to choose the most effective techniques for determining these compounds as well as on how to solve problems or to provide relevant information. Logically structured and with numerous examples, Food Contaminants and Residue Analysis will be valuable a reference and training guide for postgraduate students, as well as a practical tool for a wide range of experts: biologists, biochemists, microbiologists, food chemists, toxicologists, chemists, agronomists, hygienists, and everybody who needs to use the analytical techniques for evaluating food safety.
Establishment Of Analytical Methods For The Determination Of New Foodprocessed Contaminants
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Author : Mohammed-Soubhi Altaki
language : en
Publisher:
Release Date : 2017
Establishment Of Analytical Methods For The Determination Of New Foodprocessed Contaminants written by Mohammed-Soubhi Altaki and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
The development of sensitive analytical methods has allowed identifying non- nutrient chemicals in food that may affect the human health and are recognised as food chemical contaminants. Some of these compounds are originated from food processing and several studies have demonstrated that can induce tumours in animals. Process- induced food carcinogens are defined as those undesirable chemicals unintentionally present in food as a result of processing and/or preparation of the raw material. The discovery of acrylamide in processed carbohydrate rich food in 2002 sparked renewed interest on some other known food carcinogens such as volatile N-nitrosamines (VNAs) and has also led to the discovery of some others that were previously unknown like furan. Furan and volatile N-nitrosamines (VNAs) are induced food toxicants and due to their potential harmful effects on human health, they have been classified as probable and/or possible carcinogens to humans by the International Agency for Research on Cancer (IARC). At present, food processing technologies able to prevent their formation are not available. To guarantee food safety, identification and quantification of food contaminants as well as the evaluation of their occurrence and risk assessment are needed. An indispensable prerequisite to fulfil these objectives is to have available reliable analytical methodologies. The analysis of furan and volatile N-nitrosamines is challenging due to their physicochemical properties, relatively low concentration levels and the complexity of the food matrices and therefore, there is interest to explore new analytical methodologies able to enhance sensitivity, selectivity, adaptability and also to meet the criteria of European Commission (2002/657/EC) regarding the validation and establishing the performance of analytical methods. In this context, this thesis was conducted to study furan and volatile N- nitrosamines as process-induced food toxicants from the development of analytical methodologies to the evaluation of their presence in food and risk assessment estimation for Spanish population. A fully automated headspace solid-phase microextraction (HS- SPME) gas chromatography coupled to ion-trap mass spectrometry (GC-ITMS) methods to evaluate the presence of these contaminants in food products and to estimate the real exposure of the population to these compounds were established. Parameters affecting the HS-SPME performance including extraction and desorption conditions were experimentally optimised in order to obtain the maximum extraction efficiencies. In addition, GC-ITMS methods using electron ionization and full scan MS mode for furan analysis and selected reaction monitoring tandem mass spectrometry with chemical ionization (CI-IT MS/MS) for VNAs analysis were developed. The experimental results are presented in three scientific papers, two devoted to furan determination and one to the analysis of volatile N-nitrosamines. The applicability of both HS-SPME-GC-MS methods for the determination of furan and VNAs has been demonstrated analysing several selected foods commercialised in Spain. Furan was detected in all samples at concentrations, being baby food and coffee the products with the highest furan content. In contrast, VNAs were not detected in any of the analysed beer samples at concentrations levels above limits of quantification, and the presence of VNAs (NDMA and NPYR) were only found in 3 out of 18 processed meat product samples analysed indicating the effectiveness of the measures adopted by the manufactures to avoid the formation of VNAs. Therefore, a survey on furan content in coffee brews and baby foods was conducted while this study was not performed for VNA because of the low frequency and levels found in the samples analysed in this thesis. The presence of furan in coffee and baby food categories constitutes a potential risk for human health because they contain high furan content and are highly consumed. The evaluation of furan levels found in these food products are included in two scientific articles. In addition, the effect food preparation, heating and handling, on furan content and an estimation of risk assessment of furan intake from food consumption are also included.
Carcinogens And Anticarcinogens In The Human Diet
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 1996-02-12
Carcinogens And Anticarcinogens In The Human Diet written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-02-12 with Nature categories.
Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.
Some Chemicals Present In Industrial And Consumer Products Food And Drinking Water
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Author : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
language : en
Publisher: IARC Monographs on the Evaluat
Release Date : 2013
Some Chemicals Present In Industrial And Consumer Products Food And Drinking Water written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and has been published by IARC Monographs on the Evaluat this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Medical categories.
This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.
Diet Nutrition And Cancer
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Author : National Research Council
language : en
Publisher: Legare Street Press
Release Date : 2022-10-27
Diet Nutrition And Cancer written by National Research Council and has been published by Legare Street Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-27 with History categories.
This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Diet Nutrition And Cancer
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Author : National Research Council (U.S.). Committee on Diet, Nutrition, and Cancer
language : en
Publisher:
Release Date : 1982
Diet Nutrition And Cancer written by National Research Council (U.S.). Committee on Diet, Nutrition, and Cancer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Cancer categories.
How Tobacco Smoke Causes Disease
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Author : United States. Public Health Service. Office of the Surgeon General
language : en
Publisher:
Release Date : 2010
How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Government publications categories.
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.