Experimental Animal Models Of Human Diseases

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Experimental Animal Models Of Human Diseases

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Author : Bartholomew Ibeh
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-05-23

Experimental Animal Models Of Human Diseases written by Bartholomew Ibeh and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-23 with Science categories.

The world has recorded losses in terms of human life as well as extensive time spent in experimentation with development of new drugs, elucidation of disease mechanism(s), and therapeutic agent discovery. Ethical and legal issues cojoin in slowing down scientific discoveries in medicine and biology. The past two (2) decades, therefore, have seen tremendous attempts that largely are successful in developing animal models with the characteristics of mimicking, approximating, or expressing transplanted human organs/tissues. These models or rather approaches seem to be fast, cost-effective, and easy to maintain compared to primates. This book is a collection of expert essays on animal models of human diseases of global interest. A visible objective of the book is to provide real-time experimental approach to scientists, clinicians, ethicists, medicolegal/medical jurisprudence workers, immunologists, postgraduate students, and vaccinologists and informative and multidisciplinary approach for the identification of new therapeutic targets and biomarkers using animal models as well as investigating the pathogenesis and therapeutic strategies of human diseases. An increased understanding of the genetic, molecular, and cellular mechanisms responsible for the development of human diseases has laid out the foundation for the development of rational therapies mainly with animal models.

Experimental Animal Models Of Human Diseases An Effective Therapeutic Strategy

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Author : Ibeh Bartholomew
language : en
Publisher:
Release Date : 2018

Experimental Animal Models Of Human Diseases An Effective Therapeutic Strategy written by Ibeh Bartholomew and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Zoology categories.

The world has recorded losses in terms of human life as well as extensive time spent in experimentation with development of new drugs, elucidation of disease mechanism(s), and therapeutic agent discovery. Ethical and legal issues cojoin in slowing down scientific discoveries in medicine and biology. The past two (2) decades, therefore, have seen tremendous attempts that largely are successful in developing animal models with the characteristics of mimicking, approximating, or expressing transplanted human organs/tissues. These models or rather approaches seem to be fast, cost-effective, and easy to maintain compared to primates. This book is a collection of expert essays on animal models of human diseases of global interest. A visible objective of the book is to provide real-time experimental approach to scientists, clinicians, ethicists, medicolegal/medical jurisprudence workers, immunologists, postgraduate students, and vaccinologists and informative and multidisciplinary approach for the identification of new therapeutic targets and biomarkers using animal models as well as investigating the pathogenesis and therapeutic strategies of human diseases. An increased understanding of the genetic, molecular, and cellular mechanisms responsible for the development of human diseases has laid out the foundation for the development of rational therapies mainly with animal models.

Spontaneous Animal Models Of Human Disease

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Author : Edwin J. Andrews
language : en
Publisher: Elsevier
Release Date : 2012-12-02

Spontaneous Animal Models Of Human Disease written by Edwin J. Andrews and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.

This two-volume work gathers together the diverse information presently available on spontaneous animal models of human disease. In addition to providing a comprehensive review of existing models, the book presents many previous unpublished new models.The scope of this work is limited to spontaneous models. Neoplasia, infectious diseases including parasitism, and nutritionally induced or other types of experimental models have not been included. The sixteen parts of the book are alphabetically arranged according to organ system with over 230 authors contributing to the overall effort. In addition to many illustrations, the book features an extensive bibliography.

Animal Models For The Study Of Human Disease

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Author : Daniel Butzke
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-05-29

Animal Models For The Study Of Human Disease written by Daniel Butzke and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-29 with Medical categories.

The first years of the 21st century have seen an unparalleled progress in biomedical sciences. Several dogmata that haunted scientific debate for decades were easily abandoned, and there is a fundamental shift away from eminence-based toward evidence-based assessment of preclinical models, probing their true value in predicting clinical outcomes of human diseases. Likewise, several new approaches, e.g., stem cell-based, diseases-in-a-dish and organs-on-a-chip and lab-on-a-chip technologies have revitalized the domain of alternatives to animal experimentation. In our review, we portray these and other efforts to bring forth relevant and ethically inoffensive models of human diseases.

Experimental Surgery And Physiology

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Author : Robert J. Adams
language : en
Publisher:
Release Date : 1988

Experimental Surgery And Physiology written by Robert J. Adams and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Diseases categories.

Animal Models For The Study Of Human Disease

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Author : P. Michael Conn
language : en
Publisher: Academic Press
Release Date : 2013-05-29

Animal Models For The Study Of Human Disease written by P. Michael Conn and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-29 with Science categories.

Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, cancer, hypertension, genetic diseases, and diseases of abuse. Organized by disease orientation for ease of searchability Provides information on locating resources, animal alternatives and animal ethics Covers a broad range of animal models used in research for human disease

Animals For Medical Research

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Author : Brij M. Mitruka
language : en
Publisher:
Release Date : 1982

Animals For Medical Research written by Brij M. Mitruka and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Science categories.

This text provides valuable information in selecting and using suitable animal species for research so that the experimental data can be meaningful and relevant to human disease. It will be useful to those involved in experimental biology and medical research.

Animal Models Of Human Disease

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Author :
language : en
Publisher: Academic Press
Release Date : 2011-03-31

Animal Models Of Human Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-31 with Science categories.

Animal experiments have contributed much to our understanding of mechanisms of disease and are important for determining new therapies. Animal Models of Human Disease reviews the latest research and developments in this field. Discusses new discoveries, approaches, and ideas Contributions from leading scholars and industry experts Reference guide for researchers involved in molecular biology and related fields

Overcoming Challenges To Develop Countermeasures Against Aerosolized Bioterrorism Agents

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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2006-08-07

Overcoming Challenges To Develop Countermeasures Against Aerosolized Bioterrorism Agents written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-08-07 with Political Science categories.

The National Institute of Allergy and Infectious Diseases (NIAID) gives the highest priority to developing countermeasures against bioterrorism agents that are highly infective when dispersed in aerosol form. Developing drugs to prevent or treat illnesses caused by bioterrorism agents requires testing their effectiveness in animals since human clinical trials would be unethical. At the request of NIAID, the National Academies conducted a study to examine how such testing could be improved. Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents provides recommendations to researchers on selecting the kinds of animal models, aerosol generators, and bioterrorism agent doses that would produce conditions that most closely mimic the disease process in humans. It also urges researchers to fully document experimental parameters in the literature so that studies can be reproduced and compared. The book recommends that all unclassified data on bioterrorism agent studies-including unclassified, unpublished data from U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID)-be published in the open literature. The book also calls on the U.S. Food and Drug Administration to improve the process by which bioterrorism countermeasures are approved based on the results of animal studies.

Bibliography Of Induced Animal Models Of Human Disease

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Author : Gerald A. Hegreberg
language : en
Publisher:
Release Date : 1980

Bibliography Of Induced Animal Models Of Human Disease written by Gerald A. Hegreberg and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Animal experimentation categories.

Approximately 2800 references to selected English-language books and journal articles intended for the use of investigators using experimental animals. Most titles were published during the 1970's. Classified index.