Endorphins And Opiate Antagonists In Psychiatric Research
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Endorphins And Opiate Antagonists In Psychiatric Research
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Author : Nandkumar S. Shah
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Endorphins And Opiate Antagonists In Psychiatric Research written by Nandkumar S. Shah and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Business & Economics categories.
The discovery of new molecules that function in neuronal communication can be viewed as a progression of steps beginning with the identification of the molecular structure, moving to the understanding of the mecha nisms mediating the synaptic action, and to the appraisal of the involve ment of the new molecules in various neuronal mechanisms, and finally reaching the evaluation of this molecule's role in brain function and the consequences that are triggered by its abnormalities. Enkephalins have followed such a pattern, and the present publication expresses the salient points of the last two phases in this succession. Enkephalins were discovered in December 1975; in addition to pain threshold regulation, their participation in other brain functions was soon ascertained. Perhaps, there are multiple recognition sites for multiple molecular forms of endogenous enkephalins; similarly to other transmitter recognition sites, these are coupled with ionic and nucleotide amplifying systems; thus, when activated, they can modify membrane funtion and ionic permeability of membranes. The present publication probes the current status of our knowledge concerning the consequences related to abnormalities in enkephalin storage, release, and synthesis. However, since our basic understanding of enkephalins is incomplete, the views reported should be considered to be in a state of flux.
Endorphins And Opiate Antagonists In Psychiatric Research
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Author : 3Island Press
language : en
Publisher:
Release Date : 1982-08-31
Endorphins And Opiate Antagonists In Psychiatric Research written by 3Island Press and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982-08-31 with categories.
Endorphins In Mental Health Research
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Author : Earl Usdin
language : en
Publisher: Springer
Release Date : 2016-01-14
Endorphins In Mental Health Research written by Earl Usdin and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-14 with Medical categories.
Opiate Receptors And Antagonists
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Author : Reginald Dean
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-03-12
Opiate Receptors And Antagonists written by Reginald Dean and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-12 with Medical categories.
Comprehensive and authoritative, Opioid Receptors and Antagonists: From Bench to Clinic offers neuroscientists, pharmacologists and interested clinicians a unique survey of the extensive and diverse research efforts currently employed with opioid antagonists to develop novel innovative drug therapies. Summarizes the present understanding of the chemistry, pharmacology and molecular biology of opioid receptors and their subtypes Highlights differences and similarities between the opioid pharmacology of animals and human Describes current and potential therapeutic areas for opioid antagonists, including substance abuse, alcohol and ingestive behaviors, behavioral disorders and other medical indications, supported by nonclinical and clinical evidence Focuses on the development of exciting and innovative drug delivery approaches that are being used with opioid antagonists for the above medical indications
Opiate Receptors And Antagonists
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Author : Reginald Dean
language : en
Publisher: Humana Press
Release Date : 2009-05-04
Opiate Receptors And Antagonists written by Reginald Dean and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-04 with Medical categories.
Comprehensive and authoritative, Opioid Receptors and Antagonists: From Bench to Clinic offers neuroscientists, pharmacologists and interested clinicians a unique survey of the extensive and diverse research efforts currently employed with opioid antagonists to develop novel innovative drug therapies. Summarizes the present understanding of the chemistry, pharmacology and molecular biology of opioid receptors and their subtypes Highlights differences and similarities between the opioid pharmacology of animals and human Describes current and potential therapeutic areas for opioid antagonists, including substance abuse, alcohol and ingestive behaviors, behavioral disorders and other medical indications, supported by nonclinical and clinical evidence Focuses on the development of exciting and innovative drug delivery approaches that are being used with opioid antagonists for the above medical indications
Conceptual Issues In Alcoholism And Substance Abuse
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Author : Barry Stimmel
language : en
Publisher: Psychology Press
Release Date : 1984
Conceptual Issues In Alcoholism And Substance Abuse written by Barry Stimmel and has been published by Psychology Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Drug abuse categories.
This timely volume emphasizes the relevance of current, basic research to the clinical management of the substance abuser.
Nida Research Monograph
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Author :
language : en
Publisher:
Release Date : 1976
Nida Research Monograph written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Drug abuse categories.
Cerebrospinal Fluid In Neurology And Psychiatry
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Author : Joseph R. Bianchine
language : en
Publisher: Springer
Release Date : 2013-11-11
Cerebrospinal Fluid In Neurology And Psychiatry written by Joseph R. Bianchine and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
Scientists have speculated as to the nature of cerebrospinal fluid (CSF) - "the third circulation" or "vital spirit" for centuries. Just what is this mysterious bathing solution of the central nervous system? Is it a vehicle of transport for an "animal spirit" directing all our activities, as thought by Galen (Singer, 1956) or but a "modified tap water" (Halliburton, 1917)? With the advent of lumbar puncture, cerebrospinal fluid has become a readily available and important means of studying disease affecting the nervous system. In recent years, many sophisticated tools including com puter guided gas chromatography/mass spectrometry and high performance liquid chromatography have made it possible to identify and quantify many constituents of this fluid. The CSF has an enormous, though largely "untapped", potential in aiding diagnosis and evaluating treatment of many neurological, psychiatric and systemic disorders. As the ependyma is only a diffusional barrier between the CSF and extracellular fluid of the brain for many compounds, changes in the concentration of these compounds in the CSF may reflect disease processes in the brain.
B Endorphin
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Author : Choh Hao Li
language : en
Publisher: Elsevier
Release Date : 2012-12-02
B Endorphin written by Choh Hao Li and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Hormonal Proteins and Peptides: ß-Endorphin, Volume X focuses on the chemistry, biology, and clinical investigations of opioid peptides. This book discusses the chemical approach in isolating a chemical entity from its natural source and investigates its biological activity after it has been determined to be a pure substance. Organized into nine chapters, this volume starts with an overview of the structure–activity relationship of ß-endorphin (ß-EP) by synthetic approach. This text then explores the proteinases involved in the generation of opioid peptides, including ß-EP from ß-lipotropin (ß-LPH). Other chapters review the biosynthesis of ß-EP and consider in detail the opiate receptor. This book discusses as well the anatomy of ß-EP-containing structures in pituitary and brain. The final chapter presents a discussion on the historical aspects of opiate–peptide discoveries, particularly in the field of narcotic antagonists. This book is a valuable resource for chemists, biologists, endocrinologists, physicians, and neurobiologists.
Psychoneuroendocrine Dysfunction
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Author : Nandkumar S. Shah
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Psychoneuroendocrine Dysfunction written by Nandkumar S. Shah and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.
There is no area in medicine that has affected biological psychiatry more pro 15 years in en foundly than the developments that have occurred in the last docrinology and more specifically in neuroendocrinology. In the 1960s, the regulation of endocrine function was considered to rest primarily in the feed back system between the pituitary and the secretions of various target organs. In R. H. Williams' Fourth Edition of the Textbook of Endocrinology published in 1968, the chapter on neuroendocrinology did refer to the median eminence gland with a relatively brief mention of various releasing factors that were the subject of ongoing studies. Only six years later, in the Fifth Edition published in 1974, Seymour Reichlin's chapter on neuroendocrinology listed nine specific hypothalamic releasing factors of which three had already been isolated and purified and thus were referred to as hormones. Most recently in the current Sixth Edition, published in 1981, the chapter on neuroendocrinology contains a detailed description of the physiology of the various hypothalamic releasing factors and hormones, but also significant emphasis is given to the various neurotransmitters that have been shown to regulate the synthesis and release of these important hypothalamic hormones. In addition, there appeared for the first time in this classic textbook a chapter on psychoendocrinology. One may wonder why there is so much interest not only in endocrinology but more recently in psychology and psychiatry about psychoneuroendocrine It has been known for some time function. Several reasons may be suggested.