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Drug Interactions In Infectious Diseases


Drug Interactions In Infectious Diseases
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Drug Interactions In Infectious Diseases


Drug Interactions In Infectious Diseases
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Author : Stephen C. Piscitelli
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-28

Drug Interactions In Infectious Diseases written by Stephen C. Piscitelli and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-28 with Medical categories.


Over the past 25 years, the world’s population has witnessed an explosion in kno- edge about infectious diseases. The global population is coming to the realization that diseases long recognized to cause substantial suffering, such as malaria, tuberculosis, schistosomiasis, and hepatitis, can be diagnosed and treated, and that transmission can be prevented using tools that are available, and which may be becoming increasingly affordable. The global population is recognizing that few infections are local: the travel of humans, other animals, insects, and food transport pathogens around the world, often with astonishing rapidity. New pathogens are appearing, either newly recognized or newly developing, such as severe acute respiratory syndrome (SARS), avian inf- enza, metapneumovirus, or hepatitis C, which are causing human morbidity and m- tality. Finally, there is growing fear that dangerous pathogens may be intentionally introduced into human populations by deranged individuals or terrorist organizations. The potential to use drugs or biologic agents to treat and prevent infectious diseases has increased dramatically over the past quarter century as we have learned more about the biology of many of these agents, and as we have developed techniques to discover new agents by high throughput screening programs and by sophisticated drug design and synthesis.



Drug Interactions In Infectious Diseases Mechanisms And Models Of Drug Interactions


Drug Interactions In Infectious Diseases Mechanisms And Models Of Drug Interactions
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Author : Manjunath P. Pai
language : en
Publisher: Springer
Release Date : 2018-03-05

Drug Interactions In Infectious Diseases Mechanisms And Models Of Drug Interactions written by Manjunath P. Pai and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-05 with Medical categories.


The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes – “Mechanisms and Models of Drug Interactions” and “Antimicrobial Drug Interactions”. This volume, “Mechanisms and Models of Drug Interactions,” delivers a text that enhances clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The book provides a comprehensive review of basic clinical pharmacology with a focus on metabolism and transporter-mediated drug interactions. The chapters address materials that cannot be retrieved easily in the medical literature, including materials focused on the complex interrelationship of acute infection, inflammation, and the risk of drug interactions in the Drug-Cytokine chapter. The Food-Drug and Herb-Drug interactions chapters remain definitive resources. A new chapter on in vitro modeling of drug interactions is included along with updates on design and data analysis of clinical drug interaction studies. Authoritative discussion of models for regulatory decision-making on drug-drug interactions provides the necessary framework to aid antimicrobial drug development. This concise review of the mechanisms and models of drug interactions provides important insights to health care practitioners as well as scientists in drug development.



Drug Interactions In Infectious Diseases Antimicrobial Drug Interactions


Drug Interactions In Infectious Diseases Antimicrobial Drug Interactions
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Author : Manjunath P. Pai
language : en
Publisher: Springer
Release Date : 2018-03-19

Drug Interactions In Infectious Diseases Antimicrobial Drug Interactions written by Manjunath P. Pai and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-19 with Medical categories.


The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes – “Mechanisms and Models of Drug Interactions” and “Antimicrobial Drug Interactions”. This volume, “Antimicrobial Drug Interactions,” delivers a quick clinical resource that distills relevant drug interactions by antimicrobial drug class. The book provides informative tables on specific drug-drug interactions that include the degree and severity of the expected interaction. A mechanistic basis for drug-drug interactions is also provided to link observed interactions to pharmacologic characteristics of key drug classes. This complete resource is organized by major antibacterial, antimycobacterial, antiviral, antifungal, antimalarial, and antiprotozoal class. In line with current innovations in antimicrobial drug development, a distinct chapter on the pharmacologic management of drug interactions in hepatitis B virus (HBV) and hepatitis C virus (HCV)-related infections is included. Two new chapters are dedicated to the management of human immunodeficiency virus (HIV) drug-drug interactions given the breadth of antiretroviral class-specific effects. This comprehensive review of known drug interactions and strategies to manage them is an invaluable resource to all health care practitioners.



Clinical Use Of Anti Infective Agents


Clinical Use Of Anti Infective Agents
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Author : Robert W. Finberg
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-01-16

Clinical Use Of Anti Infective Agents written by Robert W. Finberg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-16 with Medical categories.


This book was designed as a reference tool for pharmacists involved in the treatment of patients with infections. It is clinically oriented and designed to help students in all medical disciplines, and especially pharmacists and students of pharmacy who need information on choosing the correct drug, dose, and method of administration of an agent to patients with infectious diseases. Nurse practitioners and clinical microbiologists who need to understand the use of anti-infective agents in patients will also find this volume useful.



Pharmacokinetic And Pharmacodynamic Drug Interactions Associated With Antiretroviral Drugs


Pharmacokinetic And Pharmacodynamic Drug Interactions Associated With Antiretroviral Drugs
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Author : Tony K. L. Kiang
language : en
Publisher: Springer
Release Date : 2016-12-21

Pharmacokinetic And Pharmacodynamic Drug Interactions Associated With Antiretroviral Drugs written by Tony K. L. Kiang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-21 with Medical categories.


Clinically-focussed, with easily accessible tables and chapter summaries suitable for clinicians and researchers, this comprehensive book provides a systematic, critical evaluation of the current literature. An updated clinical decision-making algorithm specifically tailored to the antiretroviral drugs is also provided. The identified interactions are interpreted in the context of known mechanisms derived from clinical, preclinical, and in vitro data. The clinical relevance of the interactions is systematically evaluated and gaps in literature discussed in the context of potential future experiments. In addition to the comprehensive summary of pharmacokinetic and pharmacodynamic drug interactions associated with WHO-recommended antiretroviral drugs on the market today (i.e. nucleotide reverse-transcriptase inhibitors, non-nucleoside reverse-transcriptase inhibitors, integrase inhibitors, and protease inhibitors), this book also provides detailed section summaries on the epidemiology of HIV infection, diagnosis and pharmacotherapy, basic pharmacology of the individual antiretrovirals, pertinent pre-clinical and in vitro molecular pharmacology, and in vitro drug interaction data available in the literature today.



Hiv Drug Interaction Guide Ddi


Hiv Drug Interaction Guide Ddi
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Author : Paul A. Pham
language : en
Publisher: Knowledge Source Solutions
Release Date : 2012-04-27

Hiv Drug Interaction Guide Ddi written by Paul A. Pham and has been published by Knowledge Source Solutions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-27 with categories.


Debuting the 2012 DDI Guide; the definitive reference for ARV Drug Interactions. This resource uses full color charts to cross-reference all ARV's with hundreds of commonly prescribed concomitant medications. The management of HIV infection is rapidly evolving and becoming increasingly complex. In many cases, the medication profile of patients is extensive and complex. As a result, there is a high potential for clinically significant drug interaction. Computerized pharmacy systems can detect some drug-drug interactions and decrease the number of inappropriate prescriptions. However, a limitation of such system is the inability to update the information beyond the FDA approved labeling. The goal of this book is to present a practical approach to the management of drug interactions to clinicians caring for HIV-infected patients. Also, since many drug combinations have not been formally studied, the authors attempt to predict potential drug interaction based on pharmacologic principle



Manual Of Antibiotics And Infectious Diseases


Manual Of Antibiotics And Infectious Diseases
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Author : John E. Conte
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2002

Manual Of Antibiotics And Infectious Diseases written by John E. Conte and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.


This book covers antibiotics currently available, their doses, and their dose adjustments. It explains what to do when faced with renal failure, as well as empirical, prophylactic, and definitive antibiotic therapies--everything from bacteria resistance to AIDS therapies. (Midwest).



Drug Interactions In Infectious Diseases


Drug Interactions In Infectious Diseases
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Author : Stephen C. Piscitelli
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-09-08

Drug Interactions In Infectious Diseases written by Stephen C. Piscitelli and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-08 with Medical categories.


The revised and up-to-date third edition of Drug Interactions in Infectious Diseases delivers a text that will enhance your clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The third edition features five new chapters that cover material not addressed in previous editions. These new chapters describe interactions with a number of drug classes such as non-HIV antiviral, antimalarial, antiparasitic, antihelmintic, macrolide, azalide and ketolide agents. A novel chapter on probe cocktail studies has been included to highlight an important research tool for drug development. These chapters address material that cannot be retrieved easily in the medical literature. The highly acclaimed food-drug interactions as well as the study design and analysis chapters remain definitive references. The newly written drug-cytokine interaction highlights the need for our improved understanding of the complex interrelationship of acute infection, inflammation, and the risk of drug interactions. Informative tables on specific drug-drug interactions are provided throughout the chapters as a quick clinical resource. The Third Edition of Drug Interactions in Infectious Diseases is a distillation of relevant drug interactions associated with antimicrobials, infection, and inflammation. This concise review of the mechanisms and strategies to manage drug interactions should be valuable to all health care practitioners. Features • Definitive reference source of up-to-date information on antimicrobial drug interactions • Informative tables on the degree of interaction for specific antimicrobial agents • In-depth discussion of mechanisms and potential mechanistic pathways of interaction • New chapters on non-HIV antiviral, antimalarial, antiparasitic, and macrolide, azalide and ketolide agents • New chapter on probe-cocktail studies as a research tool to study drug-drug interactions • Inclusion of new antimicrobial agents and their associated drug interactions • First rate chapters on study design and analysis, and drug-food interactions • A fresh perspective on drug-cytokine interactions • Authoritative chapter on regulatory considerations of drug interactions during drug development



Drug Therapy For Infectious Diseases Of The Dog And Cat


Drug Therapy For Infectious Diseases Of The Dog And Cat
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Author : Valerie J. Wiebe
language : en
Publisher: John Wiley & Sons
Release Date : 2015-05-11

Drug Therapy For Infectious Diseases Of The Dog And Cat written by Valerie J. Wiebe and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-11 with Medical categories.


Drug Therapy for Infectious Diseases of the Dog and Cat provides fast access to all the information needed to effectively and responsibly treat infectious disease in dogs and cats, with easy searching by either drug or organism. Provides fast access to essential information on prescribing antibiotics, antifungals, antiparasitics, and antivirals Offers alphabetical searching by either drug or organism Focuses on clinically relevant information Covers information on each drug using a common format for ease of use Presents a reliable quick reference to the correct use of antibiotics in veterinary practice



Host Pathogen Interaction


Host Pathogen Interaction
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Author : Gottfried Unden
language : en
Publisher: John Wiley & Sons
Release Date : 2016-09-06

Host Pathogen Interaction written by Gottfried Unden and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-06 with Science categories.


In light of the rapidity increasing incidence rate of bacterial and fungal infections with multi-resistant pathogens, the metabolic changes associated with host-pathogen interactions offer one of the most promising starting points for developing novel antibiotics. . Part one of this comprehensive guide describes the metabolic adaptation of pathogenic microbes in humans, while part two points to routes for the development of novel antibiotics. This is volume six of the book series on drug discovery in infectious diseases by Paul Selzer.