Emerging Targets In Antibacterial And Antifungal Chemotherapy
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Emerging Targets In Antibacterial And Antifungal Chemotherapy
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Author : Joyce Sutcliffe
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Emerging Targets In Antibacterial And Antifungal Chemotherapy written by Joyce Sutcliffe and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Emerging Targets in Antibacterial and Antifungal Chemotherapy offers constructive ideas to researchers that could lead to the discovery of entirely new classes of drugs. The authors emphasize new topics rather than review work on known antibacterials and antifungals, and identify new targets--either the rate-limiting component of a biochemical pathway or a component of the pathway that is susceptible to a ``screening'' or ``rational drug design'' approach. Each chapter reviews the biochemical pathway and its place in the cellular scheme in order to place the target in perspective. The authors, a mixture of academic researchers and drug-discovery investigators in pharmaceutical companies, also extend these theoretical concerns into practical applications and suggest useful screening methodologies. The importance of this subject area is demonstrated by the increasing number of papers in the literature that point to potential targets and screening methodologies for new antibacterials. This book also deals with antifungals, investigating the inherent limitations in existing antifungals (many of which are extremely toxic or have only limited efficacy), and pointing to major developments in the discovery of novel antifungals. Emerging Targets in Antibacterial and Antifungal Chemotherapy will be of interest to professional microbiologists, biochemists, and cell biologists in both academic and industrial laboratories.
Antimicrobial Drug Discovery
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Author : George Tegos
language : en
Publisher: CABI
Release Date : 2012
Antimicrobial Drug Discovery written by George Tegos and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
Resistance is on the rise among a variety of human pathogenic microorganisms associated with common and potentially life-threatening infections, including penicillin-resistant Streptococcus pneumonia and Methicillin-resistant Staphylococcus aureus (MRSA). There is increasing demand to approach the threat of multidrug resistance incorporating novel multidisciplinary methodologies and technological platforms. This book documents the latest research, covering current and promising activities in four key areas: computational chemistry and chemoinformatics, High Throughput Screening (HTS), non-vertebrate model hosts and light and nano-based technologies. It is essential reading for researchers and students in microbiology, biotechnology, pharmacology, chemistry and biology as well as medical professionals.
Treating Infectious Diseases In A Microbial World
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2006-01-03
Treating Infectious Diseases In A Microbial World written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-03 with Medical categories.
Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.
Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1992
Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Medicine categories.
First multi-year cumulation covers six years: 1965-70.
Biological Inhibitors
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Author : M. Iqbal Choudhary
language : en
Publisher: CRC Press
Release Date : 2020-08-18
Biological Inhibitors written by M. Iqbal Choudhary and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-18 with Business & Economics categories.
This book, a part of the series Studies in Medicinal Chemistry, details the biological inhibitors that reflect drug discovery in treating human diseases, including cardiovascular, nervous, inflammatory, hormonal and metabolic processes. Compounds for fungal diseases and HIV/AIDS are also covered.
Plant Derived Antimycotics
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Author : M.k. Rai
language : en
Publisher: CRC Press
Release Date : 2003-05-29
Plant Derived Antimycotics written by M.k. Rai and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-05-29 with Science categories.
An important overview of the state of the art in naturally occurring antimycotics! Here is a comprehensive and innovative examination of the antimycotic potential of essential plant oils and extracts against fungal infections affecting humans, animals, plants, and foodstuffs. Plant-Derived Antimycotics emphasizes the antimycotic activity of plants found in Central America, India, Nepal, Fiji, and China--areas rich in phyto-diversity and traditional botanical/medical knowledge. From editor M.K. Rai: “Since the inception of human civilization men have been using herbs against various mycotic infections. In the recent past, several antimycotic agents have been introduced into the market due to their rapid curative properties. Still, the quest for new antifungal agents of a fungicidal rather than fungistatic nature continues. Furthermore, there has been a dramatic increase in the new spectrum of fungal infections known as opportunistic fungal pathogens. Consequently, plant-derived antimycotics are gaining importance, being natural, cheaper, safer, eco-friendly, and within the reach of the common man.” With a distinguished list of contributors from around the world, Plant-Derived Antimycotics explores: antifungal compounds that strengthen plant-defense systems traditional herbs that have revealed their antifungal properties newer, faster methods of screening and evaluating antifungal drugs natural antimycotics derived from plants in Croatia, South America, South Africa, China, India, and Fiji the mechanism of herbal antimycotic action the diversity of antimycotic efficacy in Asteraceous and Meliaceous plants new bioactive antifungal molecules Plant-Derived Antimycotics is an essential reference for pharmacologists, microbiologists, clinical mycologists, oncologists, immunologists, drug manufacturers, botanists and ethnobotanists, phytochemists, herbalists, and everyone searching for a natural remedy for the new spectrum of opportunistic fungal infections generated by the immunocompromising difficulties encountered by AIDS and cancer patients. Color illustrations, photographs, charts, tables, and graphs make the information easier to absorb and understand.
Fungal Biotechnology In Agricultural Food And Environmental Applications
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Author : Dilip K. Arora
language : en
Publisher: CRC Press
Release Date : 2003-12-17
Fungal Biotechnology In Agricultural Food And Environmental Applications written by Dilip K. Arora and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-12-17 with Science categories.
Contributions from 80 world-renowned authorities representing a broad international background lend Fungal Biotechnology in Agricultural, Food, and Environmental Applicationsfirst-class information on the biotechnological potential of entomopathogenic fungi and ergot alkaloids, applications of Trichoderma in disease control, and the development of mycoherbicides. Additional topics include fungal control of nematodes, control of plant disease by arbuscular mycorrhizal fungi, strategies for controlling vegetable and fruit crops, molecular biology tactics with mycotoxigenic fungi and the development of biofungicides, production of edible fungi, fermented foods, and high-value products like mycoprotein.
Annual Reports In Medicinal Chemistry
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Author :
language : en
Publisher: Academic Press
Release Date : 1997-10-08
Annual Reports In Medicinal Chemistry written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-10-08 with Science categories.
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expectedto provide the basis for entirely new future therapies.
Antifungal Chemotherapy
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Author : D. C. E. Speller
language : en
Publisher: John Wiley & Sons
Release Date : 1980
Antifungal Chemotherapy written by D. C. E. Speller and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Medical categories.
Discovery Of Novel Natural Products With Therapeutic Potential
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Author : Vincent P. Gullo
language : en
Publisher: Newnes
Release Date : 2013-10-22
Discovery Of Novel Natural Products With Therapeutic Potential written by Vincent P. Gullo and has been published by Newnes this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.
Although science has discovered effective drugs for many of the diseases that afflict mankind, many human health problems remain untreatable. The search for novel therapeutic agents is always ongoing. This book will describe some of the diverse sourcesof natural products, such as terrestrial and marine environments; and will review how research has increased knowledge of biological systems and human disease, leading to the design of targeted asssays, amenable to high volume screening.