Dna Nanotechnology For Bioanalysis From Hybrid Dna Nanostructures To Functional Devices
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Dna Nanotechnology For Bioanalysis From Hybrid Dna Nanostructures To Functional Devices
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Author : Arrabito Giuseppe Domenico
language : en
Publisher: World Scientific
Release Date : 2017-09-25
Dna Nanotechnology For Bioanalysis From Hybrid Dna Nanostructures To Functional Devices written by Arrabito Giuseppe Domenico and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-25 with Technology & Engineering categories.
This book is intended for non-specialists and students, presenting a unique introduction to the field of DNA nanotechnology. The primary focus is on the extraordinary advantages of specificity and sensitivity obtained by integrating DNA nanostructures in bioanalytical devices. DNA Nanotechnology for Bioanalysis provides a concise and rigorous description for the fabrication of various types of functional nanostructures by optimized software-aided high-yield synthesis. Following this is the explanation of methods to decorate these nanostructures with molecules such as proteins, metal nanoparticles or bioorganic moieties covalently bonded onto DNA via self-assemblage processes. Also provided is a concise review on non-canonical DNA structures (such as G-quadruplexes) and their targeting by small molecules for applications in pharmacology. Finally, it describes the exciting applications of DNA nanostructures in life sciences and nanomedicine, including ultraspecific molecular delivery, control of cell behavior, analysis of cell lysate and DNA-based nano-tools for super-resolution sub-cellular imaging. Contents: Nanotechnology and the Unique Role of DNA (Elisa-C Schöneweiβ, Andreas Jaekel and Barbara Saccà)DNA as Building Material at the Nanoscale: From Concepts to Software-aided Design (Wolfgang Pfeifer, Georg Homa, Giuseppe Arrabito and Barbara Saccà)DNA Sensors for the Detection of Biomolecules and Biochemical Conditions (Birgitta R Knudsen, Anni H Andersen, Magnus Stougaard, Giuseppe Arrabito, Raffaella Suriano and Yi-Ping Ho)DNA Nanostructures in Cell Biology and Medicine (Liqian Wang and Giuseppe Arrabito)Targeting G-quadruplex DNA as Potential Anti-cancer Therapy (Riccardo Bonsignore, Elisa Trippodo and Giampaolo Barone)DNA-aided Super-resolution Bioimaging (JiaJun Li, Giuseppe Arrabito and ZhaoShuai Gao) Readership: Non-specialists, undergraduate students and researchers who are interested in learning the basics of DNA nanotechnology. Keywords: DNA Nanotechnology;Nanostructures;Non-Canonical DNA Structures;G Quadruplexes;Nano-Tools;DNA Origami;DNA Aptamers;Biosensors;Drug DeliveryReview: Key Features: Constitutes a clear introduction to the field of DNA NanotechnologyWritten in an easy and catchy styleContains information of the most recent findings in the world of DNA Nanotechnology (up to 2016), optimal for researchers who want to keep updated with the latest breakthroughs in the field
Dna Nanotechnology For Cell Research
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Author : Zhou Nie
language : en
Publisher: John Wiley & Sons
Release Date : 2024-02-20
Dna Nanotechnology For Cell Research written by Zhou Nie and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-20 with Science categories.
DNA Nanotechnology for Cell Research Comprehensive coverage of DNA nanotechnology with a focus on its biomedical applications in disease diagnosis, gene therapy, and drug delivery Bringing together multidisciplinary aspects of chemical, material, and biological engineering, DNA Nanotechnology for Cell Research: From Bioanalysis to Biomedicine presents an overview of DNA nanotechnology with emphasis on a variety of different applications in cell research and engineering, covering a unique collection of DNA nanotechnology for fundamental research and engineering of living cells, mostly in cellulo and in vivo, for the first time. Broad coverage of this book ranges from pioneering concepts of DNA nanotechnology to cutting-edge reports regarding the use of DNA nanotechnology for fundamental cell science and related biomedical engineering applications in sensing, bioimaging, cell manipulation, gene therapy, and drug delivery. The text is divided into four parts. Part I surveys the progress of functional DNA nanotechnology tools for cellular recognition. Part II illustrates the use of DNA-based biochemical sensors to monitor and image intracellular molecules and processes. Part III examines the use of DNA to regulate biological functions of individual cells. Part IV elucidates the use of DNA nanotechnology for cell-targeted medical applications. Sample topics covered in DNA Nanotechnology for Cell Research include: Selections and applications of functional nucleic acid toolkits, including DNA/RNA aptamers, DNAzymes, and riboswitches, for cellular recognition, metabolite detection, and liquid biopsy. Developing intelligent DNA nanodevices implemented in living cells for amplified cell imaging, smart intracellular sensing, and in cellulo programmable biocomputing. Harnessing dynamic DNA nanotechnology for non-genetic cell membrane engineering, receptor signaling reprogramming, and cellular behavior regulation. Construction of biocompatible nucleic acid nanostructures as precisely controlled vehicles for drug delivery, immunotherapy, and tissue engineering. Providing an up-to-date tutorial style overview along with a highly valuable in-depth perspective, DNA Nanotechnology for Cell Research is an essential resource for the entire DNA-based nanotechnology community, including analytical chemists, biochemists, materials scientists, and bioengineers.
Templated Dna Nanotechnology
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Author : Thimmaiah Govindaraju
language : en
Publisher: CRC Press
Release Date : 2019-01-30
Templated Dna Nanotechnology written by Thimmaiah Govindaraju and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-30 with Science categories.
Nucleic acids have structurally evolved over billions of years to effectively store and transfer genetic information. In the 1980s, Nadrian Seeman’s idea of constructing a 3D lattice from DNA led to utilizing DNA as nanomolecular building blocks to create emergent molecular systems and nanomaterial objects. This bottom-up approach to construct nanoscale architectures with DNA marked the beginning of a new field, DNA nanotechnology, contributing significantly to the broad area of nanoscience and nanotechnology. The molecular architectonics of small "designer" molecules and short DNA sequences through complementary binding interaction engenders well-defined functional nanoarchitectures with realistic applications in areas ranging from biology to materials science and is termed "DNA nanoarchitectonics." This book discusses novel approaches adapted by leading researchers from all over the world to create functional nucleic acid molecular systems and nanoarchitectures. Individual chapters contributed by active practitioners provide fundamental and advanced knowledge emanated from their own and others’ work. Each chapter includes numerous illustrations, historical perspectives, case studies and practical examples, critical discussions, and future prospects. This book can serve as a practical handbook or as a textbook for advanced undergraduate- and graduate-level students of nanotechnology and DNA nanotechnology, supramolecular chemistry, and nanoarchitectonics and researchers working on macromolecular science, nanotechnology, chemistry, biology, and medicine, especially those with an interest in sensors, biosensors, nanoswitches and nanodevices, diagnostics, drug delivery, and therapeutics.
Dna In Supramolecular Chemistry And Nanotechnology
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Author : Eugen Stulz
language : en
Publisher: John Wiley & Sons
Release Date : 2015-09-28
Dna In Supramolecular Chemistry And Nanotechnology written by Eugen Stulz and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-28 with Technology & Engineering categories.
This book covers the emerging topic of DNA nanotechnology and DNA supramolecular chemistry in its broader sense. By taking DNA out of its biological role, this biomolecule has become a very versatile building block in materials chemistry, supramolecular chemistry and bio-nanotechnology. Many novel structures have been realized in the past decade, which are now being used to create molecular machines, drug delivery systems, diagnosis platforms or potential electronic devices. The book combines many aspects of DNA nanotechnology, including formation of functional structures based on covalent and non-covalent systems, DNA origami, DNA based switches, DNA machines, and alternative structures and templates. This broad coverage is very appealing since it combines both the synthesis of modified DNA as well as designer concepts to successfully plan and make DNA nanostructures. Contributing authors have provided first a general introduction for the non-specialist reader, followed by a more in-depth analysis and presentation of their topic. In this way the book is attractive and useful for both the non-specialist who would like to have an overview of the topic, as well as the specialist reader who requires more information and inspiration to foster their own research.
Dna Nanotechnology
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Author : Chunhai Fan
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-12
Dna Nanotechnology written by Chunhai Fan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-12 with Technology & Engineering categories.
DNA nanotechnology: From structure to function presents an overview of various facets of DNA nanotechnology, with a particular focus on their promising applications. This book is composed of three parts. Part I, Elements of DNA Nanotechnology, provides extensive basic information on DNA nanotechnology. Part II, Static and Dynamic DNA Nanotechnology, describes the design and fabrication of static and dynamic DNA nanostructures. Recent advances in DNA origami, DNA walkers and DNA nanodevices are all covered in this part. Part III, Applications of DNA Nanotechnology, introduces a variety of applications of DNA nanotechnology, including biosensing, computation, drug delivery, etc. Together these provide a comprehensive overview of this emerging area and its broad impact on biological and medical sciences. This book is intended for post-graduates, post-doctoral researchers and research scientists who are interested in expanding their knowledge of DNA nanotechnology. It provides readers an impression of the latest developments in this exciting filed.
Engineered Nanopores For Bioanalytical Applications
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Author : Joshua B. Edel
language : en
Publisher: William Andrew
Release Date : 2013-03-19
Engineered Nanopores For Bioanalytical Applications written by Joshua B. Edel and has been published by William Andrew this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-19 with Science categories.
Engineered Nanopores for Bioanalytical Applications is the first book to focus primarily on practical analytical applications of nanopore development. These nanoscale analytical techniques have exciting potential because they can be used in applications such as DNA sequencing, DNA fragment sizing, DNA/protein binding, and protein/protein binding. This book provides a solid professional reference on nanopores for readers in academia, industry and engineering and biomedical fields. In addition, the book describes the instrumentation, fabrication, and experimental methods necessary to carry out nanopore-based experiments for developing new devices. Includes application case studies for detection, identification and analysis of biomolecules and related functional nanomaterials Introduces the techniques of manufacturing solid state materials with functional nanopores Explains the use of nanopores in DNA sequencing and the wider range of applications from environmental monitoring to forensics
Visions Of Dna Nanotechnology At 40 For The Next 40
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Author : Nataša Jonoska
language : en
Publisher: Springer Nature
Release Date : 2023-07-04
Visions Of Dna Nanotechnology At 40 For The Next 40 written by Nataša Jonoska and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-04 with Computers categories.
This open access book provides a unique and state-of-the-art view on DNA nanotechnology with an eye toward future developments. Intended as a tribute to Nadrian C. Seeman, who founded the field of DNA nanotechnology, the content is an exciting mixture of technical and non-technical material, reviews, tutorials, perspectives, new findings, and open questions. The book aims to inspire current researchers to sit back and think about the big picture, while also enticing new researchers to enter the field. Most of all, the book captures voices from a unique moment in time: 40 years after the publication of the first paper that envisioned DNA nanotechnology. From this vantage point, what are the untold stories, the unspoken concerns, the underlying fundamental issues, the overlooked opportunities, and the unifying grand challenges? What will help us see more clearly, see more creatively, or see farther? What is transpiring right now that could pave the way for the future? To address these questions, leading researchers have contributed 22 chapters, grouped into five sections: perspectives, chemistry and physics, structures, biochemical circuits, and spatial systems. This book will be an important reference point in the field of DNA nanotechnology, both for established researchers looking to take stock of the field and its future, and for newcomers such as graduate students and researchers in other fields who are beginning to appreciate the power and applicability of its methods.
Dna Nanotechnology
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Author : Giampaolo Zuccheri
language : en
Publisher: Humana
Release Date : 2016-08-23
Dna Nanotechnology written by Giampaolo Zuccheri and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-23 with Science categories.
Currently, nanotechnology is exposing the properties of DNA in unprecedented detail leading to new insights on the biological behavior and function of DNA. With the structural perfection of a self-assembling DNA nano-object, such as a DNA origami, it is clear how complex DNA is as a molecule, leading researchers to wonder how many different constructs could be designed and realized. DNA Nanotechnology: Methods and Protocols shows the procedures to follow in order to repeat methods that lead to such constructs or to the mastering of the characterization techniques used to study them. The chapters of this book are roughly divided into two parts: some cover the methods for preparing the nanostructures, from the rationale of the operations to the techniques for their handling, while other chapters deal more directly with advanced instrumental techniques that can manipulate and characterize molecules and nanostructures. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, DNA Nanotechnology: Methods and Protocols serves as an ideal guide to scientists of all backgrounds and aims to ignite interest and spur activity in this young and rapidly growing research field. Includes cutting-edge methods and protocols Provides step-by-step detail essential for reproducible results Contains key notes and implementation advice from the experts
Noble Metal Nanoparticles
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Author : Ignác Capek
language : en
Publisher: Springer
Release Date : 2017-07-20
Noble Metal Nanoparticles written by Ignác Capek and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-20 with Science categories.
This book introduces the reader the chemistry of reaction approaches by which noble metal nanoparticles are synthesized, including synthetic approaches using the Brust–Schiffrin method , a high-temperature solution-phase synthesis, polymer and biological entities, weak and strong reducing and capping agents, the low and high temperatures, various additives and various novel approaches such as plasma, ionic liquids, UV light and gamma rays and others. This book starts with a brief overview of foundation work concerned with the chapter topics such as nanomaterials, nanoscience, surface-capping molecules, traditional and nontraditional reduction agents, In addition, chemical and physical properties of noble metal nanoparticles with different structures and elements such as monolayered clusters, nanorods, and bimetallic nanoparticles are described comprehensively. The aim is to summarize the fundamentals and mechanistic approaches in the preparation and characterization of metal colloidal nanoparticles and dispersions. In this way the reader is provided with a systematic and coherent picture of the interesting field of nanoscience based on noble metal colloidal nanoparticles. Intended as a wide-ranging overview, the book is a resource for novices in the field as well as for specialists, particularly those scientists working in the area of nanoparticle synthesis. Nanoscience and nanotechnology are discussed from the chemist’s point of view. Therefore, this volume describes in detail the terms, definitions, theories, experiments, and techniques dealing with the synthesis of noble metal nanoparticles. The material presented here is essential reading for research chemists, technologists, and engineers in the fields of specialty nanomaterials and metal industries, and also is highly valuable for researchers in university, institutional, and governmental laboratories, especially for those at advanced stages of their careers.
Biofunctionalization Of Nanomaterials
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Author : Challa S. S. R. Kumar
language : en
Publisher: Wiley-VCH
Release Date : 2005
Biofunctionalization Of Nanomaterials written by Challa S. S. R. Kumar and has been published by Wiley-VCH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Science categories.
Written by international experts describing the various facets of nanofabrication, the ten volumes of this series cover the complete range of synthetic methods, tools and techniques being developed towards medical, biological and cybernetic applications. This volume covers the synthetic and materials aspects of instilling biocompatibility into nanomaterials with properties desirable for advanced medical and biological applications.