Drug Delivery And Targeting
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Drug Delivery And Targeting
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Author : Anya M. Hillery
language : en
Publisher: CRC Press
Release Date : 2003-09-02
Drug Delivery And Targeting written by Anya M. Hillery and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-02 with Medical categories.
The advances in biotechnology and molecular biology over recent years have resulted in a large number of novel molecules with the potential to revolutionize the treatment and prevention of disease. However, such potential is severely compromised by significant obstacles to delivery of these drugs in vivo. These obstacles are often so great that effective drug delivery and targeting is now recognized as the key to effective development of many therapeutics. Advanced drug delivery and targeting can offer significant advantages to conventional drugs, such as increased efficiency, convenience, and the potential for line extensions and market expansion. An accessible and easy-to-read textbook, Drug Delivery and Targeting for Pharmacists and Pharmaceutical Scientists is the first book to provide a comprehensive introduction to the principles of advanced drug delivery and targeting, their current applications and potential future developments, including: *Methods to optimize therapeutic efficacy, and the related commercial implications *Difficulties with drug absorption, unwanted distribution and premature inactivation / elimination *Attempts to minimize toxicity or alter immunogenicity *Methods to achieve rate-controlled drug release and effective drug targeting *Novel and established routes of delivery *Use of new generation technologies such as biosensors, microchips, stimuli-sensitive hydrogels and plasmid-based gene therapy This volume is indispensable for pharmaceutical students, scientists and researchers.
Targeted Drug Delivery Concepts And Design
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Author : Padma V. Devarajan
language : en
Publisher: Springer
Release Date : 2014-12-08
Targeted Drug Delivery Concepts And Design written by Padma V. Devarajan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-08 with Medical categories.
This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active targeting strategies, and various advanced drug delivery tools such as functionalized lipidic, polymeric and inorganic nanocarriers. Together, the twenty-three chapters cover a wide range of topics in the field, including tumor and hepatic targeting, polymer-drug conjugates, nanoemulsion, physical and biophysical characteristics of nanoparticles, and in vivo imaging techniques, among others. The book also examines advanced characterization techniques, regulatory hurdles and toxicity-related issues that are key features for successful commercialization of targeted drug delivery system products. Targeted Drug Delivery is a comprehensive reference guide for drug delivery researchers, both beginners and those already working in the field.
Drug Targeting And Stimuli Sensitive Drug Delivery Systems
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Author : Alexandru Mihai Grumezescu
language : en
Publisher: William Andrew
Release Date : 2018-05-21
Drug Targeting And Stimuli Sensitive Drug Delivery Systems written by Alexandru Mihai Grumezescu and has been published by William Andrew this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-21 with Science categories.
Drug Targeting and Stimuli Sensitive Drug Delivery Systems covers recent advances in the area of stimuli sensitive drug delivery systems, providing an up-to-date overview of the physical, chemical, biological and multistimuli-responsive nanosystems. In addition, the book presents an analysis of clinical status for different types of nanoplatforms. Written by an internationally diverse group of researchers, it is an important reference resource for both biomaterials scientists and those working in the pharmaceutical industry who are looking to help create more effective drug delivery systems. Shows how the use of nanomaterials can help target a drug to specific tissues and cells Explores the development of stimuli-responsive drug delivery systems Includes case studies to showcase how stimuli responsive nanosystems are used in a variety of therapies, including camptothecin delivery, diabetes and cancer therapy
Fasttrack Pharmaceutics
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Author : Yvonne Perrie
language : en
Publisher: Pharmaceutical Press
Release Date : 2012
Fasttrack Pharmaceutics written by Yvonne Perrie and has been published by Pharmaceutical Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
"Pharmaceutics - Drug delivery and targeting focuses on what pharmacy students really need to know in order to pass exams, providing concise, bulleted information, key points, tips and an all-important self-assessment section which includes MCQs."--Page 4 of cover.
Brain Targeted Drug Delivery Systems
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Author : Huile Gao
language : en
Publisher: Academic Press
Release Date : 2018-09-20
Brain Targeted Drug Delivery Systems written by Huile Gao and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-20 with Medical categories.
Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems. As the brain is the most important organ in the human body, and disorders of the central nervous system (CNS) are the most serious threat to human life, this book highlights advances and new research in drug delivery methods to the brain. Provides an overview of brain targeting drug delivery that is useful to both academic and industry-based researchers Discusses key points in developing brain targeting drug delivery systems Summarizes and presents currently available strategies for brain targeting drug delivery Covers not only current studies and their strengths, but also gives insight into the pitfalls of current research
Targeted Drug Delivery
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Author : Rachael W. Sirianni
language : en
Publisher: Humana Press
Release Date : 2018-07-27
Targeted Drug Delivery written by Rachael W. Sirianni and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-27 with Medical categories.
This volume looks at the latest techniques used to enable therapeutic molecules to be targeted for site-specific delivery. The chapters in this book discuss topics such as approaches to express biologically derived and synthetic nanocarriers; strategies to assist in nanocarrier targeting to specific cells and tissues; and methods for evaluating delivery and efficiency for new classes of agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Targeted Drug Delivery: Methods and Protocols is a valuable resource for anyone interested in understanding the diversity of methods used in this evolving field.
Drug Delivery And Targeting
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Author : Monika Schäfer-Korting
language : en
Publisher: Springer Nature
Release Date :
Drug Delivery And Targeting written by Monika Schäfer-Korting and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Smart Drug Delivery System
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Author : Ali Demir Sezer
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-02-10
Smart Drug Delivery System written by Ali Demir Sezer and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-10 with Medical categories.
This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different smart drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, diabetic, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.
Lipid Nanocarriers For Drug Targeting
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Author : Alexandru Mihai Grumezescu
language : en
Publisher: William Andrew
Release Date : 2018-04-16
Lipid Nanocarriers For Drug Targeting written by Alexandru Mihai Grumezescu and has been published by William Andrew this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-16 with Science categories.
Lipid Nanocarriers for Drug Targeting presents recent advances in the area of lipid nanocarriers. The book focuses on cationic lipid nanocarriers, solid lipid nanocarriers, liposomes, thermosensitive vesicles, and cubosomes, with applications in phototherapy, cosmetic and others. As the first book related to lipid nanocarriers and their direct implication in pharmaceutical nanotechnology, this important reference resource is ideal for biomaterials scientists and those working in the medical and pharmaceutical industries that want to learn more on how lipids can be used to create more effective drug delivery systems. Highlights the most commonly used types of lipid nanocarriers and explains how they are applied in pharmacy Shows how lipid nanocarriers are used in different types of treatment, including oral medicine, skin repair and cancer treatment Assesses the pros and cons of using different lipid nanocarriers for different therapies
Drug Delivery
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Author : Anya M Hillery
language : en
Publisher: CRC Press
Release Date : 2016-09-15
Drug Delivery written by Anya M Hillery and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-15 with Medical categories.
This book provides a comprehensive introduction to advanced drug delivery and targeting, covering their principles, current applications, and potential future developments. This edition has been updated to reflect significant trends and cutting-edge advances that have occurred since the first edition was published. All the original chapters have been retained, but the material therein has been updated. Eight new chapters have been added that deal with entirely new technologies and approaches. Features: Offers a comprehensive introduction to the fundamental concepts and underlying scientific principles of drug delivery and targeting Presents an in-depth analysis of the opportunities and obstacles afforded by the application of nanotechnologies for drug delivery and targeting Includes a revised and expanded section on the major epithelial routes of drug delivery currently under investigation Describes the most recent, emerging, and innovative technologies of drug delivery Provides real-life examples of the clinical translation of drug delivery technologies through the use of case studies Discusses the pertinent regulatory hurdles and safety issues of drug delivery and targeting systems—crucial considerations in order to achieve licensing approval for these new technologies