Estrogens And Memory
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Estrogens And Memory
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Author : Karyn M. Frick
language : en
Publisher: Oxford University Press, USA
Release Date : 2020
Estrogens And Memory written by Karyn M. Frick and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Psychology categories.
"A book about the influence of estrogens on memory would have been unthinkable as recently as 30 years ago. Although a few small studies in the late 1970's reported a beneficial effect of estrogens on memory in human women (Hackman and Galbraith, 1976; Fedor-Freybergh, 1977), examination of the role of estrogens in memory did not truly capture more widespread attention until the pioneering work of Barbara Sherwin and colleagues in 1988 and beyond. In her initial paper, Sherwin showed that bilateral removal of the ovaries (aka surgical menopause) led to impaired short-term and long-term memory, whereas treatment of surgically menopausal women with estradiol alone, testosterone alone, or estradiol plus testosterone prevented this decline (Sherwin, 1988). As a search for the terms "estrogen" and "memory" in PubMed illustrates, well over 2000 papers have been published on the subject of estrogens and memory in the ensuing decades. The vast majority of these studies have focused on the hippocampus, a bilateral medial temporal lobe structure essential for the formation of episodic memories, particularly those with spatial, contextual, relational, temporal, and recognition components (Olton et al., 1979; Morris et al., 1982; Kim and Fanselow, 1992; Squire, 1992; Cohen and Stackman, 2015; Tonegawa et al., 2015; Eichenbaum, 2017). Although various forms of learning and memory are mediated by numerous brain regions, including the prefrontal cortex, medial temporal lobe cortices, amygdala, striatum, and cerebellum, the hippocampus has received the lion's share of attention due to its central importance for episodic memory formation. Hippocampal damage produces profound retrograde amnesia for facts and events, as well as anterograde amnesia for new information and impairments in spatial navigation (Winocur, 1990; Anagnostaras et al., 2001; Clark et al., 2002; Gilboa et al., 2006). Hippocampal dysfunction in middle-aged and aged subjects is a primary contributor to age-related memory decline (Golumb et al., 1996; Grady et al., 2003; Apostolova et al., 2010; Burke and Barnes, 2010; Small et al., 2011; Yassa et al., 2011), and has also been implicated in the cognitive impairments observed in diseases such as schizophrenia and depression (Small et al., 2011; Nakahara et al., 2018; Santos et al., 2018; Ott et al., 2019). Moreover, the hippocampi of patients with Alzheimer's disease are substantially atrophied and burdened with copious amounts of amyloid plaques and neurofibrillary tangles, the hallmark pathologies of this insidious disease (Hyman et al., 1984; Walsh and Selkoe, 2004; Selkoe and Hardy, 2016). As such, understanding how estrogens influence hippocampal functioning may provide important insights not only about the fundamental neurobiology of memory processes, but also into the etiology of neuropsychiatric and neurodegenerative diseases"--
Hormones Cognition And Dementia
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Author : Eef Hogervorst
language : en
Publisher: Cambridge University Press
Release Date : 2009-09-24
Hormones Cognition And Dementia written by Eef Hogervorst and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-24 with Medical categories.
Basic and clinical research on sex steroids, ageing, and cognition to integrate existing findings with emerging data.
The Effects Of Estrogen On Brain Function
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Author : Natalie L. Rasgon
language : en
Publisher: JHU Press
Release Date : 2006-05-05
The Effects Of Estrogen On Brain Function written by Natalie L. Rasgon and has been published by JHU Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-05-05 with Health & Fitness categories.
D., University of Southern California--Julie A. Dumas "Sex Roles"
Estrogen Memory Menopause
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Author : Gayatri Devi
language : en
Publisher: Alphasigma
Release Date : 2000-01-01
Estrogen Memory Menopause written by Gayatri Devi and has been published by Alphasigma this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-01-01 with Menopause categories.
Menopause And The Mind
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Author : Claire L. Warga
language : en
Publisher:
Release Date : 1999
Menopause And The Mind written by Claire L. Warga and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Cognition disorders categories.
"Menopause and the Mind gives every woman the survival kit she needs to manage the thinking and memory symptoms - long overlooked by the medical establishment - that accompany the onset of perimenopause and menopause." "Neuropsychologist Claire Warga provides the first scientific explanation for this common "hormonal misconnection" syndrome. Drawing upon recent brain and clinical research, she shows that forgetfulness, malapropisms, and lost concentration are not manifestations of dementia or senility: instead, they result from the depletion of estrogen in the brain cells of women as they enter perimenopause and menopause. Armed with this knowledge, Warga offers women a breakthrough plan for regaining control and confidence in their minds." "Warga explains the full range of thinking, speech, short- and long-term memory, behavior, spatial, and time sense symptoms in extensive detail, complete with an array of examples. Most important are a self-screening test and symptom chart that every women can use to understand the extent of her symptoms and accurately assess her condition, with or without her ob/gyn. Women can also make practical use of Warga's detailed guide to treatment options, which include estrogen therapy, dietary and behavioral changes, and techniques for improving memory."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved
Estrogens Advances In Research And Application 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09
Estrogens Advances In Research And Application 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Medical categories.
Estrogens: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Estrogens in a concise format. The editors have built Estrogens: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Estrogens in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Estrogens: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Estrogen Effects In Psychiatric Disorders
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Author : Niels Bergemann
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-12-27
Estrogen Effects In Psychiatric Disorders written by Niels Bergemann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-27 with Medical categories.
A number of studies, mostly focusing on estrogen replacement therapy in women, have reported beneficial actions of these hormones on various neurobiological and neuropathological parameters in health and disease. Recent research has focused on gender differences and there is increasing evidence that estrogens exert protective effects in schizophrenia. Hormonal fluctuations or lack of estrogen may increase the risk of depression among vulnerable women. Treatment of depression with estrogen may stabilize and restore disrupted homeostasis – as during post-partum, premenstrual, or perimenopausal conditions – and act as a psychomodulator to offset vulnerability to dysphoric mood when estrogen levels are significantly decreased, as in the case of postmenopausal women. Studies on the effect of estrogens on Alzheimer’s Disease are still rather controversial, they do, however, facilitate the hypothesis that estrogens may have a modifying effect on the onset and course of AD, at least in subgroups of patients.
Cognitive Performance And Menopause
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Author : Paula Alhola
language : en
Publisher:
Release Date : 2007
Cognitive Performance And Menopause written by Paula Alhola and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Cognition categories.
Menopause And The Mind
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Author : Claire L. Warga
language : en
Publisher: Simon and Schuster
Release Date : 2000-04-20
Menopause And The Mind written by Claire L. Warga and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-04-20 with Health & Fitness categories.
An essential guide for every woman over the age of 30, this book focuses on one of the least understood, and most ignored, aspects of the aging process--the cognitive problems that accompany the decline of estrogen levels.
Brain Aromatase Estrogens And Behavior
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Author : Jacques Balthazart
language : en
Publisher: Oxford University Press
Release Date : 2012-09-21
Brain Aromatase Estrogens And Behavior written by Jacques Balthazart and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-21 with Psychology categories.
It is well known that the class of steroid hormones known as estrogens have powerful effects on organs related to reproduction such as the uterus and the breast. What is less well known is that estrogens also profoundly modulate brain function and behavior. Estrogens, such as estradiol, can occur in brain as the result of ovarian secretion of the hormone into the blood that then finds its way to the brain. In male vertebrates, the testes secrete androgens, such as testosterone, into the blood and this class of steroid hormones can be converted into estrogens in the brain via the action of the enzyme aromatase which is expressed in the male brain in many species. Finally estradiol can be synthesized de novo from cholesterol as it has been shown in a variety of species that all the enzymes required to synthesize estrogens are expressed in the brain. This book collects chapters by experts in the field that considers, how estradiol is synthesized in the brain and what its effects are on a variety of behaviors. Special attention is paid to the enzyme aromatase that is distributed in discrete regions of the brain and is highly regulated in a sex specific and seasonal specific manner. Recently it has become clear that estrogens can act in the brain at two very different time scales, one is rather long lasting (days to weeks) and involves the modulation of gene transcription by the hormone-receptor complex. A second mode of action is much quicker and involves the action of estrogens on cell membranes that can result in effects on second messenger systems and ultimately behavior within minutes. Thus this book highlights novel views of estrogen action that are still under-appreciated namely that estrogens have significant effects on the male brain and that they can act on two very different times scales. This volume will be of interest to both basic researchers and clinicians interested in the action of estrogens.