Evolving Methods For Macromolecular Crystallography


Evolving Methods For Macromolecular Crystallography
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Evolving Methods For Macromolecular Crystallography


Evolving Methods For Macromolecular Crystallography
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Author : Randy J. Read
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-07-20

Evolving Methods For Macromolecular Crystallography written by Randy J. Read and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-20 with Science categories.


This volume draws on the expertise of leaders in the field of macromolecular crystallography to illuminate the dramatic developments that are accelerating progress in structural biology. Their contributions span the range of techniques from crystallization through data collection, structure solution and analysis. The book shows how modern high-throughput methods are contributing to a deeper understanding of medical problems.



Evolving Methods For Macromolecular Crystallography


Evolving Methods For Macromolecular Crystallography
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Author : Randy J. Read
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-06-25

Evolving Methods For Macromolecular Crystallography written by Randy J. Read and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-06-25 with Computers categories.


This volume draws on the expertise of leaders in the field of macromolecular crystallography to illuminate the dramatic developments that are accelerating progress in structural biology. Their contributions span the range of techniques from crystallization through data collection, structure solution and analysis. The book shows how modern high-throughput methods are contributing to a deeper understanding of medical problems.



Macromolecular Crystallography


Macromolecular Crystallography
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Author : Mark R. Sanderson
language : en
Publisher: Oxford University Press
Release Date : 2007-08-23

Macromolecular Crystallography written by Mark R. Sanderson and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-23 with Language Arts & Disciplines categories.


Macromolecular crystallography is the study of macromolecules using X-ray crystallographic techniques to determine their molecular structure. This title synthesises contributions from a team of internationally recognized leaders, offering chapters on conventional and high-throughput methods.



Methods In Macromolecular Crystallography


Methods In Macromolecular Crystallography
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Author : North Atlantic Treaty Organization. Scientific Affairs Division
language : en
Publisher: IOS Press
Release Date : 2001

Methods In Macromolecular Crystallography written by North Atlantic Treaty Organization. Scientific Affairs Division and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Science categories.


This volume contains 20 papers from two courses ("Methods for Macromolecular Crystallography" and "Chemical Prospective in Crystallography of Molecular Biology") held during the late spring of 2000 in Reice, Italy. The papers discuss crystals, synchrotrons, detector development, data processing, ab initio phasing and high and low resolution, molecular placement, experimental phase measurement, density modification methods, map improvements, interpretation of electron density maps, automatic structure determination, and the dissection of ultra-high resolution structures. c. Book News Inc.



Macromolecular Crystallography Part C


Macromolecular Crystallography Part C
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Author : Charles W. Carter Jr.
language : en
Publisher: Elsevier
Release Date : 2003-12-15

Macromolecular Crystallography Part C written by Charles W. Carter Jr. and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-12-15 with Science categories.


Accurate molecular structures are vital for rational drug design and for structure-based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding. * Methodological methods in crystals* Methodological methods data analysis



Introduction To Macromolecular Crystallography


Introduction To Macromolecular Crystallography
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Author : Alexander McPherson
language : en
Publisher: John Wiley & Sons
Release Date : 2011-09-20

Introduction To Macromolecular Crystallography written by Alexander McPherson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-20 with Science categories.


A comprehensive and approachable introduction to crystallography — now updated in a valuable new edition The Second Edition of this well-received book continues to offer the most concise, authoritative, and easy-to-follow introduction to the field of crystallography. Dedicated to providing a complete, basic presentation of the subject that does not assume a background in physics or math, the book's content flows logically from basic principles to methods, such as those for solving phase problems, interpretation of Patterson maps and the difference Fourier method, the fundamental theory of diffraction and the properties of crystals, and applications in determining macromolecular structure. This new edition includes a vast amount of carefully updated materials, as well as two completely new chapters on recording and compiling X-ray data and growing crystals of proteins and other macromolecules. Richly illustrated throughout to clarify difficult concepts, this book takes a non-technical approach to crystallography that is ideal for professionals and graduate students in structural biology, biophysics, biochemistry, and molecular biology who are studying the subject for the first time.



Macromolecular Crystallography Protocols Volume 2


Macromolecular Crystallography Protocols Volume 2
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Author : Sylvie Doublie
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-05

Macromolecular Crystallography Protocols Volume 2 written by Sylvie Doublie and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-05 with Science categories.


In the decade since publication of the first edition this book, the field has seen several major developments. These developments have both accelerated the pace of structure determination and made crystallography accessible to a broader range of investigators. Volume I is dedicated to crystallization and ways to increase the odds of obtaining crystals in macromolecules. Volume 2 covers both computational methods for characterizing crystals and solving structures.



Macromolecular Crystallography Protocols Volume 1


Macromolecular Crystallography Protocols Volume 1
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Author : Sylvie Doublie
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-04

Macromolecular Crystallography Protocols Volume 1 written by Sylvie Doublie and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-04 with Science categories.


Macromolecular Crystallography Protocols, now in two volumes, examines major developments that have occurred since publication of the acclaimed first edition nearly a decade ago. Volume 1 is composed of detailed protocols for the preparation and optimization of crystals. Volume 2 complements the first volume by addressing laboratory techniques for crystal handling and structural characterization. The volume concludes with a survey of available crystallographic software.



Macromolecular Crystallization And Crystal Perfection


Macromolecular Crystallization And Crystal Perfection
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Author : Naomi E Chayen
language : en
Publisher: OUP Oxford
Release Date : 2010-03-25

Macromolecular Crystallization And Crystal Perfection written by Naomi E Chayen and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-25 with Science categories.


Structural biology is key to our understanding of the mechanisms of biological processes. This book describes current methods and future frontiers in crystal growth and use of X-ray and Neutron crystallography, in the context of the very successful current automation of crystallization and generation of synchrotron X-ray and neutron beams.



Advancing Methods For Biomolecular Crystallography


Advancing Methods For Biomolecular Crystallography
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Author : Randy Read
language : en
Publisher: Springer
Release Date : 2013-04-03

Advancing Methods For Biomolecular Crystallography written by Randy Read and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-03 with Science categories.


This work presents a snapshot of the state of the art of modern biomolecular crystallography, from crystallisation through structure determination and even interactive presentation on the web. Methods driving the latest automated structure determination pipelines are explained, as well as how to deal with problems such as crystal pathologies that still demand expert analysis. These methods are illustrated through their application to problems of great biological interest, such as the molecular machinery underlying the complement pathway, the mechanism of action of monoamine oxidase inhibitors, and the structure of the eukaryotic ribosome. Complementary approaches, such as neutron diffraction, small angle X-ray scattering, coherent diffraction and computational modelling, are also explored.