Epigenetic Regulation Of Skin Development And Regeneration
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Epigenetic Regulation Of Skin Development And Regeneration
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Author : Vladimir A. Botchkarev
language : en
Publisher: Springer
Release Date : 2018-09-03
Epigenetic Regulation Of Skin Development And Regeneration written by Vladimir A. Botchkarev and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-03 with Science categories.
This indispensable volume highlights recent studies identifying epigenetic mechanisms as essential regulators of skin development, stem cell activity and regeneration. Chapters are contributed by leading experts and promote the skin as an accessible model system for studying mechanisms that control organ development and regeneration. The timely discussions contained throughout are of broad relevance to other areas of biology and medicine and can help inform the development of novel therapeutics for skin disorders as well as new approaches to skin regeneration that target the epigenome. Part of the highly successful Stem Cells and Regenerative Medicine series, Epigenetic Regulation of Skin Development and Regeneration uncovers the fundamental significance of epigenetic mechanisms in skin development and regeneration, and emphasizes the development of new therapies for a number of skin disorders, such as pathological conditions of epidermal differentiation, pigmentation and carcinogenesis. At least six categories of researchers will find this book essential, including stem cell, developmental, hair follicle or molecular biologists, and gerontologists or clinical dermatologists.
Epigenetics And Regeneration
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Author :
language : en
Publisher: Academic Press
Release Date : 2019-05-24
Epigenetics And Regeneration written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-24 with Science categories.
Epigenetics and Regeneration compiles the first foundational reference on epigenetic mechanisms governing tissue development, repair, homeostasis, and regeneration, as well as pathways to employ these mechanisms in clinical practice and translational science. In this book, life science researchers, clinicians, and students will discover an interdisciplinary resource bringing together common themes in the field, background overviews, research methods, recent advances, and opportunities for drug discovery. Throughout this volume, special attention is paid to pre-clinical and first clinical studies aimed at increasing the regenerative potential of damaged tissues by epigenetic drugs, as well as innovative, discipline spanning strategies to enhance cell reprogramming. As an all-inclusive, evidence-based volume, Epigenetics and Regeneration will stimulate discussion and boost new research in this fascinating and impactful area of translational epigenetics. Provides a foundational overview of epigenetics in regenerative medicine Examines epigenetic components of tissue regeneration for a variety of organ systems and tissue types, as well as current attempts to employ these mechanisms in clinical practice Offers researchers, students, clinicians, and pharmacologists the tools they need to enhance tissue development, repair, homeostasis, and regeneration and explore new epigenetic therapeutic pathways Features chapter contributions from leading international researchers and clinicians in the fields of epigenetics and regenerative medicine
Mechanisms Of Epigenetic Regulation In Epidermal Keratinocytes During Skin Development
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Author : Valentina Rapisarda
language : en
Publisher:
Release Date : 2014
Mechanisms Of Epigenetic Regulation In Epidermal Keratinocytes During Skin Development written by Valentina Rapisarda and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
Epigenetic Regulation Of Lymphocyte Development
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Author : Cornelis Murre
language : en
Publisher: Springer
Release Date : 2012-02-16
Epigenetic Regulation Of Lymphocyte Development written by Cornelis Murre and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-16 with Medical categories.
The studies described in this volume serve as a starting point to familiarize one self with the multifarious differences in epigenetic designs that orchestrate the progression of developing blood cells. They also may serve as a general paradigm for the mechanisms that underpin the control of eukaryotic gene expression.
Introduction To Epigenetics
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Author : Renato Paro
language : en
Publisher: Springer Nature
Release Date : 2021-03-23
Introduction To Epigenetics written by Renato Paro and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-23 with Science categories.
This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease
Epigenetics And Metabolomics
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Author : Paban K. Agrawala
language : en
Publisher: Elsevier
Release Date : 2021-08-25
Epigenetics And Metabolomics written by Paban K. Agrawala and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-25 with Medical categories.
Epigenetics and Metabolomics, a new volume in the Translational Epigenetics series, offers a synthesized discussion of epigenetic control of metabolic activity, and systems-based approaches for better understanding these mechanisms. Over a dozen chapter authors provide an overview of epigenetics in translational medicine and metabolomics techniques, followed by analyses of epigenetic and metabolomic linkage mechanisms likely to result in effective identification of disease biomarkers, as well as new therapies targeting the removal of the inappropriate epigenetic alterations. Epigenetic interventions in cancer, brain damage, and neuroendocrine disease, among other disorders, are discussed in-depth, with an emphasis on exploring next steps for clinical translation and personalized healthcare. Offers a synthesized discussion of epigenetic regulation of metabolic activity and systems-based approaches to power new research Discusses epigenetic control of metabolic pathways and possible therapeutic targets for cancer, neurodegenerative, and neuroendocrine diseases, among others Provides guidance in epigenomics and metabolomic research methodology
Epigenetics Of Aging
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Author : Trygve O. Tollefsbol
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-11-11
Epigenetics Of Aging written by Trygve O. Tollefsbol and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-11 with Medical categories.
Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.
Regenerative Biology And Medicine
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Author : David L. Stocum
language : en
Publisher: Academic Press
Release Date : 2012-06-07
Regenerative Biology And Medicine written by David L. Stocum and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-07 with Technology & Engineering categories.
Regenerative Biology and Medicine, Second Edition — Winner of a 2013 Highly Commended BMA Medical Book Award for Medicine — discusses the fundamentals of regenerative biology and medicine. It provides a comprehensive overview, which integrates old and new data into an ever-clearer global picture. The book is organized into three parts. Part I discusses the mechanisms and the basic biology of regeneration, while Part II deals with the strategies of regenerative medicine developed for restoring tissue, organ, and appendage structures. Part III reflects on the achievements of regenerative biology and medicine; future challenges; bioethical issues that need to be addressed; and the most promising developments in regenerative medicine. The book is designed for multiple audiences: undergraduate students, graduate students, medical students and postdoctoral fellows, and research investigators interested in an overall synthesis of this field. It will also appeal to investigators from fields not directly related to regenerative biology and medicine, such as chemistry, informatics, computer science, mathematics, physics, and engineering. Highly Commended 2013 BMA Medical Book Award for Medicine Includes coverage of skin, hair, teeth, cornea, and central neural tissues Provides description of regenetive medicine in digestive, respiratory, urogenital, musculoskeletal, and cardiovascular systems Includes amphibians as powerful research models with discussion of appendage regeneration in amphibians and mammals
Epidermal Stem Cell Niche
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Author : Mirna Perez-Moreno
language : en
Publisher: Academic Press
Release Date : 2019-08-09
Epidermal Stem Cell Niche written by Mirna Perez-Moreno and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-09 with Science categories.
Advances in Stem Cells and Their Niches, Volume Three, comprises a compilation of the latest findings on our understanding of skin biology. It extends the current knowledge on skin stem cells and provides in-depth discussions on their unique settings, niches and properties. Chapters in this new release include The biophysical regulation of epidermal fate and function, Epidermal stem cell lineages, Hair shaft progenitors that create a niche for hair pigmentation, Dermal papilla cells control of hair follicle growth and pigmentation, Molecular mechanisms regulating the hair follicle niche, Dermal fibroblasts and their niches and interactions with epidermal stem cells. Contains chapters written by international leaders in skin biology Provides a unique compilation of the latest findings and technologies in basic and translational skin biology Expands current knowledge on the regulation of skin stem cells as isolated entities, focusing on how skin stem cells and lineages of stem cells function in a coordinated manner Provides illustrations and comprehensive analyses of each subject
Functional Foods For Health Maintenance Understanding Their Role In Cancer Prevention
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Author : Saroj Arora
language : en
Publisher: Bentham Science Publishers
Release Date : 2023-08-31
Functional Foods For Health Maintenance Understanding Their Role In Cancer Prevention written by Saroj Arora and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-31 with Medical categories.
The comprehensive information about the inverse relationship between the incidence of cancer and the consumption of natural food has impacted our understanding of the biochemical mechanisms behind cancer and its treatment. Functional Foods for Health Maintenance: Understanding their Role in Cancer Prevention is a review of pre-clinical studies unraveling the chemotherapeutic potential of phytochemicals and other food sources. The editors attempt to summarize the evidence, methods and techniques for identifying specific nutraceuticals and foods capable of interfering and reducing the risk of cancer. The book compiles 19 edited chapters that cover the chemopreventive effects of different phytochemicals, animal and stem cell models for cancer prevention, and novel nanotechnology-based nutraceuticals. The contributors have also highlighted the techniques employed for the detection of cancer with a review on cancer biomarkers. The book is a resource for post-graduate students and researchers working in the field of nutrition, molecular biology, chemoprevention, biochemistry and pharmaceutical sciences.