Development Of Quantitative Fast Imaging With Steady State Free Precession Fisp Techniques For High Field Preclinical Magnetic Resonance Imaging
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Metabolic And Vascular Imaging Biomarkers For Brain Aging And Alzheimer S Disease
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Author : Ai-Ling Lin
language : en
Publisher: Frontiers Media SA
Release Date : 2020-08-10
Metabolic And Vascular Imaging Biomarkers For Brain Aging And Alzheimer S Disease written by Ai-Ling Lin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-10 with Science categories.
Fast Quantitative Magnetic Resonance Imaging
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Author : Guido Buonincontri
language : en
Publisher: Springer Nature
Release Date : 2022-05-31
Fast Quantitative Magnetic Resonance Imaging written by Guido Buonincontri and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-31 with Technology & Engineering categories.
Among medical imaging modalities, magnetic resonance imaging (MRI) stands out for its excellent soft-tissue contrast, anatomical detail, and high sensitivity for disease detection. However, as proven by the continuous and vast effort to develop new MRI techniques, limitations and open challenges remain. The primary source of contrast in MRI images are the various relaxation parameters associated with the nuclear magnetic resonance (NMR) phenomena upon which MRI is based. Although it is possible to quantify these relaxation parameters (qMRI) they are rarely used in the clinic, and radiological interpretation of images is primarily based upon images that are relaxation time weighted. The clinical adoption of qMRI is mainly limited by the long acquisition times required to quantify each relaxation parameter as well as questions around their accuracy and reliability. More specifically, the main limitations of qMRI methods have been the difficulty in dealing with the high inter-parameter correlations and a high sensitivity to MRI system imperfections. Recently, new methods for rapid qMRI have been proposed. The multi-parametric models at the heart of these techniques have the main advantage of accounting for the correlations between the parameters of interest as well as system imperfections. This holistic view on the MR signal makes it possible to regress many individual parameters at once, potentially with a higher accuracy. Novel, accurate techniques promise a fast estimation of relevant MRI quantities, including but not limited to longitudinal (T1) and transverse (T2) relaxation times. Among these emerging methods, MR Fingerprinting (MRF), synthetic MR (syMRI or MAGIC), and T1‒T2 Shuffling are making their way into the clinical world at a very fast pace. However, the main underlying assumptions and algorithms used are sometimes different from those found in the conventional MRI literature, and can be elusive at times. In this book, we take the opportunity to study and describe the main assumptions, theoretical background, and methods that are the basis of these emerging techniques. Quantitative transient state imaging provides an incredible, transformative opportunity for MRI. There is huge potential to further extend the physics, in conjunction with the underlying physiology, toward a better theoretical description of the underlying models, their application, and evaluation to improve the assessment of disease and treatment efficacy.
Specialty Imaging Temporomandibular Joint And Sleep Disordered Breathing E Book
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Author : Dania F Tamimi
language : en
Publisher: Elsevier Health Sciences
Release Date : 2023-04-08
Specialty Imaging Temporomandibular Joint And Sleep Disordered Breathing E Book written by Dania F Tamimi and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-08 with Medical categories.
Meticulously updated by board-certified oral and maxillofacial radiologist, Dr. Dania Tamimi and her team of sub-specialty experts, Specialty Imaging: Temporomandibular Joint and Sleep-Disordered Breathing, second edition, is a comprehensive reference ideal for anyone involved with TMJ imaging or SDB, including oral and maxillofacial radiologists and surgeons, TMJ/craniofacial pain specialists, sleep medicine specialists, head and neck radiologists, and otolaryngologists. This detailed, beautifully illustrated volume covers recent advances in the diagnosis and treatment of both the TMJ and SDB, including how related structures are affected. Employing a multifaceted, multispecialty approach, the clinical perspectives and imaging expertise of today’s research specialists are brought together in a single, image-rich, easy-to-read text. Reflects the current emphasis on holistic diagnosis and treatment not just of the TMJ but of all related structures that can be adversely affected by any TMJ dysfunction Examines a variety of presenting clinical signs or symptoms, discusses imaging strategies and the associated conditions revealed by imaging, and helps you develop differential diagnoses Provides current, detailed information on the relationship between TMJ disorders and SDB, how imaging shows the correlation between the two, and risk factors for SDB Includes upper respiratory tract diagnoses, with multiple subsections on the nasal cavity, paranasal sinuses, nasopharynx, oropharynx, and hypopharynx, each with multiple new chapters Features new chapters on ultrasonography of the TMJ and upper respiratory tract, new content on 3D and 4D modeling and surface rendering, a new section on imaging of upper respiratory tract procedures, and new content detailing the tie-in between occlusion and SDB Includes an expanded Modalities section that includes new chapters on formulating a TMJ/upper respiratory tract report; plain film imaging of the TMJ and upper respiratory tract; CBCT analysis of the upper respiratory tract; dynamic MR of the TMJ and upper respiratory tract, and ultrasound of the TMJ Covers the role that TMJ plays in facial growth and development, stomatognathic system function, and how TMJ abnormalities change the dimensions of the facial skeleton and surrounding structures Contains over 5,000 print and online-only images (more than 300 are new), including radiologic images, full-color medical illustrations, and histologic and gross pathology photographs Reflects updates to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC-TMD)—the major clinical classification method and a key tool to assess/diagnose TMJ issues and facilitate communication for consultants, referrals, and prognoses
Preclinical Mri Of The Kidney
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Author : Andreas Pohlmann
language : en
Publisher: Humana
Release Date : 2022-02-19
Preclinical Mri Of The Kidney written by Andreas Pohlmann and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-19 with categories.
Preface... Table of Contents... Contributing Authors... Part I Introduction 1. Recommendations for Preclinical Renal MRI: A Comprehensive Open-Access Protocol Collection to Improve Training, Reproducibility, and Comparability of Studies Andreas Pohlmann, Susan J. Back, Andrea Fekete, Iris Friedli, Stefanie Hectors, Neil Peter Jerome, Min-Chi Ku, Dario Livio Longo, Martin Meier, Jason M. Millward, João S. Periquito, Erdmann Seeliger, Suraj D. Serai, Sonia Waiczies, Steven Sourbron, Christoffer Laustsen, and Thoralf Niendorf Part II Animal Models, Preparation, Monitoring, and Physiological Interventions 2. Animal Models of Renal Pathophysiology and Disease Adam Hosszu, Tamas Kaucsar, Erdmann Seeliger, and Andrea Fekete 3. Preparation and Monitoring of Small Animals in Renal MRI Tamas Kaucsar, Adam Hosszu, Erdmann Seeliger, Henning M. Reimann, and Andrea Fekete 4. Reversible (Patho-)Physiologically Relevant Test Interventions: Rationale and Examples Kathleen Cantow, Mechthild Ladwig-Wiegard, Bert Flemming, Andrea Fekete, Adam Hosszu, Erdmann Seeliger 5. Preparation of Ex Vivo Rodent Phantoms for Developing, Testing, and Training MR Imaging of the Kidney and Other Organs Jason M. Millward, João S. Periquito, Paula Ramos Delgado, Christian Prinz, Thoralf Niendorf, and Sonia Waiczies Part III Basic Concepts of Measurement Techniques 6. Quantitative Assessment of Renal Perfusion and Oxygenation by Invasive Probes: Basic Concepts Kathleen Cantow, Roger G. Evans, Dirk Grosenick, Thomas Gladytz, Thoralf Niendorf, Bert Flemming, and Erdmann Seeliger 7. Ultrasound and Photoacoustic Imaging of the Kidney: Basic Concepts and Protocols Sandra Meyer, Dieter Fuchs, and Martin Meier 8. Hardware Considerations for Preclinical Magnetic Resonance of the Kidney Paula Ramos Delgado, Ekkehard Küstermann, André Kühne, Jason M. Millward, Thoralf Niendorf, Andreas Pohlmann, and Martin Meier 9. MRI Mapping of Renal T1: Basic Concept Stefanie Hectors, Sabrina Doblas, Philippe Garteiser, Gwenaël Pagé, Bernard E. Van Beers, John C. Waterton, and Octavia Bane 10. MRI Mapping of the Blood Oxygenation Sensitive Parameter T2* in the Kidney: Basic Concept Lu-Ping Li, Bradley Hack, Erdmann Seeliger, and Pottumarthi V. Prasad 11. Renal Diffusion Weighted Imaging (DWI) for Apparent Diffusion Coefficient (ADC), Intra Voxel Incoherent Motion (IVIM), and Diffusion Tensor Imaging (DTI): Basic Concept Neil Peter Jerome, Anna Caroli, and Alexandra Ljimani 12. Dynamic Contrast Enhancement (DCE)-MRI Derived Renal Perfusion and Filtration: Basic Concepts Michael Pedersen, Pietro Irrera, Walter Dastrù, Frank G. Zöllner, Kevin M. Bennett, Scott C. Beeman, G. Larry Bretthorst, Joel R. Garbow, and Dario Livio Longo 13. Non-Invasive Renal Perfusion Measurement Using Arterial Spin Labelling (ASL) MRI: Basic Concept Min-Chi Ku, María A. Fernández-Seara, Frank Kober, and Thoralf Niendorf 14. Renal pH Imaging Using Chemical Exchange Saturation Transfer (CEST)-MRI: Basic Concepts Dario Livio Longo, Pietro Irrera, Lorena Consolino, Phillip Zhe Sun, and Michael T. McMahon 15. Sodium (23Na) MRI of the Kidney: Basic Concept James T. Grist, Esben Søvsø Hansen, Frank G. Zöllner, and Christoffer Laustsen 16. Hyperpolarized Carbon (13C) MRI of the Kidneys: Basic Concepts Cornelius von Morze, Galen D. Reed, Zhen J. Wang, Michael A. Ohliger, and Christoffer Laustsen 17. Functional Imaging Using Fluorine (19F) MR Methods: Basic Concepts Sonia Waiczies, Christian Prinz, Ludger Starke, Jason M. Millward, Paula Ramos Delgado, Jens Rosenberg, Marc Nazaré, Helmar Waiczies, Andreas Pohlmann, and Thoralf Niendorf 18. MR Elastography of the Abdomen: Basic Concepts Suraj D. Serai and Meng Yin Part IV Experimental Protocols 19. Monitoring Renal H
Ultrafast Mri
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Author : Jörg F. Debatin
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Ultrafast Mri written by Jörg F. Debatin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The imaging potential of the MR experiment continues to evolve. In recent years, an increasing number of fast and ultrafast imaging strategies has been described. In this evolu tion the definition of the terms fast and ultrafast has been blurred. Hence they are frequently used interchangeably. The evolution of these methods has been based on two related, yet separate developments: an increasingly thorough understand ing of the complexities inherent to pulse sequence design and the increasing availability of stronger and faster gradient sys tems. The combination of these two factors has laid the foun dation for vast reductions of MRI data acquisition times. Min utes have been replaced by seconds. Beyond shortening MR examination times and thereby increasing patient throughput, a most significant consequence has been the ability to acquire complex MR image sets within the time confines of a single breath-hold. The constraints placed by the presence of respi ratory motion have thus been effectively eliminated. Ultrafast breath-held data acquisition strategies already represent the backbone of many abdominal, thoracic and even pelvic imaging protocols. The enhanced image quality permits full exploitation of the unsurpassed soft tissue contrast inherent to the MR experiment. Beyond improving the quality of ex isting applications, the implementation of ultrafast imaging techniques has permitted the exploration of new imaging in dications, particularly in the area of perfusion and diffusion as well as ultrafast 3D imaging.
Quantitative Evaluation Of An Optimized Time Of Flight Magnetic Resonance Imaging Procedure Using A Phantom Setup To Simulate Aqueous Humor Flow
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Author : Thomas Wecker
language : en
Publisher:
Release Date : 2018
Quantitative Evaluation Of An Optimized Time Of Flight Magnetic Resonance Imaging Procedure Using A Phantom Setup To Simulate Aqueous Humor Flow written by Thomas Wecker and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with categories.
Abstract: Preclinical Magnetic Resonance Imaging at high field strength offers the great advantage of combining anatomical information and very high resolution of down to 25 μm in mice and even higher resolutions in ex vivo settings. The presented data is Time of Flight MR imaging data using a tube phantom and a given flow-rate to determine the lower limit of the flow rate that is detectable with an experimental set-up and a specifically optimized 2D TOF sequence. In this work we present data on a phantom study which shows the ability of Time of Flight MR Imaging to detect very low flow rates down to 25 μl/h at a velocity of 0.1 mm/s non-invasively in a phantom study
Electronic Imaging Techniques
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Author : Eli L. Levitan
language : en
Publisher:
Release Date : 1977
Electronic Imaging Techniques written by Eli L. Levitan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Computers categories.
High Resolution Magnetic Resonance Imaging Of The Bilateral Breasts Using An Accelerated 3d Radial Trajectory
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Author :
language : en
Publisher:
Release Date : 2014
High Resolution Magnetic Resonance Imaging Of The Bilateral Breasts Using An Accelerated 3d Radial Trajectory written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
Breast cancer is the most commonly diagnosed cancer in women in the United States after skin cancer. MRI has been proven to be highly sensitive to breast cancer however it suffers from moderate specificity, resulting in an increased number of false positive. There is the potential to improve the differential diagnosis of breast lesions through better depiction of the morphologic features of interest as well as improving the depiction of contrast kinetics through improved temporal resolution in the DCE scan. This work utilizes the rapid and efficient 3D-radial VIPR pulse sequence to speed the acquisition of MR breast images, allowing for higher spatial and temporal resolution. A Balanced Steady State Free Precession (bSSFP) signal model is developed to combine bSSFP imaging with chemical shift based decomposition, producing robust fat suppression despite large field inhomogeneities in short acquisition times. This model is designed to handle the complex signal behavior expected when a multiple peak spectral fat model is modulated by the frequency response of a bSSFP acquisition. The ability of this model to accurately decompose fat and water is demonstrated in a phantom as well as in vivo imaging at 1.5 T. This signal model is used in conjunction with a bSSFP implementation of VIPR to provide images with T2-like contrast and high 0.63 mm isotropic resolution with robust fat suppression across both breasts in a six minute scan time at 1.5 T. The VIPR pulse sequence is modified to provide bilateral coverage and accommodate the collection of four half echoes for use in chemical shift based fat/water decomposition using an iterative graph cuts algorithm. Results are demonstrated in normal breast volunteers. Finally, VIPR is used to provide high temporal and isotropic spatial resolution during DCE breast imaging. A previously developed version of VIPR was used to obtain promising high spatial and temporal resolution results. Sensitivity to motion and low SNR when using this method provided motivation for the development of bilateral VIPR IDEAL described in this work. While a more thorough analysis of the temporal settings remains to be done, initial results from an ongoing post-contrast study are presented here.
Motion Artifact Reduction In Magnetic Resonance Imaging
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Author : Shreyas Vasanawala
language : en
Publisher:
Release Date : 2000
Motion Artifact Reduction In Magnetic Resonance Imaging written by Shreyas Vasanawala and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with categories.
Rapid And Accurate Single And Multicomponent Relaxometry Using Steady State Acquisitions
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Author :
language : en
Publisher:
Release Date : 2014
Rapid And Accurate Single And Multicomponent Relaxometry Using Steady State Acquisitions written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
Magnetic resonance imaging (MRI) is a medical imaging modality capable of generating images of the soft tissues of the human body in exquisite detail. Unlike most imaging devices, which are based on the attenuation or reflection of visible or x-ray radiation, the image formation process in MR is based on the radiofrequency excitation of water molecules. The level of signal observed and the contrast between various tissues depends on the interaction of these molecules with their local tissue and microstructural environment, and may be described by the fundamental NMR parameters T1 and T2. Additionally, MRI scanners may be programmed with different radiofrequency and magnetic field gradient timings to modify image contrast. Conventional imaging relies on adjusting these timings to weight the signal towards a particular parameter, while quantitative imaging seeks accurate and precise measurements of the fundamental NMR parameters T1 and T2. MRI is an extremely powerful tool for diagnostic imaging as well as basic science studies of the brain, and this work will be focused on neuroimaging applications. In particular, steady state sequences are an attractive choice for performing relaxometry experiments due to their short scan times and moderate to high-resolution volumetric coverage. In spite of these advantages, these methods suffer from a number of effects that reduce their accuracy, in particular strong dependence on the strength and variations of the radiofrequency excitation field (flip angle). A significant portion of this work investigates two methods, Actual Flip-angle Imaging (AFI) and Bloch-Siegert B1 mapping (BS), for correction of these effects. A novel fitting method for AFI is proposed, implemented, and validated. This method improves the accuracy of AFI over a wider range of T1 values and reduces its sensitivity to sequence settings (spoiling). A novel combination of AFI and BS is also proposed, implemented, and validated, enabling correction of imaging sequences employing multiple types of radiofrequency excitation pulses. Most relaxometry techniques measure a single value of T1 and T2 in each voxel. This is valid under the assumption of a single well-mixed pool of water, a condition that does not typically hold for the complex microstructural features of neural tissues. Multicomponent relaxometry is a technique to model multiple pools of water, each with its own T1 and T2 value. The mcDESPOT method is investigated for performing multicomponent relaxometry, using a model of two exchanging pools of water. As this method involves a complicated signal model with as many as 7 free parameters, an analysis of the theoretical and practical precision is performed. mcDESPOT is then demonstrated in vivo on an animal model of dysmyelination that exhibits an extreme paucity of myelin at birth.