Engineering Of Microbial Biosynthetic Pathways
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Engineering Of Microbial Biosynthetic Pathways
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Author : Vijai Singh
language : en
Publisher: Springer Nature
Release Date : 2020-07-16
Engineering Of Microbial Biosynthetic Pathways written by Vijai Singh and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-16 with Medical categories.
This book provides a comprehensive overview of the basic and advanced metabolic engineering technologies used to generate natural metabolites and industrially important biomolecules. Metabolic engineering has the potential to produce large quantities of valuable biomolecules in a renewable and sustainable manner by extending or modifying biosynthetic pathways in a wide range of organisms. It has been successfully used to produce chemicals, drugs, enzymes, amino acids, antibiotics, biofuels, and industrially important pharmaceuticals. The book comprehensively reviews the various metabolites detection, extraction and biosensors and the metabolic engineering of microbial strains for the production of industrially useful enzymes, proteins, organic acids, vitamins and antibiotics, therapeutics, chemicals, and biofuels. It also discusses various genetic engineering and synthetic biology tools for metabolic engineering. In closing, the book discusses ethical, patenting and regulatory issues in the metabolic engineering of microbes. This book is a valuable source not only for beginners in metabolic engineering, but also students, researchers, biotechnology and metabolic engineering based company.
Amino Acid Biosynthesis Pathways Regulation And Metabolic Engineering
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Author : Volker F. Wendisch
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-03-24
Amino Acid Biosynthesis Pathways Regulation And Metabolic Engineering written by Volker F. Wendisch and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-24 with Science categories.
This book presents the current knowledge of fundamental as well as applied microbiology of amino acids. Coverage details the amino acid biosynthetic pathways, their genetic and biochemical regulation, transport of amino acids and genomics of producing microorganisms. The book also examines the metabolic engineering of microorganisms for the biotechnological production of amino acids for use as pharmaceuticals and as food and feed additives.
The Science And Applications Of Synthetic And Systems Biology
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2011-12-30
The Science And Applications Of Synthetic And Systems Biology written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-30 with Science categories.
Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.
Engineering Biology For Microbial Biosynthesis Of Plant Derived Bioactive Compounds
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Author : Yongjun Wei
language : en
Publisher: Elsevier
Release Date : 2024-03-01
Engineering Biology For Microbial Biosynthesis Of Plant Derived Bioactive Compounds written by Yongjun Wei and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-01 with Science categories.
Many plant-derived bioactive compounds are the foundation effective drugs to cure diseases. Usually, the bioactive compounds in plant biomass are low, and the extraction of bioactive compounds from plants is not eco-friendly, which limits their application in drugs and other industries. With the development of synthetic biology and green biomanufacturing, the biosynthesis of complex bioactive compounds is possible. However, the engineering fundamentals for microbial biosynthetic of plant-derived bioactive compounds is vast. Engineering biology for microbial biosynthesis of plant-derived bioactive compounds summarizes the engineering fundamental biotechnologies for microbial production of plant-derived bioactive compounds, allowing this content to be easily accessed. Coverage includes summaries of key achievements, identification of challenges, current approaches, tips and tricks, and helpful insights into critical bottlenecks. With a comprehensive coverage of the field, Engineering biology for microbial biosynthesis of plant-derived bioactive compounds is of great interest to undergraduate and graduate students, scientists, researchers as well as engineers who work on the microbial production of plant-derived bioactive compounds. - Provides valuable information for engineers, scientists, and industrial researchers who want to obtain microbial strains with the ability of plant-derived bioactive compound production - Guides microbial production of plant-derived bioactive compounds at the laboratory and industrial levels - Ideal resource for anyone who works on the microbial production of plant-derived bioactive compounds
Systems Metabolic Engineering
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Author : Christoph Wittmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-06-15
Systems Metabolic Engineering written by Christoph Wittmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-15 with Science categories.
Systems Metabolic Engineering is changing the way microbial cell factories are designed and optimized for industrial production. Integrating systems biology and biotechnology with new concepts from synthetic biology enables the global analysis and engineering of microorganisms and bioprocesses at super efficiency and versatility otherwise not accessible. Without doubt, systems metabolic engineering is a major driver towards bio-based production of chemicals, materials and fuels from renewables and thus one of the core technologies of global green growth. In this book, Christoph Wittmann and Sang-Yup Lee have assembled the world leaders on systems metabolic engineering and cover the full story – from genomes and networks via discovery and design to industrial implementation practises. This book is a comprehensive resource for students and researchers from academia and industry interested in systems metabolic engineering. It provides us with the fundaments to targeted engineering of microbial cells for sustainable bio-production and stimulates those who are interested to enter this exiting research field.
Microbial Production Of L Amino Acids
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Author : Robert Faurie
language : en
Publisher: Springer
Release Date : 2003-07-01
Microbial Production Of L Amino Acids written by Robert Faurie and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-07-01 with Science categories.
This volume deals with "Microbial Production of L-Amino Acids" and presents five comprehensive, expert and actual review articles on the modern production of Amino Acids by application of biotechnologically optimized microorganisms. This includes not only the modern techniques of enzyme, metabolic and transport engineering but also sophisticated analytical methods like metabolic flux analysis and subsequent pathway modeling. A general review about industrial processes of Amino Acid production provides a comprehensive overview about recent strain development as well as fermentation technologies. It was our special interest to focus the other articles on the most important and best selling amino acids on the world market i.e. L-Glutamate, L-Lysine and L-Threonine. The authors of this special volume have contributed significantly to the progress of Amino Acid biotechnology in the last decades and earn our special gratitude and admiration for their expert review articles.
Industrial Biotechnology
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Author : Christoph Wittmann
language : en
Publisher: John Wiley & Sons
Release Date : 2017-04-10
Industrial Biotechnology written by Christoph Wittmann and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-10 with Science categories.
The latest volume in the Advanced Biotechnology series provides an overview of the main production hosts and platform organisms used today as well as promising future cell factories in a two volume book. Alongside describing tools for genetic and metabolic engineering for strain improvement, the authors also impart topical information on computational tools, safety aspects and industrial-scale production. Following an introduction to general concepts, historical developments and future technologies, the text goes on to cover multi-purpose bacterial cell factories, including those organisms that exploit anaerobic biosynthetic power. Further chapters deal with microbes used for the production of high-value natural compounds and those obtained from alternative raw material sources, concluding with eukaryotic workhorses.
Metabolic Engineering
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Author : Sang Yup Lee
language : en
Publisher: CRC Press
Release Date : 1999-09-29
Metabolic Engineering written by Sang Yup Lee and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-09-29 with Science categories.
This unique reference/text presents the basic theory and practical applications of metabolic engineering (ME). It offers systematic analysis of complex metabolic pathways and ways of employing recombinant DNA techniques to alter cell behavior, metabolic patterns, and product formation. Treating ME as a distinct subfield of genetic engineering, the book demonstrates new means of enabling cells to produce valuable proteins, polypeptides, and primary and secondary metabolites. Written by more than 35 leading international experts in the field, this book discusses metabolic engineering in plant and mammalian cells, bacteria, and yeasts and assesses metabolic engineering applications in agriculture, pharmaceuticals, and environmental systems. It illuminates the potential of the "cell factory" model for production of chemicals and therapeutics and examines methods for developing new antiviral and antibacterial molecules and effective gene and somatic-cell therapies. Metabolic Engineering also addresses the use of metabolic flux analysis, metabolic control analysis, and online metabolic flux analysis.
Sustainable Production Innovations
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Author : Alok Kumar Patel
language : en
Publisher: John Wiley & Sons
Release Date : 2023-08-29
Sustainable Production Innovations written by Alok Kumar Patel and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-29 with Science categories.
SUSTAINABLE PRODUCTION INNOVATIONS Presenting the latest technologies and practices in this ever-changing field, this groundbreaking new volume covers the gambit for providing solutions and practical applications of smart and efficient energy systems. The global and climate changes we are witnessing are primarily driven by factors such as rising population, economic growth, and industrialization. These changes have led to an increase in atmospheric CO2, pollution, deforestation, water scarcity, and hunger, among other pressing issues. To ensure a green and sustainable future, it is crucial to harness renewable resources for the production of fuels, chemicals, and materials. The book, Sustainable Production Innovations, addresses several bioprocesses that are integral to our daily lives, tackling important topics such as biofuel production, energy and food security, and wastewater management. The commercial interest in biotechnological processes has grown significantly due to their ability to utilize biocatalysts such as enzymes, bacteria, plant cells, or animal cells in bioreactors for the production of medications, health supplements, foods, biofuels, and chemicals. Switching to bioproducts offers key benefits such as the sustainability of third-generation biofuels, CO2 sequestration, effective waste utilization, and meeting the increasing demand for clean water. The book explores various procedures used in biomass biorefineries and bioprocessing for the production of biofuels, biobased chemicals, and bioproducts. It also delves into advancements in utilizing oleaginous microorganisms for biofuels and nutraceuticals, biological wastewater treatment, and microplastic detection techniques in water. Additionally, the book covers topics such as biolubricant technologies, bioprocessing of agricultural and forest waste, biotechnological approaches in the cosmetic industry, and large-scale applications of nanomaterials for water treatment. Authored by experts from leading biotechnology research groups around the world, the book comprises 13 chapters featuring the latest research in each subject. It is a valuable resource for scholars in chemical engineering, applied microbiology, biotechnology, agricultural biotechnology, environmental biotechnology, and related fields, offering new insights into the sustainable use of renewable energy and biochemicals. Professionals, including biochemical engineers, phycologists, bioprocess engineers, chemical engineers, scientists, and researchers in the water, food, pharmaceutical, and renewable energy industries will find this book beneficial. Likewise, students and faculty in the chemical engineering and energy departments will gain valuable knowledge from its contents.
New And Future Developments In Microbial Biotechnology And Bioengineering
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Author : Vijai G. Gupta
language : en
Publisher: Elsevier
Release Date : 2019-06-14
New And Future Developments In Microbial Biotechnology And Bioengineering written by Vijai G. Gupta and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-14 with Medical categories.
New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Secondary Metabolites Biochemistry and Applications examines the areas of biotechnology and chemical engineering, covering aspects of plants, bacteria and machines, and using microbes as factories. The book is aimed at undergraduates, post-graduates and researchers studying microbial secondary metabolites, and is an invaluable reference source for biochemical engineers working in biotechnology, manipulating microbes, and developing new uses for bacteria and fungi. The applications of secondary metabolites in biotechnology, pharmaceuticals, diagnostics and medical device development are also extensively covered. The book integrates the aforementioned frontline branches into an interdisciplinary research work to satisfy those working in biotechnology, chemical engineering, alternative fuel development, diagnostics and pharmaceuticals. Chapters related to important research work on applications of microbial secondary metabolites are written by specialists in the various disciplines from the international community. - Compiles the latest developments in the area of microbial secondary metabolites - Authored by the top international researchers in this area - Includes information related to nearly all areas of a microbial secondary metabolites system