Epigenetics In Human Reproduction And Development


Epigenetics In Human Reproduction And Development
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Epigenetics In Human Reproduction And Development


Epigenetics In Human Reproduction And Development
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Author : Naumova Anna K
language : en
Publisher: World Scientific
Release Date : 2016-12-20

Epigenetics In Human Reproduction And Development written by Naumova Anna K and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-20 with Medical categories.


Epigenetics is defined as heritable changes that do not affect the DNA sequence but influence gene expression. Epigenetic changes occur at the levels of DNA, histone, protein, and chromatin structures. Proper epigenetic modifications are essential for cell differentiation and function during development, while some epigenetic modifications are passed on from parents to offspring through gametes. Therefore, alterations of epigenetic states would have serious consequences for human development and health. This realization and the advent of new technologies have encouraged the advance of epigenetic studies in recent years. Nonetheless, many aspects of epigenetics, such as regulatory mechanisms and evolutional advantages, remain to be better understood. Written by 26 scientists at the forefront of epigenetics research, this book discusses the different facets of epigenetics: from gametogenesis to child development, as well as from mechanistic studies in animal models to reviews of human clinical data.



Epigenetics In Human Reproduction And Development


Epigenetics In Human Reproduction And Development
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Author : Anna K. Naumova
language : en
Publisher:
Release Date : 2016

Epigenetics In Human Reproduction And Development written by Anna K. Naumova and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with HEALTH & FITNESS categories.


"Epigenetics is defined as heritable changes that do not affect the DNA sequence but influence gene expression. Epigenetic changes occur at the levels of DNA, histone, protein, and chromatin structures. Proper epigenetic modifications are essential for cell differentiation and function during development, while some epigenetic modifications are passed on from parents to offspring through gametes. Therefore, alterations of epigenetic states would have serious consequences for human development and health. This realization and the advent of new technologies have encouraged the advance of epigenetic studies in recent years. Nonetheless, many aspects of epigenetics, such as regulatory mechanisms and evolutional advantages, remain to be better understood. Written by 26 scientists at the forefront of epigenetics research, this book discusses the different facets of epigenetics: from gametogenesis to child development, as well as from mechanistic studies in animal models to reviews of human clinical data."--Publisher's website.



Epigenetics And Human Reproduction


Epigenetics And Human Reproduction
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Author : Sophie Rousseaux
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-11-03

Epigenetics And Human Reproduction written by Sophie Rousseaux and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-03 with Medical categories.


Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the ‘Epigenetics and Human Health’ series discusses the role of epigenetics in human reproduction



Epigenetics And Human Reproduction


Epigenetics And Human Reproduction
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Author : Sophie Rousseaux
language : en
Publisher: Springer
Release Date : 2010-11-05

Epigenetics And Human Reproduction written by Sophie Rousseaux and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-05 with Medical categories.


Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the ‘Epigenetics and Human Health’ series discusses the role of epigenetics in human reproduction



Epigenetics And Reproductive Health


Epigenetics And Reproductive Health
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Author :
language : en
Publisher: Academic Press
Release Date : 2020-09-12

Epigenetics And Reproductive Health written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-12 with Medical categories.


Epigenetics and Reproductive Health, a new volume in the Translational Epigenetics series, provides a thorough overview and discussion of epigenetics in reproduction and implications for reproductive medicine. Twenty international researchers discuss epigenetic mechanisms operating during the formation of male and female gametes, fertilization and subsequent embryo and placental development, particularly in mammals and transgenerational epigenetic inheritance. This volume also addresses aberrant epigenetic changes influencing male and female infertility, pregnancy related disorders, and those potentially linked to therapeutic manipulations and assisted reproductive technologies. Emphasis is placed on identifying biomarkers for early detection of aberrant epigenetic mechanisms. Later chapters examine the possibility of correcting these epigenetic dysfunctions, as well as current challenges and next steps in research, enabling new translational discoveries and efforts towards developing therapeutics. Thoroughly examines the influence of aberrant epigenetics during gametogenesis and embryogenesis, affecting parents, gametes and embryos, offspring and future generations Explores health outcomes for reproductive senescence, endocrine disruption, testicular cancer, prostrate cancer, breast cancer, ovarian, cancer, endometrial cancer and cervical cancers Features chapter contributions from international researchers in the field



Epigenetics And Epigenomics


Epigenetics And Epigenomics
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Author : Christopher J. Payne
language : en
Publisher: BoD – Books on Demand
Release Date : 2014-04-29

Epigenetics And Epigenomics written by Christopher J. Payne and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-29 with Medical categories.


The book aims to provide an overview of current knowledge regarding epigenetics and epigenomics. Included are reviews on the role of epigenetics in the development and pathogenesis of the vascular endothelium and nervous system, as well as our current understanding of the potential etiologies of Autism Spectrum Disorders. Additional chapters are devoted to DNA methylation, genomic imprinting and human reproduction. A discussion of the role of the epigenome in cancer prevention and polyphenols is also included. Authors provide research findings from both human data and animal model studies. This book will be of interest to scientists, physicians and lay readers wishing to review recent developments in the field of epigenetics and epigenomics.



Epigenetics And Assisted Reproduction


Epigenetics And Assisted Reproduction
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Author : Cristina Camprubí
language : en
Publisher: CRC Press
Release Date : 2018-09-03

Epigenetics And Assisted Reproduction written by Cristina Camprubí and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-03 with Medical categories.


Epigenetics is the study of how certain genes are activated without modification at the DNA sequence level, resulting in genetically similar individuals having different clinical outcomes. As contemporary medicine increasingly aims to personalize the medical approach to a patient's genetic profile, the factors that can affect which genes are expressed also increase in importance and relevance to the clinician. This text from experts will give the clinician in Reproductive Medicine a reliable grounding in current thinking and research on this fast-moving topic, with many clinical implications.



Animal Models And Human Reproduction


Animal Models And Human Reproduction
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Author : Heide Schatten
language : en
Publisher: John Wiley & Sons
Release Date : 2017-01-12

Animal Models And Human Reproduction written by Heide Schatten and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-12 with Science categories.


Our knowledge of reproductive biology has increased enormously in recent years on cellular, molecular, and genetic levels, leading to significant breakthroughs that have directly benefitted in vitro fertilization (IVF) and other assisted reproductive technologies (ART) in humans and animal systems. Animal Models and Human Reproduction presents a comprehensive reference that reflects the latest scientific research being done in human reproductive biology utilizing domestic animal models. Chapters on canine, equine, cow, pig, frog, and mouse models of reproduction reflect frontier research in placental biology, ovarian function and fertility, non-coding RNAs in gametogenesis, oocyte and embryo metabolism, fertilization, cryopreservation, signal transduction pathways, chromatin dynamics, epigenetics, reproductive aging, and inflammation. Chapters on non-human primate models also highlight recent advancements into such issues as human in vitro fertilization (IVF) and assisted reproductive technologies (ART). This book offers animal scientists, reproductive biology scientists, clinicians and practitioners, invaluable insights into a wide range of issues at the forefront of human reproductive health.



Human Reproductive And Prenatal Genetics


Human Reproductive And Prenatal Genetics
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Author : Peter C.K. Leung
language : en
Publisher: Elsevier
Release Date : 2023-03-22

Human Reproductive And Prenatal Genetics written by Peter C.K. Leung and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-22 with Science categories.


Human Reproductive and Prenatal Genetics, Second Edition provides application-driven coverage of key topics in human reproductive and prenatal genetics, including genetic control underlying the development of the reproductive tracts and gametogenesis, the genetics of fertilization and implantation, the genetic basis of female and male infertility, as well as genetic and epigenetic aspects of assisted reproduction. Also examined are the genetics and epigenetics of the placenta in normal and abnormal pregnancy, preimplantation genetic diagnosis and screening, and cutting-edge advances in noninvasive prenatal screening, prenatal genetic counseling, and bioethical and medicolegal aspects of relevance in the lab and clinic. This new edition has been fully revised to address new and evolving technologies in human reproductive genetics, with new chapters added on chromatin landscapes and sex determination, genetic alterations of placental development and preeclampsia, metabolism and inflammation in PCOS, pre-implantational genetic testing, maternal genetic disorders, bioethics, and future applications. Features chapter contributions from leading international scientists and clinicians Provides in-depth coverage of key topics in human reproductive and prenatal genetics, including genetic controls, fertilization, placental development, embryo implantation, in vitro culture of the human embryo for the study of post-implantation development, and more Identifies how researchers and clinicians can implement the latest genetic, epigenetic, and –omics-based approaches Includes all new chapters on evolving technologies and recent genetic discoveries of relevance to reproductive medicine



Textbook Of Human Reproductive Genetics


Textbook Of Human Reproductive Genetics
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Author : Stéphane Viville
language : en
Publisher: Cambridge University Press
Release Date : 2022-12-31

Textbook Of Human Reproductive Genetics written by Stéphane Viville and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-31 with Medical categories.


This book combines genetics, reproductive biology and medicine for an integrative view of the emerging specialism of reproductive genetics.