Development Of Methods For Directed And Structured Immobilization Of Biomolecules
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Development Of Methods For Directed And Structured Immobilization Of Biomolecules
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Author : Björn Waterkotte
language : en
Publisher:
Release Date : 2013
Development Of Methods For Directed And Structured Immobilization Of Biomolecules written by Björn Waterkotte and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.
Development Of Methods For Directed And Structured Immobilization Of Biomolecules
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Author : Björn Waterkotte
language : en
Publisher: Cuvillier Verlag
Release Date : 2013-11-07
Development Of Methods For Directed And Structured Immobilization Of Biomolecules written by Björn Waterkotte and has been published by Cuvillier Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-07 with Science categories.
Surface immobilized molecules play a crucial role in applied as well as in basic research. They can be found in DNA or protein-array as well as in cell-migration or biochemical interaction experiments. Especially for proteins the immobilization can critically affect molecule accessibility and activity. In this work two essential aspects of protein immobilization were investigated: the identification of suitable surface functionalization by two array approaches and the generation of laterally structured gray scale protein patterns by projection lithography. In proof-of-concept experiments a new strategy to create an array of different, neighboring functionalizations on the same surface was successfully tested. In "mechanical protection" inert plungers were applied to protect distinct surface areas from the surface functionalization reagents and allowed a selective modification of individual regions in serial reactions. In a particle based alternative approach a high spot density surface array was fabricated using functionalized, polyvinyl acetate, melamine and silicon oxide-based particles. The in situ encoded bead-based array (IEBA) allowed the study of immobilization conditions and the effect of protein adhesion. For the reliable and fast analysis of array-images with several thousand individual particles a custom open-source evaluation software was developed. To create protein patterns a custom-built projection lithography device was utilized to generate high definition protein patterns. Patterning conditions were optimized with respect to deposition speed and signal to noise ratio while retaining a biocompatible process flow. The established technology provides protein patterns with great control over the deposited surface density, patterns were transferred within seconds to minutes to functionalized glass slides. To obtain three-dimensional, surface-functionalized surfaces this approach was transferred to thin polymer films. The substrates were demonstrated to be biocompatible with mouse fibroblasts. These surfaces allow a novel level of control addressing both the chemical surrounding and the shape of a cell microenvironment.
National Marine Pollution Program
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Author :
language : en
Publisher:
Release Date : 1986
National Marine Pollution Program written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Marine pollution categories.
Surface Modification Of Biopolymers
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Author : Vijay Kumar Thakur
language : en
Publisher: John Wiley & Sons
Release Date : 2015-05-26
Surface Modification Of Biopolymers written by Vijay Kumar Thakur and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-26 with Technology & Engineering categories.
This book addresses surface modification techniques, which are critical for tailoring and broadening the applications of naturally occurring biopolymers. Biopolymers represent a sustainable solution to the need for new materials in the auto, waste removal, biomedical device, building material, defense, and paper industries. Features: First comprehensive summary of biopolymer modification methods to enhance compatibility, flexibility, enhanced physicochemical properties, thermal stability, impact response, and rigidity, among others Address of a green, eco-friendly materials that is increasing in use, underscoring the roles of material scientists in the future of new "green" bioolymer material use Coverage applications in automotive development, hazardous waste removal, biomedical engineering, pulp and paper industries, development of new building materials, and defense-related technologies Facilitation of technology transfer
Zinc Oxide Nanostructures Synthesis And Characterization
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Author : Sotirios Baskoutas
language : en
Publisher: MDPI
Release Date : 2018-12-04
Zinc Oxide Nanostructures Synthesis And Characterization written by Sotirios Baskoutas and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-04 with Electronic books categories.
This book is a printed edition of the Special Issue "Zinc Oxide Nanostructures: Synthesis and Characterization" that was published in Materials
Summary Of Federal Programs And Projects
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Author : United States. National Ocean Pollution Program Office
language : en
Publisher:
Release Date : 1991
Summary Of Federal Programs And Projects written by United States. National Ocean Pollution Program Office and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Marine pollution categories.
Handbook Of Nanostructured Materials And Nanotechnology Five Volume Set
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Author : Hari Singh Nalwa
language : en
Publisher: Academic Press
Release Date : 1999-10-29
Handbook Of Nanostructured Materials And Nanotechnology Five Volume Set written by Hari Singh Nalwa and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-10-29 with Science categories.
Nanostructured materials is one of the hottest and fastest growing areas in today's materials science field, along with the related field of solid state physics. Nanostructured materials and their based technologies have opened up exciting new possibilites for future applications in a number of areas including aerospace, automotive, x-ray technology, batteries, sensors, color imaging, printing, computer chips, medical implants, pharmacy, and cosmetics. The ability to change properties on the atomic level promises a revolution in many realms of science and technology. Thus, this book details the high level of activity and significant findings are available for those involved in research and development in the field. It also covers industrial findings and corporate support. This five-volume set summarizes fundamentals of nano-science in a comprehensive way. The contributors enlisted by the editor are at elite institutions worldwide. Key Features * Provides comprehensive coverage of the dominant technology of the 21st century * Written by 127 authors from 16 countries, making this truly international * First and only reference to cover all aspects of nanostructured materials and nanotechnology
9th International Conference On The Development Of Biomedical Engineering In Vietnam
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Author : Van Toi Vo
language : en
Publisher: Springer Nature
Release Date : 2023-11-19
9th International Conference On The Development Of Biomedical Engineering In Vietnam written by Van Toi Vo and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-19 with Technology & Engineering categories.
This book presents cutting-edge research and developments in the field of biomedical engineering, with a special emphasis on results achieved in Vietnam and neighboring low- and middle-income countries. Covering both fundamental and applied research, and focusing on the theme of “Translational Healthcare Technology from Advanced to Low and Middle Income Countries in the Era of Covid and Digital Transformation”, it reports on the design, fabrication, and application of low-cost and portable medical devices, biosensors, and microfluidic devices, on improved methods for biological data acquisition and analysis, on nanoparticles for biological applications, and on new achievements in biomechanics, tissue engineering, and regeneration. It describes the developments of molecular and cellular biology techniques, neuroengineering techniques, and statistical and computational methods, including artificial intelligence, for biomedical applications. It also discusses strategies to address some relevant issues in biomedical education and entrepreneurship. Gathering the proceedings of the 9th International Conference on The Development of Biomedical Engineering in Vietnam, BME 9, held on December 27-29, 2022, in Ho Chi Minh, Vietnam, the book offers important answers to current challenges in the field and a source of inspiration for scientists, engineers, and researchers with various backgrounds working in different research institutes, companies, and countries.
Polymeric Biomaterials Structure And Function
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Author : Severian Dumitriu
language : en
Publisher: CRC Press
Release Date : 2013
Polymeric Biomaterials Structure And Function written by Severian Dumitriu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Medical categories.
The third edition of a bestseller, this comprehensive reference presents the latest polymer developments and most up-to-date applications of polymeric biomaterials in medicine. Expanded into two volumes, the first volume covers the structure and properties of synthetic and natural polymers as well as bioresorbable hybrid membranes, drug delivery systems, cell bioassay systems, and electrospinning for regenerative medicine. This substantially larger resource includes state-of-the-art research and successful breakthroughs in applications that have occurred in the last ten years.
Handbook Of Immunoassay Technologies
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Author : Sandeep K. Vashist
language : en
Publisher: Academic Press
Release Date : 2018-01-02
Handbook Of Immunoassay Technologies written by Sandeep K. Vashist and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-02 with Medical categories.
Handbook of Immunoassay Technologies: Approaches, Performances, and Applications unravels the role of immunoassays in the biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, ranging from the conventional enzyme-linked immunosorbent assays, to the smartphone-based point-of-care formats. The advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, device miniaturization and interfacing, and emerging smart system technologies equipped with personalized mobile healthcare tools are paving the way to next-generation immunoassays, and are all discussed in this comprehensive text. Immunoassays play a prominent role in clinical diagnostics as they are the eyes of healthcare professionals, helping them make informed clinical decisions via confirmed disease diagnosis, and thus enabling favorable health outcomes. The faster and reliable diagnosis of infections will further control their spread to uninfected persons. Similarly, immunoassays play a prominent role in veterinary diagnostics, food analysis, environmental monitoring, defense and security, and other bioanalytical settings. Therefore, they enable the detection of a plethora of analytes, which includes disease biomarkers, pathogens, drug impurities, environmental contaminants, allergens, food adulterants, drugs of abuse and various biomolecules. Provides a valuable increase of understanding of cellular and biomedical functions Gives the most updated resource in the field of immunoassays, providing the comprehensive details of various types of immunoassays that need to be performed in healthcare, and in industrial, environmental and other biochemical settings Discusses all multifarious aspects of immunoassays Describes the immunoassay formats, along with their principle of operation, characteristics, pros and cons, and potential biochemical and bioanalytical applications Provides extensive knowledge and guided insights as detailed by experienced, renowned experts and key opinion makers in the field of immunoassays