Disordered
DOWNLOAD
Download Disordered PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Disordered book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Structure And Function Of Intrinsically Disordered Proteins
DOWNLOAD
Author : Peter Tompa
language : en
Publisher: CRC Press
Release Date : 2009-11-18
Structure And Function Of Intrinsically Disordered Proteins written by Peter Tompa and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-18 with Science categories.
The existence and functioning of intrinsically disordered proteins (IDPs) challenge the classical structure-function paradigm that equates function with a well-defined 3D structure. Uncovering the disordered complement of proteomes and understanding their functioning can extend the structure-function paradigm to herald new breakthroughs in drug dev
Intrinsically Disordered Proteins
DOWNLOAD
Author : Nicola Salvi
language : en
Publisher: Academic Press
Release Date : 2019-06-14
Intrinsically Disordered Proteins written by Nicola Salvi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-14 with Science categories.
Intrinsically Disordered Proteins: Dynamics, Binding, and Function thoroughly examines and ties together the fundamental biochemical functions of intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs), including signaling, binding, and regulation, with the methodology for study and the associated pathways for drug design and therapeutic intervention. The role of new mechanistic, computational, and experimental approaches in IDP study are explored in depth, with methods for the characterization of IDP dynamics; models, simulations, and mechanisms of IDP and IDR binding; and biological and medical implications of IDP dynamics prominently featured. Written and edited by leading scientists in the field, this book explores groundbreaking areas such as ensemble descriptions of IDPs and IDRs, single-molecule studies of IDPs and IDRs, IDPs and IDRs in membraneless organelles, and molecular mechanisms of fibrillation of IDPs. Intrinsically Disordered Proteins provides students and researchers in biochemistry, molecular biology, and applied microbiology with a comprehensive and updated discussion of the complex dynamics of IDPs and IDRs. Provides in-depth discussion of fundamental IDP and IDR dynamics, function, and binding, with mechanistic insight to support new drug development Describes the role of new computational and experimental approaches in characterizing the binding of IDPs to their functional targets Features chapter contributions from international experts in IDP and IDR biochemical function and methods of study
Intrinsically Disordered Proteins
DOWNLOAD
Author :
language : en
Publisher: Academic Press
Release Date : 2018-11-21
Intrinsically Disordered Proteins written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-21 with Science categories.
Intrinsically Disordered Proteins, Volume 611, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics of interest, including the Characterization of Structure-Function relationships in the intrinsically disordered protein complexin, Distances, distance distributions, and ensembles of IDPs from single-molecule FRET, Biophysical characterization of disordered protein liquid phases, The Use of Mass Spectrometry to Examine IDPs – Unique Insights and Caveats, Fluorescence Depolarization Kinetics to Study Conformational Preference, Structural Plasticity and Membrane Binding of Intrinsically Disordered Proteins, Characterizing the Function of Intrinsically Disordered Proteins in the Circadian Clock, and more. Breadth of experimental approaches and systems that will be covered The expertise of the contributors writing the articles
Violence Crime And Mentally Disordered Offenders
DOWNLOAD
Author : Sheilagh Hodgins
language : en
Publisher: John Wiley & Sons
Release Date : 2000-06-08
Violence Crime And Mentally Disordered Offenders written by Sheilagh Hodgins and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-06-08 with Psychology categories.
The mentally disordered criminal is a public nightmare, and themanagement of these offenders can be driven as much by politicaland economic concerns as by scientific evidence and professionaljudgement within the fields of mental health and correctionservices. This book aims to provide a critical and focused reviewof knowledge and best practice in this field for mental health andcorrection professionals and for those concerned with policy andmanagement of services for these offenders. Mentally disordered offenders include offenders who suffer fromschizophrenia, major affective disorders, personality disorders(including psychopathy), brain damage, and mental retardation. Thetopic is of increasing importance because of the growth ofcommunity psychiatry, and the growing community programmes foroffenders, and also because of the growing pressures on thoseinstitutions which deal with offenders and care for the mentallydisordered or disabled. Professionals in these fields will welcomethis book which: * Provides a review of approaches to treatment, accessible to awide mental health and forensic readership * Relates treatment approaches to specific mental problems, andreviews evidence of effectiveness * features a truly international group of authors bringing togethera wide variety of approaches, scientific research, and practicalexperience of important programmes for treatment and prevention "Few recent texts provide both the depth and breadth necessary tounderstand the vexing behaviour of mentally disordered offenders.Drs Hodgins and Muller-Isberner, a remarkable pairing of researchand clinical expertise, have put together a highly readable andsuperb resource for anyone interested in this interface of seriousmental illness and criminal behavior. The authors of theconstituent chapters are leading authorities in their respectiveareas and have provided thoughtful commentary on the most recentinternational literature. This is a first-rate treatment of arapidly growing and fascinating field." Marvin Swartz, DukeUniversity, USA
Dancing Protein Clouds Intrinsically Disordered Proteins In The Norm And Pathology
DOWNLOAD
Author : Vladimir Uversky
language : en
Publisher: Academic Press
Release Date : 2019-09-15
Dancing Protein Clouds Intrinsically Disordered Proteins In The Norm And Pathology written by Vladimir Uversky and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-15 with categories.
"Dancing protein clouds: Intrinsically disordered proteins in the norm and pathology" represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this update include structural and functional characterization of several important intrinsically disordered proteins, such as 14-3-3 proteins and their partners, as well as proteins from muscle sarcomere; representation of intrinsic disorder-related concept of protein structure-function continuum; discussion of the role of intrinsic disorder in phenotypic switching; consideration of the role of intrinsically disordered proteins in the pathogenesis of neurodegenerative diseases and cancer; discussion of the roles of intrinsic disorder in functional amyloids; demonstration of the usefulness of the analysis of translational diffusion of unfolded and intrinsically disordered proteins; consideration of various computational tools for evaluation of functions of intrinsically disordered regions; and discussion of the role of shear stress in the amyloid formation of intrinsically disordered regions in the brain. Provides some recent studies on the intrinsically disordered proteins and their functions, as well as on the involvement of intrinsically disordered proteins in pthogenesis of various diseases Contains numerous illustrative materials (color figures, diagrams, and tables) to help the readers to delve in the information provided Includes contributions from recognized experts in the field
Disordered Semiconductors Second Edition
DOWNLOAD
Author : Anatoly Popov
language : en
Publisher: CRC Press
Release Date : 2018-08-01
Disordered Semiconductors Second Edition written by Anatoly Popov and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-01 with Science categories.
Devices based on disordered semiconductors have wide applications. It is difficult to imagine modern life without printers and copiers, LCD monitors and TVs, optical disks, economical solar cells, and many other devices based on disordered semiconductors. However, nowadays books that discuss disordered (amorphous, nanocrystalline, microcrystalline)
The Wiley Blackwell Handbook Of Disordered Gambling
DOWNLOAD
Author : David C. S. Richard
language : en
Publisher: John Wiley & Sons
Release Date : 2013-12-04
The Wiley Blackwell Handbook Of Disordered Gambling written by David C. S. Richard and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-04 with Psychology categories.
The Wiley-Blackwell Handbook of Disordered Gambling is a complete guide to the current empirical literature relating to the conceptualization, assessment, and treatment of disordered gambling. The international contributors are all experienced, practicing clinicians who discuss gambling within a global context. Best-practice guidelines for the clinical management of problem and disordered gambling Contains empirically derived findings that translate research into practical clinical applications that clinicians and counselors can use in understanding and treating problem gamblers Brings together a distinguished international group of scholars whose contributions discuss gambling as it occurs around the globe Clearly organized into sections that cover conceptualization, research, assessment, treatment, and special topics
The Disordered Body
DOWNLOAD
Author : Suzanne E. Hatty
language : en
Publisher: State University of New York Press
Release Date : 1999-11-04
The Disordered Body written by Suzanne E. Hatty and has been published by State University of New York Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-11-04 with Social Science categories.
The Disordered Body presents a fascinating look at how three epidemics of the medieval and Early Renaissance period in Western Europe shaped and altered conceptions of the human body in ways that continue today. Authors Suzanne E. Hatty and James Hatty show the ways in which concepts of the disordered body relate to constructions of disease. In so doing, they establish a historical link between the discourses of the disordered body and the constructs of gender. The ideas of embodiment, contagion and social space are placed in historical context, and the authors argue that our current anxieties about bodies and places have important historical precedents. They show how the cultural practices of embodied social interaction have been shaped by disease, especially epidemics.
The Sociology Of The Mentally Disordered Offender
DOWNLOAD
Author : Tom Mason
language : en
Publisher: Routledge
Release Date : 2014-06-11
The Sociology Of The Mentally Disordered Offender written by Tom Mason and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-11 with Social Science categories.
In recent years mentally disordered offenders have attracted considerable attention in the media and there has been heated public debate as to the best treatment and prevention of re-offending. Simultaneously there has been a significant increase in the amount of research, specialist courses and training devoted to this particular, high profile area of mental health care. This is as a result of considerable public pressure to develop effective theory and practice for diagnosing and treating this patient group.A Sociology of the Mentally Disordered Offender provides a concise, and most importantly, accessible guide to the main theoretical issues from a sociological perspective as a counterbalance to the predominant medical model. Having established a theoretical framework through the exploration of topics such as the relationship between crime and mental disorder the authors look at the processes by which offenders are referred either to criminal justice or the mental health service system, their subsequent treatment and management, and the problem of re-offending. A final chapter looks at ways in which care and management of these patients may be effectively developed in the future.
Diversion From Custody For Mentally Disordered Offenders
DOWNLOAD
Author : Catherine Staite
language : en
Publisher: Routledge
Release Date : 2017-09-29
Diversion From Custody For Mentally Disordered Offenders written by Catherine Staite and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-29 with Social Science categories.
The authors aim to provide practical guidance to enable practitioners in the various criminal justice, health and social care agencies to divert mentally disordered offenders from prosecution and custody and to help prevent re-offending.