Experimental And Comparative Toxicology
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Experimental And Comparative Toxicology
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Author : Charles E. Cornelius
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Experimental And Comparative Toxicology written by Charles E. Cornelius and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.
Experimental and Comparative Toxicology, Volume 31 aims to explore some of the potentially important and crucial areas in experimental toxicology. The book discusses tumor promoters and genotoxic chemicals in short-term testing for carcinogenicity, as well as the significance of preneoplastic liver lesions in experimental animals. The text also describes the factors known to be associated with increased risk of liver neoplasia as a human disease, and the extent to which it is known that the same factors have a similar effect in laboratory animals. Neurobehavioral toxicology; immunotoxicology; and the endocrine system as the target in experimental toxicology are also considered. The book further tackles the uses of gamma-glutamyltransferase in experimental toxicology, as well as the predictive value of ocular irritation tests. Toxicologists, biochemists, pathologists, and those involved in preventive medicine and community health will find the text invaluable.
Toxicology Of Pesticides
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Author : Lucio G. Costa
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Toxicology Of Pesticides written by Lucio G. Costa and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
The protection of human health and food and fiber resources against the ravages of pests of many sorts is a continuous struggle by all people in the world. The use of chemical pesticides as an aid in this struggle is now also global. These chemicals are deliberately added to the environment for the purpose of killing or injuring some form of life. Because pesticides are generally less selectively toxic than would be desired, non-target species, including humans, must be protected from injury by these chemicals. This can only be achieved by thorough understanding of the comparative toxicology of these compounds, and by minimizing human (and other desirable species) exposure. The latter can only be achieved by sound regulatory policies that utilize scientific principles and data, properly tempered by both gaps in that data and sociologic and economic considerations. This book contains the proceedings of the NATO Advanced Study Institute on "Toxicology of Pesticides: Experimental, Clinical and Regulatory Perspectives" held in Riva del Garda on October 6-15, 1986. This NATO-ASI has been promoted by the School of Public Health and Community Medicine, University of Washington at Seattle, by the Institute of Pharmacological Sciences, University of Milano and by the Giovanni Lorenzini Foundation, and has been sponsored by both the Society of Toxicology (USA) and the Italian Society of Toxicology.
Comparative Toxicogenomics
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Author :
language : en
Publisher: Elsevier
Release Date : 2008-07-11
Comparative Toxicogenomics written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-07-11 with Science categories.
Functional genomics has come of age. No longer is it an adventure for the avant garde scientist, but it has become an increasingly standardized mainstream tool accessible to any modern biological laboratory. Toxicogenomics studies are now generating an avalanche of data that, with the aid of established informatics methodology, is being translated into biologically meaningful information. This is enabling us to start harvesting the benefits from years of investment in terms of technology, time, and (of course) money. It is therefore timely to bring together leading toxicologists with a wide variety of scientific aims in this book to demonstrate how microarray technology can be successfully applied to different research areas. This book transects biology from bacteria to human, from ecologically relevant sentinel organisms to well-characterized model species, and represents the full toxicogenomics arena from exploratory "blue sky" science to the prospects for incorporation into regulatory frameworks. * Reviews some of the first really fruitful studies made in this area * Covers different organisms ranging from humans to model species and environmental sentinels * Provides a broad view of the area, increasing its attractiveness to researchers working in a variety of specialties
Animal Models In Toxicology
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Author : Shayne C. Gad
language : en
Publisher: CRC Press
Release Date : 1992-06-11
Animal Models In Toxicology written by Shayne C. Gad and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-06-11 with Nature categories.
Providing step-by-step procedures specifically adapted to each of the major animal model species and describing the basic in vivo techniques used in toxicology and pharmacology, this single-source reference presents the information necessary to select appropriate in vivo models, design experiments, and interpret experimental results.;Furnishing physiological, preproductive, histopathological, clinical pathology, and anaesthesia data for the major laboratory species, Animal Models in Toxicology supplies a historical overview; discusses proper dosing techniques; examines common background diseases; details distinctive metabolic characteristics; demonstrates how to extrapolate results; and explicates animal welfare regulations.;With over 2600 literature citations and an appendix that lists the major commercial sources of laboratory animals, Animal Models in Toxicology is a comprehensive reference for toxicologists, pharmacologists, physiologists, and biochemists in pharmaceutical, clinical, biotechnology and contract laboratories; laboratory animal scientists and technicians; and upper-level undergraduate and graduate courses in animal pharmacology, experimental toxicology, comparative physiology, and experimental procedure.
Searching International Databases
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Author : Jane King
language : en
Publisher: [London] : British Library Board
Release Date : 1983
Searching International Databases written by Jane King and has been published by [London] : British Library Board this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Information storage and retrieval systems categories.
Arsenic In Drinking Water
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2001-11-26
Arsenic In Drinking Water written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-11-26 with Nature categories.
Having safe drinking water is important to all Americans. The Environmental Protection Agency's decision in the summer of 2001 to delay implementing a new, more stringent standard for the maximum allowable level for arsenic in drinking water generated a great deal of criticism and controversy. Ultimately at issue were newer data on arsenic beyond those that had been examined in a 1999 National Research Council report. EPA asked the National Research Council for an evaluation of the new data available. The committee's analyses and conclusions are presented in Arsenic in Drinking Water: 2001 Update. New epidemiological studies are critically evaluated, as are new experimental data that provide information on how and at what level arsenic in drinking water can lead to cancer. The report's findings are consistent with those of the 1999 report that found high risks of cancer at the previous federal standard of 50 parts per billion. In fact, the new report concludes that men and women who consume water containing 3 parts per billion of arsenic daily have about a 1 in 1,000 increased risk of developing bladder or lung cancer during their lifetime.
Toxicity Bibliography
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Author :
language : en
Publisher:
Release Date : 1972
Toxicity Bibliography written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1972 with Drugs categories.
Bioactivity Of Engineered Nanoparticles
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Author : Bing Yan
language : en
Publisher: Springer
Release Date : 2017-08-17
Bioactivity Of Engineered Nanoparticles written by Bing Yan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-17 with Technology & Engineering categories.
This book brings together reviews from international experts who are exploring the biological activities of nanomaterials for medical applications or to better understand nanotoxicity. Topics include but are not limited to the following: 1) mechanistic understanding of nanostructure-bioactivity relationships; 2) the regulation of nanoparticles’ bioactivity by means of chemical modification; 3) the new methodologies and standard methods used to assess nanoparticles’ bioactivity; 4) the mechanisms involved in nanoparticle-biomolecule interactions and nanoparticle-cell interactions; and 5) biomedical applications of nanotechnology. The book will be a valuable resource for a broad readership in various subfields of chemical science, engineering, biology, environment, and medicine.
Behavioral Toxicology
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Author : Bernard Weiss
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Behavioral Toxicology written by Bernard Weiss and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
Behavioral toxicology is a young discipline in the United States; so young, in fact, that this is one of its first books. Behavioral questions are bound to play a major role in future scientific work and governmental decisions involving the health effects of environmental contaminants and other chemicals. This role springs from two key problems that face scientists and public agencies required to set acceptable exposure standards or to determine criteria for the toxicity of therapeutic chemicals: How do you evaluate effects that may show up only as subtle functional disturbances? And how do you de tect toxic effects early enough so that they may still be reversible, before they produce major damage? The contributions in this book come from a collection of scientists whose interests span a wide variety of problem areas. The focus is largely on me thodological issues because they represent the most immediate concern of the discipline. We expect that this collection of papers will represent a useful source book for behavioral toxicology for some time. For the past few years, the University of Rochester's Department of Radiation Biology and Biophysics has sponsored a series of international conferences on chemical toxicity, partly as a response to concern over the con sequences to health of the rich chemical soup in which we live. This book is based upon presentations made to the fifth of the series. Held in June, 1972, it was the first formal meeting devoted to behavioral toxicology in this country.
Animal Experimentation Working Towards A Paradigm Change
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Author : Kathrin Herrmann
language : en
Publisher: BRILL
Release Date : 2019-04-30
Animal Experimentation Working Towards A Paradigm Change written by Kathrin Herrmann and has been published by BRILL this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-30 with Philosophy categories.
Animal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans. Despite this rationale for continued animal experimentation, shortcomings of this practice have become increasingly more apparent and well-documented. However, these limitations are not yet widely known or appreciated, and there is a danger that they may simply be ignored. The 51 experts who have contributed to Animal Experimentation: Working Towards a Paradigm Change critically review current animal use in science, present new and innovative non-animal approaches to address urgent scientific questions, and offer a roadmap towards an animal-free world of science.