Electrospray Ionization In Action
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Electrospray Ionization In Action
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Author : Pasquale De Marco
language : en
Publisher: Pasquale De Marco
Release Date : 2025-03-07
Electrospray Ionization In Action written by Pasquale De Marco and has been published by Pasquale De Marco this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-07 with Science categories.
In this comprehensive guide to electrospray ionization mass spectrometry (ESI-MS), readers will embark on a journey into the world of this groundbreaking analytical technique. Discover the fundamental principles and mechanisms that drive ESI-MS, empowering you to harness its unparalleled capabilities for analyzing complex mixtures of compounds. Delve into the intricacies of ESI-MS instrumentation, gaining a thorough understanding of each component's role in the ionization, separation, and detection of analytes. Explore the diverse sample preparation techniques employed in ESI-MS, ensuring optimal performance and accurate results. Unravel the vast array of applications where ESI-MS has revolutionized scientific research and industrial practices. Witness the power of ESI-MS in environmental monitoring, safeguarding our ecosystems from pollutants and contaminants. Explore its vital role in food safety, ensuring the quality and integrity of our food supply. In the realm of clinical chemistry, ESI-MS has transformed disease diagnosis and treatment. Learn how ESI-MS aids in biomarker discovery, enabling early detection and personalized medicine. Delve into the use of ESI-MS in drug discovery and development, accelerating the path to new and effective therapies. Moreover, this guide provides invaluable troubleshooting tips and best practices for ESI-MS, empowering you to overcome common challenges and ensure reliable data acquisition and interpretation. With its comprehensive coverage and accessible writing style, this book is an indispensable resource for scientists, researchers, and students seeking to master the art of ESI-MS. If you like this book, write a review!
Electrospray And Maldi Mass Spectrometry
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Author : Richard B. Cole
language : en
Publisher: John Wiley & Sons
Release Date : 2011-09-26
Electrospray And Maldi Mass Spectrometry written by Richard B. Cole and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-26 with Science categories.
Discover how advances in mass spectrometry are fueling new discoveries across a broad range of research areas Electrospray and MALDI Mass Spectrometry brings both veteran practitioners and beginning scientists up to date with the most recent trends and findings in electrospray ionization and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. In particular, this Second Edition highlights how advances in electrospray and MALDI mass spectrometry are supporting important discoveries in new and emerging fields such as proteomics and metabolomics as well as in traditional areas of chemistry and physics research. Electrospray AND MALDI Mass Spectrometry, SECOND EDITION is divided into five parts: Part A, Fundamentals of ES, explains the fundamental phenomena underlying the electrospray process, including selectivity in ionization and inherent electrochemistry, and concludes with a chapter offering a comparative inventory of source hardware Part B, Fundamentals of MALDI, confronts ionization mechanisms, instrument development, and matrix selection, and includes a final chapter that explores the special application of MALDI to obtain two-dimensional images of spatial distributions of compounds on surfaces Part C, ES and MALDI Coupling to Mass Spectrometry Instrumentation, examines the coupling of these ionization techniques to various mass analyzers, including quadrupole ion trap, time-of-flight, Fourier transform ion cyclotron resonance, and ion mobility mass spectrometers Part D, Practical Aspects of ES and MALDI, investigates analytical issues including quantification, charge-state distributions, noncovalent interactions in solution that are preserved as gas-phase ions, and various means of ion excitation in preparation for tandem mass spectrometry, and offers a guide to the interpretation of even-electron mass spectra Part E, Biological Applications of ES and MALDI, examines the role of mass spectrometry in such areas as peptide and protein characterization, carbohydrate analysis, lipid analysis, and drug discovery Written by a team of leading experts, the book not only provides a critical review of the literature, but also presents key concepts in tutorial fashion to help readers take full advantage of the latest technological breakthroughs and applications. As a result, Electrospray and MALDI Mass Spectrometry will help researchers fully leverage the power of electrospray and MALDI mass spectrometry. The judicious compartmentalization of chapters, and the pedagogic presentation style throughout, render the book highly suitable for use as a text for graduate-level courses in advanced mass spectrometry.
Reactive Intermediates
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Author : Leonardo S. Santos
language : en
Publisher: Wiley-VCH
Release Date : 2010-02-01
Reactive Intermediates written by Leonardo S. Santos and has been published by Wiley-VCH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-02-01 with Science categories.
Edited by a top expert, this book represents a powerful tool showing how to successfully apply ESI-MS in revealing, elucidating and helping to consolidate several proposed mechanisms of organic reactions that need to be emphasized. With a foreword by Chris Enke
Ambient Ionization Mass Spectrometry
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Author : Marek Domin
language : en
Publisher: Royal Society of Chemistry
Release Date : 2014-11-25
Ambient Ionization Mass Spectrometry written by Marek Domin and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-25 with Science categories.
Ambient ionization has emerged as one of the hottest and fastest growing topics in mass spectrometry enabling sample analysis with minimal sample preparation. Introducing the subject and explaining the basic concepts and terminology, this book will provide a comprehensive, unique treatise devoted to the subject. Written by acknowledged experts, there are full descriptions on how new ionization techniques work, with an overview of their strengths, weaknesses and applications. This title will bring the reader right up to date, with both applications and theory, and will be suitable as a tutorial text for those starting in the field from a variety of disciplines.
Encyclopedia Of Spectroscopy And Spectrometry
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Author :
language : en
Publisher: Academic Press
Release Date : 2016-09-22
Encyclopedia Of Spectroscopy And Spectrometry written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-22 with Science categories.
This third edition of the Encyclopedia of Spectroscopy and Spectrometry, Three Volume Set provides authoritative and comprehensive coverage of all aspects of spectroscopy and closely related subjects that use the same fundamental principles, including mass spectrometry, imaging techniques and applications. It includes the history, theoretical background, details of instrumentation and technology, and current applications of the key areas of spectroscopy. The new edition will include over 80 new articles across the field. These will complement those from the previous edition, which have been brought up-to-date to reflect the latest trends in the field. Coverage in the third edition includes: Atomic spectroscopy Electronic spectroscopy Fundamentals in spectroscopy High-Energy spectroscopy Magnetic resonance Mass spectrometry Spatially-resolved spectroscopic analysis Vibrational, rotational and Raman spectroscopies The new edition is aimed at professional scientists seeking to familiarize themselves with particular topics quickly and easily. This major reference work continues to be clear and accessible and focus on the fundamental principles, techniques and applications of spectroscopy and spectrometry. Incorporates more than 150 color figures, 5,000 references, and 300 articles for a thorough examination of the field Highlights new research and promotes innovation in applied areas ranging from food science and forensics to biomedicine and health Presents a one-stop resource for quick access to answers and an in-depth examination of topics in the spectroscopy and spectrometry arenas
Mass Spectrometry
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Author : Jürgen H Gross
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-05
Mass Spectrometry written by Jürgen H Gross and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-05 with Science categories.
Mass Spectrometry is an ideal textbook for students and professionals as well as newcomers to the field. Starting from the very first principles of gas-phase ion chemistry and isotopic properties, the textbook takes the reader through the design of mass analyzers and ionization methods all the way to mass spectral interpretation and coupling techniques. Step-by-step, the reader learns how mass spectrometry works and what it can do. The book comprises a balanced mixture of practice-oriented information and theoretical background. It features a clear layout and a wealth of high-quality figures. Exercises and solutions are located on the Springer Global Web.
Essentials Of Pharmaceutical Analysis
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Author : Muhammad Sajid Hamid Akash
language : en
Publisher: Springer Nature
Release Date : 2019-12-17
Essentials Of Pharmaceutical Analysis written by Muhammad Sajid Hamid Akash and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-17 with Medical categories.
Recent advances in the pharmaceutical sciences and biotechnology have facilitated the production, design, formulation and use of various types of pharmaceuticals and biopharmaceuticals. This book provides detailed information on the background, basic principles, and components of techniques used for the analysis of pharmaceuticals and biopharmaceuticals. Focusing on those analytical techniques that are most frequently used for pharmaceuticals, it classifies them into three major sections and 19 chapters, each of which discusses a respective technique in detail. Chiefly intended for graduate students in the pharmaceutical sciences, the book will familiarize them with the components, working principles and practical applications of these indispensable analytical techniques.
Introduction To Mass Spectrometry
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Author : J. Throck Watson
language : en
Publisher: John Wiley & Sons
Release Date : 2013-07-09
Introduction To Mass Spectrometry written by J. Throck Watson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-09 with Science categories.
Completely revised and updated, this text provides an easy-to-read guide to the concept of mass spectrometry and demonstrates its potential and limitations. Written by internationally recognised experts and utilising "real life" examples of analyses and applications, the book presents real cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analysers and ionisation, along with corresponding strategies for interpretation of data. The book concludes with a comprehensive 3000 references. This multi-disciplined text covers the fundamentals as well as recent advance in this topic, providing need-to-know information for researchers in many disciplines including pharmaceutical, environmental and biomedical analysis who are utilizing mass spectrometry
Electrospray Ionization Mass Spectrometry
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Author : Richard B. Cole
language : en
Publisher: Wiley-Interscience
Release Date : 1997-05-06
Electrospray Ionization Mass Spectrometry written by Richard B. Cole and has been published by Wiley-Interscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-05-06 with Science categories.
Comprehensive, up-to-date coverage of a revolutionary technique Electrospray ionization mass spectrometry (ESI-MS) has completely changed the way physicists, chemists, and biologists view the study of large molecules. The technique derives detailed information about molecular weights and structures from extremely small sample quantities. ESI-MS can create highly charged forms of very high molecular weight compounds, it is naturally compatible with many types of separation techniques, and it allows noncovalent interactions between molecules in solution to be preserved in the gas phase. But many researchers may not use the technique to its full potential because they are unfamiliar with the different perspectives of its underlying processes, the varied approaches to implementation, and the wide-ranging utility of the technique. In this book, Richard B. Cole and an assemblage of leading researchers present a single-volume compilation of different approaches to the understanding and exploitation of ESI-MS. This comprehensive guide: * Examines the physical and chemical aspects of the electrospray process and describes the events involved in ion formation as well as the electro-chemical phenomena that are central to charged droplet formation during the process * Explores the coupling of electrospray ionization to various mass spectrometers, including quadrupole, magnetic, time-of-flight, quadrupole ion trap, and Fourier transform ion cyclotron resonance instruments * Describes recent progress in interfacing ESI with solution-based separation techniques, including liquid chromatography and capillary electrophoresis * Charts the rapid development of ESI applications and categorizes them by compound type: peptides and proteins, nucleic acids and their constituents, carbohydrates and lipids, small molecules related to pharmacology and drug metabolism, and organometallics and inorganic compounds Electrospray Ionization Mass Spectrometry is the indispensable handbook and reference for anyone who wishes to understand, implement, or apply this technique, including researchers in chemistry, metallochemistry, biochemistry, biology, pharmacology, and physics.
Analytical And Physical Electrochemistry
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Author : Hubert H. Girault
language : en
Publisher: CRC Press
Release Date : 2004-10-25
Analytical And Physical Electrochemistry written by Hubert H. Girault and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-10-25 with Science categories.
The study of electrochemistry is pertinent to a wide variety of fields, including bioenergetics, environmental sciences, and engineering sciences. In addition, electrochemistry plays a fundamental role in specific applications as diverse as the conversion and storage of energy and the sequencing of DNA. Intended both as a basic course for un