Diabetic Bone Disease


Diabetic Bone Disease
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Diabetic Bone Disease


Diabetic Bone Disease
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Author : Beata Lecka-Czernik
language : en
Publisher: Springer
Release Date : 2015-10-12

Diabetic Bone Disease written by Beata Lecka-Czernik and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-12 with Medical categories.


Providing the most up-to-date research and current clinical knowledge of diabetic bone disease and the challenges still facing the research and clinical care communities, this book unites insights from endocrinology and orthopedics to create a truly unique text. The first part covers clinical and pre-clinical applications and research. The first two chapters present the clinical and epidemiological data about diabetic bone disease, evaluated and reviewed for type 1 and type 2, respectively. This is followed by discussions of how the propensity to fracture in diabetic bone disease can impact fracture risk assessments and how it can be adjusted for using current clinically relevant fracture risk models. A comprehensive overview of orthopedic complications observed in diabetes is next, as well as a focus on the consequences of diabetes on periodontal disease. Other topics include the utility of skeletal biomarkers in assessing diabetic bone disease, how drugs used to treat diabetes may also have skeletal consequences, and the possibility that diabetes may fundamentally impact early progenitor cells of various bone lineages and thus globally impact bone. The second part covers biomechanics and bone quality in diabetes: how diabetes ultimately may impact the architecture, integrity, and quality of bone. Utilizing the expertise of top researcher and clinicians in diabetic bone disease in one comprehensive text, this volume will be a useful and thought-provoking resource for endocrinologists and orthopedic surgeons alike.



Diabetic Bone Disease


Diabetic Bone Disease
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Author : Beata Lecka-Czernik
language : en
Publisher:
Release Date : 2016

Diabetic Bone Disease written by Beata Lecka-Czernik and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Bones categories.


Providing the most up-to-date research and current clinical knowledge of diabetic bone disease and the challenges still facing the research and clinical care communities, this book unites insights from endocrinology to orthopedics to create a truly unique text. The first part covers clinical and pre-clinical applications and research. The first two chapters present the clinical and epidemiological data about diabetic bone disease, evaluated and reviewed for type 1 and type 2, respectively. This is followed by discussions of how the propensity to fracture in diabetic bone disease can impact fracture risk assessments and how it can be adjusted for using current clinically relevant fracture risk models. A comprehensive overview of orthopedic complications observed in diabetes is next, as well as a focus on the consequences of diabetes on periodontal disease. Other topics include the utility of skeletal biomarkers in assessing diabetic bone disease, how drugs used to treat diabetes may also have skeletal consequences, and the possibility that diabetes may fundamentally impact early progenitor cells of various bone lineages and thus globally impact bone. The second part covers biomechanics and bone quality in diabetes: how diabetes ultimately may impact the architecture, integrity, and quality of bone. Utilizing the expertise of top researchers and clinicians in diabetic bone disease in one comprehensive text, this volume will be a useful and thought-provoking resource for endocrinologists and orthopedic surgeons alike.



Diabetic Bone Disease


Diabetic Bone Disease
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Author : Friedrich Kuhlencordt
language : en
Publisher:
Release Date : 1988*

Diabetic Bone Disease written by Friedrich Kuhlencordt and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988* with Bones categories.




Bones And Joints In Diabetes Mellitus


Bones And Joints In Diabetes Mellitus
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Author : S. Forgács
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Bones And Joints In Diabetes Mellitus written by S. Forgács and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Complex disorders of the carbohydrate metabolism and associated complications cause many abnormalities detectable by radiography in the bones and joints. Mild clinical symptoms associated with very severe radiological changes were first rec ognized in relation to the gastroenterologic complications of diabetes. This phenomenon is more frequent in the skeletal system. For example, mild and painless swelling of the foot joints may often mask extremely severe bone destruction. Several other bone changes associated with diabetes are only detectable by radiography. Thus, the radiologist plays an important role in confirming these diabetic complications, furthermore he is involved in the therapeutic management of the patient. Although many details on this subject have been published, however no summarizing monograph has yet appeared. Manuals discussing diabetes include only short reviews on complications of the osseous system. The fact that the incidence of diabetes is very high, at present 1 %-2 % of the population is affected and their number is gradually increasing - dis plays the timeliness of this subject. Fifty years of experience with insulin therapy indicates that several important problems still remain to be solved. Insulin and modern oral antidia betic drugs proved extremely efficient in the management of hyperglycemia and ketosis, but the incidence of other complications has not decreased. Moreover, as the number of diabetics and their life expectancy increase, late complications become likewise more fre quent. Diabetic osteoarthropathy is one of these complications.



Diabetes Mellitus


Diabetes Mellitus
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Author : Meng Hee Tan
language : en
Publisher: Academic Press
Release Date : 2020-07-28

Diabetes Mellitus written by Meng Hee Tan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-28 with Medical categories.


Diabetes Mellitus: Impact on Bone, Dental and Musculoskeletal Health focuses on the under recognized and managed conditions associated with diabetes, including impacts on bone health, dental health, hand, and foot disorders, wounds, infections, and musculoskeletal disorders. A full understanding of the relationship of diabetes to skeletal disorders remains elusive and many physicians who deal with such issues are unclear about causes and management. While the macro- and microvascular complications associated with diabetes mellitus are well known, complications associated with bone, dental and musculoskeletal health are not. Endocrinologists, primary care physicians, geriatricians, podiatrists, dentists, and researchers interested in diabetes mellitus associated bone, dental and musculoskeletal disorders will find this to be a comprehensive tome on the topic. Covers clinically important complications of diabetes that are less understood Presents up-to-date, thoroughly referenced information for both clinicians, researchers and other healthcare providers Highlights current research and treatment for skeletal deficits and complications due to diabetes types 1 and 2 Serves as a one-stop resource for the bone, dental and muscular disorders associated with diabetes mellitus



Diabetes Complications Comorbidities And Related Disorders


Diabetes Complications Comorbidities And Related Disorders
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Author : Enzo Bonora
language : en
Publisher: Springer
Release Date : 2020-04-02

Diabetes Complications Comorbidities And Related Disorders written by Enzo Bonora and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-02 with Medical categories.


This book provides the reader with comprehensive information on the interactions between diabetes and a wide range of comorbid conditions and on disease management in such patients. It has the aim of empowering health care providers in their daily battle against the disease and its consequences. Diabetes has been identified by WHO and the United Nations as a medical emergency because of the increase in its global prevalence, which may reach one billion in three to four decades if the trend remains unchanged. Despite improved care that is helping to prolong life, diabetes impacts substantially on the quality of life of those affected and kills or disables several million people each year. The disease is systemic because all organs, tissues, and cells suffer in the presence of hyperglycemia and are damaged by the diabetic milieu. Unfortunately, most patients with diabetes will consequently experience chronic diabetic complications. This book will be of value for all physicians and nurses who care for patients with diabetes and face the challenge of treating hyperglycemia and related acute and chronic complications.



Musculoskeletal Disease Associated With Diabetes Mellitus


Musculoskeletal Disease Associated With Diabetes Mellitus
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Author : Masaaki Inaba
language : en
Publisher: Springer
Release Date : 2016-01-06

Musculoskeletal Disease Associated With Diabetes Mellitus written by Masaaki Inaba and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-06 with Medical categories.


The aim of this book is to review the latest findings on musculoskeletal disease associated with diabetes. It has been increasingly recognized that maintaining skeletal health is an important factor in achieving longevity in healthy subjects. Diabetes has been established as a disease independently associated with sarcopenia and increased risk of bone fracture resulting from osteoporosis; therefore, it is reasonable to maintain that musculoskeletal health is important in preserving good health. As either bone or muscle is intimately involved in the regulation of metabolic status, keeping the musculoskeletal system healthy is important for improving abnormal glucose metabolism toward normal levels and is vital, as well, for maintaining normal activities of daily living. Muscle is a target of insulin for enhancing the entry of glucose; thus it is conceivable that sarcopenia and muscle containing fat streaks causes insulin resistance in diabetic patients. Furthermore, bone is an organ that regulates Ca and Pi levels in serum by releasing or resorbing Ca and Pi to and from bone tissue. It is now known that bone is a definitive endocrine organ for regulating glucose metabolism and Pi metabolism by secreting osteocalcin and FGF-23 from osteocytes/osteoblasts. Readers will learn of the recent findings in this area, and this book will benefit physicians who deal with diabetes, particularly orthopedists and bone specialists, as well as all physical therapists.



Biomarkers In Bone Disease


Biomarkers In Bone Disease
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Author : Victor R. Preedy
language : en
Publisher: Springer
Release Date : 2017-07-14

Biomarkers In Bone Disease written by Victor R. Preedy and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-14 with Medical categories.


In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease. The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics, and so on. The chapters are written by national or international experts and specialists.



Chronic Complications Of Diabetes Mellitus


Chronic Complications Of Diabetes Mellitus
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Author : Didac Mauricio
language : en
Publisher: Elsevier
Release Date : 2024-03-29

Chronic Complications Of Diabetes Mellitus written by Didac Mauricio and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-29 with Medical categories.


Chronic Complications of Diabetes Mellitus: Current Outlook and Novel Pathophysiological Insights provides a holistic view of the disease, discussing not only its classical complications but also the under recognized and managed conditions associated with diabetes. Chapters also discuss advances in our understanding of the genomic architecture of diabetes complications and how precision medicine can be used to personalize their management. Endocrinologists, diabetologists, primary care physicians and researchers interested in complications of diabetes mellitus and cutting-edge information will find this to be a comprehensive tome on the topic. Diabetes complications include pathological changes usually related to the vascular system and classical target organs. However, there are also nonclassical complications independent or partially independent from vascular damage that are often overlooked. Describes pathophysiology, clinical aspects and treatment of complications of diabetes, including nonclassical complications such as diabetic bone disease and diabetic cardiomyopathy Addresses and discusses challenges in the management of diabetes complications, including prevention and therapeutic strategies Presents up-to-date, thoroughly referenced information for clinicians, researchers and other healthcare providers



Primer On The Metabolic Bone Diseases And Disorders Of Mineral Metabolism


Primer On The Metabolic Bone Diseases And Disorders Of Mineral Metabolism
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Author : Juliet E. Compston
language : en
Publisher: John Wiley & Sons
Release Date : 2009-12-22

Primer On The Metabolic Bone Diseases And Disorders Of Mineral Metabolism written by Juliet E. Compston and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-22 with Science categories.


EDITOR-IN-CHIEF: Clifford J. Rosen, M.D., Maine Medical Center Research Institute, Scarborough, Maine SENIOR ASSOCIATE EDITORS: Juliet E. Compston, M.D., FRCP, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom Jane B. Lian, Ph.D., University of Massachusetts Medical School, Worcester, Massachusetts This comprehensive yet concise handbook is an indispensable reference for the many clinicians who see patients with disorders of bone formation, metabolic bone diseases, or disorders of stone formation. It is also a crucial tool for researchers, students, and all other professionals working in the bone field. In a format designed for quick reference, it provides complete information on the symptoms, pathophysiology, diagnosis, and treatment of all common and rare bone and mineral disorders. New in this edition: detailed coverage of osteonecrosis of the jaw, more in-depth coverage of cancer and bone including new approaches to pathogenesis, diagnosis, and treatment; new approaches to anabolic therapy of osteoporosis; the latest research on Vitamin D; expanded coverage of international topics; more on the genetics of bone mass; and newer imaging techniques for the skeleton. In addition, this edition features a free, online-only appendix of medicines used to treat bone disorders and their availability around the world.