Etiology Of Acute Leukemias In Children


Etiology Of Acute Leukemias In Children
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Etiology Of Acute Leukemias In Children


Etiology Of Acute Leukemias In Children
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Author : Juan Manuel Mejía-Aranguré
language : en
Publisher: Springer
Release Date : 2016-03-18

Etiology Of Acute Leukemias In Children written by Juan Manuel Mejía-Aranguré and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-18 with Medical categories.


Childhood acute leukemias are one of the main causes of death in children aged 1 to 14 years in some countries; and unfortunately, we have been unable to prevent it. Certainly, a good parcel of it is due to the poor understanding about its etiology. This book aims to describe the most important theories and hypothesis regarding childhood acute leukemia. Written by the most outstanding researchers in the field, this book intends to contribute to a greater understanding of the etiology of this disease. It goes beyond the simple and common analysis of risk factors, which hardly allows us to draw definite conclusions. By addressing the etiology of the disease, discussing from molecular biology until epidemiology and clinical manifestations, this book will guide present and future approaches, contributing for a better clinical management of leukemia in children. The knowledge regarding etiology is a crucial step for a better evaluation, prevention and treatment of a disease. Thus, this book finally intends to provide such knowledge, allowing physicians and practitioners to a better manage of childhood acute leukemias.



Clinical Epidemiology Of Acute Lymphoblastic Leukemia


Clinical Epidemiology Of Acute Lymphoblastic Leukemia
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Author : Juan Manuel Mejia-Arangure
language : en
Publisher: BoD – Books on Demand
Release Date : 2013-04-17

Clinical Epidemiology Of Acute Lymphoblastic Leukemia written by Juan Manuel Mejia-Arangure and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Medical categories.


This book describes different perspectives of childhood acute lymphoblastic leukemia. The approach includes aspects of molecular epidemiology, particularly molecular features that influence the genesis and prognosis of the disease. Some aspects of the prognosis of lymphoblastic leukemias are very detailed, highlighting the use of molecular biology in the early identification of complications that may occur in diseased patients. The authors of the present book conform a Mexican group who identifies the causes of leukemia, and they summarize their experience in research, results and proposals for future studies. A causal model is included in which the authors hypothesized the origin of acute lymphoblastic leukemias, particularly in children. This hypothesis can be useful to better understand other cancers during childhood. This book will help the reader to identify different molecular aspects involved in leukemia, and its relation to the development and evolution of the disease.



Childhood Acute Lymphoblastic Leukemia


Childhood Acute Lymphoblastic Leukemia
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Author : Ajay Vora
language : en
Publisher: Springer
Release Date : 2017-04-21

Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-21 with Medical categories.


This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.



Childhood Leukemia


Childhood Leukemia
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Author : Gregory H. Reaman
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-01-18

Childhood Leukemia written by Gregory H. Reaman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-18 with Medical categories.


This book is a comprehensive and up-to-date compendium on all aspects of childhood leukemia. After introductory chapters on the epidemiology and biology of pediatric leukemia, treatment considerations are extensively reviewed, with emphasis on the use of risk-adjusted treatment approaches. Promising targeted agents are discussed, and strategies for the development of new agents are appraised. The late effects of leukemia and its therapy are then considered in depth, with due attention to management of the psychosocial impact of the disease. Finally, global strategies to improve leukemia care and outcome are reviewed, and future directions discussed. The authors are internationally recognized experts and offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of pediatric leukemia and will prove invaluable to specialists, generalists, and trainees alike.



Childhood Leukemia Present Problems And Future Prospects


Childhood Leukemia Present Problems And Future Prospects
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Author : Noburo Kobayashi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Childhood Leukemia Present Problems And Future Prospects written by Noburo Kobayashi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Twenty years ago when Children's Cancer Association of Japan was born, the diagnosis of childhood leukemia amounted to a death sentence. Only 20% or so of children with leukemia survived more than 5 years. Since then, enormous improvements have been achieved regarding our understanding on the etiology, diagnosis, and the treatment of childhood leukemia. Now, 70% of children with leukemia survive and enter adult life. Even though the improved survival rate of children with leukemia represents a medical success story, we now face new problems. The first problem is the fact that we still lose 20-30% of patients with childhood leukemia. To address this problem, we need to understand the etiology, epidemiology, and biology of leukemia; to identify the patients at greater risk; and to develop adequate treatments. The second problem is the treatment itself. Even though efficacious, the modem treatment for leukemia is a grueling experience for children and their families. We should develop a total care system for families and children based on a deep understanding of their needs. The third problem is the aftereffects of the treatment and of cured leukemia. Extensive radiation and chemotherapy have an entirely different spectrum of long-term effects on children than on adults. These treatments in the early stage of life, when the mind and body are developing, create many physical and psychological problems. These are the present problems of childhood leukemia.



Childhood Leukemias


Childhood Leukemias
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Author : Ching-Hon Pui
language : en
Publisher: Cambridge University Press
Release Date : 2012-06-21

Childhood Leukemias written by Ching-Hon Pui and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-21 with Health & Fitness categories.


The most comprehensive, clinically-oriented and authoritative reference dedicated to these diseases, from basic science to clinical management.



Risk Factors For Acute Leukemia In Children


Risk Factors For Acute Leukemia In Children
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Author : Martin Belson
language : en
Publisher:
Release Date : 2007-08-01

Risk Factors For Acute Leukemia In Children written by Martin Belson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-01 with categories.


A collection of mini-monographs on childhood cancer: (1) ¿Risk Factors for Acute Leukemia in Children: A Review,¿ by Martin Belson, Beverly Kingsley, & Adrianne Holmes; (2) ¿Infectious Etiologies of Childhood Leukemia: Plausibility & Challenges to Proof,¿ by Siobhan M. O¿Connor & Roumiana S. Boneva; (3) ¿Investigating Childhood Leukemia in Churchill County, Nevada,¿ by Carol S. Rubin et al; (4) ¿Genetic Studies of a Cluster of Acute Lymphoblastic Leukemia Cases in Churchill County, Nevada,¿ by Karen K. Steinberg et al; & (5) ¿An Update on Cancer Cluster Activities at the Centers for Disease Control & Prevention,¿ by Beverly S. Kingsley, Karen L. Schmeichel, & Carol H. Rubin. Illus.



Pediatric Acute Lymphoblastic Leukemia


Pediatric Acute Lymphoblastic Leukemia
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Author : Motohiro Kato
language : en
Publisher: Springer Nature
Release Date : 2019-11-26

Pediatric Acute Lymphoblastic Leukemia written by Motohiro Kato and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-26 with Medical categories.


This book discusses key aspects of childhood acute lymphoblastic leukemia (ALL), presenting the latest research on the biology and treatment of the disease and related issues. The cure rate for ALL has improved dramatically due to advances such as supportive care, treatment stratification based on relapse risk, and the optimization of treatment regimens. Gathering contributions by eminent scholars Pediatric Acute Lymphoblastic Leukemia is a valuable resource for pediatric hematologists as well as for medical students, interns, residents and fellows. It not only offers comprehensive insights, but also provides a springboard for future research.



Hematology


Hematology
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Author : Ronald Hoffman
language : en
Publisher:
Release Date : 2005

Hematology written by Ronald Hoffman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Blood categories.




Childhood Leukemia


Childhood Leukemia
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Author : Gregory H. Reaman
language : en
Publisher: Springer
Release Date : 2010-12-01

Childhood Leukemia written by Gregory H. Reaman and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-01 with Medical categories.


This book is a comprehensive and up-to-date compendium on all aspects of childhood leukemia. After introductory chapters on the epidemiology and biology of pediatric leukemia, treatment considerations are extensively reviewed, with emphasis on the use of risk-adjusted treatment approaches. Promising targeted agents are discussed, and strategies for the development of new agents are appraised. The late effects of leukemia and its therapy are then considered in depth, with due attention to management of the psychosocial impact of the disease. Finally, global strategies to improve leukemia care and outcome are reviewed, and future directions discussed. The authors are internationally recognized experts and offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of pediatric leukemia and will prove invaluable to specialists, generalists, and trainees alike.