Model Organisms For Microbial Pathogenesis Biofilm Formation And Antimicrobial Drug Discovery
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Model Organisms For Microbial Pathogenesis Biofilm Formation And Antimicrobial Drug Discovery
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Author : Busi Siddhardha
language : en
Publisher: Springer Nature
Release Date : 2020-03-28
Model Organisms For Microbial Pathogenesis Biofilm Formation And Antimicrobial Drug Discovery written by Busi Siddhardha and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-28 with Science categories.
This book provides essential insights into microbial pathogenesis, host-pathogen interactions, and the anti-microbial drug resistance of various human pathogens on the basis of various model organisms. The initial sections of the book introduce readers to the mechanisms of microbial pathogenesis, host-pathogen interactions, anti-microbial drug resistance, and the dynamics of biofilm formation. Due to the emergence of various microbial resistant strains, it is especially important to understand the prognosis for microbial infections, disease progression profiles, and mechanisms of resistance to antibiotic therapy in order to develop novel therapeutic strategies. In turn, the second part of the book presents a comparative analysis of various animal models to help readers understand microbial pathogenesis, host-pathogen interactions, anti-microbial drug discovery, anti-biofilm therapeutics, and treatment regimes. Given its scope, the book represents a valuable asset for microbiologists, biotechnologists, medical professionals, drug development researchers, and pharmacologists alike.
Bacterial Biofilms
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Author : Tony Romeo
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-26
Bacterial Biofilms written by Tony Romeo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-26 with Medical categories.
Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.
Microbial Biofilms
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Author : Mahmoud Ghannoum
language : en
Publisher: John Wiley & Sons
Release Date : 2015-10-01
Microbial Biofilms written by Mahmoud Ghannoum and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-01 with Science categories.
An examination of the research and translational application to prevent and treat biofilm-associated diseases In the decade since the first edition of Microbial Biofilms was published, the interest in this field has expanded, spurring breakthrough research that has advanced the treatment of biofilm-associated diseases. This second edition takes the reader on an exciting, extensive review of bacterial and fungal biofilms, ranging from basic molecular interactions to innovative therapies, with particular emphasis on the division of labor in biofilms, new approaches to combat the threat of microbial biofilms, and how biofilms evade the host defense. Chapters written by established investigators cover recent findings, and contributions from investigators new to the field provide unique and fresh insights. Specifically, Microbial Biofilms provides state-of-the-art research in the field of bacterial and fungal biofilms detailed descriptions of the in vitro and in vivo models available to evaluate microbial biofilms future areas of research and their translational and clinical applications Microbial Biofilms is a useful reference for researchers and clinicians. It will also provide insight in the dynamic field of microbial biofilms for graduate and postgraduate students.
Current Trends In Microbial Biotechnology For Sustainable Agriculture
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Author : Ajar Nath Yadav
language : en
Publisher: Springer Nature
Release Date : 2020-11-10
Current Trends In Microbial Biotechnology For Sustainable Agriculture written by Ajar Nath Yadav and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-10 with Technology & Engineering categories.
Microbial biotechnology is an emerging field with applications in a broad range of sectors involving food security, human nutrition, plant protection and overall basic research in the agricultural sciences. The environment has been sustaining the burden of mankind from time immemorial, and our indiscriminate use of its resources has led to the degradation of the climate, loss of soil fertility, and the need for sustainable strategies. The major focus in the coming decades will be on achieving a green and clean environment by utilizing soil and plant-associated beneficial microbial communities. Plant-microbe interactions include the association of microbes with plant systems: epiphytic, endophytic and rhizospheric. The microbes associated with plant ecosystems play an important role in plant growth, development, and soil health. Moreover, soil and plant microbiomes help to promote plant growth, either directly or indirectly by means of plant growth-promoting mechanisms, e.g. the release of plant growth regulators; solubilization of phosphorus, potassium and zinc; biological nitrogen fixation; or by producing siderophores, ammonia, HCN and other secondary metabolites. These beneficial microbial communities represent a novel and promising solution for agro-environmental sustainability by providing biofertilizers, bioprotectants, and biostimulants, in addition to mitigating various types of abiotic stress in plants. This book focuses on plant-microbe interactions; the biodiversity of soil and plant microbiomes; and their role in plant growth and soil health. Accordingly, it will be immensely useful to readers working in the biological sciences, especially microbiologists, biochemists and microbial biotechnologists.
Eskape Pathogens
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Author : Siddhardha Busi
language : en
Publisher: Springer Nature
Release Date :
Eskape Pathogens written by Siddhardha Busi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Microbes In Microbial Communities
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Author : Raghvendra Pratap Singh
language : en
Publisher: Springer Nature
Release Date : 2022-01-01
Microbes In Microbial Communities written by Raghvendra Pratap Singh and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-01 with Science categories.
The book overviews the complex interactions amongst the microbes and their possible applications. Emphasis has been made to include a wide spectrum of experimental and theoretical contributions from eminent researchers in the field. Microbial communities are the assemblages of microorganisms of various species which live together in the same environment and continuously interact with each other. The microbial cells in communities display unique phenotypes that affect the survival and reproduction of other cells present around them. These phenotypes constitute the social adaptations that drive the interactions between microbial cells. The interactions, further determine the productivity, stability and the ability of community to resist the environmental perturbations. These microbial communities live with extremely competitive niche and fight for their survival and genetic persistence. But they frequently appear in niche with multifaceted and interactive webs rather than the planktonic nature. This can be within the same species or with different species, or even with diverse genera and families. It either a competitive winner community whereas the “weaker” strain goes extinct or a competitor that coexist with their metabolic secretory potentials or a separator that assigned their own community territorial niches. Sometimes, it can be neutral or tritagonist. These microbial associations within the microbiome provides the foundation for diverse forms of microbial ecology and determined the applied perspectives for agriculture, clinical and industrial sectors. This book will be useful to postgraduate students, researchers from academic as well as industry working in the field of microbial exploration with keen interest in survival factors and mechanism of their survival by various ecological and functional strategies.
Biofilm Infections
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Author : Thomas Bjarnsholt
language : en
Publisher: Springer
Release Date : 2014-10-11
Biofilm Infections written by Thomas Bjarnsholt and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-11 with Science categories.
This book will cover both the evidence for biofilms in many chronic bacterial infections as well as the problems facing these infections such as diagnostics and treatment regimes. A still increasing interest and emphasis on the sessile bacterial lifestyle biofilms has been seen since it was realized that that less than 0.1% of the total microbial biomass lives in the planktonic mode of growth. The term was coined in 1978 by Costerton et al. who defined the term biofilm for the first time.In 1993 the American Society for Microbiology (ASM) recognised that the biofilmmode of growth was relevant to microbiology. Lately many articles have been published on the clinical implications of bacterial biofilms. Both original articles and reviews concerning the biofilm problem are available.
Antimicrobial Photodynamic Therapy
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Author : Siddhardha Busi
language : en
Publisher: CRC Press
Release Date : 2023-08-22
Antimicrobial Photodynamic Therapy written by Siddhardha Busi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-22 with Medical categories.
Antimicrobial Photodynamic Therapy: Concepts and Applications explores the novel antimicrobial therapeutic technique. As the world searches for new, efficient modalities for fighting microorganisms, this book offers a complete understanding of the concept, and knowledge about the emerging technique ‘antimicrobial photodynamic therapy’ (aPDT) for the scientific communities and budding researchers. The book aligns concepts, significance, and applications of the technique systematically. Chapters in the book cover microorganisms, pathogenesis, conventional treatment methods, and significance of new treatment approaches to the concept of antimicrobial photodynamic therapy. The authors describe the mechanism behind it, with applications and examples from research studies. The book discusses photosensitisers in detail, with one chapter emphasising natural photosensitisers. Use of nanostructures in the antimicrobial photodynamic therapy is elaborated on, and we conclude with a well-explored application of the therapeutic technique in dentistry. Features: Efficiently covers the topic in detail with scientifically proven examples. Applications of the therapeutic approach are well discussed, and readers can learn about the research gaps, challenges, and future of the technique. Starts from basics, enabling readers to understand why the approach is relevant and important for study. Simplistic elucidated concepts and applications make it accessible at all levels.
Adaptation Of Halophilic Halotolerant Microorganisms And Their Applications
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Author : Furkan Orhan
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-25
Adaptation Of Halophilic Halotolerant Microorganisms And Their Applications written by Furkan Orhan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-25 with Science categories.
101 Primary Care Case Studies
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Author : Sampath Wijesinghe, DHSc, MS, MPAS, PA-C, AAHIVS
language : en
Publisher: Springer Publishing Company
Release Date : 2020-12-15
101 Primary Care Case Studies written by Sampath Wijesinghe, DHSc, MS, MPAS, PA-C, AAHIVS and has been published by Springer Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-15 with Medical categories.
Real-life primary care case studies* from more than 50 primary care providers, including physician assistants, nurse practitioners, and physicians! 101 Primary Care Case Studies offers real-life patient scenarios and critical thinking exercises to help you work through a patient’s chief complaint. Through narrative case studies, you will determine how best to diagnose, treat, and manage your patient based on the history of present illness, review of systems, relevant history, and physical examination findings. This workbook will ask probing questions to help you determine differential and most likely diagnoses, diagnostic tests to order, and appropriate patient management strategies using relevant and timely references to support your decisions. The organization of each case study simulates the patient care journey from chief complaint to outcome. Serving as a virtual clinical preceptor, this workbook can be used independently or in a classroom setting. It is accompanied by a robust online student supplement that provides answers to all questions, real outcomes of the cases, and valuable personal insights from the authors on how the patient was successfully managed. Not only will this workbook help you work through patient cases clinically, it will also share important, but often overlooked, bedside manner skills needed to successfully communicate with and care for your patients. Covering conditions across all organ systems and across the lifespan, this workbook is organized by chief complaint, providing an authentic perspective on what to expect in the patient care environment. It even includes information on pathophysiology and how to use ICD-10 and CPT (E/M) codes in your documentation. The book uniquely weaves together both the science and art of medicine by including personal insights into quality and compassionate care. Key Features Provides real-life patient cases from an interprofessional author team of physician assistants, nurse practitioners, and physicians Uses a templated case study design and critical thinking exercises to help you methodically work through various patient scenarios Teaches clinical and bedside manner skills imperative for delivering quality patient care Covers patients across the lifespan, including pediatric, adolescent, adult, and geriatric populations Offers additional insight on patient education, medical and legal concerns, and interprofessional collaboration Includes a robust online student supplement with valuable insights from the authors on how they successfully managed the cases Provides instructors with a table of contents that is filterable by chief complaint, diagnosis, patient population, and organ system *Details changed to protect patient information.