Epigenetics And Health
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Epigenetics In Health And Disease
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Author : Igor Kovalchuk
language : en
Publisher: FT Press
Release Date : 2012
Epigenetics In Health And Disease written by Igor Kovalchuk and has been published by FT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Juvenile Nonfiction categories.
"After reviewing the field's history and context, the authors introduce and explain each key epigenetic mechanism. Next, they extensively discuss the roles these mechanisms may play in inheritance, development, health and disease, behavior, evolution, ecology, and the interactions of individual organisms with their environments"--Page 4 of cover.
Nutrition Epigenetics And Health
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Author : Burdge Graham
language : en
Publisher: World Scientific
Release Date : 2016-10-07
Nutrition Epigenetics And Health written by Burdge Graham and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-07 with Medical categories.
Epigenetics is emerging as an important factor in risk of diseases of global importance including obesity, cardiovascular disease and cancer. Unlike gene polymorphisms which have been the focus of understanding the role of inherited disease susceptibility for some time, epigenetic can be modified by environmental factors, in particular nutrition. Thus research into the role of epigenetics in disease has substantial potential for explaining the impact of the environmental factors such as diet on disease risk. Since epigenetic processes can be modified by nutrition, it may be possible to modify inappropriate epigenetic marks by nutritional interventions to reduce disease risk. This book will explore current understanding of the interaction between nutrition, epigenetics and disease risk, will place this knowledge in the context of global health and discuss the ethical implications of this research.
Epigenetics In Health And Disease
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Author :
language : en
Publisher: Elsevier
Release Date : 2023-04-03
Epigenetics In Health And Disease written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-03 with Science categories.
Epigenetics in Health and Disease, Volume 197 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on An Introduction to epigenetics in health and disease, State-of-the-art techniques for epigenetics study, Computational biology in epigenetics, Artificial intelligence and machine learning in epigenetics, CRISPR-Cas systems in epigenetics modification for health, Mechanisms of DNA methylation and histone modifications, Non-coding RNA in epigenetics, Role of DNA Methylation in cardiovascular diseases, Role of epigenetics in renal diseases, and much more. Additional chapters update on Histone modifications in fat metabolism and obesity, Role of DNA methylation in diabetes and obesity, Epigenetic regulons in Alzheimer’s disease, Epigenetics in heredity disease, Epigenetics of aging, Epigenetics in cancer development, diagnosis and therapy, Microbiota and epigenetics: health impact, Epigenetics in Fetal Alcohol Spectrum disorder, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Progress in Molecular Biology and Translational Science series Includes the latest information on Epigenetics in Health and Disease
Epigenetics And Health
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Author : Michelle McCulley
language : en
Publisher: John Wiley & Sons
Release Date : 2024-04-02
Epigenetics And Health written by Michelle McCulley and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-02 with Science categories.
Epigenetics and Health An incisive and contemporary discussion of epigenetic phenomena applied to human health and disease Epigenetics and Health: A Practical Guide delivers a thorough and insightful exploration of the basic principles of gene function, gene regulation, and gene expression. The author explains how epigenetic modifications alter gene expression and demonstrate the role played by environmental factors—including nutrition, exercise, toxins, and stress—in gene regulation, as well as their potential health consequences. The book presents current methods for analyzing epigenetic variation, including NGS applications and bioinformatic analysis. Readers will be encouraged to question, analyze, and critically appraise the literature on epigenetics to further develop their understanding. They’ll also find: Explorations of epigenetic mechanisms, homeostasis, and the potential for manipulating the epigenome Practical discussions of methods for epigenetic analyses How to address cancer epigenetics, mental health epigenetics, and guidance on developing an epigenetics research project Epigenetics and Health: A Practical Guide will benefit practicing geneticists and medical geneticists seeking insights into epigenetic phenomena applied to human health and disease.
Molecular Mechanisms And Physiology Of Disease
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Author : Nilanjana Maulik
language : en
Publisher: Springer
Release Date : 2014-05-31
Molecular Mechanisms And Physiology Of Disease written by Nilanjana Maulik and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-31 with Medical categories.
In a simplified form, epigenetics refers to heritable changes in phenotype that are not due to changes in the underlying DNA sequence. In this book, epigenetic mechanisms of regulation and dysregulation in health and disease are explored in great depth. Detailed chapters on epigenetic processes including DNA methylation and chromatin post-translational modifications including potential interventions with DNA methyltransferase inhibitors and histone deacetylase inhibitors are explored in initial chapters. These provide a detailed overview and important background to the entire field. The book is then focussed on epigenetic mechanisms involved in various diseases including anti-inflammatory and autoimmune conditions. Important accounts relating to the effects of epigenetics in metabolic syndrome, cardiovascular disease and asthma are the focus of subsequent chapters. The role of epigenetic dysregulation in malignancy is a current topic of interest and represents an intense field of research. A large component of this book is dedicated to the analysis of aberrant epigenetic processes in carcinogenesis and cancer progression. Further, chapters are focused on emerging cancer prevention using nutritional components and anti-cancer therapies particularly with histone deacetylase inhibitors, which have already been approved for the treatment of cutaneous T-cell lymphoma. The emerging role of nanoparticle preparations, especially in the context of delivering potential epigenetic therapies to target cells in various diseases, is also explored in this book. Overall, this book encompasses a wide range of topics related to epigenetic mechanisms in health and disease and would appeal to anyone with an interest in epigenetics, chromatin biology and emerging epigenetic interventions and therapies.
Nutrition Epigenetics And Health
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Author : Graham Burdge
language : en
Publisher:
Release Date : 2016
Nutrition Epigenetics And Health written by Graham Burdge and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Epigenomics categories.
Epigenetics In Health And Disease Part B
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Author :
language : en
Publisher: Elsevier
Release Date : 2023-07
Epigenetics In Health And Disease Part B written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07 with Science categories.
Epigenetics in Health and Disease, Volume 198 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on An Introduction to epigenetics in health and disease, State-of-the-art techniques for epigenetics study, Computational biology in epigenetics, Artificial intelligence and machine learning in epigenetics, CRISPR-Cas systems in epigenetics modification for health, Mechanisms of DNA methylation and histone modifications, Non-coding RNA in epigenetics, Role of DNA Methylation in cardiovascular diseases, Role of epigenetics in renal diseases, and much more. Additional chapters update on Histone modifications in fat metabolism and obesity, Role of DNA methylation in diabetes and obesity, Epigenetic regulons in Alzheimer's disease, Epigenetics in heredity disease, Epigenetics of aging, Epigenetics in cancer development, diagnosis and therapy, Microbiota and epigenetics: health impact, Epigenetics in Fetal Alcohol Spectrum disorder, and much more.
The Epigenome And Developmental Origins Of Health And Disease
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Author : Cheryl S Rosenfeld
language : en
Publisher: Academic Press
Release Date : 2015-10-10
The Epigenome And Developmental Origins Of Health And Disease written by Cheryl S Rosenfeld and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-10 with Science categories.
The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or to conversely promote the health of the offspring. The book mines the existing literature from a variety of disciplines from toxicology to nutrition to epigenetics to reveal how contrasting maternal in utero environmental changes might be leading to epigenetic convergence and the resulting deleterious phenotypic and physiological effects in our offspring. It is increasingly becoming apparent that even subtle changes in the mother’s diet, stress, and exposure to low concentrations of toxic chemicals at levels deemed safe by the EPA and FDA, such as endocrine disrupting compounds (EDC), can dramatically impact the health of our children, possibly leading to metabolic, cardiovascular, immunological, neurobehavioral disorders, and increased risk for cancer to list but a few examples. Informs how everyday choices pregnant women make can impact child development Ties together how in utero environmental changes may be inducing epigenetic changes in the offspring leading to overlapping phenotypes regardless of the initial insult (toxic, nutrition, or stress) Includes a boxed-in area in each chapter for further references and resources to keep up with the field Features video interviews with the authors and other key leaders in the field
Environmental Epigenomics In Health And Disease
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Author : Randy L Jirtle
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-05-16
Environmental Epigenomics In Health And Disease written by Randy L Jirtle and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-16 with Medical categories.
There are now compelling human epidemiological and animal experimental data that indicate the risk of developing adult-onset complex diseases and neurological disorders are influenced by persistent epigenetic adaptations in response to prenatal and early postnatal exposures to environmental factors. Epigenetics refers to heritable changes in gene function that occur without a change in the sequence of the DNA. The main components of the epigenetic code are DNA methylation, histone modifications, and non-coding RNAs. The epigenetic programs are established as stem cell differentiate during embryogenesis, and they are normally faithfully reproduced during mitosis. Moreover, they can also be maintained during meiosis, resulting in epigenetic transgenerational disease inheritance, and also potentially introducing phenotypic variation that is selected for in the evolution of new species. The objective of this book is to provide evidence that environmental exposures during early development can alter the risk of developing medical conditions, such as asthma, autism, cancer, cardiovascular disease, diabetes, obesity, and schizophrenia later in life by modifying the epigenome.
Epigenetics And Human Health
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Author : Alexander Haslberger
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-24
Epigenetics And Human Health written by Alexander Haslberger and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-24 with Science categories.
After first introducing the concept of epigenetics, this handbook and ready reference provides an overview of the main research on epigenetics. It adopts a multidisciplinary approach, involving molecular biology, molecular epidemiology and nutritional science, with a special focus of the book is on disease prevention and treatment. Of interest to all healthcare-related professionals as well as nutritionists, and the medical community focusing on disease prevention.