Drug Discovery And Development Explained Introductory Notes For The General Public
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Drug Discovery And Development Explained Introductory Notes For The General Public
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Author : Bruno Villoutreix
language : en
Publisher: Frontiers Media SA
Release Date : 2024-12-11
Drug Discovery And Development Explained Introductory Notes For The General Public written by Bruno Villoutreix and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-11 with Medical categories.
Drug discovery and development involve complex processes, highly integrated interdisciplinary research, and collaborations between academic groups and the private sector. It is a long and resource-intensive endeavor characterized by a high attrition rate. Yet new strategies are being explored, aiming at accelerating the development of novel treatments, from the combination of artificial intelligence with cutting-edge experimental approaches, and the development of novel types of therapeutic agents to personalized medicine. Because drug discovery and development is a vast field with many stakeholders and potential conflicts of interest, it is important that the general public gains basic knowledge about the main concepts to be able to make informed healthcare decisions for themselves and family members, understand discussions in the news and social networks or proposals from policymakers and politicians. Furthermore, people are directly affected by the field, as patients seeking novel and better treatments, as volunteers in clinical trials, or as members of patient organizations. Building public knowledge and understanding about the field of drug discovery and development will also help to address growing public concerns about how health data should be collected and used.
Introduction To Biological And Small Molecule Drug Research And Development
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Author : C. Robin Ganellin
language : en
Publisher: Academic Press
Release Date : 2013-05-07
Introduction To Biological And Small Molecule Drug Research And Development written by C. Robin Ganellin and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-07 with Science categories.
Introduction to Biological and Small Molecule Drug Research and Development provides, for the first time, an introduction to the science behind successful pharmaceutical research and development programs. The book explains basic principles, then compares and contrasts approaches to both biopharmaceuticals (proteins) and small molecule drugs, presenting an overview of the business and management issues of these approaches. The latter part of the book provides carefully selected real-life case studies illustrating how the theory presented in the first part of the book is actually put into practice. Studies include Herceptin/T-DM1, erythropoietin (Epogen/Eprex/NeoRecormon), anti-HIV protease inhibitor Darunavir, and more. Introduction to Biological and Small Molecule Drug Research and Development is intended for late-stage undergraduates or postgraduates studying chemistry (at the biology interface), biochemistry, medicine, pharmacy, medicine, or allied subjects. The book is also useful in a wide variety of science degree courses, in post-graduate taught material (Masters and PhD), and as basic background reading for scientists in the pharmaceutical industry. - For the first time, the fundamental scientific principles of biopharmaceuticals and small molecule chemotherapeutics are discussed side-by-side at a basic level - Edited by three senior scientists with over 100 years of experience in drug research who have compiled the best scientific comparison of small molecule and biopharmaceuticals approaches to new drugs - Illustrated with key examples of important drugs that exemplify the basic principles of pharmaceutical drug research and development
Introduction To Pharmaceutical Technology Development
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Author : Yaser Dahman
language : en
Publisher: Elsevier
Release Date : 2025-02-24
Introduction To Pharmaceutical Technology Development written by Yaser Dahman and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-24 with Medical categories.
Introduction to Pharmaceutical Technology Development: Journey from Lab to Shelf of Commercial Pharmaceutical Drugs is a complete reference and learning resource for those working in pharmaceutics or aspiring to join the industry. The book provides a comprehensive view into all aspects of drug discovery, approval, and production. Using examples of well-known drugs and their journeys from lab to market, the book provides a comprehensive overview of all steps involved in bringing new drugs, including biologics, to the shelves.Topics covered include Drug Discovery, Pharmaceutical Formulations of Different Dose Form, Analytical Testing and Development, Unit Operations and Design for Major Equipment, Basics of Analytics and Process Validations and Protocols (DQ, IQ, OQ, PQ) in FDA-Regulated Industries.This book provides graduate students from several areas with a solid foundation of the Pharmaceutic industry across key stages on new drug lifecycle. - Provides readers with introductory information on the developments in pharmaceutical technology - Includes complete coverage of equipment and unit operations relevant across the production cycle of drugs - Illustrates the path to commercialization through studies on the journey of several common commercially available formulated medications
Multidisciplinary Approach In Research Area Volume 9
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Author : Chief Editor- Biplab Auddya, Editor- Dr.M.Muthulakshmi, Viswaraju Udayabhaskar, Dr. Devimeenakshi.k., Dr. Haribhau Mahipati Borate, Ms.Saswati Jena, V Geetha
language : en
Publisher: The Hill Publication
Release Date : 2024-04-17
Multidisciplinary Approach In Research Area Volume 9 written by Chief Editor- Biplab Auddya, Editor- Dr.M.Muthulakshmi, Viswaraju Udayabhaskar, Dr. Devimeenakshi.k., Dr. Haribhau Mahipati Borate, Ms.Saswati Jena, V Geetha and has been published by The Hill Publication this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-17 with Antiques & Collectibles categories.
Drug Discovery And Development E Book
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Author : Raymond G Hill
language : en
Publisher: Elsevier Health Sciences
Release Date : 2021-05-16
Drug Discovery And Development E Book written by Raymond G Hill and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-16 with Medical categories.
With unprecedented interest in the power that the modern therapeutic armamentarium has to combat disease, the new edition of Drug Discovery and Development is an essential resource for anyone interested in understanding how drugs and other therapeutic interventions are discovered and developed, through to clinical research, registration, and market access. The text has been thoroughly updated, with new information on biopharmaceuticals and vaccines as well as clinical development and target identification. Drug discovery and development continues to evolve rapidly and this new edition reflects important changes in the landscape. Edited by industry experts Raymond Hill and Duncan Richards, this market-leading text is suitable for undergraduates and graduates undertaking degrees in pharmacy, pharmacology, toxicology, and clinical development through to those embarking on a career in the pharmaceutical industry. - Key stages of drug discovery and development - Chapters outline the contribution of individual disciplines to the overall process - Supplemented by specific chapters on different modalities - Includes coverage of Oligonucleotide therapies; cell and gene therapy - Now comes with online access on StudentConsult
Prescription Drugs
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Author : David E. Newton
language : en
Publisher: Bloomsbury Publishing USA
Release Date : 2021-11-12
Prescription Drugs written by David E. Newton and has been published by Bloomsbury Publishing USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-12 with Medical categories.
Prescription drugs are a basic and invaluable part of society today, but there is debate surrounding the methods of testing new drugs, the possible misuse of prescription drugs, and the economics of drug production and use. This book examines the evolution of prescription drugs in the United States, as well as the formation of the pharmaceutical industry. It begins with a history of prescription drugs, dating back to their origins, then moves through the Industrial Revolution and into the present day. It also delves into the issues and controversies related to prescription drugs, such as drug costs, regulations, prescription drug abuse, insurance complications, and more. Both implemented and proposed solutions are also discussed. One of the most valuable aspects of the book is that it surveys the history of prescription drugs in a manner that helps the reader identify key issues in an easy-to-understand fashion. Finally, the perspectives chapter allows a broad range of voices to be heard, allowing crucial, diverse perspectives to round out the author's expertise.
Biocapital
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Author : Kaushik Sunder Rajan
language : en
Publisher: Duke University Press
Release Date : 2006-04-24
Biocapital written by Kaushik Sunder Rajan and has been published by Duke University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-24 with Business & Economics categories.
Biocapital is a major theoretical contribution to science studies and political economy. Grounding his analysis in a multi-sited ethnography of genomic research and drug development marketplaces in the United States and India, Kaushik Sunder Rajan argues that contemporary biotechnologies such as genomics can only be understood in relation to the economic markets within which they emerge. Sunder Rajan conducted fieldwork in biotechnology labs and in small start-up companies in the United States (mostly in the San Francisco Bay area) and India (mainly in New Delhi, Hyderabad, and Bombay) over a five-year period spanning 1999 to 2004. He draws on his research with scientists, entrepreneurs, venture capitalists, and policymakers to compare drug development in the two countries, examining the practices and goals of research, the financing mechanisms, the relevant government regulations, and the hype and marketing surrounding promising new technologies. In the process, he illuminates the global flow of ideas, information, capital, and people connected to biotech initiatives. Sunder Rajan’s ethnography informs his theoretically sophisticated inquiry into how the contemporary world is shaped by the marriage of biotechnology and market forces, by what he calls technoscientific capitalism. Bringing Marxian theories of value into conversation with Foucaultian notions of biopolitics, he traces how the life sciences came to be significant producers of both economic and epistemic value in the late twentieth century and early twenty-first.
U S Industry In 2000
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 1999-05-11
U S Industry In 2000 written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-05-11 with Political Science categories.
U.S. industry faced a gloomy outlook in the late 1980s. Then, industrial performance improved dramatically through the 1990s and appears pervasively brighter today. A look at any group of industries, however, reveals important differences in the factors behind the resurgenceâ€"in industry structure and strategy, research performance, and location of activitiesâ€"as well as similarities in the national policy environment, impact of information technology, and other factors. U.S. Industry in 2000 examines eleven key manufacturing and service industries and explores how they arrived at the present and what they face in the future. It assesses changing practices in research and innovation, technology adoption, and international operations. Industry analyses shed light on how science and technology are applied in the marketplace, how workers fare as jobs require greater knowledge, and how U.S. firms responded to their chief competitors in Europe and Asia. The book will be important to a wide range of readers with a stake in U.S. industrial performance: corporate executives, investors, labor representatives, faculty and students in business and economics, and public policymakers.
Tuberculosis Drug Discovery And Development 2019
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Author : Giovanna Riccardi
language : en
Publisher: MDPI
Release Date : 2020-11-24
Tuberculosis Drug Discovery And Development 2019 written by Giovanna Riccardi and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-24 with Science categories.
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis and still represents one of the global health threats to mankind. The World Health Organization estimated more than 10 million new cases and reported more than 1.5 million deaths in 2019, thus ranking TB among the main causes of death due to a single pathogen. Standard anti-TB therapy includes four first-line antibiotics that should be administered for at least six months. However, in the case of multi- and extensively drug-resistant TB, second-line medications must be used and these frequently cause severe side effects resulting in poor compliance. Developing new anti-TB drug candidates is therefore of outmost importance. In this Special Issue dedicated to Tuberculosis Drug Discovery and Development, we present the main and latest achievements in the fields of drug and target discovery, host-directed therapy, anti-virulence drugs, and describe the development of two advanced compounds: macozinone and delpazolid. In addition, this Special Issue provides an historical perspective focused on Carlo Forlanini, the inventor of pneumothorax for TB treatment, and includes an overview of the state-of-the-art technologies which are being exploited nowadays in TB drug development. Finally, a summary of TB vaccines that are either approved or undergoing clinical trials concludes the Special Issue.
Science Technology And The Economy
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Author : Proceedings of the National Academy of Sciences
language : en
Publisher: National Academies Press
Release Date : 1996-01-01
Science Technology And The Economy written by Proceedings of the National Academy of Sciences and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-01-01 with Business & Economics categories.