Drug Use During Pregnancy With Focus On Antidepressants
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Drug Use During Pregnancy With Focus On Antidepressants
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Author : Emelie Wolgast
language : en
Publisher: Linköping University Electronic Press
Release Date : 2020-11-20
Drug Use During Pregnancy With Focus On Antidepressants written by Emelie Wolgast and has been published by Linköping University Electronic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-20 with Electronic books categories.
Background: More than half of pregnant women use at least one prescribed medication during pregnancy, and almost all pregnant women use some kind of over-the-counter medication. Depression is one of the most common diseases in the world today, also during the peripartum period. The prevalence of pregnant women using antidepressant medication is increasing. General knowledge about the use of medication during pregnancy needs to improve. The overall aim of the studies on which this thesis is based is therefore to examine different aspects of medication use during pregnancy, with a focus on antidepressants. Material and methods: Study I was a questionnaire study where 850 pregnant women were asked about their perceptions on medication use during pregnancy. In Study II, plasma samples from 200 women were obtained at gestational weeks 10-12 and 25, and screened for drugs. The results of the analysis were compared with medication use noted in antenatal medical care records. Study III was a national register‐based cohort study including 262,329 pregnant women, and their first child born in 2012-2015. Maternal obstetric and neonatal outcomes were studied in three groups: women diagnosed with depression and who had redeemed an antidepressant before becoming pregnant and women who were diagnosed with depression and who had redeemed an antidepressant both before and during pregnancy, were compared with each other and with women who had neither been diagnosed with depression nor been prescribed antidepressants. Study IV was a pharmacokinetic study that included 81 pregnant women with ongoing antidepressant medical treatment. Antidepressant drug and metabolite concentrations were measured throughout pregnancy. Participants were genotyped for enzymes involved in antidepressant drug metabolism, i.e. CYP2D6 and CYP2C19. Results and conclusions: The majority of pregnant women in our study considered the use of medication during pregnancy as either “probably harmful” or “harmful”, and this perception was associated with non-use of medication. The women had high confidence in health care professionals when seeking advice about medication. There was a good coherence between reported drug intake in antenatal care records and presence of the drug in the pregnant women’s blood. For drugs prescribed for continuous use the coherence was 100%; thus, the reported use of medication in antenatal records is reliable. Women with major depressive disorder and antidepressant medication prior to becoming pregnant were at increased risk for adverse obstetric and neonatal outcomes compared with women without major depressive disorder. Continuation of antidepressant medication during pregnancy somewhat increased the risk of adverse obstetric and neonatal outcomes. The dose-adjusted concentrations of sertraline and citalopram and their metabolites, did not change significantly throughout pregnancy. Observed concentrations of escitalopram, mirtazapine and venlafaxine did not appear to change.
Opioid Use Disorders In Pregnancy
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Author : Tricia E. Wright
language : en
Publisher:
Release Date : 2018-05-10
Opioid Use Disorders In Pregnancy written by Tricia E. Wright and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-10 with Medical categories.
Gain guidance and support when treating the high-risk population of women confronting (or battling) opioid-use disorders during pregnancy.
Clinical Pharmacology During Pregnancy
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Author : Donald Mattison
language : en
Publisher: Academic Press
Release Date : 2012-12-05
Clinical Pharmacology During Pregnancy written by Donald Mattison and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-05 with Medical categories.
Clinical Pharmacology During Pregnancy is written for clinicians, physicians, midwives, nurses, pharmacists and other medical professionals directly involved in the care of women during pregnancy. This book focuses on the impact of pregnancy on drug disposition and also includes coverage of treatments for diseases of specific body systems, as well as essential content on dosing and efficacy. Written in a clear and practical manner, this reference provides easily accessible information and clinical guidance on how best to treat women with medications during pregnancy.
5 Ht2b Receptors
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Author : Luc Maroteaux
language : en
Publisher: Springer Nature
Release Date : 2021-03-12
5 Ht2b Receptors written by Luc Maroteaux and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-12 with Medical categories.
This contributed volume provides a comprehensive assessment of the roles played by 5-HT2B receptors in humans. These receptors have been shown to play an important role is the cardiac, intestinal, and central nervous systems as well as in bone marrow formation and growth. In this book, expert researchers present their findings on molecular and physiological/pathological aspects of 5-HT2B receptors. The molecular section includes a discussion of the genetics of 5-HT2B receptors and impulse control. The physiological section covers their role in many biological systems including the nervous system, the heart, and the lungs.
Women S Mental Health
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Author : Susan G. Kornstein
language : en
Publisher: Guilford Press
Release Date : 2004-12-15
Women S Mental Health written by Susan G. Kornstein and has been published by Guilford Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-12-15 with Psychology categories.
This comprehensive reference and text synthesizes a vast body of clinically useful knowledge about women's mental health and health care. Coverage includes women's psychobiology across the life span--sex differences in neurobiology and psychopharmacology and psychiatric aspects of the reproductive cycle--as well as gender-related issues in assessment and treatment of frequently encountered psychiatric disorders. Current findings are presented on sex differences in epidemiology, risk factors, presenting symptoms, treatment options and outcomes, and more. Also addressed are mental health consultation to other medical specialties, developmental and sociocultural considerations in service delivery, and research methodology and health policy concerns.
Pharmacoepidemiology
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Author : Brian L. Strom
language : en
Publisher: John Wiley & Sons
Release Date : 2019-12-16
Pharmacoepidemiology written by Brian L. Strom and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-16 with Medical categories.
This classic, field-defining textbook, now in its sixth edition, provides the most comprehensive guidance available for anyone needing up-to-date information in pharmacoepidemiology. This edition has been fully revised and updated throughout and continues to provide a rounded view on all perspectives from academia, industry and regulatory bodies, addressing data sources, applications and methodologies with great clarity.
The Wiley Handbook Of Disruptive And Impulse Control Disorders
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Author : John E. Lochman
language : en
Publisher: John Wiley & Sons
Release Date : 2017-08-21
The Wiley Handbook Of Disruptive And Impulse Control Disorders written by John E. Lochman and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-21 with Psychology categories.
The definitive reference to the policies and practices for treating disruptive and impulse-control disorders, edited by renowned experts The Wiley Handbook of Disruptive and Impulse-Control Disorders offers a comprehensive overview that integrates the most recent and important scholarship and research on disruptive and impulse-control disorders in children and adolescents. Each of the chapters includes a summary of the most relevant research and knowledge on the topic and identifies the implications of the findings along with important next directions for research. Designed to be practical in application, the text explores the applied real-world value of the accumulated research findings, and the authors include policy implications and recommendations. The Handbook address the nature and definition of the disorders, the risk factors associated with the development and maintenance of this cluster of disorders, assessment processes, as well as the evidence-based treatment and prevention practices. The volume incorporates information from the ICD-11, a newly revised classification system, along with the recently published DSM-5. This important resource: Contains a definitive survey that integrates the most recent and important research and scholarship on disruptive and impulse-control disorders in children and adolescents Emphasizes the applied real-world value of the accumulated research findings Explores the policy implications and recommendations to encourage evidence-based practice Examines the nature and definition, risk factors, assessment, and evidence-based practice; risk factors are subdivided into child, family, peer group and broader context Considers changes, advances and controversies associated with new and revised diagnostic categories Written for clinicians and professionals in the field, The Wiley Handbook of Disruptive and Impulse-Control Disorders offers an up-to-date review of the most authoritative scholarship and research on disruptive and impulse-control disorders in children and adolescents as well as offering recommendations for practice.
Drug Utilization Research
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Author : Monique Elseviers
language : en
Publisher: John Wiley & Sons
Release Date : 2016-05-31
Drug Utilization Research written by Monique Elseviers and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-31 with Medical categories.
Drug Utilization Research (DUR) is an eclectic scientific discipline, integrating descriptive and analytical methods for the quantification, understanding and evaluation of the processes of prescribing, dispensing and consumption of medicines and for the testing of interventions to enhance the quality of these processes. The discipline is closely related and linked mainly to the broader field of pharmacoepidemiology, but also to health outcomes research, pharmacovigilance and health economics. Drug Utilization Research is a unique, practical guide to the assessment and evaluation of prescribing practices and to interventions to improve the use of medicines in populations. Edited by an international expert team from the International Society for Pharmacoepidemiology (ISPE), DUR is the only title to cover both the methodology and applications of drug utilization research and covers areas such as health policy, specific populations, therapeutics and adherence.
Perinatal Psychopharmacology
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Author : Faruk Uguz
language : en
Publisher: Springer
Release Date : 2019-01-24
Perinatal Psychopharmacology written by Faruk Uguz and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-24 with Medical categories.
This book focuses on recent advances in research and practical recommendations regarding the use of psychotropic drugs during pregnancy and lactation, two important social and psychological life events for women. In addition to the social context, including the addition of a new family member, many women experience the occurrence or recurrence of psychiatric disorders during the perinatal period. Psychiatric disorders during this period can have negative effects on the fetus, infant and other children in the family, and can result in functional impairment among mothers. The book offers a comprehensive overview of psychopharmacological treatments for nearly all specific psychiatric conditions (e.g. bipolar disorder, panic disorder, obsessive-compulsive disorder) and includes chapters on clinical approaches to treating these disorders. As such, it will appeal to a wide readership, including psychiatrists, obstetricians, gynecologists and pediatricians.
Volpe S Neurology Of The Newborn E Book
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Author : Joseph J. Volpe
language : en
Publisher: Elsevier Health Sciences
Release Date : 2017-09-13
Volpe S Neurology Of The Newborn E Book written by Joseph J. Volpe and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-13 with Medical categories.
A clear, engaging writing style, hundreds of full-color images, and new information throughout make Volpe’s Neurology of the Newborn, 6th Edition, an indispensable resource for those who provide care for neonates with neurological conditions. World authority Dr. Joseph Volpe, along with Dr. Terrie E. Inder and other distinguished editors, continue the unparalleled clarity and guidance you’ve come to expect from the leading reference in the field – keeping you up to date with today’s latest advances in diagnosis and management, as well as the many scientific and technological advances that are revolutionizing neonatal neurology. Features a brand new, full-color design with hundreds of new figures, tables, algorithms, and micrographs. Includes two entirely new chapters: Neurodevelopmental Follow-Up and Stroke in the Newborn; a new section on Neonatal Seizures; and an extensively expanded section on Hypoxic-Ischemia and Other Disorders. Showcases the experience and knowledge of a new editorial team, led by Dr. Joseph Volpe and Dr. Terrie E. Inder, Chair of the Department of Pediatric Newborn Medicine at Brigham and Women’s Hospital, all of whom bring a wealth of insight to this classic text. Offers comprehensive updates from cover to cover to reflect all of the latest information regarding the development of the neural tube; prosencephalic development; congenital hydrocephalus; cerebellar hemorrhage; neuromuscular disorders and genetic testing; and much more. Uses an improved organization to enhance navigation.