Dna Repair And Mutagenesis
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Dna Repair And Mutagenesis
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Author : Errol C. Friedberg
language : en
Publisher: American Society for Microbiology Press
Release Date : 2005-11-22
Dna Repair And Mutagenesis written by Errol C. Friedberg and has been published by American Society for Microbiology Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-22 with Science categories.
An essential resource for all scientists researching cellular responses to DNA damage. • Introduces important new material reflective of the major changes and developments that have occurred in the field over the last decade. • Discussed the field within a strong historical framework, and all aspects of biological responses to DNA damage are detailed. • Provides information on covering sources and consequences of DNA damage; correcting altered bases in DNA: DNA repair; DNA damage tolerance and mutagenesis; regulatory responses to DNA damage in eukaryotes; and disease states associated with defective biological responses to DNA damage.
Dna Repair And Mutagenesis In Eukaryotes
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Author : W. Generoso
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Dna Repair And Mutagenesis In Eukaryotes written by W. Generoso and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Not many years ago most discussion of mutation induction by physical and chemical agents concentrated on the initial lesions induced in the DNA with the implicit assumption that once the lesions were made they were converted almost automatically to mutations by relatively simple processes associated with DNA replication. The discovery of a variety of enzymatic processes that can repair these lesions, the great increase in our understanding of the molecular steps involved in repair, replication, and recombination, and the increasing availability of cells with genetic defects in these pro cesses have led to the realization that mutation induction is a far more complex process than we originally thought. Repair systems can remove lesions before they can be converted to mutation, they can also convert initial lesions to secondary ones that are them selves mutagenic, and they can remove potentially lethal lesions at the expense of making mutations. The error-avoiding systems asso ciated with replication are themselves complex and may be caused to make mistakes in various ways. These different pathways for mutation production and mutation avoidance are still being worked out in prokaryotes and are less well understood in eukaryotes. This symposium shows, however, that very encouraging progress has been made in the last several years, and the progress is now accelerating.
Dna Repair And Mutagenesis
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Author : Errol C. Friedberg
language : en
Publisher:
Release Date : 1995
Dna Repair And Mutagenesis written by Errol C. Friedberg and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with DNA repair categories.
Dna Repair Mutagenesis And Other Responses To Dna Damage
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Author : Errol C. Friedberg
language : en
Publisher:
Release Date : 2014
Dna Repair Mutagenesis And Other Responses To Dna Damage written by Errol C. Friedberg and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Cellular control mechanisms categories.
Cellular DNA is constantly bombarded with environmental and chemical assaults that damage its molecular structure. In addition, the normal process of DNA replication is prone to error and may introduce mutations that can be passed to daughter cells. If left unrepaired, these DNA lesions can have serious consequences, such as cancer. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology reviews the mechanisms that cells use to recognize and repair various types of DNA damage. Contributors discuss base excision repair, nucleotide excision repair, mismatch repair, homologous recombination, nonhomologous end joining, the SOS response, and other pathways in prokaryotes and eukaryotes, and describe how these processes are linked to DNA replication, transcription, and cell cycle controls. The repair of telomeric and mitochondrial DNA is described, as is the influence of chromatin structure on DNA repair. This volume also includes discussion of human genetic diseases that involve defects in DNA damage repair. It is an essential reference for molecular and cell biologists, medical geneticists, cancer biologists, and all who want to understand how cells maintain genomic integrity.
Recent Research Development In Dna Repair And Mutagenesis
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Author : Encarna Alejandre-Durán
language : en
Publisher:
Release Date : 2002
Recent Research Development In Dna Repair And Mutagenesis written by Encarna Alejandre-Durán and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with DNA repair categories.
Dna Repair And Mutagenesis
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Author : Errol C. Friedberg
language : en
Publisher:
Release Date : 1995
Dna Repair And Mutagenesis written by Errol C. Friedberg and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Medical categories.
This is a major revision and updating of the classic work in the field of DNA repair by Errol Friedberg published in 1985. The authors have extensively revised the original text and provided more than 4000 references to current primary research literature. In addition, there are four new chapters on mutagenesis. The book will serve as an important reference resource for all courses in DNA repair and mutagenesis, and for molecular biologists working in many areas of cancer research.
Dna Repair And Mutagenesis
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Author :
language : en
Publisher:
Release Date : 2006
Dna Repair And Mutagenesis written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with DNA repair categories.
Completely reorganized, the new edition presents a significant overhaul of the existing chapters and introduces important new material, reflective of the major changes and developments that have occurred in the field over the last decade. As with the first edition, this new volume presents the field within a strong historical framework and all aspects of biological responses to DNA damage are detailed. The book consists of 30 chapters divided into five main parts, covering: sources and consequences of DNA damage; correcting altered bases in DNA: DNA repair; DNA damage tolerance and mutagenesis; regulatory responses to DNA damage in eukaryotes; and disease states associated with defective biological responses to DNA damage. Basic principles are appropriately stressed; however, the book focuses on the significant progress to date and future research directions.
Dna Repair And Mutagenesis In Eukaryotes
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Author : W. M. Generoso
language : en
Publisher:
Release Date : 1980
Dna Repair And Mutagenesis In Eukaryotes written by W. M. Generoso and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with categories.
Proceedings of the Symposium on DNA Repair and Mutagenesis in Eukaryotes, sponsored by the National Institute of Environmental Health Sciences, and held in Atlanta, Georgia, June 25-29, 1979.
Chemically Induced Dna Damage Mutagenesis And Cancer
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Author : Ashis K. Basu
language : en
Publisher: MDPI
Release Date : 2018-08-27
Chemically Induced Dna Damage Mutagenesis And Cancer written by Ashis K. Basu and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-27 with categories.
This book is a printed edition of the Special Issue " Chemically-Induced DNA Damage, Mutagenesis, and Cancer" that was published in IJMS
Dna Repair Mechanisms
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Author : Philip Hanawalt
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Dna Repair Mechanisms written by Philip Hanawalt and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
DNA Repair Mechanisms is an account of the proceedings at a major international conference on DNA Repair Mechanisms held at Keystone, Colorado on February 1978. The conference discusses through plenary sessions the overall standpoint of DNA repair. The papers presented and other important documents, such as short summaries by the workshop session conveners, comprise this book. The compilation describes the opposing views, those that agree and dispute about certain topic areas. This book, divided into 15 parts, is arranged according to the proceedings in the conference. The plenary sessions are grouped with the related workshop and poster manuscripts. The first two parts generally tackle repair in terms of its identification and quantification, as well as the models, systems, and perspectives it utilizes. The following parts discuss the various types of repair including base excision, nucleotide excision repair in bacteria, excision repair in mammalian cells, inducible/error-prone repair in prokaryotes, and strand break repair in mammalian cells among others. This reference material looks into the replicative bypass mechanisms in mammalian cells, viral probes, and hereditary repair defects. It explains repair deficiency and human disease, as well as mutagenesis and carcinogenesis. The last part of this book deals with the consequences and effects of DNA repair. This volume is a helpful source of reference for students, teachers, scientists, and researchers in the different fields of genetics, radiology, biochemistry, and environmental biology.