Host Pathogen Interaction
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Host Pathogen Interactions
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Author : Steffen Rupp
language : en
Publisher: Humana Press
Release Date : 2008-11-01
Host Pathogen Interactions written by Steffen Rupp and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-01 with Science categories.
In recent decades, infectious diseases, once believed to be fairly contained, have become a vital, resurgent field of research. In Host-Pathogen Interactions: Methods and Protocols, top experts examine the relationship between the host and the pathogen, crucial in the outcome of an infection and the establishment of disease or asymptomatic, commensal colonization by organisms. The step-by-step laboratory methods and protocols of this volume study host-pathogen interaction, with a focus on fungal, bacterial and parasitic pathogens, at a molecular level in order to reveal the mechanisms of infection and to identify the vulnerabilities of the pathogen of interest. Written in the highly successful Methods in Molecular BiologyTM series format, the chapters feature brief subject introductions, lists of the necessary materials and reagents, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Host-Pathogen Interactions: Methods and Protocols serves as an easy entry point for all those investigating the factors responsible for the pathogenicity of microorganisms.
Host Pathogen Interaction
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Author : Gottfried Unden
language : en
Publisher: John Wiley & Sons
Release Date : 2016-09-06
Host Pathogen Interaction written by Gottfried Unden and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-06 with Science categories.
In light of the rapidity increasing incidence rate of bacterial and fungal infections with multi-resistant pathogens, the metabolic changes associated with host-pathogen interactions offer one of the most promising starting points for developing novel antibiotics. . Part one of this comprehensive guide describes the metabolic adaptation of pathogenic microbes in humans, while part two points to routes for the development of novel antibiotics. This is volume six of the book series on drug discovery in infectious diseases by Paul Selzer.
Host Pathogen Interactions In Plant Disease
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Author : J. E. Vanderplank
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Host Pathogen Interactions In Plant Disease written by J. E. Vanderplank and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
This book describes the genetics, biochemistry, and epidemiology of host-pathogen interactions in plant disease, especially as they concern the breeding of crops for disease resistance. It analyzes a wealth of information that has not previously been recorded in other books or reviews. Some of it stems from basic surveys of disease in the field. The analysis of these surveys not only explains a great deal about host-pathogen interactions that was heretofore obscure, but also indicates directions for future research. Other data, from original papers, have now been coordinated for the first time and organized in a way that suggests new areas of research. The book contains more than fifty new tables that integrate data and relate them to general principles of host-pathogen interactions. For plant pathologists and plant breeders concerned with the control of plant disease, the book shows how to manipulate the host and, indirectly, the pathogen in order to control disease. It analyzes records of resistance against disease that time has shown to be stable in an effort to determine what has kept this resistance stable. It also analyzes the structure of virulence in populations of a pathogen, and demonstrates how virulence can be deliberately restricted. The author updates information on the gene-for-gene hypothesis and discusses the numerical and biological implications of the hypothesis. He analyzes the structure of epidemics based on three fundamental variables: the initial inoculum, the progeny/parent ratio of the pathogen, and the latent period. The author concentrates on the progeny/parent ratio - a subject not hitherto probed in detail in the literature - and shows how to determine the type of epidemic that can occur.
Cell Signaling In Host Pathogen Interactions The Host Point Of View
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Author : Diana Bahia
language : en
Publisher: Frontiers Media SA
Release Date : 2018-03-23
Cell Signaling In Host Pathogen Interactions The Host Point Of View written by Diana Bahia and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-23 with categories.
The ability of pathogens, such as parasites, bacteria, fungi and viruses to invade, persist and adapt in both invertebrate and vertebrate hosts is multifactorial and depends on both pathogen and host fitness. Communication between a pathogen and its host relies on a wide and dynamic array of molecular interactions. Through this constant communication most pathogens evolved to be relatively benign, whereas killing of its host by a pathogen represents a failure to adapt. Pathogens are lethal to their host when their interaction has not been long enough for adaptation. Evolution has selected conserved immune receptors that recognize signature patterns of pathogens as non-self elements and initiate host innate responses aimed at eradicating infection. Conversely, pathogens evolved mechanisms to evade immune recognition and subvert cytokine secretion in order to survive, replicate and cause disease. The cell signaling machinery is a critical component of the immune system that relays information from the receptors to the nucleus where transcription of key immune genes is activated. Host cells have developed signal transduction systems to maintain homeostasis with pathogens. Most cellular processes and cell signaling pathways are tightly regulated by protein phosphorylation in which protein kinases are key protagonists. Pathogens have developed multiple mechanisms to subvert important signal transduction pathways such as the mitogen activated protein kinase (MAPK) and the nuclear factor kB (NF-kB) pathways. Pathogens also secrete effectors that manipulate actin cytoskeleton and its regulators, hijack cell cycle machinery and alter vesicular trafficking. This research topic focuses on the cellular signaling mechanisms that are essential for host immunity and their subversion by pathogens.
Molecular Aspects Of Host Pathogen Interactions
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Author : Society for General Microbiology. Symposium
language : en
Publisher: Cambridge University Press
Release Date : 1997-05-13
Molecular Aspects Of Host Pathogen Interactions written by Society for General Microbiology. Symposium and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-05-13 with Medical categories.
Reports the latest advances in defining the molecular basis of infection in both bacterial and viral systems.
Tuberculosis Host Pathogen Interactions
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Author : Jeffrey D. Cirillo
language : en
Publisher: Springer Nature
Release Date : 2019-09-10
Tuberculosis Host Pathogen Interactions written by Jeffrey D. Cirillo and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-10 with Medical categories.
This book summarizes the progress in studies of tuberculosis host-pathogen interactions from several perspectives: molecular microbiology, immunology, animal models, clinical studies, epidemiology, and drug discovery. Tuberculosis (TB) remains a severe global public health problem. Complex interactions between environmental, microbial and host factors lead to clinically relevant infections. Studies on bacterial virulence, host-genetic, and immunological factors contributing to the susceptibility to TB provide an ever-growing foundation of knowledge that is critical to finding new interventions. Studies of immune mechanisms against M. tuberculosis infection have identified immunological markers associated with specific phenotypes in the host, providing insight into how they may be used to augment current treatment strategies. Recent advances in diagnosis, therapeutics and vaccines, as well as basic-research oriented studies have shed light on the development of new directions for prevention, treatment and control of TB. Improved understanding of the interplay between the bacterium and host is a key component of reducing incidence worldwide.
Host Pathogen Interactions
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Author : Annette W. Barton
language : en
Publisher: Nova Biomedical Books
Release Date : 2010
Host Pathogen Interactions written by Annette W. Barton and has been published by Nova Biomedical Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Communicable diseases categories.
In this book, some of the strategies employed by M.
Host Pathogen Interaction In Central Nervous System Infection
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Author : Federico Iovino
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-04
Host Pathogen Interaction In Central Nervous System Infection written by Federico Iovino and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-04 with Science categories.
Severe Acute Respiratory Syndrome Coronavirus 2 Host Pathogen Interactions And Cellular Signaling Vol Ii
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Author : Vikas Sood
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-16
Severe Acute Respiratory Syndrome Coronavirus 2 Host Pathogen Interactions And Cellular Signaling Vol Ii written by Vikas Sood and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-16 with Science categories.
Severe Acute Respiratory Syndrome Coronavirus 2 Host Pathogen Interactions And Cellular Signaling
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Author : Vikas Sood
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-07
Severe Acute Respiratory Syndrome Coronavirus 2 Host Pathogen Interactions And Cellular Signaling written by Vikas Sood and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-07 with Science categories.