Examining Genetic And Epigenetic Regulation In Cardiovascular Development Regeneration And Disease
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Examining Genetic And Epigenetic Regulation In Cardiovascular Development Regeneration And Disease
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Author : Eltyeb Abdelwahid
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-06
Examining Genetic And Epigenetic Regulation In Cardiovascular Development Regeneration And Disease written by Eltyeb Abdelwahid and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-06 with Medical categories.
Epigenetics In Cardiovascular Disease
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Author : Yvan Devaux
language : en
Publisher: Elsevier
Release Date : 2021-03-10
Epigenetics In Cardiovascular Disease written by Yvan Devaux and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-10 with Medical categories.
Epigenetics in Cardiovascular Disease, a new volume in the Translational Epigenetics series, offers a comprehensive overview of the epigenetics mechanisms governing cardiovascular disease development, as well as instructions in research methods and guidance in pursing new studies. More than thirty international experts provide an (i) overview of the epigenetics mechanisms and their contribution to cardiovascular disease development, (i) high-throughput methods for RNA profiling including single-cell RNA-seq, (iii) the role of nucleic acid methylation in cardiovascular disease development, (iv) epigenetic actors as biomarkers and drug targets, (v) and the potential of epigenetics to advance personalized medicine. Here, readers will discover strategies to combat research challenges, improve quality of their epigenetic research and reproducibility of their findings. Additionally, discussion of assay and drug development for personalized healthcare pave the way for a new era of understanding in cardiovascular disease. Offers a thorough overview of role of epigenetics mechanisms in cardiovascular disease Includes guidance to improve research plans, experimental protocols design, quality and reproducibility of results in new epigenetics research Explores biomarkers and drug targets of therapeutic potential to advance personalized healthcare Features chapter contributions from a wide range of international researchers in the field
Aldosterone Mineralocorticoid Receptor
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Author : Brian Harvey
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-09-25
Aldosterone Mineralocorticoid Receptor written by Brian Harvey and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-25 with Medical categories.
This book is an open access dissemination of the EU COST Action ADMIRE in Aldosterone/Mineralocorticoid Receptor (MR) physiology and pathophysiology. Aldosterone is the major hormone regulating blood pressure. Alterations in blood levels of aldosterone and genetic mutations in the MR receptor are major causes of hypertension and comorbidities. Many of the drugs in clinical use, and in development for treating hypertension, target aldosterone and MR actions in the kidney and cardiovascular system. The ADMIRE book assembles review chapters from 16 European ADMIRE laboratories providing the latest insights into mechanisms of aldosterone synthesis/secretion, aldosterone/MR physiology and signaling, and the pathophysiological roles of aldosterone/MR activation.
Systems Biology Of Cancer
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Author : Sam Thiagalingam
language : en
Publisher: Cambridge University Press
Release Date : 2015-04-09
Systems Biology Of Cancer written by Sam Thiagalingam and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-09 with Mathematics categories.
An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.
Introduction To Epigenetics
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Author : Renato Paro
language : en
Publisher: Springer Nature
Release Date : 2021-03-23
Introduction To Epigenetics written by Renato Paro and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-23 with Science categories.
This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease
Exercise For Cardiovascular Disease Prevention And Treatment
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Author : Junjie Xiao
language : en
Publisher: Springer
Release Date : 2017-11-02
Exercise For Cardiovascular Disease Prevention And Treatment written by Junjie Xiao and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-02 with Medical categories.
The book provides an intensive overview on exercise for cardiovascular disease prevention and treatment, from basic research to clinical practice. The volume firstly summarizes the acute and chronic response to exercise. Secondly, evidence for exercise as medicine for the heart based on clinical studies and basic research is summarized. Thirdly, molecular mechanisms mediating the beneficial effects of exercise including IGF-1-PI3K-AKT signalling, NO signalling, C/EBPB-Cited4 signalling, Non-coding RNAs, epigenetic regulators, mitochondria adaption and exosomes are presented. Finally, exercise dosing, prescription and future prospects are provided. This book will provide valuable reference for researchers in cell biology, physiology, as well as physician, physical therapist in cardiology, sport medicine, etc.
Epigenetics Of Aging
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Author : Trygve O. Tollefsbol
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-11-11
Epigenetics Of Aging written by Trygve O. Tollefsbol and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-11 with Medical categories.
Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.
Mastering Genetics Unraveling The Code Of Life
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Author : Dominic Front
language : en
Publisher: Richards Education
Release Date :
Mastering Genetics Unraveling The Code Of Life written by Dominic Front and has been published by Richards Education this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medical categories.
Delve into the intricate world of genetics with "Mastering Genetics: Unraveling the Code of Life." This comprehensive guide offers a captivating journey through the fundamental principles, cutting-edge research, and ethical considerations of genetics. From Mendelian inheritance to molecular genetics, population genetics to human genetics, epigenetics to comparative genomics, each chapter provides in-depth explanations, practical applications, and thought-provoking discussions. Explore the timeless laws of inheritance laid down by Gregor Mendel, the molecular mechanisms underlying DNA replication and gene expression, and the revolutionary advances in genetic engineering and gene editing. Gain insights into the fascinating diversity of life forms, from microbes to humans, and discover how genetics shapes our understanding of evolution, biodiversity, and disease. With engaging case studies, illustrative examples, and informative graphics, "Mastering Genetics" equips readers with the knowledge and skills needed to navigate the complexities of genetics in the modern world. Whether you're a student, researcher, or enthusiast, this book will inspire you to unlock the secrets of the genome and appreciate the profound impact of genetics on society, health, and the environment. Embark on a transformative journey into the heart of genetics and embark on a quest to master the code of life.
Epigenetics In Psychiatry
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Author : Jacob Peedicayil
language : en
Publisher: Academic Press
Release Date : 2021-08-21
Epigenetics In Psychiatry written by Jacob Peedicayil and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-21 with Science categories.
Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics, transcriptomics, and proteomics. The book acts as a catalyst for further research in this growing area of psychiatry. This new edition has been fully revised to address recent advances in epigenetic understanding of psychiatric disorders, evoking data consortia (e.g., CommonMind, ATAC-seq), single cell analysis, and epigenome-wide association studies to empower new research. The book also examines epigenetic effects of the microbiome on psychiatric disorders, and the use of neuroimaging in studying the role of epigenetic mechanisms of gene expression. Ongoing advances in epigenetic therapy are explored in-depth. Fully revised to discuss new areas of research across neuronal stem cells, cognitive disorders, and transgenerational epigenetics in psychiatric disease Relates broad advances in psychiatric epigenetics to a modern understanding of the genome, transcriptome, and proteins Catalyzes knowledge discovery in both basic epigenetic biology and epigenetic targets for drug discovery Provides guidance in research methods and protocols, as well how to employ data from consortia, single cell analysis, and epigenome-wide association studies (EWAS) Features chapter contributions from international leaders in the field
Cardiac Regeneration
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Author : Masaki Ieda
language : en
Publisher: Springer
Release Date : 2017-10-27
Cardiac Regeneration written by Masaki Ieda and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-27 with Medical categories.
This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.