Drug Class Review On Targeted Immune Modulators
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Drug Class Review On Targeted Immune Modulators
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Author : Gerald Gartlehner
language : en
Publisher:
Release Date : 2006
Drug Class Review On Targeted Immune Modulators written by Gerald Gartlehner and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.
Targeted immune modulators are used in the treatment of certain types of immunologic and inflammatory diseases, including rheumatoid arthritis, juvenile rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, plaque psoriasis, Crohn's disease, and ulcerative colitis. These drugs work by selectively blocking mechanisms involved in the inflammatory and immune response. The purpose of this review is to help policy makers and clinicians make informed choices about the use of targeted immune modulators.
Drug Class Review On Targeted Immune Modulators
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Author : Gerald Gartlehner
language : en
Publisher:
Release Date : 2005
Drug Class Review On Targeted Immune Modulators written by Gerald Gartlehner and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Biological response modifiers categories.
Targeted immune modulators are used in the treatment of certain types of immunologic and inflammatory diseases, including rheumatoid arthritis, juvenile rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, plaque psoriasis, Crohn's disease, and ulcerative colitis. These drugs work by selectively blocking mechanisms involved in the inflammatory and immune response. The purpose of this review is to help policy makers and clinicians make informed choices about the use of targeted immune modulators.
Drug Class Review
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Author : Gerald Gartlehner
language : en
Publisher:
Release Date : 2009
Drug Class Review written by Gerald Gartlehner and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Biological response modifiers categories.
Drug Class Review
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Author :
language : en
Publisher:
Release Date : 2012
Drug Class Review written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.
PURPOSE: We systematically compared the efficacy, effectiveness, and safety (adverse events) of abatacept, adalimumab, alefacept, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, natalizumab, rituximab, tocilizumab, and ustekinumab in patients with rheumatoid arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, psoriatic arthritis, Crohn's disease, ulcerative colitis, and plaque psoriasis. DATA SOURCES: To identify published studies, we searched PubMed, EMBASE, CINAHL, Centre for Reviews and Dissemination, The Cochrane Library, and International Pharmaceutical Abstracts from 2009 (January) to 2011 (October). We also searched the US Food and Drug Administration Center for Drug Evaluation and Research website for additional unpublished data, requested dossiers of information from pharmaceutical manufacturers, and retrieved relevant citations from reference lists of included studies. REVIEW METHODS: Study selection, data abstraction, validity assessment, grading the strength of the evidence, and data synthesis were all carried out according to our standard review methods. RESULTS AND CONCLUSION: Overall, targeted immune modulators are highly effective medications for the treatment of rheumatoid arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, psoriatic arthritis, Crohn's disease, ulcerative colitis, and plaque psoriasis that substantially improve the burden of disease and are generally safe for short-term treatment. For rheumatoid arthritis, low-and moderate-strength evidence indicated that some targeted immune modulators are more efficacious than others. These results were based on three head-to-head trials, several large observational studies, and indirect comparisons of placebo-controlled trials. The evidence is currently insufficient to reliably determine the comparative effectiveness for other indications and in subgroups. Low-strength evidence indicated that serious infections are less common with abatacept than the other drugs and that the rate of adverse events is greater with infliximab than adalimumab or etanercept. Likewise, more patients receiving infliximab withdrew due to adverse events than abatacept, adalimumab, etanercept, and golimumab. Infusion or allergic reactions contributed to the difference in risk.
Oregon S Drug Review
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Author :
language : en
Publisher:
Release Date : 2006
Oregon S Drug Review written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Biological response modifiers categories.
Targeted Immune Modulators
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Author :
language : en
Publisher:
Release Date : 2009
Targeted Immune Modulators written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Biological response modifiers categories.
Targeted Immune Modulators
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Author : Gerald Gartlehner
language : en
Publisher:
Release Date : 2007
Targeted Immune Modulators written by Gerald Gartlehner and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Antirheumatic agents categories.
Adverse Events With Biomedicines
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Author : Giuseppe Tridente
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-12-09
Adverse Events With Biomedicines written by Giuseppe Tridente and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-09 with Medical categories.
This monograph gathers and evaluates data on adverse events (AEs) associated specifically with those “biomedicines” – monoclonal antibodies, fusion proteins, and cytokines – that have recently entered therapeutic use in humans. All AEs observed when using each member of this new drug class are covered, with a view to improving understanding of pathogenesis, facilitating prevention, monitoring, and control, and contributing to the development of better drugs that provide benefits while minimizing risk. Further aspects here examined include the role of drug mechanisms of action and immunogenicity in relation to AEs outcome and induction of systemic syndromes. Additional data on AEs in off-label treatments are also considered. Electronic data sheets, downloadable from Springer Extra Materials platform, include more detailed safety data as well as additional basic information on product characteristics, pre- and post-marketing AEs classified according to frequency, and system/organ targeting. Data on excipients and selected information on drug interactions and associations are also provided. Adverse Events with Biomedicines: Prevention Through Understanding will serve as a detailed, practical guideline to this important new area, which demands the attention of clinicians, immunologists, oncologists, allergologists, public health professionals, and drug companies.
Moderate To Severe Psoriasis Fourth Edition
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Author : John Y. M. Koo
language : en
Publisher: CRC Press
Release Date : 2014-03-18
Moderate To Severe Psoriasis Fourth Edition written by John Y. M. Koo and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-18 with Medical categories.
Written by experts in the dermatology field, this new fourth edition of Moderate-to-Severe Psoriasis discusses the current use of biologics and other pharmacologic and phototherapy treatments for moderate-to-severe psoriasis. Illustrated with high quality color figures, this standalone text emphasizes safe and effective treatments for the psoriasis patient that are perfect for the dermatologist in daily practice. New to this edition are chapters on day treatment programs, new agents, erythrodermic and pustular psoriasis, special populations, and pharmacogenetics.
Scully S Medical Problems In Dentistry E Book
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Author : Crispian Scully
language : en
Publisher: Elsevier Health Sciences
Release Date : 2014-07-21
Scully S Medical Problems In Dentistry E Book written by Crispian Scully and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-21 with Medical categories.
This text offers an authoritative account of general medical and surgical conditions as they apply to the practice of dentistry and oral healthcare. Now established as the standard reference on the subject, Medical Problems in Dentistry is essential for students learning for the first time or practitioners needing to keep up-to-date with their knowledge. Detailed coverage outlines the complete relevance of systemic diseases and their treatment to dentistry – essential knowledge for the whole dental team User-friendly format allows ease of access to information whether for exam revision purposes or for a specific issue confronting staff in a busy clinical environment Clearly written with excellent use of illustrations, the book is an essential, easy to use, reliable source of information Text completely updated and re-organised to increase focus on the more dentally-relevant aspects of medicine and subject areas that have undergone recent change Entries more fully alphabetized to improve access to information Accompanying ‘key points boxes’ highlight the most crucial aspects of specific medical conditions Content peer-reviewed by a specialist Advisory Board to ensure accuracy of information and the inclusion of the latest advances Additional coverage of autoinflammatory disorders, biological response modifiers, craniofacial transplantation, drug reactions, drug-resistant microbial infections, osteonecrosis, and immune reconstitution syndrome Completely new entries such as alternative and complementary medicine, health promotion, men’s issues and occupational health New national and international guidelines, selected recent references and up-to-date websites