Drosophila Glia


Drosophila Glia
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Drosophila Glia


Drosophila Glia
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Author : LinFang Wang
language : en
Publisher: Biota Publishing
Release Date : 2019-03-18

Drosophila Glia written by LinFang Wang and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-18 with Science categories.


Glia, the non-neuronal cells in the nervous systems, are both passive and active participants in diverse arrays of neuronal function. The diversity of glial cells in various animal species appears to be correlated with the complexity of brains. In the animal Drosophila melanogaster, glia are similarly categorized to their mammalian counterparts in morphology and function. Surface glia cover the outermost surface of the brain and function as a blood-brain-barrier to protect the nervous system. Cortex glia, similar to mammalian astrocytes, enwrap around the neuronal cell bodies and provide trophic support. Neuropil glia, similar to mammalian astrocytes and oligodendrocytes, are closely associated with the synapse-enriched neuropils and regulate synapse formation, synaptic function, and underlie the mechanism of circuit and behavior. This short monograph focuses on Drosophila glia, discusses the classification of different glial subtypes and their developmental origins, and provides an overview of different glial-mediated activity crucial for the development and function of the nervous system. This context serves as a general introduction to the molecular and cellular basis of glial function in normal and pathological brains.



Neuron Glia Interrelations During Phylogeny I


Neuron Glia Interrelations During Phylogeny I
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Author : Antonia Vernadakis
language : en
Publisher: Springer Science & Business Media
Release Date : 1995-07-20

Neuron Glia Interrelations During Phylogeny I written by Antonia Vernadakis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-07-20 with Medical categories.


Leading international authorities report on their in vivo studies of neuron glia interactions in animals with simple nervous systems (insects, fish, amphibians, and reptiles). Their work amounts to an in-depth account of many of the principal functions of glial cells: myelination, regulation of ionic environment, neurotransmitter compartmentation and neurotransmitter receptors, blood brain barrier, regeneration, and aging. Part I examines the origin and role of glial cells during development across the phylogenetic spectrum, including the evolution of their particular functions. Part II discusses the physiological and metabolic interactions between neurons and glia, again across phylogenetic groups. Neuron Glia Interrelations During Phylogeny illuminates the evolution of the nervous system and expands our knowledge of the mechanisms involved in regeneration and central nervous system repair. It constitutes a virtual encyclopedia of up-to-date findings concerning the significant roles played by glial cells in neuronal development and function.



Neuron Glia Interrelations During Phylogeny


Neuron Glia Interrelations During Phylogeny
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Author : Antonia Vernadakis
language : en
Publisher: Springer Science & Business Media
Release Date : 1995-07-20

Neuron Glia Interrelations During Phylogeny written by Antonia Vernadakis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-07-20 with Medical categories.




The Functional Roles Of Glial Cells In Health And Disease


The Functional Roles Of Glial Cells In Health And Disease
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Author : Rebecca Matsas
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

The Functional Roles Of Glial Cells In Health And Disease written by Rebecca Matsas and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Thirty-five years ago, when Stephen Kuffler and his colleagues at Harvard initiated a new era of research on the properties and functions of neuroglial cells, very few neuro scientists were impressed at the time with the hypothesis that neuroglial cells could have another, though more subtle, role to play in the nervous system than to provide static support to neurons. Today, very few neuroscientists are unaware of the fact that multiple interactions between neurons and glial cells have been described, and that they consti tute the basis for understanding the function and the pathology of the nervous system. Glial cells outnumber neurons and make up about one-half of the bulk of the nervous system. They are divided into two major classes: first, the macroglia, which include astrocytes and oligodendrocytes in the central nervous system, and the Schwann cells in the peripheral nervous system; and second, the microglial cells. These different classes of glial cells have different functions and contribute in different ways in the devel opment, function, and the pathology of the nervous system.



Brain Development In Drosophila Melanogaster


Brain Development In Drosophila Melanogaster
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Author : Gerhard Martin Technau
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-01-08

Brain Development In Drosophila Melanogaster written by Gerhard Martin Technau and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-08 with Medical categories.


The fruitfly Drosophila melanogaster is an ideal model system to study processes of the central nervous system This book provides an overview of some major facets of recent research on Drosophila brain development.



Cellular And Molecular Control Of Collective Glial Cell Migration In Drosophilia


Cellular And Molecular Control Of Collective Glial Cell Migration In Drosophilia
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Author : Sara Berzsenyi
language : en
Publisher:
Release Date : 2010

Cellular And Molecular Control Of Collective Glial Cell Migration In Drosophilia written by Sara Berzsenyi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with categories.


A basic characteristic of many cell types in the body is their ability to move. The developing wing of the Drosophila provides an excellent model system to follow the behavior of the chain-migrating glial cells in vitro and in vivo by time-lapse microscopy. The glial cells are organized in a head-to-tail manner and move along the axons. With UV-ablation technique, I show that the pioneer cells at the migration front are required to promote chain migration from early stages on. By ablating cells in different combination at the front of the chain, I show that the first cell isolated from its neighbors cannot move and eventually dies. By increasing the number of cells in isolation, the functionality of the group of cells gradually becomes alike that of a control chain. These data indicate that integrity in collective glial movement might be realized through “community effect”, where a certain number of cells are required to assemble and form a migratory unit. During collective movement, cells are attached to each other via cell-cell adhesion. I show for the first time that N-cad is present in the peripheral glia of the Drosophila embryo and pupa. By overexpressing or downregulating N-cad specifically in the glial cells, I observe delay or acceleration, respectively, in completion of migration but the integrity of the chain remains intact. This suggests a role for N-cad in regulating the timing of glial movement. The downregulation of N-cad in the glia causes a mild decrease in the number of glia-glia adherens junctions, however, upon N-cad overexpression, Armadillo is recruited to the cell membrane.



Glial Cell Development


Glial Cell Development
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Author : Kristjan R. Jessen
language : en
Publisher:
Release Date : 2001

Glial Cell Development written by Kristjan R. Jessen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Medical categories.


The majority of cells in the nervous system are glial cells. During de velopment, these cells provide growth factors that stimulate the proli feration, migration and survival of neurones and their precursors, and promote and guide axonal growth. In the mature nervous system, glial cells provide insulating myelin sheath around axons and provide metabo lic and structural support for neurones. Glial cells also have a major influence on the local response to injury of central nerve tracts and the peripheral nervous system, either promoting, or inhibiting, axona l regrowth and recovery of lost function. This book provides a compreh ensive, state-of-the-art overview of research into the development, fu nction and malfunction of glial cells. It offers a compelling insight into how basic research throws light onto diseases and disorders and p oints the way towards treatments. Teams of internationally renowned ex perts, all active in research, have contributed chapters.



Glia


Glia
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Author : Ben Barres
language : en
Publisher: Cold Spring Harbor Perspective
Release Date : 2015

Glia written by Ben Barres and has been published by Cold Spring Harbor Perspective this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Medical categories.


The majority of cells in the nervous system are glia. Long thought of as passive bystanders, glial cells are increasingly being appreciated for their active roles in nourishing, supporting, and protecting the neuronal cells that relay electrical signals through the nervous system. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology examines the development of the major classes of glial cells-astrocytes, oligodendrocytes, Schwann cells, and microglia-and their roles in normal physiology and disease. The contributors describe how glia help establish and refine synaptic connections, maintain the metabolic and ionic milieu of nerve cells, myelinate axons, modulate nerve signal propagation, and contribute to the blood-brain barrier. The biological characteristics of glial cells in vertebrate and invertebrate model systems, including those of Drosophila, Caenorhabditis elegans, and zebrafish, are also covered. The authors also discuss the roles of glia in repair and regeneration, as well as in cancer and neurodegenerative diseases (e.g., Alzheimer's). This volume is therefore a valuable reference for all neurobiologists and biomedical scientists wishing to understand these diverse and dynamic cells.



Circadian Plasticity A Collaboration Between Neuronal And Glial Oscillators


Circadian Plasticity A Collaboration Between Neuronal And Glial Oscillators
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Author : Jolanta Górska-Andrzejak
language : en
Publisher: Frontiers Media SA
Release Date : 2019-10-24

Circadian Plasticity A Collaboration Between Neuronal And Glial Oscillators written by Jolanta Górska-Andrzejak and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-24 with categories.




Comprehensive Developmental Neuroscience Patterning And Cell Type Specification In The Developing Cns And Pns


Comprehensive Developmental Neuroscience Patterning And Cell Type Specification In The Developing Cns And Pns
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Author : T. Stork
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-05-06

Comprehensive Developmental Neuroscience Patterning And Cell Type Specification In The Developing Cns And Pns written by T. Stork and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-06 with Medical categories.