Engineering Synthetic Metabolons From Metabolic Modelling To Rational Design Of Biosynthetic Devices
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Engineering Synthetic Metabolons From Metabolic Modelling To Rational Design Of Biosynthetic Devices
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Author : Lars M. Voll
language : en
Publisher: Frontiers Media SA
Release Date : 2016-07-19
Engineering Synthetic Metabolons From Metabolic Modelling To Rational Design Of Biosynthetic Devices written by Lars M. Voll and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-19 with Biotechnology categories.
The discipline of Synthetic Biology has recently emerged at the interface of biology and engineering. The definition of Synthetic Biology has been dynamic over time ever since, which exemplifies that the field is rapidly moving and comprises a broad range of research areas. In the frame of this Research Topic, we focus on Synthetic Biology approaches that aim at rearranging biological parts/ entities in order to generate novel biochemical functions with inherent metabolic activity. This Research Topic encompasses Pathway Engineering in living systems as well as the in vitro assembly of biomolecules into nano- and microscale bioreactors. Both, the engineering of metabolic pathways in vivo, as well as the conceptualization of bioreactors in vitro, require rational design of assembled synthetic pathways and depend on careful selection of individual biological functions and their optimization. Mathematical modelling has proven to be a powerful tool in predicting metabolic flux in living and artificial systems, although modelling approaches have to cope with a limitation in experimentally verified, reliable input variables. This Research Topic puts special emphasis on the vital role of modelling approaches for Synthetic Biology, i.e. the predictive power of mathematical simulations for (i) the manipulation of existing pathways and (ii) the establishment of novel pathways in vivo as well as (iii) the translation of model predictions into the design of synthetic assemblies.
Engineering Synthetic Metabolons From Metabolic Modelling To Rational Design Of Biosynthetic Devices
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Author :
language : en
Publisher:
Release Date : 2016
Engineering Synthetic Metabolons From Metabolic Modelling To Rational Design Of Biosynthetic Devices written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.
The discipline of Synthetic Biology has recently emerged at the interface of biology and engineering. The definition of Synthetic Biology has been dynamic over time ever since, which exemplifies that the field is rapidly moving and comprises a broad range of research areas. In the frame of this Research Topic, we focus on Synthetic Biology approaches that aim at rearranging biological parts/ entities in order to generate novel biochemical functions with inherent metabolic activity. This Research Topic encompasses Pathway Engineering in living systems as well as the in vitro assembly of biomolecules into nano- and microscale bioreactors. Both, the engineering of metabolic pathways in vivo, as well as the conceptualization of bioreactors in vitro, require rational design of assembled synthetic pathways and depend on careful selection of individual biological functions and their optimization. Mathematical modelling has proven to be a powerful tool in predicting metabolic flux in living and artificial systems, although modelling approaches have to cope with a limitation in experimentally verified, reliable input variables. This Research Topic puts special emphasis on the vital role of modelling approaches for Synthetic Biology, i.e. the predictive power of mathematical simulations for (i) the manipulation of existing pathways and (ii) the establishment of novel pathways in vivo as well as (iii) the translation of model predictions into the design of synthetic assemblies.
Biotechnology Of Isoprenoids
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Author : Jens Schrader
language : en
Publisher: Springer
Release Date : 2015-05-19
Biotechnology Of Isoprenoids written by Jens Schrader and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-19 with Science categories.
This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.
Preparing For Future Products Of Biotechnology
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2017-07-28
Preparing For Future Products Of Biotechnology written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-28 with Science categories.
Between 1973 and 2016, the ways to manipulate DNA to endow new characteristics in an organism (that is, biotechnology) have advanced, enabling the development of products that were not previously possible. What will the likely future products of biotechnology be over the next 5â€"10 years? What scientific capabilities, tools, and/or expertise may be needed by the regulatory agencies to ensure they make efficient and sound evaluations of the likely future products of biotechnology? Preparing for Future Products of Biotechnology analyzes the future landscape of biotechnology products and seeks to inform forthcoming policy making. This report identifies potential new risks and frameworks for risk assessment and areas in which the risks or lack of risks relating to the products of biotechnology are well understood.
Functional Metabolism
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Author : Kenneth B. Storey
language : en
Publisher: John Wiley & Sons
Release Date : 2005-02-25
Functional Metabolism written by Kenneth B. Storey and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-02-25 with Science categories.
Functional Metabolism of Cells is the first comprehensive survey of metabolism, offering an in-depth examination of metabolism and regulation of carbohydrates, lipids, and amino acids. It provides a basic background on metabolic regulation and adaptation as well as the chemical logic of metabolism, and covers the interrelationship of metabolism to life processes of the whole organism. The book lays out a structured approach to the metabolic basis of disease, including discussion of the normal pathways of metabolism, altered pathways leading to disease, and use of molecular genetics in diagnosis and treatment of disease. It also takes a unique comparative approach in which human metabolism is a reference for metabolism in microorganisms and plant design, and presents novel coverage of development and aging, and human health and animal adaptation. The final chapter reviews the past and future promise of new genetic approaches to treatment and bioinformatics. This, the most exhaustive treatment of metabolism currently available, is a useful text for advanced undergraduates and graduates in biochemistry, cell/molecular biology, and biomedicine, as well as biochemistry instructors and investigators in related fields.
Methane Biocatalysis Paving The Way To Sustainability
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Author : Marina G. Kalyuzhnaya
language : en
Publisher: Springer
Release Date : 2018-06-20
Methane Biocatalysis Paving The Way To Sustainability written by Marina G. Kalyuzhnaya and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-20 with Science categories.
This book provides in-depth insights into the most recent developments in different areas of microbial methane and methanol utilization, including novel fundamental discoveries in genomics and physiology, innovative strategies for metabolic engineering and new synthetic approaches for generation of feedstocks, chemicals and fuels from methane, and finally economics and the implementation of industrial biocatalysis using methane consuming bacteria. Methane, as natural gas or biogas, penetrates every area of human activity, from households to large industries and is often promoted as the cleanest fuel. However, one should not forget that this bundle of energy, carbon, and hydrogen comes with an exceptionally large environmental footprint. To meet goals of long-term sustainability and human well-being, all areas of energy, chemicals, agriculture, waste-management industries must go beyond short-term economic considerations and target both large and small methane emissions. The search for new environment-friendly approaches for methane capture and valorization is an ongoing journey. While it is not yet apparent which innovation might represent the best solution, it is evident that methane biocatalysis is one of the most promising paths. Microbes are gatekeepers of fugitive methane in Nature. Methane-consuming microbes are typically small in number but exceptionally big in their impact on the natural carbon cycle. They control and often completely eliminate methane emission from a variety of biological and geothermal sources. The tremendous potential of these microbial systems, is only now being implemented in human-made systems. The book addresses professors, researchers and graduate students from both academia and industry working in microbial biotechnology, molecular biology and chemical engineering.
Medicinal Plant Biotechnology
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Author : Rajesh Arora
language : en
Publisher: CABI
Release Date : 2010
Medicinal Plant Biotechnology written by Rajesh Arora and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Science categories.
Printbegrænsninger: Der kan printes 10 sider ad gangen og max. 40 sider pr. session
Plant Metabolomics
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Author : Kazuki Saito
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-06-29
Plant Metabolomics written by Kazuki Saito and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-29 with Science categories.
Metabolomics – which deals with all metabolites of an organism – is a rapidly-emerging sector of post-genome research fields. It plays significant roles in a variety of fields from medicine to agriculture and holds a fundamental position in functional genomics studies and their application in plant biotechnology. This volume comprehensively covers plant metabolomics for the first time. The chapters offer cutting-edge information on analytical technology, bioinformatics and applications. They were all written by leading researchers who have been directly involved in plant metabolomics research throughout the world. Up-to-date information and future developments are described, thereby producing a volume which is a landmark of plant metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all plant science fields.
Metabolic Engineering Of Plant Secondary Metabolism
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Author : R. Verpoorte
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Metabolic Engineering Of Plant Secondary Metabolism written by R. Verpoorte and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
Plant secondary metabolism is an economically important source of fine chemicals, such as drugs, insecticides, dyes, flavours, and fragrances. Moreover, important traits of plants such as taste, flavour, smell, colour, or resistance against pests and diseases are also related to secondary metabolites. The genetic modification of plants is feasible nowadays. What does the possibility of engineering plant secondary metabolite pathways mean? In this book, firstly a general introduction is given on plant secondary metabolism, followed by an overview of the possible approaches that could be used to alter secondary metabolite pathways. In a series of chapters from various authorities in the field, an overview is given of the state of the art for important groups of secondary metabolites. No books have been published on this topic so far. This book will thus be a unique source of information for all those involved with plants as chemical factories of fine chemicals and those involved with the quality of food and ornamental plants. It will be useful in teaching graduate courses in the field of metabolic engineering in plants.
Bioorganic Mechanisms
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Author : Thomas C. Bruice
language : en
Publisher:
Release Date : 1966
Bioorganic Mechanisms written by Thomas C. Bruice and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1966 with Biochemistry categories.