Experimental Investigation Of The Pulmonary Toxicity Of Polyvinyl Chloride Particles

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Experimental Investigation Of The Pulmonary Toxicity Of Polyvinyl Chloride Particles
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Author : Haiyan Xu
language : en
Publisher: Leuven University Press
Release Date : 2003
Experimental Investigation Of The Pulmonary Toxicity Of Polyvinyl Chloride Particles written by Haiyan Xu and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Medical categories.
"This is a Ph.D. dissertation. Historically, occupational interstitial lung disease was common in workers who had inhaled mineral dusts such as silica, asbestos, and coal. With improved industrial hygiene and reduced mining and use of these agents, heavy e"
Human Airway Smooth Muscle Cells
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Author : Wim Wuyts
language : en
Publisher: Leuven University Press
Release Date : 2003
Human Airway Smooth Muscle Cells written by Wim Wuyts and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Medical categories.
"This is a Ph.D. dissertation. Because of the worldwide burden of bronchial asthma and the recent increase in the use of lung transplantation as a treatment for end-stage lung disease, the importance of chronic inflammatory airway diseases, such as asthma "
Structure Function Relationship Of K Ion Channel Toxins
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Author : Isabelle Huys
language : en
Publisher: Leuven University Press
Release Date : 2004
Structure Function Relationship Of K Ion Channel Toxins written by Isabelle Huys and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Science categories.
"This is a Ph.D. dissertation. Many fundamental processes underlying nerve and muscle excitation, hormone secretion, learning and memory, cell proliferation, sensory transduction and regulation of blood pressure and osmotic balance, are attributed to a div"
A Prospective Study Of Risk Factors For Low Back Disorders In Occupational Settings
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Author : An van Nieuwenhuyse
language : en
Publisher: Leuven University Press
Release Date : 2005
A Prospective Study Of Risk Factors For Low Back Disorders In Occupational Settings written by An van Nieuwenhuyse and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Health & Fitness categories.
Modulation Of Androgen Receptor Activity By P160 Coactivators And A Study Of Environmental Contaminants
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Author : Valerie Christiaens
language : en
Publisher: Leuven University Press
Release Date : 2005
Modulation Of Androgen Receptor Activity By P160 Coactivators And A Study Of Environmental Contaminants written by Valerie Christiaens and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Science categories.
The development, growth and survival of eukaryotic organisms require the proper regulation of tens of thousands of genes. Therefore, a correct temporal and spatial expression of genes is crucial. These expression patterns are controlled by a wide variety of mechanisms, but a major level of gene expression occurs at the transcription initiation process. In this part, the basic mechanisms of eukaryotic gene transcription will be discussed. Contents include: 1) General Introduction, 2) Characterization of the two coactivator interacting surfaces of the androgen receptor and their relative role in transcriptional control, 3) Screening for environmental (anti)androgenic activity, 4) Detection of endocrine disrupting activities in pesticides and polychlorinated biphenyls, and 5) General Discussion / Future Perspectives.
Biochemical And Immuno Histochemical Analysis Of App Processing And Amyloid Pathology In Single And Multiple Transgenic Mice As Models For Alzheimer S Disease
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Author : Tom V. Dooren
language : en
Publisher: Leuven University Press
Release Date : 2006-09
Biochemical And Immuno Histochemical Analysis Of App Processing And Amyloid Pathology In Single And Multiple Transgenic Mice As Models For Alzheimer S Disease written by Tom V. Dooren and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-09 with Medical categories.
Psychomotor Functioning In Anorexia Nervosa
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Author : Guido Pieters
language : en
Publisher: Leuven University Press
Release Date : 2006-09
Psychomotor Functioning In Anorexia Nervosa written by Guido Pieters and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-09 with Psychology categories.
Enhancing Work Resumption Of Patients On Sub Acute Sickness Absence
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Author : Katrien Mortelmans
language : en
Publisher: Leuven University Press
Release Date : 2006-09
Enhancing Work Resumption Of Patients On Sub Acute Sickness Absence written by Katrien Mortelmans and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-09 with Law categories.
Quantification Of Regional Myocardial Deformation Normal Characteristics And Clinical Use In Ischaemic Heart Disease
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Author : Lieven Herbots
language : en
Publisher: Leuven University Press
Release Date : 2006
Quantification Of Regional Myocardial Deformation Normal Characteristics And Clinical Use In Ischaemic Heart Disease written by Lieven Herbots and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Coronary heart disease categories.
Functional Anatomy Of Visual Processing In The Cerebral Cortex Of The Macaque
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Author : Koen Nelissen
language : en
Publisher: Leuven University Press
Release Date : 2006
Functional Anatomy Of Visual Processing In The Cerebral Cortex Of The Macaque written by Koen Nelissen and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.
In this thesis, we examined the monkey cortical regions involved in processing of color, visual motion information, and the recognition of actions done by others. The aim was to gain better insight in the functional organization of the monkey visual cortex using in-house developed functional imaging techniques. Two different functional imaging techniques were used in these studies, the double-label deoxyglucose technique (DG) and functional magnetic resonance imaging (fMRI) in the awake monkey (Chapter 2). Both techniques allow to obtain an overview of stimulus-related neural activity throughout the whole brain, integrated over a limited amount of time. The results of the color experiments (Chapter 3) clearly showed that color related information is processed within a group of areas belonging to the ventral stream, which is involved in the perception of objects. Color-related metabolic activity was observed in visual areas V1, V2, V3, V4 and inferotemporal cortex (area TEO and TE). These findings set to rest the longstanding controversial claims that color would be processed almost selectively in one extrastriate visual area (V4) (Zeki SM, Brain Res 1973 53: 422-427). These results also show the usefulness of whole brain functional mapping techniques, as a complimentary approach to single cell measurements. In Chapter 4, we investigated which regions in the superior temporal sulcus (STS) of the monkey are involved in the analysis of motion. While the caudal part of the STS has been studied extensively, including area MT/V5 and MST, little is known about motion sensitivity in more anterior-ventral STS regions. Using fMRI, we were able to localize and delineate six different motion sensitive regions in the STS. One of these regions, that we termed 1st (lower superior temporal), had not been described so far. We were able to further characterize the six motion sensitive regions, using a wide variety of motion-sensitivity tests. The results of the latter tests suggested that motion related information might be processed along a second pathway within the STS, in addition to the MT-MST path (which is involved in the perception of heading). This second pathway, which includes the more rostral motion sensitive STS regions (FST, 1st and STPm) is possibly involved in the visual processing of biological movements (movements of animate objects) and actions. Finally, we investigated how and where in the monkey brain visual information about actions done is processed (Chapter 5 and 6). We found (Chapter 5) that, in agreement with earlier single unit results, the observation of grasping movements activates several regions in the premotor cortex of the monkey. Remarkable is that these premotor regions predominantly have a motor function, coding different types of higher order motor acts (for instance grasping of an object). These results are in agreement with earlier suggestions that we are able to understand actions done by others, because observation of a particular motor act activates our own motor representation of the same act. Furthermore, these studies suggested that within the frontal cortex of the monkey, there is a distinction between context-dependent (a person grasping) and more abstract (a hand grasping) action representations. In Chapter 6 we studied two other regions which are involved in the processing of visual information of actions done by others, the superior temporal sulcus (STS) and the parietal cortex. In the parietal cortex, we found a similar distinction between context-dependent and more abstract action representations as observed in prefrontal cortex. These results suggest that the parietal cortex is not only involved in the visual control of action planning, but also in the visual processing of actions performed by others. Based upon anatomical connections between the STS, parietal and frontal regions and motion-, form- and action-related functional properties of the former regions, we tentatively suggest how information about actions done by others might be sent from the STS to the frontal cortex along three different pathways. The latter working hypothesis will be tested in the future by additional fMRI control experiments and by combining fMRI, inactivation and microstimulation experiments while monkeys perform grasping tasks and/or view actions performed by others.