Engineering The Human Germline
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Engineering The Human Germline
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Author : Gregory Stock
language : en
Publisher: Oxford University Press
Release Date : 2000-02-03
Engineering The Human Germline written by Gregory Stock and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-02-03 with Medical categories.
This book explores the many prospects, challenges and ethical questions that surround the engineering of our reproductive cells. It is an accessible, three-part examination, moving from focused, realistic assessments of the promise and problems for this advancing technology to a section of short essays on the implications of our technological ability. Also included is a panel discussion in which leading scientists, ethicists, and public policy workers give voice to their thoughts and concerns regarding our impending genetic technologies. Many world leaders in these fields, including Leroy Hood, French Anderson, Mario Capecchi, Daniel Koshland, Michael Rose, Lee Silver, and James Watson, have contributed to this volume, providing the essential elements of the debate over germline engineering. If you have ever pondered the question: "Would I be willing to genetically alter my own child-to-be, given a safe, reliable technology, offering a tempting possibility?", this book will be an indispensable guide.
The Science And Ethics Of Engineering The Human Germ Line
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Author : Jon W. Gordon
language : en
Publisher: John Wiley & Sons
Release Date : 2003-09-24
The Science And Ethics Of Engineering The Human Germ Line written by Jon W. Gordon and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-24 with Science categories.
With implications that go to the core of what it means to be human, the issues raised by genetic manipulation-especially cloning-have sparked a passionate debate among governmental, religious, and scientific quarters, as well as the media and the general public. Keeping to the actual science rather than speculation is of the utmost importance for an enlightened approach to this weighty discussion. In clear, lively prose, The Science and Ethics of Engineering the Human Germ Line: Mendel's Maze provides an authoritative treatment of the principles of science and bioethics that bear upon such technologies as germ-line insertion and cloning. It offers a realistic assessment of possible applications, limitations, and new developments likely to arise in these areas. Written by a top physician-investigator, this book progresses from the basics of building a living organism from inanimate parts through to recombinant DNA technology, assisted reproductive technologies, and gene transfer and germ-line engineering. Ethical considerations are woven into this material throughout, while a special section covers the intellectual role played by various social biases. As genetic and reproductive technologies spread from the laboratory to the clinic-and society takes further notice-students and practitioners of biology and medicine, as well as the interested general reader, will find The Science and Ethics of Engineering the Human Germ Line: Mendel's Maze to be an essential and accessible guide to these important subjects.
Human Germline Modification And The Right To Science
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Author : Andrea Boggio
language : en
Publisher: Cambridge University Press
Release Date : 2020-01-09
Human Germline Modification And The Right To Science written by Andrea Boggio and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-09 with Law categories.
A survey of the regulation of human germline genome modification in eighteen countries and the emerging international standards.
Heritable Human Genome Editing
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Author : The Royal Society
language : en
Publisher: National Academies Press
Release Date : 2021-01-16
Heritable Human Genome Editing written by The Royal Society and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-16 with Medical categories.
Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.
Human Genome Editing
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2017-08-13
Human Genome Editing written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-13 with Medical categories.
Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.
Redesigning Humans
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Author : Gregory Stock
language : en
Publisher: Houghton Mifflin Harcourt
Release Date : 2003
Redesigning Humans written by Gregory Stock and has been published by Houghton Mifflin Harcourt this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Medical categories.
Writing for the lay reader, Stock, the director of the Program on Medicine, Technology, and Society at the School of Public Health at UCLA, discusses the science, potential impact, and many controversies surrounding the development of germline engineering, which involves selectively altering human g
Design And Destiny
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Author : Ronald Cole-Turner
language : en
Publisher: MIT Press
Release Date : 2008
Design And Destiny written by Ronald Cole-Turner and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.
Scholars discuss the genetic modification of embryonic cells from the viewpoints of traditional Jewish and Christian teaching, considering both the possible therapeutic benefits of this technology and moral concerns about its implementation. We are approaching the day when advances in biotechnology will allow parents to "design" a baby with the traits they want. The continuing debate over the possibilities of genetic engineering has been spirited, but so far largely confined to the realms of bioethics and public policy. Design and Destiny approaches the question in religious terms, discussing human germline modification (the genetic modification of the embryonic cells that become the eggs or sperm of a developing organism) from the viewpoints of traditional Christian and Jewish teaching. The contributors, leading religious scholars and writers, call our attention not to technology but to humanity, reflecting upon the meaning and destiny of human life in a technological age. Many of these scholars argue that religious teaching can support human germline modification implemented for therapeutic reasons, although they offer certain moral conditions that must be met. The essays offer a surprising variety of opinions, including a discussion of Judaism's traditional presumption in favor of medicine, an argument that Catholic doctrine could accept germline modification if it is therapeutic for the embryo, an argument implying that "traditional" Christian teaching permits germline modification whether for therapy or enhancement, and a "classical" Protestant view that germline modification should be categorically opposed. Contributors Lisa Sowle Cahill, Nigel M. de S. Cameron, Ronald Cole-Turner, Amy Michelle DeBaets, Celia Deane-Drummond, Elliot Dorff, H. Tristram Engelhardt, Jr., Thomas A. Shannon, James J. Walter
Human Genome Editing
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2017-07-13
Human Genome Editing written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-13 with Medical categories.
Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.
The Human Gene Editing Debate
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Author : John H. Evans
language : en
Publisher: Oxford University Press
Release Date : 2020-08-19
The Human Gene Editing Debate written by John H. Evans and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-19 with Science categories.
In 2018 the first genetically modified babies were reportedly born in China, made possible by the invention of CRISPR technology in 2012. This controversial advancement overturned the pre-existing moral consensus, which had held for over fifty years before: while gene editing an adult person was morally acceptable, modifying babies, and thus subsequent generations, crossed a significant moral line. If this line is passed over, scientists will be left without an agreed-upon ethical limit. What do we do now? John H. Evans here provides a meta-level guide to how these debates move forward and their significance to society. He explains how the bioethical debate has long been characterized as a slippery slope, with consensually ethical use at the top, nightmarish dystopia at the bottom, and specific agreed-upon limits in between, which draw the lines between the ethical and the unethical. Evans frames his analysis around these limits, or barriers. Historically they have existed to guide scientists and to prevent the debate from slipping down the metaphorical slope into unacceptable eugenicist possibilities, such as in Aldous Huxley's novel Brave New World or the movie Gattaca. Evans examines the history of how barriers were placed, then fell, then replaced by new ones, and discusses how these insights inform where the debate may head. He evaluates other proposed barriers relevant to where we are now, projects that most of the barriers suggested by scientists and bioethicists will not hold, and cautiously identifies a few that could serve as the moral boundary for the next generation. At a critical time in this new era of intervention in the human genome, The Human Gene Editing Debate provides a necessary, comprehensive analysis of the conversation's direction, past, present, and future.
The Ethics Of Genetic Engineering
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Author : Roberta M. Berry
language : en
Publisher: Routledge
Release Date : 2013-05-13
The Ethics Of Genetic Engineering written by Roberta M. Berry and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-13 with Medical categories.
Human genetic engineering may soon be possible. The gathering debate about this prospect already threatens to become mired in irresolvable disagreement. After surveying the scientific and technological developments that have brought us to this pass, The Ethics of Genetic Engineering focuses on the ethical and policy debate, noting the deep divide that separates proponents and opponents. The book locates the source of this divide in differing framing assumptions: reductionist pluralist on one side, holist communitarian on the other. The book argues that we must bridge this divide, drawing on the resources from both encampments, if we are to understand and cope with the distinctive problems posed by genetic engineering. These problems, termed "fractious problems," are novel, complex, ethically fraught, unavoidably of public concern, and unavoidably divisive. Berry examines three prominent ethical and political theories – utilitarianism, Kantianism, and virtue ethics – to consider their competency in bridging the divide and addressing these fractious problems. The book concludes that virtue ethics can best guide parental decision making and that a new policymaking approach sketched here, a "navigational approach," can best guide policymaking. These approaches enable us to gain a rich understanding of the problems posed and to craft resolutions adequate to their challenges.