Estrogen Action Selective Estrogen Receptor Modulators And Women S Health Progress And Promise
DOWNLOAD
AUDIOBOOK
READ ONLINE
Download Estrogen Action Selective Estrogen Receptor Modulators And Women S Health Progress And Promise PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Estrogen Action Selective Estrogen Receptor Modulators And Women S Health Progress And Promise book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Estrogen Action Selective Estrogen Receptor Modulators And Women S Health Progress And Promise
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : V Craig Jordan
language : en
Publisher: World Scientific
Release Date : 2013-05-27
Estrogen Action Selective Estrogen Receptor Modulators And Women S Health Progress And Promise written by V Craig Jordan and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-27 with Science categories.
This volume presents the evolution of the authors' ideas about estrogen action and its modulation by a new group of drugs called SERMs (Selective Estrogen Receptor Modulators). The pioneering SERMs — tamoxifen and raloxifene — are known to have saved the lives of millions of women around the world and improved the health of millions more. Estrogen is the central hormone of women's health and reproduction. The book is a journey through 40 years of discovery and success in advancing women's health, with the prospect of improved innovation through medicinal chemistry for the future.
Selective Estrogen Receptor Modulators
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Andrea Manni
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-01-18
Selective Estrogen Receptor Modulators written by Andrea Manni and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-01-18 with Medical categories.
Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs. The basic science chapters of the book focus-with an eye to the development of the ideal SERM-on the complex mechanisms of estrogen action, including ligand-dependent conformational changes in alpha and beta, and the recruitment of co-activators and co-repressors which modulate the estrogen receptor transcriptional activity and contribute to its crosstalk with growth factor signaling. The clinical presentation reviews the data accumulated on currently available SERMs, primarily tamoxifen and raloxifene, in cancer treatment and prevention, as well as their effects on the reproductive, vascular, skeletal, and central nervous systems. A tentative approach to menopause-related health issues is also provided for women with and without a previous diagnosis of localized breast cancer.
Women S Health Research
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2010-10-27
Women S Health Research written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-27 with Medical categories.
Even though slightly over half of the U.S. population is female, medical research historically has neglected the health needs of women. However, over the past two decades, there have been major changes in government support of women's health research-in policies, regulations, and the organization of research efforts. To assess the impact of these changes, Congress directed the Department of Health and Human Services (HHS) to ask the IOM to examine what has been learned from that research and how well it has been put into practice as well as communicated to both providers and women. Women's Health Research finds that women's health research has contributed to significant progress over the past 20 years in lessening the burden of disease and reducing deaths from some conditions, while other conditions have seen only moderate change or even little or no change. Gaps remain, both in research areas and in the application of results to benefit women in general and across multiple population groups. Given the many and significant roles women play in our society, maintaining support for women's health research and enhancing its impact are not only in the interest of women, they are in the interest of us all.
Estrogen Receptor And Breast Cancer
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Xiaoting Zhang
language : en
Publisher: Humana Press
Release Date : 2019-11-08
Estrogen Receptor And Breast Cancer written by Xiaoting Zhang and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-08 with categories.
The discovery of ER by Dr. Elwood Jensen exactly 60 years ago has not only led to the birth of a whole new vital nuclear receptor research field but also made a rapid, direct and lasting impact on the treatment and prevention of breast cancer. Since that landmark discovery, tremendous progress has been made in our understanding of the molecular functions of ER and development of targeted therapies against ER pathways for breast cancer treatment. However, there is currently no book available addressing these discoveries and recent advancement in a historical and systematic fashion. This book is intended to provide comprehensive, most up-to-date information on the history and recent advancement of ER and breast cancer by world renowned leaders in the field. These chapters include the history of the discovery of ER; physiological and pathological roles of ER; recent discovery of ER cistrome, transcriptome and its regulation of noncoding RNAs such as microRNAs and enhancer RNAs in breast cancer; development and clinical practices of the first targeted therapy Tamoxifen and other antiestrogens for breast cancer treatment; structural basis of ER and antiestrogen actions; molecular insights into endocrine resistance; the role of ER mutants, ER-beta and environmental estrogens in breast cancer; and emerging state-of-the-art therapeutic approaches currently in development to overcome treatment resistance and future perspectives. The book will provide undergraduate and graduate students, basic scientists and clinical cancer researchers, residents, fellows, as well as clinicians, oncology educators and the general public a thorough and authoritative review of these exciting topics.
Drug Discovery Approaches For The Treatment Of Neurodegenerative Disorders
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Adeboye Adejare
language : en
Publisher: Academic Press
Release Date : 2016-09-20
Drug Discovery Approaches For The Treatment Of Neurodegenerative Disorders written by Adeboye Adejare and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-20 with Medical categories.
Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer’s Disease examines the drug discovery process for neurodegenerative diseases by focusing specifically on Alzheimer’s Disease and illustrating the paradigm necessary to ensure future research and treatment success. The book explores diagnosis, epidemiology, drug discovery strategies, current therapeutics, and much more to provide a holistic approach to the discovery, development, and treatment of Alzheimer’s Disease. Through its coverage of the latest research in targeted drug design, preclinical studies, and mouse and rat models, the book is a must-have resource for all pharmaceutical scientists, pharmacologists, neuroscientists, and clinical researchers working in this area. It illustrates why these drugs tend to fail at the clinical stage, and examines Alzheimer’s Disease within the overall context of improving the drug discovery process for the treatment of other neurodegenerative disorders. Provides a compilation of chemical considerations required in drug discovery for the treatment of neurodegenerative disorders Examines different classes of compounds currently being used in discovery and development stages Explores in vitro and in vivo models with respect to their ability to translate these models to human conditions Distills the most significant information across multiple areas of Alzheimer’s disease research to provide a single, comprehensive, and balanced resource
The Female Brain
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Louann Brizendine
language : en
Publisher: Random House
Release Date : 2009-05-04
The Female Brain written by Louann Brizendine and has been published by Random House this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-04 with Science categories.
Accessible, fun and compelling, and based on more than three decades of research, The Female Brain will help women to better understand themselves - and the men in their lives. In this groundbreaking book, Dr Louann Brizendine describes the uniquely flexible structure of the female brain and its constant, dynamic state of change - the key difference that separates it from that of the male - and reveals how women think, what they value, how they communicate, and whom they'll love. She also reveals the neurological explanations behind why... - A woman remembers fights that a man insists never happened... - Thoughts about sex enter a woman's brain perhaps once every couple of days, but may enter a man's brain up to once every minute... - A woman's brain goes on high alert during pregnancy - and stays that way long after giving birth... - A woman over 50 is more likely to initiate divorce than a man... - Women tend to know what people are feeling, while men can't spot an emotion unless someone cries or threatens them with bodily harm!
Long Term Tamoxifen Treatment For Breast Cancer
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Virgil Craig Jordan
language : en
Publisher: Univ of Wisconsin Press
Release Date : 1994
Long Term Tamoxifen Treatment For Breast Cancer written by Virgil Craig Jordan and has been published by Univ of Wisconsin Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Breast categories.
During the past twenty years tamoxifen has become the most widely prescribed and most successful drug used in the treatment of breast cancer. In this volume, editor V. Craig Jordan provides articles that trace the development, pharmacology, and clinical research surrounding this drug which, by the year 2000, could be used to treat as many as one million women annually. Drawing from research conducted by specialists in the United States, the United Kingdom, and Italy, the series of articles describes the clinical testing of tamoxifen, highlighting the benefits. Studies show that tamoxifen lowers cholesterol and can potentially protect women against osteoporosis and fatal coronary heart disease. Equally important is a discussion of side effects and possible drug interactions and how these issues relate to patient concerns. An investigation of the development of a new class of drugs for use after tamoxifen fails provides valuable insight into future treatments, as the contributers consider possible resistance to tamoxifen. This volume provides invaluable information for physicians and surgeons who care for patients with breast cancer and for women interested in exploring this therapeutic dimension.
Anticancer Drug Development
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Bruce C. Baguley
language : en
Publisher: Elsevier
Release Date : 2001-11-17
Anticancer Drug Development written by Bruce C. Baguley and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-11-17 with Medical categories.
Here in a single source is a complete spectrum of ideas on the development of new anticancer drugs. Containing concise reviews of multidisciplinary fields of research, this book offers a wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death. Detailed descriptions of sources for new drugs and methods for testing and clinical trial design are also provided. One work that can be consulted for all aspects of anticancer drug development Concise reviews of research fields, combined with practical scientific detail, written by internationally respected experts A wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death Detailed descriptions of the sources of new anticancer drugs, including combinatorial chemistry, phage display, and natural products Discussion of how new drugs can be tested in preclinical systems, including the latest technology of robotic assay systems, cell culture, and experimental animal techniques Hundreds of references that allow the reader to access relevant scientific and medical literature Clear illustrations, some in color, that provide both understanding of the field and material for teaching
Research On Women S Health
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author :
language : en
Publisher:
Release Date : 1997
Research On Women S Health written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Women categories.
Clinical Gynecology
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Eric J. Bieber
language : en
Publisher: Cambridge University Press
Release Date : 2015-04-23
Clinical Gynecology written by Eric J. Bieber and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-23 with Medical categories.
Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.