Endocrine Autoimmunity And Associated Conditions
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Endocrine Autoimmunity And Associated Conditions
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Author : A.P. Weetman
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Endocrine Autoimmunity And Associated Conditions written by A.P. Weetman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Autoimmunity is the most common cause of endocrine disorders. This volume provides an up-to-date summary of recent advances in this important field. In addition, it describes developments in our understanding of conditions such as vitiligo and pernicious anaemia which are frequently associated with autoimmune endocrinopathies. There is a detailed review of animal models of endocrine disease which have contributed greatly to current knowledge. Furthermore, the aetiology, pathogenesis and treatment of the clinical disorders are discussed in depth. The book will be of interest to anyone working in the areas of endocrinology and immunology.
Endocrine Immunology
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Author : W. Savino
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2017-02-28
Endocrine Immunology written by W. Savino and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-28 with Medical categories.
In the last decades, several in vitro and in vivo studies have revealed the existence of a very complex network between the neuroendocrine and immune system. Important molecular mechanisms underlying these interactions, in both physiological and pathological conditions, have also been described. Indeed, hormones play a pivotal role in the development and functional regulation of the immune system – both innate and acquired responses. Immune system cells present specific hormone receptors and themselves produce some hormones, thus influencing hormone secretion. More recently, the modulation of hormone secretion has been attempted for treating associated autoimmune disorders, further supporting the strong interplay between the endocrine and immune system. Distinguished experts, who have published extensively in their fields, have contributed comprehensive chapters to this volume. The focus is on the various aspects of endocrine-neuro-immune connections, providing an updated panorama - from basics to clinical applications - of current knowledge and still debated issues.
Thyroid Autoimmunity
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Author : A. Pinchera
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Thyroid Autoimmunity written by A. Pinchera and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In 1956, three groups independently reported evidence that some thyroid disease appearing spontaneously in humans or experimentally induced in animals are related to autoimmune processes. The interval between these landmark discoveries and the present has witnessed a remarkable and continuing growth of both knowledge and concepts concerning the mechanisms of immune regulation, the pathogenesis of autoimmune thyroid diseases, and their clinical and laboratory manifestations. More importantly knowledge of thyroid autoimmunity has, in many respects, comprised the vanguard of an ever increasing appreciation and understanding of autoimmune diseases in general. On November 24-26 1986, an International Symposium on Thyroid Autoimmunity was held in Pisa. Its purpose was to commemorate the birth of thyroid autoimmunity as a scientific discipline, to summarize current knowledge and concepts in this area, and where possible, to anticipate areas of opportunity for the future - hence the theme of the Symposium, Memories and Perspectives. To open the meeting, the Magnifico Rettore (Chancellor) of the University of Pisa granted special Awards to Dr. Deborah Doniach, Dr. Ivan Roitt, and Dr. Noel R. Rose, who published the first fundamental studies in the field of thyroid autoimmunity, and to Dr. Duncan G. Adams, whose discovery of the long-acting thyroid stimulator (LATS) opened the door to our current understanding of the pathogenesis of Graves' disease. During the meeting thirty plenary lectures were presented.
Paediatric Thyroidology
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Author : G. Szinnai
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2014-09-15
Paediatric Thyroidology written by G. Szinnai and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-15 with Medical categories.
This book presents a comprehensive overview of pediatric thyroid diseases and thus provides a useful tool for clinical problem solving. Opinion leaders in the field present reviews on all relevant diseases of the hypothalamic-pituitary-thyroid axis. Sixteen chapters cover topics ranging from fetal thyroidology, congenital hypothyroidism, central hypothyroidism, inherited defects of thyroid hormone action, cell transport and metabolism to iodine deficiency, autoimmune thyroid disease and thyroid tumors. Written by clinicians, the chapters provide in-depth information and current guidelines for clinical problems encountered in pediatric thyroidology. As a unique feature, a case seminar collection for each chapter presents typical patient histories providing key learning points and key references for clinical problem solving in family medicine, pediatric endocrinology and medical genetics. Providing a succinct update on clinical pediatric thyroidology, this book is an essential tool for pediatric and adult endocrinologists, as well as for general practitioners, pediatricians and medical geneticists.
Autoantibodies
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Author : J.B. Peter
language : en
Publisher: Elsevier
Release Date : 1996-07-17
Autoantibodies written by J.B. Peter and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-07-17 with Medical categories.
This volume is THE definitive, completely up-to-date, reference work for ALL researchers and clinicians working in autoimmunity.Up-to-Date: This is a timely critical review of more than 100 autoantibodies by leading experts in their respective fields, and includes many recent references.International Experts: The 120 Chapters have been written by the top international cadre of authors who have provided structured, expert contributions.Comprehensive: A total comprehensive perspective on the processes which induce, inhibit or otherwise affect autoantibodies in humans.Useful to Researchers and Clinicians: Chapters generally include methods of detection, pathogenic role, factors in pathogenicity and genetics as well as clinical utility with disease associations and frequencies.
Diagnostic Criteria In Autoimmune Diseases
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Author : Yehuda Shoenfeld
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-06-08
Diagnostic Criteria In Autoimmune Diseases written by Yehuda Shoenfeld and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-08 with Medical categories.
According to the Autoimmune Diseases Coordinating Committee (ADCC), between 14.7 and 23.5 million people in the USA – up to eight percent of the population are affected by autoimmune disease. Autoimmune diseases are a family of more than 100 chronic, and often disabling, illnesses that develop when underlying defects in the immune system lead the body to attack its own organs, tissues, and cells. In Handbook of Autoimmune Disease, the editors have gathered in a comprehensive handbook a critical review, by renowned experts, of more than 100 autoimmune diseases, divided into two main groups, namely systemic and organ-specific autoimmune diseases. A contemporary overview of these conditions with special emphasis on diagnosis is presented. Each chapter contains the essential information required by attending physicians as well as bench scientists to understand the definition of a specific autoimmune disease, the diagnostic criteria, and the treatment.
Autoimmune Diseases In Endocrinology
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Author : Anthony P. Weetman
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-12-26
Autoimmune Diseases In Endocrinology written by Anthony P. Weetman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-26 with Medical categories.
Autoimmune Diseases in Endocrinology is a comprehensive and novel text that examines key features that predispose individuals to autoimmune diseases. The text begins with three introductory chapters which provide sufficient information so that anyone, including those without a background in recent immunology, will be able to understand the developments in the field. The next and largest section of the book concerns autoimmune thyroid disease, and authors of these chapters take the reader through the basic epidemiology, genetic and environmental risk factors, immunopathogenesis, and the diagnostic and management aspect of the disease. The next section discusses Type 1 diabetes mellitus. In the final section, authors explain other autoimmune endocrinopathies, including Addison’s disease, premature ovarian failure, autoimmune hypophysitis, and autoimmune polyglandular syndrome types 1 and 2. Comprehensive and timely, Autoimmune Diseases in Endocrinology will become an essential reference for all endocrinologists and internal medicine practitioners working in this field.
Rheumaderm
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Author : Carmel Mallia
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Rheumaderm written by Carmel Mallia and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This book represents the proceedings of a conference, Rheumaderm, that was held in December 1997. The meeting was a dialogue between the specialties of Rheumatology and Dermatology, exploring and discussing areas of common interest. The aim was to present problems common to both specialties, thereby emphasising the team approach to such problems and helping to combine various skills.
Autoimmune Diseases Of The Endocrine System
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Author : Robert Volpe'
language : en
Publisher: CRC Press
Release Date : 1990-10-05
Autoimmune Diseases Of The Endocrine System written by Robert Volpe' and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-10-05 with Medical categories.
This book is a comprehensive, easy-to-read discussion of the organ-specific autoimmune endocrine diseases emphasizing new contributions and trends for research and management. It begins with a brief chapter introducing the general principles of immunology, followed by discussions covering topics such as immunogenetics and animal models and how they can be applied toward interpreting human autoimmune endocrine diseases, autoimmune thyroid diseases, insulin-dependent diabetes mellitus hypophysitis, and Addison's disease. The book also discusses future trends toward gaining an understanding of these disorders and possible therapeutic principles. It is well-illustrated and will prove to be a useful reference source for internists, endocrinologists, and postgraduate students interested in human autoimmune endocrine diseases.
B Cell Receptor Signaling
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Author : Tomohiro Kurosaki
language : en
Publisher: Springer
Release Date : 2015-12-26
B Cell Receptor Signaling written by Tomohiro Kurosaki and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-26 with Medical categories.
This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.