Endocrine Disruptors Brain And Behavior
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Endocrine Disruptors Brain And Behavior
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Author : Heather B. Patisaul
language : en
Publisher: Oxford University Press
Release Date : 2017-04-10
Endocrine Disruptors Brain And Behavior written by Heather B. Patisaul and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-10 with Psychology categories.
Our world and bodies are becoming increasingly polluted with chemicals capable of interfering with our hormones and thus, possibly, our present and future neural and mental health. As authors Heather Patisaul and Scott Belcher outline, there is a large lack of data and evidence in this causal relationship, which begs a need for further study to accelerate progress in the endocrinology and neuroendocrinology fields. Endocrine Disruptors, Brain, and Behavior focuses on if and how these chemicals, known as endocrine disrupting compounds (EDCs), affect the development and function of the brain and might be contributing to neural disorders rapidly rising in prevalence. The book provides an overall synthesis of the EDC field, including its historical roots, major hypotheses, key findings, and research gaps. The authors explain why even the concept of endocrine disruption is controversial in some circles, how differing definitions of endocrine disruption and what constitutes an "adverse" outcome on the brain shape public policy, and where the current capacity by different stakeholders (industry, academia, regulatory agencies) to evaluate chemicals for safety in a regulatory context begins and ends. The book concludes with suggestions for future research needs and a summary of emerging technology which might prove capable of more effectively evaluating existing and emerging chemicals for endocrine disrupting properties. As such, it provides the context for interdisciplinary and innovative input from a broad spectrum of fields, including those well-schooled in neuroscience, evolutionary biology, brain, behavior, sex differences, and neuroendocrinology.
Endocrine Disruptors And The Developing Brain
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Author : Andrea C. Gore
language : en
Publisher: Morgan & Claypool Publishers
Release Date : 2012
Endocrine Disruptors And The Developing Brain written by Andrea C. Gore and has been published by Morgan & Claypool Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
The field of endocrine disruption has been the focus of increasing attention from scientists and the general public in the past 30 years, amidst concerns that exposure to environmental chemicals with the potential to alter endocrine system function, known as endocrine disrupting chemicals (EDCs), may be contributing to an overall decline in wildlife populations and the reproductive health of humans. These concerns are based on observations of adverse effects of EDCs on marine and land animals, an increased incidence of reproductive and endocrine disease in humans, epidemiological evidence for links between body burden and disease, and endocrine disruption in laboratory animals following exposure to EDCs. Owing to its role in regulation of endocrine function as well as its responsiveness to hormones, the developing brain is an especially vulnerable target for many classes of EDCs. This book will address the evidence for EDC action on the developing brain, organized into 7 chapters. Topics covered include background about EDCs, evidence for exposures, concerns about EDC effects in the developing organism, and particularly on the developing nervous system, how EDCs perturb the brain's neuroendocrine systems, transgenerational epigenetic effects of EDCs, EDC effects on non-reproductive behaviors, and future perspectives. This is the first book completely dedicated to understanding links between EDCs and the developing brain, an area of emerging importance for human health. Table of Contents: What Are Environmental Endocrine-Disrupting Chemicals (EDCs)? / EDC Exposures / EDCs and Development / EDCs and the Developing Brain / EDCs and Neuroendocrine Systems / Epigenetic Effects of EDCs / EDCs, the Brain, and the Future / Acknowledgments / References / Author Biographies
Hormones Brain And Behavior
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Author :
language : en
Publisher:
Release Date : 2002
Hormones Brain And Behavior written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Endocrinology categories.
Endocrine Disrupting Chemicals
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Author : Andrea C. Gore
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-06-08
Endocrine Disrupting Chemicals written by Andrea C. Gore and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-06-08 with Medical categories.
This book provides comprehensive coverage of the three most important themes in the field of Endocrine Disrupting Chemicals (EDC) research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs.
Hormone Behavior Relations Of Clinical Importance
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Author : Robert H. Rubin
language : en
Publisher: Academic Press
Release Date : 2010-03-16
Hormone Behavior Relations Of Clinical Importance written by Robert H. Rubin and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-16 with Medical categories.
A single volume of 41 articles, Hormone/Behavior Relations of Clinical Importance is an authoritative selection of relevant chapters from the Hormones Brain and Behavior 2e MRW, the most comprehensive source of neuroendocrinological information assembled to date (AP July 2009). The study of hormones as they impact the brain and, subsequently, behavior is a central topic in neuroscience, endocrinology and psychiatry. This volume offers an overview of neuroendocrinological topics, approaching the subject from the perspective of hormone-brain function, hormone-behavior relations, sex differences, and the impact on various diseases/pathologies. Many basic human behavioral functions are subject to the influence of hormones - sexual orientation, the experience of pain, fertility, immunity - as are clinical conditions such as diabetes, substance abuse disorder, eating disorders, PTSD, TBI, pain, Alzheimer's, stress/anxiety, affective disorders, and more. There is considerable commercial clinical potential in the study of hormones - drug companies are currently developing a Cholecystokinin (hormonal peptide) booster to reduce appetite in those who suffer from sever obesity, and catamenial epilepsy (features seizure exacerbation in relation to the menstrual cycle) is resistant to treatment by standard antiepileptic medications, but may be hormonally controlled. These issues and more are covered, and there is simply no other current single-volume reference with such comprehensive coverage and depth. Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 150 figures (50 in color). A collection of articles reviewing our fundamental knowledge of neuroendocrinology, the book provides an essential, affordable reference for researchers, clinicians and graduate students in the area. - Offering outstanding scholarship, each chapter is written by an expert in the topic area and approximately 25% of chapters are written by international contributors (7 countries represented) - Provides more fully vetted expert knowledge than any existing work with broad appeal for the US, UK and Europe, accurately crediting the contributions to research in those regions - Heavily illustrated with 150 figures, approximately 50 in color, presenting the material in the most visually useful form for the reader - Fully explores various clinical conditions associated with the hormones and the brain (PTSD, TBI, Stress & Anxiety, eating disorders, diabetes, addictive disorders, Alzheimer's, affective disorders) - Broad coverage of disorders makes the volume relevant to clinicians as well as researchers and basic scientists
Endocrine Disruptors And Puberty
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Author : Evanthia Diamanti-Kandarakis
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-12-01
Endocrine Disruptors And Puberty written by Evanthia Diamanti-Kandarakis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-01 with Medical categories.
Endocrine disruption represents one of the most controversial environmental issues of our time. Mounting evidence stemming from more than 10 years of experimental, epidemiological and clinical studies has transformed the once generally discounted subject of endocrine disruptors into an issue of tremendous concern not only within the scientific community but among society as a whole. Following initial evidence from basic research, endocrine disruption in humans has now emerged as a major medical challenge. In this respect, puberty, a crucial developmental stage, has been definitively identified as a key window of vulnerability with regard to endocrine disruptors. Written by leading authorities in the field, Endocrine Disruptors and Puberty offers an engaging and comprehensive overview of this fascinating and rapidly growing problem. An indispensable resource for all clinicians and scientists interested in this challenging endocrinologic topic, Endocrine Disruptors and Puberty is a timely contribution that will help navigate a path toward understanding the problem and developing solutions.
Hormones And Brain Plasticity
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Author : Luis Miguel Garcia-Segura
language : en
Publisher: Oxford University Press
Release Date : 2009-05-05
Hormones And Brain Plasticity written by Luis Miguel Garcia-Segura and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-05 with Medical categories.
The nervous system has a remarkable capacity for self-reorganization, and in this first systematic analysis of the interaction between hormones and brain plasticity, Luis Miguel Garcia-Segura proposes that hormones modulate metaplasticity in the brain. He covers a wide variety of hormones, brain regions, and neuroplastic events, and also provides a new theoretical background with which to interpret the interaction of hormones and brain remodeling throughout the entire life of the organism. Garcia-Segura argues that hormones are indispensable for adequately adapting the endogenous neuroplastic activity of the brain to the incessant modifications in external and internal environments. Their regulation of neuroplastic events in a given moment predetermines new neuroplastic responses that will occur in the future, adapting brain reorganization to changing physiological and behavioral demands throughout the life of the organism. The cross-regulation of brain plasticity and hormones integrates information originated in multiple endocrine glands and body organs with information coming from the external world in conjunction with the previous history of the organism. Multiple hormonal signals act in concert to regulate the generation of morphological and functional changes in neural cells, as well as the replacement of neurons, glial, and endothelial cells in neural networks. Brain remodeling, in turn, is involved in controlling the activity of the endocrine glands and regulating hormonal secretions. This bidirectional adjustment of brain plasticity in response to hormonal inputs, and adjustment of hormonal concentrations in response to neuroplastic events are crucial for maintaining the stability of the inner milieu and for the generation of adequate behavioral responses in anticipation of--and in adaptation to--new social and environmental circumstances and life events, including pathological conditions.
Methods Of Behavior Analysis In Neuroscience
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Author : Jerry J. Buccafusco
language : en
Publisher: CRC Press
Release Date : 2000-08-29
Methods Of Behavior Analysis In Neuroscience written by Jerry J. Buccafusco and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-08-29 with Medical categories.
Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic
Endocrine Disrupting Chemicals
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Author :
language : en
Publisher: Academic Press
Release Date : 2021-08-27
Endocrine Disrupting Chemicals written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-27 with Medical categories.
Advances in Pharmacology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Advances in Pharmacology series Updated release includes the latest information on Endocrine-Disrupting Chemicals
Toxic Cocktail
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Author : Barbara Demeneix
language : en
Publisher: Oxford University Press
Release Date : 2017-01-02
Toxic Cocktail written by Barbara Demeneix and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-02 with Psychology categories.
In today's world, everyone carries a toxic load of dozens of industrially produced chemicals in their bloodstream. Not only do these adversely affect the health of adults and children, but also, and more worryingly, they damage the development of unborn infants. The amniotic fluid of pregnant women has been found to contain a variety of chemicals, such as pesticides, plasticizers, disinfectant products, flame-retardants, surfactants and UV filters, many of which interfere with fetal physiology, especially thyroid hormone action. Thyroid hormone is vital for brain development, particularly for the fetus during pregnancy and for toddlers. In fact, children born to women who lack this thyroid hormone (or who are unwittingly exposed to thyroid-disrupting chemicals) have lower IQs and more neurodevelopmental problems. Evolution of the human brain has involved multiple changes and processes dependent on thyroid hormone. The urgent question thus arises: Is chemical pollution poisoning brain development and reversing evolution's most outstanding achievement: the human brain? And if so, as this book convincingly illuminates, what can be done about it both collectively and individually? Toxic Cocktail provides a clear view of how many environmental chemicals interfere with brain development. As a result, this book looks at how we define and test IQ, the evidence for IQ loss, and how chemical pollution and thyroid hormone disruption can be actors in this process, as well as increasing neurodevelopmental disease risk.