Egcg And Voluntary Exercise
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Egcg And Voluntary Exercise
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Author : Jennifer M. Walker
language : en
Publisher:
Release Date : 2013
Egcg And Voluntary Exercise written by Jennifer M. Walker and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Alzheimer's disease categories.
Previous work with the TgCRND8 mouse model of Alzheimer's disease has shown that voluntary exercise implemented for long time periods (5-months) and starting at very young ages (1-month), prior to the development of disease pathology, reduces cognitive impairments; however, approximately 1-month of exercise started at 80-days failed to provide cognitive improvements for male mice. Additionally, research has shown that EGCG, a botanical polyphenol, can reduce amyloid-beta levels, mitigate oxidative stress and reduce some of the cognitive impairments associated with Alzheimer's disease in the Tg2576 murine model; however, oral administration of EGCG had not been yet evaluated in the TgCRND8 strain. The present study investigated the effects of 4-months of exercise treatment, implemented at the beginning of pathology development (2-months of age), in conjunction with the effects of EGCG treatment on: 1) behavioral measures: learning and memory performance in the Barnes maze, nest building, the open-field, anxiety in the light-dark box, and 2) soluble, amyloid-beta levels in the cortex and hippocampus. Untreated Tg mice showed deficits in nest building behaviors, as well as poor spatial learning in the Barnes maze. Four-months of EGCG and exercise treatment reversed nest building and spatial learning deficits, and lowered soluble, Ab1-42 levels in the cortex of Tg animals. This research was supported by NIH grant funding (2P01 AG18357).
Molecular And Cellular Regulation Of Adaptation To Exercise
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Author : Claude Bouchard
language : en
Publisher: Academic Press
Release Date : 2015-11-16
Molecular And Cellular Regulation Of Adaptation To Exercise written by Claude Bouchard and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-16 with Science categories.
Molecular Aspects of Exercise Biology and Exercise Genomics, the latest volume in the Progress in Molecular Biology and Translational Science series includes a comprehensive summary of the evidence accumulated thus far on the molecular and cellular regulation of the various adaptations taking place in response to exercise. Changes in the cellular machinery are described for multiple tissues and organs in terms of signaling pathways, gene expression, and protein abundance. Adaptations to acute exercise as well as exposure to regular exercise are also discussed and considered. Includes a comprehensive summary of the evidence accumulated thus far on the molecular and cellular regulation of the various adaptations taking place in response to exercise Contains contributions from leading authorities Informs and updates on all the latest developments in the field of exercise biology and exercise genomics
Phytomedicine And Alzheimer S Disease
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Author : Atanu Bhattacharjee
language : en
Publisher: CRC Press
Release Date : 2020-10-25
Phytomedicine And Alzheimer S Disease written by Atanu Bhattacharjee and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-25 with Health & Fitness categories.
Alzheimer's disease, one of the most rapidly growing neurodegenerative disorders, is characterized by a progressive loss of memory. Despite several advances in the field of medical therapeutics, a viable treatment for Alzheimer's disease would be of great importance. Medicinal plants represent a largely untapped reservoir of natural medicines and potential sources of anti-Alzheimer’s drugs. The structural diversity of their phytoconstituents makes these plants a valuable source of novel lead compounds in the quest for drugs to treat Alzheimer's disease. Based on traditional literature and up-to-date research, various new therapeutically active compounds have been identified from phytoextracts, which could be useful in the treatment of cognitive disorders. Phytomedicine and Alzheimer’s Disease presents information on Mechanistic aspects of neurodegeneration in Alzheimer’s disease and the role of phytochemicals as restorative agents Understanding the complex biochemical aspects of Alzheimer’s disease Pre-clinical approaches to evaluating drugs to target Alzheimer’s disease Assessing alternative approaches to treating Alzheimer’s disease and the role of alternative medicine to delay the symptomatic progression of this disease Epigenetic changes in Alzheimer’s disease and possible therapeutic or dietary interventions This book serves as an excellent resource for scientific investigators, academics, biochemists, botanists, and alternative medicine practitioners who work to advance the role of phytomedicines in treating Alzheimer’s disease.
Medicinal Plants Recent Advances In Research And Development
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Author : Hsin-Sheng Tsay
language : en
Publisher: Springer
Release Date : 2016-10-25
Medicinal Plants Recent Advances In Research And Development written by Hsin-Sheng Tsay and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-25 with Science categories.
Since ancient times, plants have been used as a prime natural source of alternative medicines and have played an important role in our lives. The old tradition of medicinal plant application has turned into a highly profitable business in the global market, resulting in the release of a large number of herbal products. People have tried to find different sources of medicines to alleviate pain and cure different illnesses. Due to severe constraints of synthetic drugs and the increasing contraindications of their usage, there is a growing interest world over in the usage of natural products based on medicinal herbs, hence, there is an ever expanding market of herbs and herbal based medicinal preparations all over the world. This has culminated into an exponential increase in number of research groups in different geographical locations and generation of volume of research data in the field in a short span of time. The path breaking advancement in research methods and interdisciplinary approaches is giving birth to newer perspectives. Therefore, it becomes imperative to keep pace with the advancement in research and development in the field of medicinal herbs. There are a large number of researchers in different parts of the world working on various aspects of medicinal plants and ‘herbal medicines’. The idea is to bring their recent research work into light in the form of a book. The proposed book contains chapters by the eminent researchers in different countries and working with different disciplines of medicinal plants. Articles pertain to different disciplines such as: 1. Resources and conservation of medicinal plants 2. Biosynthesis and metabolic engineering of medicinal plants 3. Tissue culture, propagation and bioreactor technology of medicinal plants 4. Phytochemical research on medicinal plants 5. Herbal medicines and plant-derived agents in cancer prevention and therapy 6. Herbal medicines and plant-derived agents in metabolic syndrome management 7. Herbal medicines and plant-derived agents in modulation of immune-related disorders 8. Herbal medicines and hepatotoxicity The book will prove itself an asset for the researchers, professionals and also students in the area of medicinal plants and mechanism of their action.
Natural Products And Neuroprotection
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Author : Cristina Angeloni
language : en
Publisher: MDPI
Release Date : 2020-06-17
Natural Products And Neuroprotection written by Cristina Angeloni and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-17 with Science categories.
Neurodegenerative diseases, including Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis, are the most common pathologies of the central nervous system currently without a cure. They share common molecular and cellular characteristics, including protein misfolding, mitochondrial dysfunction, glutamate toxicity, dysregulation of calcium homeostasis, oxidative stress, inflammation, and ageing, which contribute to neuronal death. Efforts to treat these diseases are often limited by their multifactorial etiology. Natural products, thanks to their multitarget activities, are considered promising alternatives for the treatment of neurodegeneration. This book deals with two different forms of natural products: extracts and isolated compounds. The study of the bioactivity of the extracts is extremely important as many studies have demonstrated the synergistic effect of the combination of different natural products. On the other hand, the investigation of the activity of specifically isolated natural products can be also important to understand their cellular and molecular mechanisms and to define the specific bioactive components in extracts or foods. This book can be considered an important contribution to knowledge of the neuroprotective effect of natural products and presents a great deal of information, related to both the benefits but also the limitations of their use in counteracting neurodegeneration.
Physical Exercise For Human Health
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Author : Junjie Xiao
language : en
Publisher: Springer Nature
Release Date : 2020-04-27
Physical Exercise For Human Health written by Junjie Xiao and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-27 with Medical categories.
This book shares the latest findings on exercise and its benefits in preventing and ameliorating numerous diseases that are of worldwide concern. Addressing the role of exercise training as an effective method for the prevention and treatment of various disease, the book is divided into eleven parts: 1) An Overview of the Beneficial Effects of Exercise on Health and Performance, 2) The Physiological Responses to Exercise, 3) Exercise and Metabolic Diseases, 4) Exercise and Cardiovascular Diseases, 5) Exercise and Musculoskeletal Diseases, 6) Exercise and Neurological and Psychiatric Diseases, 7) Exercise and the Respiration System, 8) Exercise and Immunity, 9) Exercise and HIV/AIDS, 10) Exercise and Neuropsychiatric Disorders, and 11) Future Prospects. Given its scope, the book will be particularly useful for researchers and students in the fields of physical therapy, physiology, medicine, genetics and cell biology, as well as researchers and physicians with a range of medical specialties.
Phytonutrients And Neurological Disorders
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Author : Haroon Khan
language : en
Publisher: Academic Press
Release Date : 2023-07-11
Phytonutrients And Neurological Disorders written by Haroon Khan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-11 with Medical categories.
Phytonutrients and Neurological Disorders: Therapeutic and Toxicological Aspects provides and assesses the latest research and developments surrounding the use of phytonutrients for the treatment of neurological disorders. The volume analyzes advances in phytonutrient isolation, characterization and therapeutic applications, giving particular emphasis to mechanisms and safety profiles. The book takes toxicological considerations into account, including adverse drug reactions, toxicokinetics and toxicodynamics. Sections cover bioactive compound classes and biosynthesis pathways, general considerations, including quality control, standardization, and technology, and toxicology. This title is a comprehensive work on the latest research in phytonutrients and neurological disorders that will be useful to researchers and medical practitioners. Presents a comprehensive resource on phytonutrients and their relationship to neurological disorders Analyzes the isolation, characterization and mechanisms of phytonutrients in neurology Focuses on various signaling pathways followed by phytonutrients in neuroprotection Gives the latest thinking on quality control parameters and specifications for phytonutrient study Considers the toxicology of phytonutrients, including adverse drug reactions, toxicokinetics and toxicodynamics
Tea As A Food Ingredient
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Author : Junfeng Yin
language : en
Publisher: CRC Press
Release Date : 2022-07-29
Tea As A Food Ingredient written by Junfeng Yin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-29 with Technology & Engineering categories.
Tea is one of the most widely consumed beverages worldwide, and tea extract has been used in a variety of food products including beverages, bread, cakes, ice-cream, wine, biscuits, dehydrated fruits, and various meat and dairy products. In recent years, there is growing consumer interest in the tea extract supplemented products. Tea as a Food Ingredient: Properties, Processing, and Health Aspects provides extensive scientific information on the properties of tea foods, chemical properties, formulations, and tea as ingredient to develop new health foods. It describes tea food production, chemical and physical properties, sensory quality, processing technology, and health benefits. Early chapters present information relating to scientific studies on the health benefits of tea, and the latter chapters focus on introducing tea products into foods, which is the major focus of the entire book. Key Features: Covers broad areas such as chemical properties, bioactive components, and health benefits of tea-based foods Focuses on chemical properties of tea foods, processing technologies, functional food products, and health benefits Explains how the addition of tea extract changes the properties of food and consumer sensory perception This book presents current and sound scientific knowledge on the nutritional value and health benefit of the different tea-based food products, and will be beneficial for food science professionals as well as anyone with an interest in tea as a food ingredient and the benefits it can provide.
Neurophytomedicine
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Author : Mithun Singh Rajput
language : en
Publisher: CRC Press
Release Date : 2024-01-29
Neurophytomedicine written by Mithun Singh Rajput and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-29 with Medical categories.
Neurological disorders categorized as neurodegenerative, neuropsychiatric, and neurotraumatic impose a substantial health burden and cause a frail impact on life attributes. The use of synthetic drugs can have undesirable side effects, making neurotherapeutics challenging. Research on neuroprotection aiming for the utilization of safer natural compounds; phytochemicals specifically – is a cutting-edge approach. NeuroPhytomedicine intends to present readers with a wide-ranging and state-of-the-art appearance at the beneficial properties of phytochemicals on various neurological ailments. It additionally contains sections explaining: • Applications of phyto-nanotechnology in neurological ailments, • Phytoconstituents related deep learning and machine learning-based solutions for neurological disorders, • Epigenetic relevance pertaining to modulation by phytochemicals. The goal of NeuroPhytomedicine is to give readers a thorough and up-to-date look at how phytochemicals affect the brain and neurological illnesses in a way that is helpful for research scholars, academicians, scientists, neuroscientists, physicians, and researchers from the pharmaceutical industry.
Fruit And Vegetable Phytochemicals
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Author : Elhadi M. Yahia
language : en
Publisher: John Wiley & Sons
Release Date : 2017-08-25
Fruit And Vegetable Phytochemicals written by Elhadi M. Yahia and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-25 with Technology & Engineering categories.
Now in two volumes and containing more than seventy chapters, the second edition of Fruit and Vegetable Phytochemicals: Chemistry, Nutritional Value and Stability has been greatly revised and expanded. Written by hundreds of experts from across the world, the chapters cover diverse aspects of chemistry and biological functions, the influence of postharvest technologies, analysis methods and important phytochemicals in more than thirty fruits and vegetables. Providing readers with a comprehensive and cutting-edge description of the metabolism and molecular mechanisms associated with the beneficial effects of phytochemicals for human health, this is the perfect resource not only for students and teachers but also researchers, physicians and the public in general.