Epithelial Mesenchymal Transitions
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The Epithelial To Mesenchymal Transition
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Author : Kyra Campbell
language : en
Publisher:
Release Date : 2021
The Epithelial To Mesenchymal Transition written by Kyra Campbell and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Cytology categories.
Epithelial Mesenchymal Transitions
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Author : Donald F. Newgreen
language : en
Publisher:
Release Date : 1995
Epithelial Mesenchymal Transitions written by Donald F. Newgreen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with categories.
Recent Progress In Epithelial Mesenchymal Transitions
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Author : Donald F. Newgreen
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 2005
Recent Progress In Epithelial Mesenchymal Transitions written by Donald F. Newgreen and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Cell differentiation categories.
The concept of the epithelial-mesenchymal transition (EMT) provides a basis for understanding complex changes in gene expression, molecular function and cell behaviour. This field has undergone explosive growth in the last few years as the concept has spread from developmental biology to the pathologies of cancer and fibrosis. As scientists are on the verge of being able to control or mitigate the process of EMT in some pathological conditions, understanding of its fundamental mechanisms is of vital importance. This special issue brings together selected reviews and new data from the Boden Conference on Epithelial-Mesenchymal Transitions. The reviews highlight developmental, cancer and pathological EMTs, and are rich in detail at the cell and molecular levels. The publication is aimed at cancer biologists, pathologists and developmental biologists who are interested in why cells begin to move, and the genes and molecules involved in this process.
The Epithelial To Mesenchymal Transition Emt In Cancer
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Author : Joëlle Roche
language : en
Publisher: MDPI
Release Date : 2018-04-09
The Epithelial To Mesenchymal Transition Emt In Cancer written by Joëlle Roche and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-09 with Electronic book categories.
This book is a printed edition of the Special Issue "The Epithelial-to-Mesenchymal Transition (EMT) in Cancer" that was published in Cancers
The Epithelial To Mesenchymal Transition
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Author : Kyra Campbell
language : en
Publisher: Humana
Release Date : 2020-10-28
The Epithelial To Mesenchymal Transition written by Kyra Campbell and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-28 with Science categories.
This volume details a comprehensive range of methods for imaging epithelial-to-mesechymal transition (EMT)/MET in in vivo systems, and methods to leverage these systems to dissect the underlying mechanisms. Chapters guide readers through studying different features of epithelial-mesenchymal plasticity, past and future research of the EMT, in vivo systems, and in vivo imaging. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, The Epithelial-to Mesenchymal Transition: Methods and Protocols aims to provide methods in EMT will help to unite and drive research in this exciting field forwards.
Rise And Fall Of Epithelial Phenotype
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Author : Pierre Savagner
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-07-05
Rise And Fall Of Epithelial Phenotype written by Pierre Savagner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-05 with Science categories.
Epithelial phenotype is a dynamic stage of differentiation that can be modulated during several physiological or pathological events. The rapid conversion to a mesenchymal-like phenotype is called an epithelial-mesenchymal transition (EMT). The Rise and Fall of Epithelial Phenotype is the first book to comprehensively introduce the concept of EMT. The first part of this volume describes main examples and models and explains their physiological relevance. These examples include hydra morphogenesis, gastrulation in mouse, drosophila and sea urchin, as well as neural crest cell migration and heart morphogenesis in vertebrates. Part two reviews in detail, specific EMT molecular pathways covering extracellular induction, transduction and transcription response and modulation of cell-cell adhesion structures. It emphasizes new specific pathways with potential medical applications. EMTs can also be linked to pathological events such as wound healing and cancer progression, as detailed in this section of the book.
Advances In Epithelial Mesenchymal Transitions
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Author : Erik W. Thompson
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 2007
Advances In Epithelial Mesenchymal Transitions written by Erik W. Thompson and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
The concept of epithelial-mesenchymal transitions (EMT) has brought valuable insights to the study of complex processes involved in early embryo development, wound healing, carcinoma progression or kidney fibrosis. Major advances are reported in identifying new model systems, transcriptional regulators (including chromatin structure and microRNA), specific signaling pathways, and effector molecules. In this special issue, recent developments in the EMT field are reviewed, including the first localizations of Snail proteins in human cancers. Snail signaling and targets are carefully explored in several systems. Another emerging signaling pathway discussed involves TGF-beta. Several new concepts are consolidated including partial EMT, resulting in a metastable phenotype in cancer systems, and reversed EMT, described during bladder cancer progression as a mesenchymal-epithelial transition. Some of the papers focus on the first therapeutic approaches and different microarray analysis approaches specifically targeting the EMT process. Basic and clinical reseachers, clinicians as well as graduate and PhD students in the fields of cell and developmental biology, oncology and nephrology will appreciate this multidisciplinary and up-to-date overview of the EMT process.
Epithelial Mesenchymal Transitions New Advances In Development Fibrosis And Cancer
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Author : Erik W. Thompson
language : en
Publisher:
Release Date : 2010-12-13
Epithelial Mesenchymal Transitions New Advances In Development Fibrosis And Cancer written by Erik W. Thompson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-13 with categories.
This special issue represents a progression through signaling processes, development, fibrosis and cancer, illustrating common underlying mechanisms and highlighting the growing recognition of therapeutic possibilities. Novel molecular pathways are shown in the context of known regulators, and many articles offer specific insights into therapeutic targeting. Not surprisingly, several articles relate to the signaling pathways activated by the common anchor transforming growth factor (TGF)-beta in relation to epithelial-mesenchymal transition (EMT). A number of new mechanisms with therapeutic implications are described, specifically the interplay between the non-Smad PI3 kinase-Akt-mTOR axis and EMT-associated invasion in response to TGF-beta, the unexpected role of c-Abl in repressing TGF-beta1-induced EMT, the cooperativity between oncostatin M, hepatocyte growth factor and TGF-beta1 in lung carcinoma EMT, and the roles of dystroglycan and periostin in developmental EMT associated with gastrulation and palate fusion, respectively. Collectively, the issue presents the full spectrum of interest in EMT today.
Epithelial Mesenchymal Transition
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Author : Eric W. Thomson
language : en
Publisher:
Release Date : 2008
Epithelial Mesenchymal Transition written by Eric W. Thomson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.
Epithelial Mesenchymal Transitions
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Author : D. F. Newgreen
language : en
Publisher:
Release Date : 2017-02-23
Epithelial Mesenchymal Transitions written by D. F. Newgreen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-23 with categories.
This special topic issue presents a selection of papers from the International EMT meeting held in Melbourne, October, 2015. The recent TEMTIA meetings have identified the emerging trends of big data and complex systems biology. A specific focus is on the positive impact that new methods of systems analysis can have on identifying novel regulators of EMT. There is also emphasis on the utility of mathematical models for assessing potential effects of EMT on the emergent behavior of tissues and in discriminating between stochastic and deterministic processes. Rather than the traditional bastions of EMT, such as development, cancer, fibrosis, wound healing, etc., the TEMTIA-VII session themes were based on concepts such as plasticity, stemness and self-renewal, signalling networks and transcription factors, and systems biology.