Evidence Based Management Of Sickle Cell Disease

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Evidence Based Management Of Sickle Cell Disease

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Author : M D George R Buchanan
language : en
Publisher: Createspace Independent Publishing Platform
Release Date : 2014-09-09

Evidence Based Management Of Sickle Cell Disease written by M D George R Buchanan and has been published by Createspace Independent Publishing Platform this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-09 with Sickle cell anemia categories.

Sickle cell disease can be severe and disabling. When properly treated, patients live longer and with better quality life. This is a US government publication intended to provide evidence-based guidelines for the care of these patients for the use of all concerned providers as well as patients and family members. This book is available in print here for convenience.

Evidence Based Management Of Sickle Cell Disease Expert Panel Report 2014

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Author : U. S. Dept of Health and Human Services
language : en
Publisher:
Release Date : 2018-07-17

Evidence Based Management Of Sickle Cell Disease Expert Panel Report 2014 written by U. S. Dept of Health and Human Services and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-17 with Reference categories.

The purpose of the "Evidence-Based Management of Sickle Cell Disease: Expert Panel Report (EPR), 2014" is to synthesize the available scientific evidence on sickle cell disease and offer guidance to busy primary care clinicians. Readers of this report should remember that this document is intended to provide guidance for management, not to be rigidly prescriptive. The panel recognizes that the responsible clinician's judgment regarding the management of patients remains paramount. Therefore, the Expert Panel Report is a tool to be adopted and implemented in local and individual settings, and to provide an opportunity for shared decision-making in which providers and patients are both fully engaged.

Evidence Based Management Of Sickle Cell Disease

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Author :
language : en
Publisher:
Release Date : 2014

Evidence Based Management Of Sickle Cell Disease written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.

The Management Of Sickle Cell Disease

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Author : U. S. Department of Health
language : en
Publisher: Createspace Independent Publishing Platform
Release Date : 2002

The Management Of Sickle Cell Disease written by U. S. Department of Health and has been published by Createspace Independent Publishing Platform this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Sickle cell anemia categories.

#1 Best Seller on Sickle Cell Disease (SCD). Sickle cell disease is a group of blood disorders passed down from parents to children. Sickle cell anemia shortens life expectancy by 30 years via bacterial infections, painful swellings, fever, arthritis, leg ulcers, eye, lung & heart damage. Over 100,000 people, mostly African-Americans, in the United States have sickle cell disease. Over 2 million people have sickle cell trait in America. It is estimated that more than 300,000 children are born each year with SCD around the world. This edition of The Management of Sickle Cell Disease (SCD) is organized into four parts: 1. Diagnosis and Counseling 2. Health Maintenance 3. Treatment of Acute and Chronic Complications 4. Special Topics. The original intent was to incorporate evidence-based medicine into each chapter, but there was variation among evidence-level scales, and some authors felt recommendations could be made, based on accepted practice, without formal trials in this rare disorder. The best evidence still is represented by randomized, controlled trials (RCTs), but variations exist in their design, conduct, endpoints, and analyses. It should be emphasized that selected people enter a trial, and results should apply in practice specifically to populations with the same characteristics as those in the trial. Randomization is used to reduce imbalances between groups, but unexpected factors sometimes may confound analysis or interpretation. In addition, a trial may last only a short period of time, but long-term clinical implications may exist. Another issue is treatment variation, for example, a new pneumococcal vaccine developed after the trial, which has not been tested formally in a sickle cell population. Earlier trial results may be accepted, based on the assumption that the change is small. In some cases, RCTs cannot be done satisfactorily (e.g., for ethical reasons, an insufficient number of patients, or a lack of objective measures for sickle cell "crises"). Thus the bulk of clinical experience in SCD still remains in the moderately strong and weaker categories of evidence. Not everyone has an efficacious outcome in a clinical trial, and the frequency of adverse events, such as with long-term transfusion programs or hematopoietic transplants, might not be considered. Thus, an assessment of benefit-to-risk ratio should enter into translation of evidence levels into practice recommendations. A final issue is that there may be two alternative approaches that are competitive (e.g., transfusions and hydroxyurea). In this case the pros and cons of each course of treatment should be discussed with the patient. This book is B&W copy of the government agency publication.

Addressing Sickle Cell Disease

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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2020-12-22

Addressing Sickle Cell Disease written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-22 with Medical categories.

Sickle cell disease (SCD) is a genetic condition that affects approximately 100,000 people in the United States and millions more globally. Individuals with SCD endure the psychological and physiological toll of repetitive pain as well as side effects from the pain treatments they undergo. Some adults with SCD report reluctance to use health care services, unless as a last resort, due to the racism and discrimination they face in the health care system. Additionally, many aspects of SCD are inadequately studied, understood, and addressed. Addressing Sickle Cell Disease examines the epidemiology, health outcomes, genetic implications, and societal factors associated with SCD and sickle cell trait (SCT). This report explores the current guidelines and best practices for the care of patients with SCD and recommends priorities for programs, policies, and research. It also discusses limitations and opportunities for developing national SCD patient registries and surveillance systems, barriers in the healthcare sector associated with SCD and SCT, and the role of patient advocacy and community engagement groups.

Sickle Cell Pain

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Author : Samir K. Ballas
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2015-06-01

Sickle Cell Pain written by Samir K. Ballas and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-01 with Medical categories.

Sickle Cell Pain is a panoramic, in-depth exploration of every scientific, human, and social dimension of this cruel disease. This comprehensive, definitive work is unique in that it is the only book devoted to sickle cell pain, as opposed to general aspects of the disease. The 752-page book links sickle cell pain to basic, clinical, and translational research, addressing various aspects of sickle pain from molecular biology to the psychosocial aspects of the disease. Supplemented with patient narratives, case studies, and visual art, Sickle Cell Pain’s scientific rigor extends through its discussion of analgesic pharmacology, including abuse-deterrent formulations. The book also addresses in great detail inequities in access to care, stereotyping and stigmatization of patients, the implications of rapidly evolving models of care, and recent legislation and litigation and their consequences.

Sickle Cell Disease

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Author : Baba P.D. Inusa
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-11-10

Sickle Cell Disease written by Baba P.D. Inusa and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-10 with Medical categories.

This book addresses a wide range of clinically relevant topics and issues in sickle cell disease. This is written by experts in their own field offering a robust, engaging discussion about the presentations and mechanisms of actions in the multiple complications associated with sickle cell disease. This first of the series addresses pain, which is considered the hallmark of sickle cell presentation. It looks at the basic mechanism of pain in sickle cell disease. A more detailed review of precision medicine gives a clear well laid out presentation that is incisive and yet gives in-depth detail relevant to both the clinician and the researcher in the basic laboratory. The same pattern is shown in the discussion on respiratory, cardiac and neurological complications. The 14 chapters also include an overview of sickle cell disease especially in the paediatric age. The content is organized into well-designed broad sections on overview regarding diagnosis including point of care and the role of digital apps in patient management. A key aspect of the book is the opportunity it affords expert physicians to express well-reasoned opinions regarding complex issues in sickle cell disease. The readership would find that it provides a well-described, concise and immediate applicable answers to complex questions. This is highly recommended for scientists and clinicians alike.

The Ebmt Handbook

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Author : Nicolaus Kröger
language : en
Publisher:
Release Date : 2020-10-08

The Ebmt Handbook written by Nicolaus Kröger and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-08 with Medical categories.

This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Evidence Based Neuroimaging Diagnosis And Treatment

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Author : L. Santiago Medina
language : en
Publisher: Springer
Release Date : 2013-04-03

Evidence Based Neuroimaging Diagnosis And Treatment written by L. Santiago Medina and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-03 with Medical categories.

Evidence-Based Neuroimaging is a user-friendly guide that employs evidence-based medicine criteria to systematically review the evidence defining the appropriate use of medical imaging for the brain, spine, head, and neck. Edited by L. Santiago Medina, Pina C. Sanelli, and Jeffrey G. Jarvik, the book provides a systematic framework for understanding the best imaging choices for patient care. Chapters highlight key points that support clinical applications, allowing fast access to pertinent information including patient selection, imaging strategies, test performance, cost-effectiveness, and applicability. The diagnostic imaging of many common diseases, disorders, and conditions are covered, including multiple sclerosis, acute ischemic stroke, dementia, Alzheimer’s disease, traumatic brain injury, autism, spinal trauma, spinal infections, neck masses, thyroid cancer, and cervical lymph node metastasis. By offering a clear understanding of the science behind the evidence, the book fills a void for radiologists, neurologists, neurosurgeons, pediatricians, primary care physicians, and other clinicians with an interest in neuroimaging and a desire to implement an evidence-based approach into their daily practice.

Disorders Of Hemoglobin

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Author : Martin H. Steinberg
language : en
Publisher: Cambridge University Press
Release Date : 2009-08-17

Disorders Of Hemoglobin written by Martin H. Steinberg and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-08-17 with Medical categories.

Completely revised new edition of the definitive reference on disorders of hemoglobin.