Enzyme Inhibitor From Marine Organisms
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Enzyme Inhibitor From Marine Organisms
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Author : Dirk Tischler
language : en
Publisher: MDPI
Release Date : 2020-12-15
Enzyme Inhibitor From Marine Organisms written by Dirk Tischler and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-15 with Science categories.
Marine habitats are promising sources to identify novel organisms and compounds. A total of 70% of the planet’s surface is covered by ocean, and little is known about the biosphere within these habitats. In the last few years, numerous novel bioactive compounds or secondary metabolites from marine environments have been described. This is, and will be, a promising source of candidate compounds in pharma research and chemical biology. In recent years, a number of novel techniques have been introduced to the field and it has become easier to actually (bio-)prospect compounds such as enzyme inhibitors. Those novel compounds then need to be characterized and evaluated in comparison to well-known representatives. This Special Issue focuses on the description of novel enzyme inhibitors of marine origin, including bioprospecting, omic approaches, and structural and mechanistic aspects.
Enzyme Inhibitor From Marine Organisms
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Author : Dirk Tischler
language : en
Publisher:
Release Date : 2020
Enzyme Inhibitor From Marine Organisms written by Dirk Tischler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
Marine habitats are promising sources to identify novel organisms and compounds. A total of 70% of the planet's surface is covered by ocean, and little is known about the biosphere within these habitats. In the last few years, numerous novel bioactive compounds or secondary metabolites from marine environments have been described. This is, and will be, a promising source of candidate compounds in pharma research and chemical biology. In recent years, a number of novel techniques have been introduced to the field and it has become easier to actually (bio-)prospect compounds such as enzyme inhibitors. Those novel compounds then need to be characterized and evaluated in comparison to well-known representatives. This Special Issue focuses on the description of novel enzyme inhibitors of marine origin, including bioprospecting, omic approaches, and structural and mechanistic aspects.
Marine Biomolecules
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Author : Antonio Trincone
language : en
Publisher: Frontiers Media SA
Release Date : 2015-10-02
Marine Biomolecules written by Antonio Trincone and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-02 with Biotechnology categories.
Oceans include the greatest extremes of pressure, temperature and light, and habitats can range from tropical waters to ocean trenches, several kilometers below sea level at high pressure. With its 70% of the surface of our planet marine ecosystem still remains largely unexplored, understudied and underexploited in comparison with terrestrial ecosystems, organisms and bioprocesses. The biological adaptation of marine organisms to a wide range of environmental conditions in the specific environment (temperature, salinity, tides, pressure, radiation, light, etc.) has made them an enormous reservoir of interesting biological material for both basic research and biotechnological improvements. As a consequence marine ecosystem is valued as a source of enzymes and other biomolecules exhibiting new functions and activities to fulfill human needs. Indeed, in recent years it has been recognised as an untapped source of novel enzymes and metabolites even though, with regard to the assignment of precise biological functions to genes, proteins and enzymes, it is still considered as the least developed. Using metagenomics to recover genetic material directly from environmental samples, this biogenetic diversification can be accessed but despite the contributions from metagenomic technologies the new field requires major improvements. A few words on the complexity of marine environments should be added here. This complexity ranges from symbiotic relationships to biology and chemistry of defence mechanisms and from chemoecology of marine invasions up to the strategies found in prokaryotes to adapt to extreme environments. The interdisciplinary study of this complexity will enable researchers to find an arsenal of enzymes and pathways greatly demanded in biotechnological applications. As far as marine enzymes are concerned they may carry novel chemical and stereochemical properties, thus biocatalytically oriented studies (testing of suitable substrates, appropriate checking of reaction conditions, study of stereochemical asset of catalysis) should be performed to appropriately reveal this “chemical biodiversity” which increases interest for these enzymes. Among other biomolecules, polysaccharides are the most abundant renewable biomaterial found on land and in oceans. Their molecular diversity is very interesting; except polysaccharides used traditionally in food and non-food industries, the structure and the functionality of most of them are unknown and unexplored. Brown seaweeds synthesize unique bioactive polysaccharides: laminarans, alginic acids and fucoidans. A wide range of biological activities (anticoagulant, antitumor, antiviral, anti-inflammation, etc.) have been attributed to fucoidans and their role with respect to structure-activity relationship is still under debate. In this Research Topic, we wish to centralize and review contributions, idea and comments related to the issues above. In particular results of enzymatic bioprospecting in gross marine environment will be acknowledged along with research for structural characterization and biological function of biomolecules such as marine polysaccharides and all kind of research related to the complexity of bioprocesses in marine environments. Inter- and multi-disciplinary approach to this field is favoured in this Research Topic and could greatly be facilitated by the web and open access nature as well.
Marine Enzymes Biotechnology Production And Industrial Applications Part Ii Marine Organisms Producing Enzymes
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Author :
language : en
Publisher: Academic Press
Release Date : 2016-10-18
Marine Enzymes Biotechnology Production And Industrial Applications Part Ii Marine Organisms Producing Enzymes written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-18 with Science categories.
Marine Enzymes Biotechnology: Production and Industrial Applications, Part II - Marine Organisms Producing Enzymes provides a huge treasure trove of information on marine organisms. Nowadays, marine organisms are good candidates for enzymes production and have been recognized as a rich source of biological molecules that are of potential interest to various industries. Marine enzymes such as amylases, carboxymethylcellulases, proteases, chitinases, keratinases, xylanases, agarases, lipases, peroxidase and tyrosinases are widely used in the industry for the manufacture of pharmaceuticals, foods, beverages, and confectioneries, as well as in textile and leather processing, and in waste water treatment. The majority of the enzymes used in the industry are of microbial origin because microbial enzymes are relatively more stable than the corresponding enzymes derived from plants and animals. Focuses on the isolation, characterization, and industrial application of marine enzymes Provides current trends and development of industrial important marine enzymes, including amylases, carboxymethylcellulases, proteases, chitinases, keratinases, xylanases, agarases, lipases, peroxidase, and tyrosinases Presents insights into current trends and approaches for marine enzymes
Marine Enzymes Biotechnology Production And Industrial Applications Part Ii Marine Organisms Producing Enzymes
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Author :
language : en
Publisher: Academic Press
Release Date : 2016-11-11
Marine Enzymes Biotechnology Production And Industrial Applications Part Ii Marine Organisms Producing Enzymes written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-11 with Technology & Engineering categories.
Marine Enzymes Biotechnology: Production and Industrial Applications, Part II - Marine Organisms Producing Enzymes provides a huge treasure trove of information on marine organisms. Nowadays, marine organisms are good candidates for enzymes production and have been recognized as a rich source of biological molecules that are of potential interest to various industries. Marine enzymes such as amylases, carboxymethylcellulases, proteases, chitinases, keratinases, xylanases, agarases, lipases, peroxidase and tyrosinases are widely used in the industry for the manufacture of pharmaceuticals, foods, beverages, and confectioneries, as well as in textile and leather processing, and in waste water treatment. The majority of the enzymes used in the industry are of microbial origin because microbial enzymes are relatively more stable than the corresponding enzymes derived from plants and animals. Focuses on the isolation, characterization, and industrial application of marine enzymes Provides current trends and development of industrial important marine enzymes, including amylases, carboxymethylcellulases, proteases, chitinases, keratinases, xylanases, agarases, lipases, peroxidase, and tyrosinases Presents insights into current trends and approaches for marine enzymes
Marine Microorganisms
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Author : Leo M.L. Nollet
language : en
Publisher: CRC Press
Release Date : 2016-09-19
Marine Microorganisms written by Leo M.L. Nollet and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-19 with Technology & Engineering categories.
The marine environment covers 70% of the earth’s surface and accounts for 98% of the potentially habitable space. The bioactives from marine microorganisms include antibiotic compounds, polysaccharides, inhibitors, enzymes, peptides, and pigments. These are used in various fields of biology that range from nutraceuticals to cosmeceuticals. Recent scientific investigations have revealed that marine microbial compounds exhibit various beneficial biological effects, such as anti-inflammatory, anti-cancer, anti-HIV, anti-hypertensive, and anti-diabetic. Marine Microorganisms: Extraction and Analysis of Bioactive Compounds sheds light on the extraction, clean-up, and detection methods of major compounds from marine organisms. The book includes information on the different classes of marine microorganisms and the different bioactives that can be extracted from bacteria, fungi and microalgae. Divided into 7 chapters, the book covers bioactive marine natural products, such as marine microbes, seaweeds, and marine sponges as potential sources of drug discovery, and focuses on analysis methods of the biocomponents from marine microorganisms. A useful reference tool for researchers and students, this book provides current knowledge about isolation and analysis methods of the bioactives and provides insight into the various bioactives of marine microbes toward nutraceutical and pharmaceutical development.
Marine Niche Applications In Pharmaceutical Sciences
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Author : Neelam M Nathani
language : en
Publisher: Springer Nature
Release Date : 2020-11-09
Marine Niche Applications In Pharmaceutical Sciences written by Neelam M Nathani and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-09 with Medical categories.
This book offers a comprehensive study of biological molecules acquired from marine organisms, which have been exploited for drug discovery with the aim to treat human diseases. Biomolecules have potential impacts on a diverse range of fields, including medical and pharmaceutical science, industrial science, biotechnology, basic research, molecular science, environmental science and climate change, etc. To understand and effectively apply medicinally important biomolecules, multidisciplinary approaches are called for. The ocean remains a rich biological resource, and the vast untapped potential of novel molecules from marine bio-resources has caught the interest of more and more researchers. These novel biological compounds have never been found in terrestrial or other ecosystems, but only in this rich niche. Advances in sampling techniques and technologies, along with increased funding for research and nature conservation, have now encouraged scientists to look deeper in the waters. Aquaculture supports both tremendous seafood production and the bulk production of marine-derived drugs. Furthermore, molecular methods are now being extensively employed to explore the untapped marine microbial diversity. With the help of molecular and biotech tools, the ability of marine organisms to produce new biosynthetic drugs can be greatly enhanced. This book provides an extensive compilation of the latest information on marine resources and their undisputedly vital role in the treatment of diverse ailments.
Nutraceuticals From Microbes Of Marine Sources
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Author : Charu Gupta
language : en
Publisher:
Release Date : 2019
Nutraceuticals From Microbes Of Marine Sources written by Charu Gupta and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Science categories.
Therapeutic compounds can be derived from various natural sources like plants, animals, marine organisms, and microorganisms. Although the marine biota accounts for around 50% of the total world biodiversity, but their potential as a rich source of bioactive products and their applications in both pharmaceutical and nutraceutical industries have only recently been identified through several scientific studies. Marine biotechnology is an upcoming area that involves about the study of marine microorganisms and animals including algae, sponges, and coral as a novel source of bioactive substances that can be used in the treatment of various human diseases like cancer, anemia, diarrhea, obesity, diabetes, atopic dermatitis, Crohn,Äôs disease, etc. They are also potential sources of natural antioxidants, colors, immuno-suppressants, enzyme inhibitors, hypocholesterolemic agents, vitamins, enzymes, and antibiotics. However, marine microorganisms have not yet been given the attention they deserve and a very limited scientific data is available on bioactive potential of marine microorganisms. There is still scope for a higher magnitude of research and investigation to explore the potential of both marine organisms and marine microorganisms as producers of novel drugs. This chapter deals with the exploitation of microbes from marine sources as potential sources for various nutraceuticals and their possibilities for applications in variety of diseases and as functional food supplement.
Bioactive Compounds From Marine Organisms
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Author : Mary-Frances Thompson
language : en
Publisher:
Release Date : 1991
Bioactive Compounds From Marine Organisms written by Mary-Frances Thompson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Bioactive compounds categories.
Biomarkers In Marine Organisms
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Author : Ph. Garrigues
language : en
Publisher: Elsevier
Release Date : 2001-11-07
Biomarkers In Marine Organisms written by Ph. Garrigues and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-11-07 with Science categories.
Many previous studies and books have been dedicated to fundamental and developmental aspects of biomarkers. The purpose of this book is to provide, through various case studies, an overview of the practical use of biological markers in marine animals to evaluate the health effects of environmental contamination in marine ecosystems. More precisely, the book presents the results obtained during the development and application of biological markers as indicators of exposure/effect to toxic chemicals in marine environments, using diverse sentinel species such as fish, bivalves and crustaceans. An important aspect is also the publication of technical annexes that describe in detail the experimental procedures developed for both chemical and biochemical measurement.