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Dynamical Biostatistical Models


Dynamical Biostatistical Models
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Dynamical Biostatistical Models


Dynamical Biostatistical Models
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Author : Daniel Commenges
language : en
Publisher: CRC Press
Release Date : 2015-10-02

Dynamical Biostatistical Models written by Daniel Commenges and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-02 with Mathematics categories.


Dynamical Biostatistical Models presents statistical models and methods for the analysis of longitudinal data. The book focuses on models for analyzing repeated measures of quantitative and qualitative variables and events history, including survival and multistate models. Most of the advanced methods, such as multistate and joint models, can be ap



Essentials Of A Successful Biostatistical Collaboration


Essentials Of A Successful Biostatistical Collaboration
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Author : Arul Earnest
language : en
Publisher: CRC Press
Release Date : 2016-10-14

Essentials Of A Successful Biostatistical Collaboration written by Arul Earnest and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-14 with Mathematics categories.


The aim of this book is to equip biostatisticians and other quantitative scientists with the necessary skills, knowledge, and habits to collaborate effectively with clinicians in the healthcare field. The book provides valuable insight on where to look for information and material on sample size and statistical techniques commonly used in clinical research, and on how best to communicate with clinicians. It also covers the best practices to adopt in terms of project, time, and data management; relationship with collaborators; etc.



Multistate Models For The Analysis Of Life History Data


Multistate Models For The Analysis Of Life History Data
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Author : Richard J Cook
language : en
Publisher: CRC Press
Release Date : 2018-05-15

Multistate Models For The Analysis Of Life History Data written by Richard J Cook and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-15 with Mathematics categories.


Multistate Models for the Analysis of Life History Data provides the first comprehensive treatment of multistate modeling and analysis, including parametric, nonparametric and semiparametric methods applicable to many types of life history data. Special models such as illness-death, competing risks and progressive processes are considered, as well as more complex models. The book provides both theoretical development and illustrations of analysis based on data from randomized trials and observational cohort studies in health research. It features: Discusses a wide range of applications of multistate models, Presents methods for both continuously and intermittently observed life history processes, Gives a thorough discussion of conditionally independent censoring and observation processes, Discusses models with random effects and joint models for two or more multistate processes, Discusses and illustrates software for multistate analysis that is available in R, Target audience includes those engaged in research and applications involving multistate models.



Medical Biostatistics


Medical Biostatistics
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Author : Abhaya Indrayan
language : en
Publisher: CRC Press
Release Date : 2017-11-27

Medical Biostatistics written by Abhaya Indrayan and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-27 with Mathematics categories.


Encyclopedic in breadth, yet practical and concise, Medical Biostatistics, Fourth Edition focuses on the statistical aspects ofmedicine with a medical perspective, showing the utility of biostatistics as a tool to manage many medical uncertainties. This edition includes more topics in order to fill gaps in the previous edition. Various topics have been enlarged and modified as per the new understanding of the subject.



Statistical Methods For Healthcare Performance Monitoring


Statistical Methods For Healthcare Performance Monitoring
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Author : Alex Bottle
language : en
Publisher: CRC Press
Release Date : 2016-08-05

Statistical Methods For Healthcare Performance Monitoring written by Alex Bottle and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-05 with Mathematics categories.


Healthcare is important to everyone, yet large variations in its quality have been well documented both between and within many countries. With demand and expenditure rising, it’s more crucial than ever to know how well the healthcare system and all its components – from staff member to regional network – are performing. This requires data, which inevitably differ in form and quality. It also requires statistical methods, the output of which needs to be presented so that it can be understood by whoever needs it to make decisions. Statistical Methods for Healthcare Performance Monitoring covers measuring quality, types of data, risk adjustment, defining good and bad performance, statistical monitoring, presenting the results to different audiences and evaluating the monitoring system itself. Using examples from around the world, it brings all the issues and perspectives together in a largely non-technical way for clinicians, managers and methodologists. Statistical Methods for Healthcare Performance Monitoring is aimed at statisticians and researchers who need to know how to measure and compare performance, health service regulators, health service managers with responsibilities for monitoring performance, and quality improvement scientists, including those involved in clinical audits.



Emerging Non Clinical Biostatistics In Biopharmaceutical Development And Manufacturing


Emerging Non Clinical Biostatistics In Biopharmaceutical Development And Manufacturing
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Author : Harry Yang
language : en
Publisher: CRC Press
Release Date : 2016-11-30

Emerging Non Clinical Biostatistics In Biopharmaceutical Development And Manufacturing written by Harry Yang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-30 with Mathematics categories.


The premise of Quality by Design (QbD) is that the quality of the pharmaceutical product should be based upon a thorough understanding of both the product and the manufacturing process. This state-of-the-art book provides a single source of information on emerging statistical approaches to QbD and risk-based pharmaceutical development. A comprehensive resource, it combines in-depth explanations of advanced statistical methods with real-life case studies that illustrate practical applications of these methods in QbD implementation.



Repeated Measures Design With Generalized Linear Mixed Models For Randomized Controlled Trials


Repeated Measures Design With Generalized Linear Mixed Models For Randomized Controlled Trials
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Author : Toshiro Tango
language : en
Publisher: CRC Press
Release Date : 2017-09-14

Repeated Measures Design With Generalized Linear Mixed Models For Randomized Controlled Trials written by Toshiro Tango and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-14 with Mathematics categories.


Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials is the first book focused on the application of generalized linear mixed models and its related models in the statistical design and analysis of repeated measures from randomized controlled trials. The author introduces a new repeated measures design called S:T design combined with mixed models as a practical and useful framework of parallel group RCT design because of easy handling of missing data and sample size reduction. The book emphasizes practical, rather than theoretical, aspects of statistical analyses and the interpretation of results. It includes chapters in which the author describes some old-fashioned analysis designs that have been in the literature and compares the results with those obtained from the corresponding mixed models. The book will be of interest to biostatisticians, researchers, and graduate students in the medical and health sciences who are involved in clinical trials. Author Website:Data sets and programs used in the book are available at http://www.medstat.jp/downloadrepeatedcrc.html



Statistical Topics In Health Economics And Outcomes Research


Statistical Topics In Health Economics And Outcomes Research
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Author : Demissie Alemayehu
language : en
Publisher: CRC Press
Release Date : 2017-11-22

Statistical Topics In Health Economics And Outcomes Research written by Demissie Alemayehu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-22 with Mathematics categories.


With ever-rising healthcare costs, evidence generation through Health Economics and Outcomes Research (HEOR) plays an increasingly important role in decision-making about the allocation of resources. Accordingly, it is now customary for health technology assessment and reimbursement agencies to request for HEOR evidence, in addition to data from clinical trials, to inform decisions about patient access to new treatment options. While there is a great deal of literature on HEOR, there is a need for a volume that presents a coherent and unified review of the major issues that arise in application, especially from a statistical perspective. Statistical Topics in Health Economics and Outcomes Research fulfils that need by presenting an overview of the key analytical issues and best practice. Special attention is paid to key assumptions and other salient features of statistical methods customarily used in the area, and appropriate and relatively comprehensive references are made to emerging trends. The content of the book is purposefully designed to be accessible to readers with basic quantitative backgrounds, while providing an in-depth coverage of relatively complex statistical issues. The book will make a very useful reference for researchers in the pharmaceutical industry, academia, and research institutions involved with HEOR studies. The targeted readers may include statisticians, data scientists, epidemiologists, outcomes researchers, health economists, and healthcare policy and decision-makers.



Statistical Testing Strategies In The Health Sciences


Statistical Testing Strategies In The Health Sciences
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Author : Albert Vexler
language : en
Publisher: CRC Press
Release Date : 2017-12-19

Statistical Testing Strategies In The Health Sciences written by Albert Vexler and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-19 with Mathematics categories.


Statistical Testing Strategies in the Health Sciences provides a compendium of statistical approaches for decision making, ranging from graphical methods and classical procedures through computationally intensive bootstrap strategies to advanced empirical likelihood techniques. It bridges the gap between theoretical statistical methods and practical procedures applied to the planning and analysis of health-related experiments. The book is organized primarily based on the type of questions to be answered by inference procedures or according to the general type of mathematical derivation. It establishes the theoretical framework for each method, with a substantial amount of chapter notes included for additional reference. It then focuses on the practical application for each concept, providing real-world examples that can be easily implemented using corresponding statistical software code in R and SAS. The book also explains the basic elements and methods for constructing correct and powerful statistical decision-making processes to be adapted for complex statistical applications. With techniques spanning robust statistical methods to more computationally intensive approaches, this book shows how to apply correct and efficient testing mechanisms to various problems encountered in medical and epidemiological studies, including clinical trials. Theoretical statisticians, medical researchers, and other practitioners in epidemiology and clinical research will appreciate the book’s novel theoretical and applied results. The book is also suitable for graduate students in biostatistics, epidemiology, health-related sciences, and areas pertaining to formal decision-making mechanisms.



Computational Intelligence Methods For Bioinformatics And Biostatistics


Computational Intelligence Methods For Bioinformatics And Biostatistics
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Author : Maria Raposo
language : en
Publisher: Springer Nature
Release Date : 2020-01-22

Computational Intelligence Methods For Bioinformatics And Biostatistics written by Maria Raposo and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-22 with Computers categories.


This book constitutes the thoroughly refereed post-conference proceedings of the 15th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics., CIBB 2018, held in Caparica, Portugal, in September 2018. The 32 revised full papers were carefully reviewed and selected from 51 submissions. The papers present current trends at the edge of computer and life sciences, the application of computational intelligence to a system and synthetic biology and the consequent impact on innovative medicine were presented. Theoretical and experimental biologists also presented novel challenges and fostered multidisciplinary collaboration aiming to blend theory and practice, where the founding theories of the techniques used for modelling and analyzing biological systems are investigated and used for practical applications and the supporting technologies.