Determination Of The Transition State Structures And Mechanisms Of Enzymatic And Nonenzymatic Reactions Through Kinetic Isotope Effects
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Determination Of The Transition State Structures And Mechanisms Of Enzymatic And Nonenzymatic Reactions Through Kinetic Isotope Effects
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Author : Barbara Gerratana
language : en
Publisher:
Release Date : 2001
Determination Of The Transition State Structures And Mechanisms Of Enzymatic And Nonenzymatic Reactions Through Kinetic Isotope Effects written by Barbara Gerratana and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.
Enzyme Mechanism From Isotope Effects
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Author : Paul F. Cook
language : en
Publisher: CRC Press
Release Date : 1991-09-20
Enzyme Mechanism From Isotope Effects written by Paul F. Cook and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-09-20 with Medical categories.
Isotope effects have become one of the most powerful tools available to the enzymologist for probing enzymic mechanisms. Enzyme Mechanism from Isotope Effects presents the basic theory underlying isotope effects, including the latest findings on proton tunneling and coupled atomic notions. Specific theoretical applications are emphasized in regard to the types of information that can be obtained using isotope effects. The book also examines recent theoretical treatments of the product dependence of deuterium isotope effects, multiple isotope effects and isotope effects on intermediate partitioning. Other topics include a complete discussion of methods for measuring isotope effects, including a detailed description of the use of the isotope ratio mass spectrometer to obtain isotope effects, and a review of the literature regarding mechanistic information obtained from isotope effects for individual classes of enzyme-catalyzed reactions. Enzyme Mechanism from Isotope Effects is an excellent reference source for investigators using isotope effects in their research. The book is also valuable for reference libraries and instructors teaching courses in enzyme mechanism.
Advances In Physical Organic Chemistry
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Author : John P. Richard
language : en
Publisher: Gulf Professional Publishing
Release Date : 2002-12-31
Advances In Physical Organic Chemistry written by John P. Richard and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-12-31 with Science categories.
Advances in Physical Organic Chemistry provides the chemical community with authoritative and critical assessments of the many aspects of physical organic chemistry. The field is a fast developing one, with results and methodologies finding application from biology to solid state physics. This latest volume deals comprehensively with investigations that can be traced back to the birth of the field but which are still proving critical to the understanding of the stability of organic molecules and the mechanisms for their reactions. Volume 37 of this hugely successful Advances in Physical Organic Chemistry series Comprehensive review articles covering various topics of interest within the physical organic chemistry field
Organic Chemistry
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Author : Pierre Vogel
language : en
Publisher: John Wiley & Sons
Release Date : 2019-08-08
Organic Chemistry written by Pierre Vogel and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-08 with Science categories.
Provides the background, tools, and models required to understand organic synthesis and plan chemical reactions more efficiently Knowledge of physical chemistry is essential for achieving successful chemical reactions in organic chemistry. Chemists must be competent in a range of areas to understand organic synthesis. Organic Chemistry provides the methods, models, and tools necessary to fully comprehend organic reactions. Written by two internationally recognized experts in the field, this much-needed textbook fills a gap in current literature on physical organic chemistry. Rigorous yet straightforward chapters first examine chemical equilibria, thermodynamics, reaction rates and mechanisms, and molecular orbital theory, providing readers with a strong foundation in physical organic chemistry. Subsequent chapters demonstrate various reactions involving organic, organometallic, and biochemical reactants and catalysts. Throughout the text, numerous questions and exercises, over 800 in total, help readers strengthen their comprehension of the subject and highlight key points of learning. The companion Organic Chemistry Workbook contains complete references and answers to every question in this text. A much-needed resource for students and working chemists alike, this text: -Presents models that establish if a reaction is possible, estimate how long it will take, and determine its properties -Describes reactions with broad practical value in synthesis and biology, such as C-C-coupling reactions, pericyclic reactions, and catalytic reactions -Enables readers to plan chemical reactions more efficiently -Features clear illustrations, figures, and tables -With a Foreword by Nobel Prize Laureate Robert H. Grubbs Organic Chemistry: Theory, Reactivity, and Mechanisms in Modern Synthesis is an ideal textbook for students and instructors of chemistry, and a valuable work of reference for organic chemists, physical chemists, and chemical engineers.
Isotope Effects In Chemistry And Biology
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Author : Amnon Kohen
language : en
Publisher: CRC Press
Release Date : 2005-11-01
Isotope Effects In Chemistry And Biology written by Amnon Kohen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-01 with Medical categories.
The field of isotope effects has expanded exponentially in the last decade, and researchers are finding isotopes increasingly useful in their studies. Bringing literature on the subject up to date, Isotope Effects in Chemistry and Biology covers current principles, methods, and a broad range of applications of isotope effects in the physical, biolo
Enzyme Kinetics And Mechanism
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Author : Paul F. Cook
language : en
Publisher: Garland Science
Release Date : 2007-03-06
Enzyme Kinetics And Mechanism written by Paul F. Cook and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-06 with Medical categories.
Enzyme Kinetics and Mechanism is a comprehensive textbook on steady-state enzyme kinetics. Organized according to the experimental process, the text covers kinetic mechanism, relative rates of steps along the reaction pathway, and chemical mechanism—including acid-base chemistry and transition state structure. Practical examples taken from the literature demonstrate theory throughout. The book also features numerous general experimental protocols and how-to explanations for interpreting kinetic data. Written in clear, accessible language, the book will enable graduate students well-versed in biochemistry to understand and describe data at the fundamental level. Enzymologists and molecular biologists will find the text a useful reference.
Measurement And Analysis Of Kinetic Isotope Effects
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Author :
language : en
Publisher: Academic Press
Release Date : 2017-09-12
Measurement And Analysis Of Kinetic Isotope Effects written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-12 with Medical categories.
Experimental Analysis of Enzyme Mechanism Using Isotope Effects, Volume 596, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this comprehensive update include Measurement of enzyme binding isotope effects, Chemical ligation and isotope labeling to locate dynamic effects, Measurement of heavy enzyme isotope effects, Extracting kinetic isotope effects from a global analysis of reaction progress curves, KIE of metabolic flux and enzymes, Solvent and Primary KIE on Flavin Enzymes, and The Rapid Determination of Primary Deuterium Isotope Effects on Enzyme-Catalyzed Proton Transfer at Carbon in 50/50 HOH/DOD. Readers who are interested in applying or understanding this research will find useful methods currently used for measuring isotope effects on solution and enzyme reactions. Written by pioneers of modern isotope effect research Is the only collection of modern kinetic isotope effect methods currently available
Organic Reaction Mechanisms 1988
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Author : A. C. Knipe
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-30
Organic Reaction Mechanisms 1988 written by A. C. Knipe and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-30 with Science categories.
The only book series to summarize the latest progress on organic reaction mechanisms, Organic Reaction Mechanisms, 1988 surveys the development in understanding of the main classes of organic reaction mechanisms reported in the primary scientific literature in 1988. The 24th annual volume in this highly successful series highlights mechanisms of stereo-specific reactions. Reviews are compiled by a team of experienced editors and authors, allowing advanced undergraduates, graduate students, postdocs, and chemists to rely on the volume's continuing quality of selection and presentation.
Progress In Nucleic Acid Research And Molecular Biology
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Author : Kivie Moldave
language : en
Publisher: Elsevier
Release Date : 2003-09-15
Progress In Nucleic Acid Research And Molecular Biology written by Kivie Moldave and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-15 with Science categories.
Nucleic acids are the fundamental building blocks of DNA and RNA and are found in virtually every living cell. Molecular biology is a branch of science that studies the physicochemical properties of molecules in a cell, including nucleic acids, proteins, and enzymes. Increased understanding of nucleic acids and their role in molecular biology will further many of the biological sciences including genetics, biochemistry, and cell biology. Progress in Nucleic Acid Research and Molecular Biology is intended to bring to light the most recent advances in these overlapping disciplines with a timely compilation of reviews comprising each volume. * Provides a forum for discussion of new discoveries, approaches and ideas in molecular biology* Includes contributions from the leaders in the field* Has abundant references
Use Of Isotope Effects To Determine Enzymatic And Nonenzymatic Mechanisms
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Author : Mark Alan Rishavy
language : en
Publisher:
Release Date : 2000
Use Of Isotope Effects To Determine Enzymatic And Nonenzymatic Mechanisms written by Mark Alan Rishavy and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with categories.