Development Of New Synthetic Approaches Towards The Anthraquinone Xanthone Heterodimeric Structure Of Beticolin 0
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Development Of New Synthetic Approaches Towards The Anthraquinone Xanthone Heterodimeric Structure Of Beticolin 0
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Author : Janina Beck
language : en
Publisher: Logos Verlag Berlin GmbH
Release Date : 2020-09-15
Development Of New Synthetic Approaches Towards The Anthraquinone Xanthone Heterodimeric Structure Of Beticolin 0 written by Janina Beck and has been published by Logos Verlag Berlin GmbH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-15 with Science categories.
Mycotoxins are fungal secondary metabolites exhibiting adverse effects on humans, animals as well as crops, resulting in diseases and economic loss. Beticolins are mycotoxins produced by the fungus Cercospora beticola which is responsible for cercosporiosis, commonly known as leaf spot disease, causing heavy damages to crops worldwide. In order to study the mechanism of action of these biologically active compounds, this thesis aimed at the development of synthetic approaches towards the highly complex polycyclic scaffold of beticolins. Beticolins consist of a chlorinated tetrahydroxanthone linked to an anthraquinone subunit via a unique bicyclo[3.2.2]nonane ring system. A facile route towards naphthoquinone derivatives and subsequent Diels-Alder cycloadditions with functionalized dienes afforded a highly functionalized anthraquinone subunit of beticolin 0. For the installation of a tetrahydroxanthone subunit, a synthetic route was elaborated. With the obtained anthraquinone derivatives intramolecular couplings were performed under different conditions, to facilitate the construction of the bicyclo[3.2.2]nonane ring system. The formation of the desired scaffold turned out to be challenging, however a variety of novel bicyclo[3.3.1]systems was obtained, representing interesting scaffolds. During a research stay at the University of Copenhagen, the functionalization of helical beta-peptoids was examined. Peptidomimetics adopting three-dimensional structures with well-defined display of functional groups while being resistant to proteolysis, are of interest for the development of foldamers with a desired function.
Bioprospecting Of Multi Tasking Fungi For Therapeutic Applications
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Author : Kiran Babu Uppuluri
language : en
Publisher: Springer Nature
Release Date : 2025-03-30
Bioprospecting Of Multi Tasking Fungi For Therapeutic Applications written by Kiran Babu Uppuluri and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-30 with Science categories.
This book covers the multi-tasking nature of fungi for therapeutic applications. It emphasizes the simultaneous metabolic activities and functions of fungi for producing enzyme inhibitors, therapeutic molecules and other biomedical utilities like polymers, nano-composites and biosensors. The fungi are involved in the production of many therapeutically-potent secondary metabolites and polymers. The recent research on fungal bioprospecting is more focused on sustainable solutions for diverse industries and markets for the circular economy. This book also offers current and future research perspectives of fungal bioprospecting. The potential of fungi to act as a bioresource for antimicrobial, antiviral, anticancer, antiprotozoal and antituberculosis compounds has also been discussed. This book is a reference material for undergraduate students for gaining in-depth knowledge on fungal bioprospecting, particularly fungi's multi-tasking nature.
Fungal Pigments
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Author : Laurent Dufossé
language : en
Publisher: MDPI
Release Date : 2018-03-23
Fungal Pigments written by Laurent Dufossé and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-23 with Science categories.
This book is a printed edition of the Special Issue "Fungal Pigments" that was published in JoF
The Norman Admiralty
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Author : Francesco Carbonaro
language : en
Publisher: Logos Verlag Berlin GmbH
Release Date : 2021-05-06
The Norman Admiralty written by Francesco Carbonaro and has been published by Logos Verlag Berlin GmbH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-06 with History categories.
What was the real power of the Norman admirals? In what way did they practise their authority? This study on the Norman admiralty in Sicily focuses on the development of this office as it changes from an office to a title with increasing and increadible prestige in the years from the second half of the 11th century to the end of the 12th century. The admiral was an officer who worked in the royal palace for the royal authority as prime minister and was fundamental in orchestrating cultural activities. However, the admirals also established their power in fields separate to those of their position. The position of admiral was a unicum in Medieval Europe since no other political institution had a similar figure and his contribution was crucial for the development of the Norman kingdom in Sicily. The intention of this work is to study the sphere of competences of the admirality and to give a global and definitive view of the impact of the Norman admirals between the second half of the 11th century and the end of the 12th.
Oxygen Storage Dominated Three Way Catalyst Modeling
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Author : Jeremias Bickel
language : en
Publisher: Logos Verlag Berlin GmbH
Release Date : 2022-01-20
Oxygen Storage Dominated Three Way Catalyst Modeling written by Jeremias Bickel and has been published by Logos Verlag Berlin GmbH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-20 with Technology & Engineering categories.
The key to achieve optimal emission performance of a modern three-way catalyst (TWC) under transient engine operating conditions is to maintain an optimal oxidation state of the oxygen storage material inside the washcoat of the catalyst. This work demonstrates how simplified kinetic models can be developed that allow for accurately predicting the oxygen storage level under dynamic operation.