Diabetes And The Nervous System
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Diabetes And The Nervous System
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Author : Douglas W. Zochodne
language : en
Publisher: Elsevier
Release Date : 2014-11-05
Diabetes And The Nervous System written by Douglas W. Zochodne and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-05 with Medical categories.
This is a unique compilation, by experts worldwide, addressing how diabetes impacts the nervous system. For example, diabetic polyneuropathy, a disorder more common than MS, Parkinson’s disease, and ALS combined, is a major source of disability to diabetic persons worldwide. This book addresses diabetic polyneuropathy and how diabetes alters other parts of the nervous system. Offers a unique emphasis on the neurological manifestations of diabetes Provides thorough coverage of the clinical, experimental, mechanistic, therapeutic, peripheral, and central aspects of diabetic neuropathy Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available
Prevent Diabetes Problems
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Author :
language : en
Publisher:
Release Date : 2000
Prevent Diabetes Problems written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Diabetes categories.
The Diabetic Neuropathies
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Author : National Institute of Neurological and Communicative Disorders and Stroke. Office of Scientific and Health Reports
language : en
Publisher:
Release Date : 1978
The Diabetic Neuropathies written by National Institute of Neurological and Communicative Disorders and Stroke. Office of Scientific and Health Reports and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with Diabetic neuropathies categories.
Autonomic Nervous System
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Author : Aaron I. Vinik
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-11-11
Autonomic Nervous System written by Aaron I. Vinik and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
Autonomic neuropathy, once considered to be the Cinderella of diabetes complications, has come of age. The autonomic nervous system innervates the entire human body, and is involved in the regulation of every single organ in the body. Thus, perturbations in autonomic function account for everything from abnormalities in pupillary function to gastroparesis, intestinal dysmotility, diabetic diarrhea, genitourinary dysfunction, amongst others. “Know autonomic function and one knows the whole of medicine!” It is now becoming apparent that before the advent of severe pathological damage to the autonomic nervous system there may be an imbalance between the two major arms, namely the sympathetic and parasympathetic nerve fibers that innervate the heart and blood vessels, resulting in abnormalities in heart rate control and vascular dynamics. Cardiac autonomic neuropathy (CAN) has been linked to resting tachycardia, postural hypotension, orthostatic bradycardia and orthostatic tachycardia (POTTS), exercise intolerance, decreased hypoxia-induced respiratory drive, loss of baroreceptor sensitivity, enhanced intraoperative or perioperative cardiovascular lability, increased incidence of asymptomatic ischemia, myocardial infarction, and decreased rate of survival after myocardial infarction and congestive heart failure. Autonomic dysfunction can affect daily activities of individuals with diabetes and may invoke potentially life-threatening outcomes. Intensification of glycemic control in the presence of autonomic dysfunction (more so if combined with peripheral neuropathy) increases the likelihood of sudden death and is a caveat for aggressive glycemic control. Advances in technology, built on decades of research and clinical testing, now make it possible to objectively identify early stages of CAN with the use of careful measurement of time and frequency domain analyses of autonomic function. Fifteen studies using different end points report prevalence rates of 1% to 90%. CAN may be present at diagnosis, and prevalence increases with age, duration of diabetes, obesity, smoking, and poor glycemic control. CAN also cosegregates with distal symmetric polyneuropathy, microangiopathy, and macroangiopathy. It now appears that autonomic imbalance may precede the development of the inflammatory cascade in type 2 diabetes and there is a role for central loss of dopaminergic restraint on sympathetic overactivity. Restoration of dopaminergic tone suppresses the sympathetic dominance and reduces cardiovascular events and mortality by close to 50%. Cinderella’s slipper can now be worn!
Affection Of The Nervous System In Diabetes Mellitus
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Author : V. M. Prikhozhan
language : en
Publisher:
Release Date : 1977
Affection Of The Nervous System In Diabetes Mellitus written by V. M. Prikhozhan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Diabetes categories.
Diabetic Neurology
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Author : Douglas Zochodne
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Diabetic Neurology written by Douglas Zochodne and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.
Diabetic Neurology offers a unique focus on the broad neurological complications of diabetes, bridging the clinical divide between diabetology and neurology with a practitioner-friendly guide for the recognition, investigation and management of diabetic patients with neurological disease.This book provides a comprehensive, practical review of the p
Textbook Of Diabetic Neuropathy
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Author : Friedrich A. Gries
language : en
Publisher: Thieme
Release Date : 2011-01-01
Textbook Of Diabetic Neuropathy written by Friedrich A. Gries and has been published by Thieme this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-01 with Medical categories.
Awareness of neuropathy as a chronic complication of diabetes is constantly increasing. Diabetes centers adopt methods to diagnose neuropathy without neurological training. This trend calls for instructions on how to use and interpret diagnostic methods. This book includes recent research and covers clinical, technical, and public health aspects of neuropathy, bringing together the top experts in the field.
Diabetic Neuropathy
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Author : Aristidis Veves
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-01
Diabetic Neuropathy written by Aristidis Veves and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-01 with Medical categories.
In this updated edition, leading medical specialists critically review for the general practitioner the latest techniques for the clinical management of diabetic neuropathy. The contributors focus on the practical aspects of diabetic neuropathy and describe in detail the treatments that are currently available or expected to become available in the near future. They also include concise discussions of the pathogenesis of diabetic neuropathy.
Textbook Of Diabetic Neuropathy
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Author : Henning Andersen
language : en
Publisher: Thieme
Release Date : 2002-12-18
Textbook Of Diabetic Neuropathy written by Henning Andersen and has been published by Thieme this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-12-18 with Medical categories.
Awareness of neuropathy as a chronic complication of diabetes is constantly increasing. Diabetes centers adopt methods to diagnose neuropathy without neurological training. This trend calls for instructions on how to use and interpret diagnostic methods. This book includes recent research and covers clinical, technical, and public health aspects of neuropathy, bringing together the top experts in the field.
Autonomic Nervous System
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Author : Philip E. Cryer
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-11-11
Autonomic Nervous System written by Philip E. Cryer and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
The concept of hypoglycemia-associated autonomic failure (HAAF) in diabetes posits that recent antecedent hypoglycemia, as well as sleep or prior exercise, causes both defective glucose counterregulation (by attenuating the adrenomedullary epinephrine response, in the setting of absent insulin and glucagon responses) and hypoglycemia unawareness (by attenuating the sympathoadrenal, largely the sympathetic neural, response) and thus a vicious cycle of recurrent hypoglycemia. Albeit with different time courses, the pathophysiology of defense against hypoglycemia – no decrease in therapeutic insulin, no increase in glucagon and an attenuated increase in sympathoadrenal activity – is the same in type 1 diabetes and advanced type 2 diabetes. Hypoglycemia unawareness is reversible by 2–3 weeks of scrupulous avoidance of hypoglycemia in most affected patients. The pathophysiology of HAAF in diabetes explains why the incidence of hypoglycemia increases as patients approach the absolute endogenous insulin deficient end of the disease, provides a comprehensive set of risk factors including those indicative of HAAF, and leads logically to the practice of hypoglycemia risk factor reduction. Because of the risk of hypoglycemic mortality, presumably from cardiac arrhythmias, glycemic goals in diabetes should be individualized, based in part on the risk of hypoglycemia. By practicing hypoglycemia risk reduction – addressing the issue, applying the principles of aggressive glycemic therapy and considering both the conventional risk factors and those indicative of HAAF – it is possible to both improve glycemic control and reduce the risk of hypoglycemia in many patients with diabetes.