Emerging Talents In Frontiers In Pharmacology Gastrointestinal And Hepatic Pharmacology 2022
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Emerging Talents In Frontiers In Pharmacology Gastrointestinal And Hepatic Pharmacology 2022
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Author : Laura Grasa
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-25
Emerging Talents In Frontiers In Pharmacology Gastrointestinal And Hepatic Pharmacology 2022 written by Laura Grasa and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-25 with Science categories.
Network Pharmacology
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Author : Shao Li
language : en
Publisher: Springer Nature
Release Date : 2021-09-29
Network Pharmacology written by Shao Li and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-29 with Medical categories.
This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.
Herbal Medicines For Gastrointestinal And Hepatic Diseases Novel Pharmacological And Toxicological Approaches Volume I 2nd Edition
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Author : Muhammad Hasnat,
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-21
Herbal Medicines For Gastrointestinal And Hepatic Diseases Novel Pharmacological And Toxicological Approaches Volume I 2nd Edition written by Muhammad Hasnat, and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-21 with Science categories.
This Research Topic is part of a series with: Herbal Medicines for Gastrointestinal and Hepatic Diseases - Novel Pharmacological and Toxicological approaches, Volume II Ethnopharmacology deals with the exchange of knowledge about people's use of herbal medicines and their pharmacological effects. The information related to therapeutic agents of plant origin and their toxic effects was preserved by oral tradition as well as recorded in materia medica. Many drugs that are now available on the market have been developed from this valuable information. Today, scientists that specialize in medicinal chemistry use these existing herbal drugs to develop and produce more therapeutically active agents with less toxic side effects. The gastrointestinal tract (GIT) is a multi-organ system, consisting of bacteria, and digestive enzymes that have the capacity of degrading food and other molecules. Diseases associated with this organ system include peptic ulcer, inflammatory bowel disease, gastric cancer to name a few. The liver receives seventy percent of its blood supply from the GIT via the hepatic portal vein. The disruption in the gut–liver axis is associated with liver diseases including alcohol-associated liver disease (ALD), non-alcoholic fatty liver disease (NAFLD), and autoimmune liver disease (AILD). NAFLD can cause non-alcoholic steatohepatitis, which can develop into liver cirrhosis through inflammation and fibrosis. Liver cirrhosis is categorized as an end-stage of chronic liver disease, which impairs innate immunity-related genes. Growing evidence from preclinical studies proposes that the gut–liver axis leads to targeted therapeutic modalities for various liver injuries. Therefore, therapeutic treatment of these conditions is essential to prevent progression to these more harmful late-stage diseases.
Network Pharmacology And Traditional Medicine Setting The New Standards By Combining In Silico And Experimental Work
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Author : Shao Li
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-24
Network Pharmacology And Traditional Medicine Setting The New Standards By Combining In Silico And Experimental Work written by Shao Li and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-24 with Science categories.
Patient Derived Tumor Xenograft Models
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Author : Rajesh Uthamanthil
language : en
Publisher: Academic Press
Release Date : 2016-10-13
Patient Derived Tumor Xenograft Models written by Rajesh Uthamanthil and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-13 with Medical categories.
Patient Derived Tumor Xenograft Models: Promise, Potential and Practice offers guidance on how to conduct PDX modeling and trials, including how to know when these models are appropriate for use, and how the data should be interpreted through the selection of immunodeficient strains. In addition, proper methodologies suitable for growing different type of tumors, acquisition of pathology, genomic and other data about the tumor, potential pitfalls, and confounding background pathologies that occur in these models are also included, as is a discussion of the facilities and infrastructure required to operate a PDX laboratory. Offers guidance on data interpretation and regulatory aspects Provides useful techniques and strategies for working with PDX models Includes practical tools and potential pitfalls for best practices Compiles all knowledge of PDX models research in one resource Presents the results of first ever global survey on standards of PDX development and usage in academia and industry
Yi Lin Gai Cuo
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Author : Qingren Wang
language : en
Publisher: Blue Poppy Enterprises, Inc.
Release Date : 2007
Yi Lin Gai Cuo written by Qingren Wang and has been published by Blue Poppy Enterprises, Inc. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
New Insights Into Renal Fibrosis And Therapeutic Effects Of Natural Products Volume Ii
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Author : Dan-Qian Chen
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-19
New Insights Into Renal Fibrosis And Therapeutic Effects Of Natural Products Volume Ii written by Dan-Qian Chen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-19 with Science categories.
Chinmedomics
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Author : Xijun Wang
language : en
Publisher: Academic Press
Release Date : 2015-07-15
Chinmedomics written by Xijun Wang and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-15 with Science categories.
Chinmedomics: The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine uses new experimental techniques and research to open doors in drug discovery and development related to traditional Chinese medicine (TCM). This book features a unique approach that combines chemometric analysis with metabolomics studies to illuminate significant changes that have occurred in syndrome states while simultaneously analyzing the efficacy of chemical ingredients in herbal medicines. Chapters provide cutting-edge information on traditional medicine, analytical technology, natural products, metabolomics, bioinformatics and their applications. This book provides a valuable resource for pharmacologists, pharmaceutical scientists, medicinal plant researchers, pharmacognosists and chemists working with TCM and highlights ways to further research and advances in this area in the future. Presents a practical guide for new practitioners of Chinmedomics with insights on the current use and future development of this method Each chapter includes an introduction, method, references to the latest literature, possible mechanisms of action and applications Edited by the leading experts of research related to Chinmedomics
Ranunculales Medicinal Plants
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Author : Da-Cheng Hao
language : en
Publisher: Academic Press
Release Date : 2018-04-23
Ranunculales Medicinal Plants written by Da-Cheng Hao and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-23 with Medical categories.
Ranunculales Medicinal Plants: Biodiversity, Chemodiversity and Pharmacotherapy comprehensively covers this order of flowering plants, detailing the phytochemistry, chemotaxonomy, molecular biology, and phylogeny of selected medicinal plants families and genera and their relevance to drug efficacy. The book carries out an exhaustive survey of the literature in order to characterize global trends in the application of flexible technologies. The interrelationship between Chinese species, and between Chinese and non-Chinese species, is inferred through molecular phylogeny and based on nuclear and chloroplast DNA sequencing. The book discusses the conflict between chemotaxonomy and molecular phylogeny in the context of drug discovery and development. Users will find invaluable and holistic coverage on the study of Ranunculales that will make this the go-to pharmaceutical resource. Describes current perceptions of biodiversity and chemodiversity of Ranunculales Explains how the conceptual framework of plant pharmacophylogeny benefits the sustainable exploitation of Ranunculales Details how Ranunculales medicinal plants work from the chemical level upward Covers how the polypharmacology of Ranunculales compounds might inspire new chemical entity design and development for improved treatment outcomes
Ethnopharmacological Responses To The Coronavirus Disease 2019 Covid 19 Pandemic
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Author : Michael Heinrich
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-20
Ethnopharmacological Responses To The Coronavirus Disease 2019 Covid 19 Pandemic written by Michael Heinrich and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-20 with Science categories.