Effects Of Membrane Lipids On Protein Function
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Effects Of Membrane Lipids On Protein Function
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Author : Rutilio A. Fratti
language : en
Publisher: Frontiers Media SA
Release Date : 2021-06-30
Effects Of Membrane Lipids On Protein Function written by Rutilio A. Fratti and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-30 with Science categories.
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
Cholesterol Modulation Of Protein Function
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Author : Avia Rosenhouse-Dantsker
language : en
Publisher: Springer
Release Date : 2019-01-16
Cholesterol Modulation Of Protein Function written by Avia Rosenhouse-Dantsker and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-16 with Science categories.
In this book, renowned scientists describe the role of steroid chirality and modification of lipid membrane physical properties in the modulation of G protein-coupled receptors and ion channels. The application of commonly-used technical approaches such as mass spectrometry and nucleic magnetic resonance transfer spectroscopy for studies on cholesterol distribution and alteration of lipid bilayer characteristics is also discussed. This book offers comprehensive insights into the current understanding of cholesterol-driven modulation of protein function via mechanisms that extend beyond lipid-protein direct interactions. In the first part, the chapters introduce the reader to the use of the chemical derivatives of cholesterol as a valuable laboratory tool in the studies of cholesterol-driven modulation of protein function. In the second part, examples of cholesterol-induced changes in membrane physical characteristics are presented and discussed in light of their multifaceted contribution to the effect of cholesterol on protein function. The book will be of interest to undergraduate and graduate students as well as basic science and medical researchers with a keen interest in the biophysical properties of cholesterol and physiological consequences of cholesterol presence in biological systems.
Protein Lipid Interactions
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Author : C.Reyes Mateo
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-09-30
Protein Lipid Interactions written by C.Reyes Mateo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-30 with Science categories.
Biological membranes have long been identified as key elements in a wide variety of cellular processes including cell defense communication, photosynthesis, signal transduction, and motility; thus they emerge as primary targets in both basic and applied research. This book brings together in a single volume the most recent views of experts in the area of protein–lipid interactions, providing an overview of the advances that have been achieved in the field in recent years, from very basic aspects to specialized technological applications. Topics include the application of X-ray and neutron diffraction, infrared and fluorescence spectroscopy, and high-resolution NMR to the understanding of the specific interactions between lipids and proteins within biological membranes, their structural relationships, and the implications for the biological functions that they mediate. Also covered in this volume are the insertion of proteins and peptides into the membrane and the concomitant formation of definite lipid domains within the membrane.
General Principles
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Author : Ronald Aloia
language : en
Publisher: Elsevier
Release Date : 2012-12-02
General Principles written by Ronald Aloia and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Membrane Fluidity in Biology, Volume 2: General Principles provides an introduction to the fundamental concepts of membrane fluidity. Key topics discussed include lateral phase separations and phase transitions; hydrophobic and electrostatic effects of membrane lipid-protein interactions; isothermal phase transitions and the effects of ionic factors; and the influence of such components as cholesterol, phospholipids, fatty acids, and cellular water on the parameters of membrane fluidity. Each of these topics is elaborated in detail to provide a unique insight into the factors influencing the thermal molecular motions of membrane components, and hence cellular membrane function. Because such activities as membrane transport, enzyme kinetics, and receptor function are modulated by the physical state of the membrane lipids and proteins, a thorough comprehension of the molecular aspects of membrane fluidity is necessary to evaluate the arcane aspects of membrane-related cellular activities. This book will be useful to scientists and researchers concerned with the molecular principles of cellular and organelle function. It also provides an appropriate background for Volume 3, Cellular Aspects and Disease Processes, and for subsequent discussion of the relationship of membrane fluidity to environmental parameters, drugs, anesthetics, and other exogenous agents.
The Regulation Of Membrane Lipid Metabolism Second Edition
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Author : Guy A. Thompson, Jr.
language : en
Publisher: CRC Press
Release Date : 1992-03-10
The Regulation Of Membrane Lipid Metabolism Second Edition written by Guy A. Thompson, Jr. and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-03-10 with Medical categories.
This book provides a concise description of the metabolic pathways by which lipids of animal and plant membranes are formed. The book emphasizes modulation of these pathways by hormones, diet, environmental stress, and other factors. This new edition is extensively revised, containing new material on topics such as lipid-mediated signal transduction and lipid-induced protein translocation. The new edition also features an entirely new chapter on lipids covalently bound to proteins. The book is excellent for all researchers and students interested in membrane lipid metabolism.
Direct Mechanisms In Cholesterol Modulation Of Protein Function
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Author : Avia Rosenhouse-Dantsker
language : en
Publisher: Springer
Release Date : 2019-05-16
Direct Mechanisms In Cholesterol Modulation Of Protein Function written by Avia Rosenhouse-Dantsker and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-16 with Science categories.
In this book, renowned scientists describe how cholesterol interacts with various proteins. Recent progress made in the high-resolution visualization of cholesterol-protein interactions using crystallography and cryogenic electron microscopy has substantially advanced the knowledge of critical features. These features enable specific recognition of the cholesterol molecule by proteins, a process that was built on earlier studies using binding assays, computational modeling and site-directed mutagenesis. Direct Mechanisms in Cholesterol Modulation of Protein Function offers comprehensive insights into the current understanding of cholesterol-driven modulation of protein function via direct sensing. Its nine chapters are organized into two distinct parts. In the first part, the chapters introduce the reader to the general characteristics of cholesterol binding sites in proteins. This part starts with a tour into common cholesterol recognition motifs, followed by an overview of the major classes of steroid-binding proteins. It then continues with two chapters that present a comprehensive analysis of molecular and structural characteristics of cholesterol binding sites in transmembrane and soluble protein domains. In the second part of the book, examples of cholesterol binding sites and consequences of specific cholesterol recognition for protein function are presented for G protein-coupled receptors, ion channels and cholesterol-transporting proteins. The book is valuable for undergraduate and graduate students in biochemistry and nutrition, as well as basic science and medical researchers with a keen interest in the biophysical properties of cholesterol and physiological consequences of cholesterol presence in biological systems.
Protein Lipid And Membrane Traffic
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Author : North Atlantic Treaty Organization. Scientific Affairs Division
language : en
Publisher: IOS Press
Release Date : 2000
Protein Lipid And Membrane Traffic written by North Atlantic Treaty Organization. Scientific Affairs Division and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Biological transport categories.
This text concentrates on the following specific topics: the dynamic character of lipids and proteins in biological membranes; the existence of specific domains in membranes including their visualisation; the molecular mechanisms of intracellular transport of membrane constituents and the involvement of lipid-protein interactions in these processes; protein assembly; structure and folding and transport through membranes; and the intracellular sorting and targeting of individual membrane components as well as different organelles."
New Developments In Lipid Protein Interactions And Receptor Function
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Author : K.W.A. Wirtz
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
New Developments In Lipid Protein Interactions And Receptor Function written by K.W.A. Wirtz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
A NATO Advanced Study Institute on "New Developments in Lipid-Protein Interactions and Receptor Function" was held on the Island of Spetsai, Greece, from August 16-27, 1992. This Institute was organized to bring together researchers in the field of membrane organization and dynamics with those actively involved in studies on receptor function, signal transduction mechanisms and gene regulation. 2 Presentations and discussions focussed on the regulation of intracellular Ca +-levels, on the second messengers derived from inositol lipids and on the specific phospholipase C isozymes involved in these processes. A major focus was on G-proteins and the effect of lipid anchors on their function. These principles of regulation were further discussed in the context of receptors for acetylcholine, lysophosphatidic acid and low-density lipoproteins. In addition, various aspects of the genomic regulation of cell growth and differentiation by transcription factors were presented. These topics were put into perspective by discussing the most recent developments in lipid-protein interactions, protein insertion into membranes, membrane lipid organization and lipid dynamics as mediated by phospholipid transfer proteins. This book presents the content of the major lectures and a selection of the most relevant of the most important topics posters. These proceedings offer a comprehensive account presented during the course of the Institute. The book is intended to make these proceedings accessible to a large audience.
Lipid Domains And The Relationship To Membrane Function
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Author : Roland C. Aloia
language : en
Publisher:
Release Date : 1988
Lipid Domains And The Relationship To Membrane Function written by Roland C. Aloia and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Lipids categories.